Clinical trials: Acetaminophen, completed
Pain, Postoperative
Perioperative Electroacupuncture on Postoperative Analgesia in Prostatectomy
The aim of the present study is the comparison of the efficacy of the perioperative application of a multimodal analgesia model to the patients, combing common used analgesics via intravenous (IV) route, such as tramadol and…
- Trial name
- NCT01526525
- Testing
- Tramadol, Ketamine, Morphine
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- G.Gennimatas General Hospital
Healthy Volunteers
Pharmacokinetic Study of a Fixed Dose Combination Nefopam Hydrochloride (30 mg) / Paracetamol (500 mg)
This study aims to assess the pharmacokinetic profile of a Fixed Dose Combination nefopam hydrochloride (30 mg) / paracetamol (500 mg) and individual components taken alone or concomitantly after oral single dose.
- Trial name
- ARL/20/277 (NCT05129137)
- Testing
- nefopam hydrochloride 30mg X2, paracetamol 500 mg X2, Combination Product: nefopam hydrochloride 30mg / paracetamol 500mg X2
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Unither Pharmaceuticals, France
Orthodontic Pain
A Study of Acetaminophen/Naproxen Sodium Fixed Combination Tablets in Adolescents 12 to <17 Years of Age With Pain
The purpose of this study is to investigate the population pharmacokinetics of acetaminophen and naproxen from a novel acetaminophen /naproxen sodium fixed combination tablet in adolescents 12 to less than (<) 17 years of age…
- Trial name
- NCT05844995
- Testing
- Acetaminophen/Naproxen Sodium
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Pain, Postoperative
Analgesic Effect of Paracetamol, Paracetamol + Codeine, Ibuprofen and Their Combination
The purpose of this study is to determine whether the combination of paracetamol (acetaminophen) and other NSAIDs with or without weak opioids can give synergistic analgesic effect.
- Trial name
- NCT00921700
- Testing
- Ibuprofen + Paracetamol, Ibuprofen + Paracetamol + Codeine, Paracetamol + Codeine
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Ullevaal University Hospital
Glaucoma
Does Oral Acetaminophen Lower Intraocular Pressure?
Lowering intraocular pressure is the only proven treatment for glaucoma. Medications, almost always in the form of eye drops, are a mainstay for lowering intraocular pressure.
- Trial name
- NCT02366065
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Johns Hopkins University
Postpartum Disorder
Efficacy of Ginger Extract (Compare Between the Ginger Preparation of Ancient Concept of Thai Traditional Practitioner, Standard Drug and Placebo) by Using Pain Score to Evaluate After Pain of Three Groups of First Normal Postpartum Women.
Introduction A common problem in women after childbirth is bleeding (5-8 percent). This is one of the leading causes of maternal death in Thailand.
- Trial name
- NCT03617900
- Testing
- Ginger, Paracetamol
- Where
- Thailand
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Post-Dural Puncture Headache
Different Approaches for the Management of Post-dural Puncture Headache
Detecting the efficacy and safety of trans-nasal sphenopalatine ganglion block using either lidocaine 2% or bupivacaine 0.5 % as a treatment line for post-dural puncture headache
- Trial name
- NCT05253014
- Testing
- sphenopalatine ganglion block, paracetamol
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Bahaa Mohammed Refaie
Acute Dental Pain
Evaluation of the Analgesic Efficacy of the Combination of Dexketoprofen + Paracetamol and the Combination of Naproxen Sodium + Codeine in Patients With Acute Dental Pain
Acute dental pain is one of the most challenging conditions to treat and manage in dental practice. The aim of this study was to compare the efficacy of naproxen sodium + codeine phosphate (550/30 mg) and dexketoprofen trometamol…
- Trial name
- NCT06916234
- Testing
- Dexketoprofen Trometamol + Paracetamol, Naproxen Sodium + Codeine Phosphate
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ibrahim doğru
Malignant Solid Tumor, Pain
Pragmatic Research of Acupuncture and Counseling eXtended to Inpatient Services
Despite improved assessment and pharmacologic management, cancer pain is still undertreated. Using non-pharmacologic treatments alongside medications may better address patients' total pain experience by relieving physical and…
- Trial name
- PRACXIS (NCT03905720)
- Testing
- Acupuncture, Pain Counseling
- Where
- 2 sites in United States
- Volunteers
- 448 people
- Sponsor
- University of California, San Francisco
Healthy
Pharmacokinetics and Bioequivalence of Vycavert (10 mg Hydrocodone Bitartrate/325 mg Acetaminophen) Compared to the Reference Drug Norco
This study aims to determine whether the hydrocodone and acetaminophen exposures following oral dosing of Vycavert are comparable to those following oral dosing of Norco.
