Clinical trials: Acetaminophen, completed
Laparoscopic Cholecystectomy, Inguinal Hernia
A Trial Comparing Combination Therapy of Acetaminophen Plus Ibuprofen Versus Tylenol #3 for the Treatment of Pain After Outpatient Surgery
Increasingly in general surgery, the investigators are conducting outpatient day surgery. Ambulatory surgery currently comprises 60 to 70% of surgeries performed in North America.
- Conditions
- Laparoscopic Cholecystectomy, Inguinal Hernia, Abdominal Hernia, Umbilical Hernia
- Trial name
- NCT00245375
- Testing
- Tylenol #3, Combination Tylenol and Ibuprofen
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Nova Scotia Health Authority
Lung Neoplasms, Pain
Supplementary Epidural Analgesia in Video-Assisted Thoracic Surgery (VATS) - The SEAVATS Study
Whereas it, in the case of conventional thoracotomy, has been demonstrated that thoracic epidural analgesia is more effective than systemic opioids in terms of pain relief and preservation of postoperative pulmonary function, the…
- Conditions
- Lung Neoplasms, Pain, Immune Suppression
- Trial name
- SEAVATS (NCT02359175)
- Testing
- Bupivacaine in epidural catheter, Fentanyl in epidural catheter, Oral Paracetamol
- Where
- Denmark
- Volunteers
- 161 people
- Sponsor
- Odense University Hospital
Osteoarthritis
A Study to Evaluate the Effect of Analgesics on a Walking Model of Knee Pain (0000-105)(COMPLETED)
This study will evaluate a walking model of osteoarthritis for use in testing of new therapeutic agents. The primary hypothesis is that participants treated with Naproxen or Ultracet will have lower Pain Intensity (PI) than those…
- Trial name
- NCT00772967
- Testing
- Naproxen, Ultracet
- Volunteers
- 22 people
- Sponsor
- Merck Sharp & Dohme LLC
Office Hysteroscopy
Efficacy of Oral Paracetamol Compared With Oral Ketoprofen for Pain Management in Office Hysteroscopy
Hysteroscopy is a procedure used to evaluate abnormalities within the uterus (intrauterine. Currently, hysteroscopy can be performed in an outpatient clinic setting according to established standards, known as office…
- Trial name
- NCT07315698
- Testing
- Ketoprofen 100mg, Paracetamol 1000 Mg Oral Tablet
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Overweight or Obesity
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-4729 Injection in Healthy Subjects
The study is being conducted to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HRS-4729 injection in healthy subjects.
- Trial name
- NCT06762600
- Testing
- HRS-4729 injection, HRS9531 injection, Acetaminophen
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Pregnancy, Postpartum Period
Sleep Disruption in New Mothers: An Intervention Trial
The purpose of this study is to test a behavioral intervention to minimize sleep disruption and fatigue in new mothers after the birth of their first infant.
- Conditions
- Pregnancy, Postpartum Period, Sleep Disturbance
- Trial name
- MOMS (NCT01321710)
- Testing
- Sleep hygiene, Dietary information, Acetaminophen
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of California, San Francisco
Pain
IV Acetaminophen for Postoperative Pain Analgesia After Laparoscopic Hysterectomy
The objective of this study is to quantify the change in post-operative pain scores and narcotic requirements in women receiving pre and post-operative IV acetaminophen compared to placebo in women undergoing laparoscopic…
- Trial name
- NCT02400580
- Testing
- IV acetaminophen
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Respiratory Tract Infections
To Test Bioequivalence Between Two Formulations of Paracetamol/Phenylephrine
This study is designed to assess bioequivalence between two paracetamol/ phenylephrine combination products.
- Trial name
- NCT01112462
- Testing
- Paracetamol 500 mg/Phenylephrine 5 mg tablets, Paracetamol 1000 mg/Phenylephrine 10 mg sachet
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- McNeil AB
Pyloric Stenosis
Institutional Audit of the Use of Intravenous Acetaminophen in Infants Undergoing Pyloromyotomy
This is a retrospective chart review. The objective of the current study is to determine the analgesic efficacy and side effect profile of intravenous acetaminophen when administered to infants undergoing pyloromyotomy.
- Trial name
- NCT02359305
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Arlyne Thung
Hip Arthroscopy
Nonopioid Pain Control Regimen After Arthroscopic Hip Procedures
This study is being conducted to evaluate the effectiveness of post-operative pain control without using narcotic pain medications.
- Trial name
- NCT05076110
- Testing
- Oxycodone, Ibuprofen, Gabapentin
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Mayo Clinic
Epilepsy, Depression
Measuring Blood Flow in the Brain After Epileptic Activity
In this clinical trial, postictal phenomena (i.e., headache, delirium) will be investigated after administration of acetaminophen and nimodipine in depressed patients receiving electroconvulsive therapy (ECT).
