Clinical trials: Acetaminophen, completed
Postoperative Pain, Patient Satisfaction
Post Operative Analgesia and Patient Satisfaction
To understand how patients perceive the quality of care they receive when given different post-operative analgesic medications. Specifically the investigators want to assess whether patients who receive non-opioid analgesia…
- Conditions
- Postoperative Pain, Patient Satisfaction, Analgesia
- Trial name
- NCT04976387
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Acute Otitis Media
Four Arm Safety & Efficacy With Antipyrine and Benzocaine Otic Solution in Children With Acute Otitis Media
The primary objective is to compare the effect of treatment with a combination of ear solutions on the reduction of pain symptoms at 1 hour after dosing in children with acute otitis media.
- Trial name
- NCT02037893
- Testing
- Antipyrine and Benzocaine otic solution, Antipyrine Otic Solution, Benzocaine Otic Solution
- Where
- 10 sites in United States
- Volunteers
- 112 people
- Sponsor
- Currax Pharmaceuticals
Hip Arthroplasty, Knee Arthroplasty
Effect of Combined Use of Naloxone and Tramacet on Postop Analgesia in Elderly Patients Having Joint Replacement Surgery
Patients over 70 years of age, scheduled for joint replacement surgery will be randomized to tramacet/ naloxone plus morphine PCA or to morphine PCA to assess quality of analgesia in the postoperative period.
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, Spinal Anesthesia
- Trial name
- NCT00679614
- Testing
- tramacet, naloxone, tramacet, Acetaminophen
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Pain, Cesarean Section
Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery
The primary purpose of this study is to determine whether the addition of a TAP block to standard analgesia after the cesarean delivery will impact postoperative wound healing and attenuate postoperative stress and immune…
- Conditions
- Postoperative Pain, Cesarean Section, Wound Heal
- Trial name
- NCT05840406
- Testing
- Postoperative pain management with acetaminophen, Bilateral TAP Block with levobupivacaine, Bilateral TAP Block with levobupivacaine and dexmedetomidine
- Where
- Croatia
- Volunteers
- 105 people
- Sponsor
- University Hospital Sestre Milosrdnice
Postoperative Pain, Mitral Valve Disease
Postoperative Analgesia After Minithoracotomy
Patients scheduled for minimally invasive mitral valve replacement. Each patient will be treated with intravenous (i.v.) oxycodone - patient-controlled analgesia (PCA).
- Trial name
- NCT03415555
- Testing
- Erector Spinae Plane blockade, Oxycodone, general anesthesia
- Where
- Poland
- Volunteers
- 19 people
- Sponsor
- Medical University of Lublin
Prostatectomy, Pain
Pharmacoeconomics and Related Patient Outcomes of Multi-dose Intravenous Acetaminophen (OFIRMEV)
To examine pharmacoeconomics of IV acetaminophen (Ofirmev). Specifically, to examine its potential to improve hospital efficiency and patient outcomes.
- Trial name
- NCT02369211
- Testing
- Acetaminophen (Ofirmev)
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Healthy
Influence of Age on the Absorption and Metabolism of Cocoa Flavanols
Accumulating evidence suggests that regular consumption of foods and beverages rich in flavanols, such as cocoa, tea, apples and wine, may have cardiovascular benefits.
- Trial name
- NCT01790009
- Testing
- Flavanol rich drink, Acetaminophen
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Progressive Multiple Sclerosis
A Study to Characterize Subcutaneous or Intravenous Alemtuzumab in Patients With Progressive Multiple Sclerosis
Primary Objective: To characterize the pharmacodynamic profile of 2 treatment courses of alemtuzumab administered by subcutaneous injection and 2 treatment courses of alemtuzumab administered by intravenous infusion in patients…
- Trial name
- SCALA (NCT02583594)
- Testing
- Acyclovir, Methylprednisolone, alemtuzumab GZ402673
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Genzyme, a Sanofi Company
Hepatotoxicity
Acetaminophen-induced Hepatotoxicity in Chronic Alcohol Abusers
It is widely believed that people who abuse alcohol can sustain a liver injury after taking doses of acetaminophen just above the recommended maximum dose.
- Trial name
- NCT00137059
- Testing
- acetaminophen sustained-release
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Dr. Marco L.A. Sivilotti
Osteoarthritis
A Comparative Study of Tramadol Hydrochloride Plus Acetaminophen Tablets Maintenance Versus Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Maintenance in Participants With Knee Osteoarthritis
The purpose of this study is to compare the effectiveness of tramadol hydrochloride 37.5 milligram (mg) plus acetaminophen 325 mg maintenance with that of non-steroidal anti-inflammatory drugs (NSAIDs) maintenance in participants…
- Trial name
- NCT00635349
- Testing
- Meloxicam, Aceclofenac, Tramadol Hydrochloride Plus Acetaminophen
- Volunteers
- 143 people
- Sponsor
- Janssen Korea, Ltd., Korea
Adverse Anesthesia Outcome
Preemptive Analgesia Using Intravenous Paracetamol
Dental treatment for children should be done in a calm atmosphere and without pain. Oral Propacetamol has been shown to be effective in a variety of postsurgical pain models.