- Trial name
- NCT01456520
- Testing
- Vycavert, Norco
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Pfizer
Urolithiasis
Intravenous Paracetamol or Morphine for the Treatment of Acute Flank Pain
STUDY OBJECTIVE: This randomized, controlled trial evaluates the analgesic efficacy and safety of intravenous single-dose paracetamol and morphine for the treatment of acute flank pain.
- Trial name
- NCT01318187
- Testing
- paracetamol, morphine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Pamukkale University
Trauma, Flail Chest
Operative Treatment of Unstable Thoracic Cage Injuries and Chest Wall Deformity in Trauma
The purpose of this prospective controlled study is to determine whether surgical management of unstable thoracic cage injuries and chest wall deformity in trauma reduces the need for and the time spent on ventilator compared to…
- Conditions
- Trauma, Flail Chest, Rib Fractures, Surgery
- Trial name
- NCT02132416
- Testing
- NSAID, Opioids, Thoracic Epidural anaesthesia
- Where
- 2 sites in Sweden
- Volunteers
- 92 people
- Sponsor
- Sahlgrenska University Hospital
Surgery
Analgesic Effect of Ibuprofen, Paracetamol (Acetaminophen), and Paracetamol (Acetaminophen) Plus Codeine on Acute Pain
The purpose of this placebo controlled clinical trial is to evaluate the dose response relationship of ibuprofen in doses from 400 mg to 800 mg and paracetamol (acetaminophen)in doses from 500 mg to 1000 mg compared with…
- Trial name
- NCT00699114
- Testing
- Ibuprofen 400 mg, Ibuprofen 600 mg, Ibuprofen 800 mg
- Where
- Norway
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Functional Gastrointestinal Disorders, Functional Abdominal Pain Syndrome
Targeted Food Elimination for Treatment of Functional Gastrointestinal Diseases in Children
Recurrent Abdominal Pain (RAP) in children is common and causes significant functional impairment and poor quality of life. Lifestyle factors such as diet, anxiety, and stress are important triggers of abdominal pains, but there…
- Conditions
- Functional Gastrointestinal Disorders, Functional Abdominal Pain Syndrome, Abdominal Pain (AP)
- Trial name
- FGID (NCT02565355)
- Testing
- Dietary Exclusion, Standard Treatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Open Heart Surgery, Postoperative Pain
Postoperative Pain Alleviation in Open Heart Surgery
Effective pain relief after cardiac surgery has assumed importance with the introduction of fast track discharge protocols that requires early weaning from mechanical ventilation.
- Trial name
- NCT03106818
- Testing
- bupivacain with magnesium sulphate, Bupivacaine only, conventional
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia
Allo HSCT Using RIC for Hematological Diseases
This is a phase II trial using a non-myeloablative cyclophosphamide/ fludarabine/total body irradiation (TBI) preparative regimen followed by a related or unrelated donor stem cell infusion.
- Conditions
- Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia
- Trial name
- NCT02661035
- Testing
- Allopurinol, Fludarabine, Cyclophosphamide
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Anesthesia, Local, Prolapse
Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy
The purpose of this study is to assess whether the transversus abdominis plane block (Tap block) is different than the oral postoperative pain medications in controlling pain after robotic sacrocolpopexy.
- Conditions
- Anesthesia, Local, Prolapse, Prolapse; Female, Prolapse, Vaginal
- Trial name
- SACROTAP (NCT04440475)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- ProMedica Health System
Pain, Postoperative Arthroscopy
Effect of Rofecoxib and a Narcotic Analgesic to Treat Pain Following Arthroscopic Surgery (0966-179)(COMPLETED)
Study the effect of rofecoxib 50 mg compared to both placebo, and hydrocodone 7.5 mg with acetaminophen 750 mg, to treat moderate to severe pain following arthroscopic knee surgery.
- Trial name
- NCT00390260
- Testing
- MK0966 / Duration of Treatment: 1 Days, Comparator: acetaminophen (+) hydrocodone bitartrate / Duration of Treatment: 1 Days
- Volunteers
- 420 people
- Sponsor
- Merck Sharp & Dohme LLC
Post Mastectomy Pain Syndrome
Comparison Between Pregabalin and Acetaminophen for the Treatment of Post-Mastectomy Pain Syndrome
The goal of this trial is to learn if Pregabalin is better than Acetaminophen in pain management of patients with Post-Mastectomy pain Syndrome, which is defined as pain in the scar, chest wall, shoulder after undergoing…
- Trial name
- NCT07567924
- Testing
- Pregabalin, Acetaminophen
- Where
- Pakistan
- Volunteers
- 158 people
- Sponsor
- Subas Ali
Cesarean Section; Dehiscence
Preemptive Analgesia With Intravenous Paracetamol for Post-cesarean Section Pain Control
The investigators designed a prospective randomized study to investigate the efficacy of intravenous (IV) preemptive paracetamol on postoperative pain scores, patient satisfaction, total morfin consumption and the incidence of…
- Trial name
- NCT02369133
- Testing
- paracetamol
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baskent University
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