- Conditions
- Epilepsy, Depression, Postictal Delirium, Electroconvulsive Therapy
- Trial name
- SYNAPSE (NCT04028596)
- Testing
- Paracetamol, Nimotop
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Rijnstate Hospital
Healthy Volunteer Study
Ibuprofen and Paracetamol Pharmacokinetic Study
The purpose of this study was to determine rates of absorption of Ibuprofen and Paracetamol formulations.
- Trial name
- NCT02452450
- Testing
- Ibuprofen Acid, Ibuprofen Lysine, Ibuprofen Sodium
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Osteoarthritis
A Study of the Tolerability of Titrated Dose Tramadol/Acetaminophen Combination Tablet in Korean Patients With Osteoarthritis
The purpose of this study is to compare the number of osteoarthritis patients receiving titrated or increasing doses of tramadol hydrochloride/acetaminophen combination tablet (titration group) who discontinue treatment due to…
- Trial name
- NCT01063842
- Testing
- tramadol hydrochloride /acetaminophen
- Volunteers
- 250 people
- Sponsor
- Janssen Korea, Ltd., Korea
Craniotomy, Brain Surgery
The Efficacy of Intravenous Acetaminophen During Perioperative Neurosurgery Period
This is a prospective randomized double blinded trial study involving 128 patients undergoing any craniotomy procedure at Evanston Hospital. The patients will be randomized by the sealed envelope technique.
- Trial name
- NCT01739699
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Endeavor Health
Postoperative Pain, Total Shoulder Arthroplasty
Cohort 1 (TSA) of: A Multi-surgery Assessment of ZYNRELEF (HTX-011)
Cohort 1 (subjects undergoing total shoulder arthroplasty, TSA) of a Phase 4, randomized, blinded, active-controlled, multicohort study to evaluate HTX-011 compared with bupivacaine HCl in subjects undergoing different surgical…
- Conditions
- Postoperative Pain, Total Shoulder Arthroplasty, Multimodal Analgesia
- Trial name
- AMAZE (NCT06109415)
- Testing
- HTX-011, Bupivacaine Hydrochloride, MMA regimen
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Heron Therapeutics
Pain, Postoperative, Urethral Stricture
Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty
The investigator's study aims to see if an enhanced recovery regimen of pain medications before and during surgery will decrease the use and risk of opioid pain medications as well as improve pain control in anterior…
- Trial name
- NCT03859024
- Testing
- Oxycodone, Acetaminophen, Gabapentin
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Alabama at Birmingham
Aspirin Sensitivity, Aspirin-exacerbated Respiratory Disease
Characteristics of Patients Diagnosed With NSAID Sensitivity in Thailand
Study clinical characteristics and phenotypes of patients diagnosed with NSAID sensitivity in Thailand
- Conditions
- Aspirin Sensitivity, Aspirin-exacerbated Respiratory Disease, Aspirin-Induced Angioedema-Urticaria, Aspirin Allergy
- Trial name
- NCT03849625
- Testing
- aspirin, NSAIDs, paracetamol
- Where
- Thailand
- Volunteers
- 158 people
- Sponsor
- Chulalongkorn University
Pain, Postoperative
Single Dose Preoperative Gabapentin Use in Minimally Invasive Hysterectomy for Acute Pain Management
The purpose of the investigators' study is to assess the efficacy of a single dose of preoperative gabapentin within an enhanced recovery after surgery protocol in acute postoperative pain reduction for women undergoing a…
- Trial name
- NCT02703259
- Testing
- Gabapentin, Acetaminophen, Celecoxib
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Hip Fractures, Acute Pain
PENG Block for Traumatic Hip Fracture in the Emergency Department
The study is a multicenter single-blinded randomized comparative trial. Adult patients older than 20 years of age presenting with acute hip fracture in emergency department between January 1st, 2021 and December 31st, 2021 will…
- Conditions
- Hip Fractures, Acute Pain, Emergency Department
- Trial name
- NCT04997785
- Testing
- Ultrasound-guided Pericapsular Nerve Group (PENG) Block
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Dalin Tzu Chi General Hospital
Postoperative Pain, Hysterectomy
Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery
This study will be investigating the efficacy and safety administration of multiple doses of intravenous (IV) acetaminophen (IVAPAP) in the 48 hour period following Gynecologic Surgery.
- Trial name
- NCT00399568
- Testing
- IV Acetaminophen
- Where
- 27 sites in United States
- Volunteers
- 331 people
- Sponsor
- Mallinckrodt
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