- Trial name
- NCT02884921
- Testing
- Paracetamol
- Volunteers
- 87 people
- Sponsor
- Bnai Zion Medical Center
Hypertension
Interaction Between Antihypertensives and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
NSAIDs may increase blood pressure and blunt the effects of many antihypertensives. Members of these drug classes differ in their propensity to such an interaction.
- Trial name
- NCT00631514
- Testing
- acetaminophen, ibuprofen, piroxicam
- Where
- Croatia
- Volunteers
- 88 people
- Sponsor
- University of Split
Covid19
Effectiveness of Ivermectin and Doxycycline on COVID-19 Patients
A randomized controlled trial on using Ivermectin and doxycycline to treat mild-moderate outpatients, severe, and critical inpatients of Coronavirus disease 19 (COVID-19) along with standard of care.
- Trial name
- NCT04591600
- Testing
- Ivermectin and Doxycyline, Standard of care
- Where
- Iraq
- Volunteers
- 140 people
- Sponsor
- Alkarkh Health Directorate-Baghdad
Chronic Low Back Pain
A Pilot Study Examining the Efficacy of Biomodulator Treatment for Chronic Low Back Pain
The purpose of this study is to determine the efficacy of self treatment with the Biomodulator device to decrease chronic low back pain (LBP) in active duty service members.
- Trial name
- NCT02707094
- Testing
- Biomodulator, Usual Care (Medication + Exercise)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Brooke Army Medical Center
Emergence Agitation, Pain
Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
The purpose of this study is to compare the incidence of EA in pediatric patients undergoing minor ENT surgery under Sevoflurane and compare opioid-only based intra-operative analgesia to multi-modal analgesia consisting of…
- Trial name
- NCT03062488
- Testing
- IV acetaminophen, Fentanyl, PO acetaminophen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Trauma, Chronic Pain
Pain Multidisciplinar Intervention in Major Trauma Patients
In Spain, major trauma continues to be the leading cause of death among young people. However, mortality rates represent only a relatively small part of the impact of trauma injuries on the health of the population.
- Conditions
- Trauma, Chronic Pain, Psychological Trauma
- Trial name
- NCT05355441
- Testing
- Paracetamol, Ibuprofen 600 mg, Tramadol
- Where
- Spain
- Volunteers
- 38 people
- Sponsor
- Nuria Llorach-Perucho
Pain, Postoperative
PAracetamol and NSAID in Combination: A Randomised, Blinded, Parallel, 4-group Clinical Trial
Trial name: PAracetamol and NSAID in combination: A randomised, blinded, parallel, 4-group clinical trial Trial acronym: PANSAID Background: Effective postoperative pain management is essential for the well-being and…
- Trial name
- PANSAID (NCT02571361)
- Testing
- Paracetamol (1g x 4), Ibuprofen (400 mg x 4), Paracetamol (0,5 g x 4)
- Where
- 6 sites in Denmark
- Volunteers
- 556 people
- Sponsor
- Daniel Hägi-Pedersen
Rotator Cuff Tendonitis
Accuracy of Needle Placement Into The Subacromial Space of The Shoulder
This study attempts to determine the most accurate route for injection of the subacromial bursa in patients with rotator cuff tendonitis. Typically, in medical practice, one of the routes of injection is used.
- Trial name
- NCT01330641
- Testing
- Injection of Subacromial Bursa
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Davis
Pain, Postoperative, Opioid Use
IV vs. Oral Acetaminophen as a Component of Multimodal Analgesia After Total Hip Arthroplasty
The purpose of this study is to determine how well two different methods of administrating Tylenol reduce pain and improve patient satisfaction after total hip replacement (THR) surgery.
- Trial name
- IV Tylenol (NCT03020966)
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Hospital for Special Surgery, New York
Colonoscopy, Pain
Analysis of the Analgesic Mechanism of TENS-WAA During Non-anesthetized Colonoscopy Using EEG-fNIRS System
This study is a single-center, randomized controlled trial aiming to evaluate the analgesic mechanism of Transcutaneous Electrical Nerve Stimulation based on Wrist-Ankle Acupuncture (TENS-WAA) during unsedated colonoscopy using…
- Trial name
- NCT06813703
- Testing
- Using an electrical stimulation device to relieve pain during colonoscopy
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of the Chinese People's Liberation Army Naval Medical University
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