Clinical trials: Aerobic Exercise
Osteoarthritis, Overweight and Obesity
Fit and Strong! Plus Comparative Effectiveness Trial
This randomized controlled trial is comparing outcomes of customary Fit and Strong!, to Fit and Strong! Plus, an enhanced version of the program that incorporates weight management.
- Trial name
- NCT03180008
- Testing
- Fit and Strong!, Fit and Strong! Plus
- Where
- United States
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
HIV, Cardiovascular Disease
Healing Hearts and Mending Minds in Older Adults Living With HIV
The purpose of this study is to see if exercise is helpful for improving memory, concentration thinking abilities, physical function, and quality of life for adults aged 50 to 89 years living with HIV and who have two or more…
- Conditions
- HIV, Cardiovascular Disease, AIDS
- Trial name
- FitBrain (NCT02711878)
- Testing
- Let's Move Program, Let's Flex Program, Group Motivational Interviewing
- Where
- 3 sites in United States
- Volunteers
- 115 people
- Sponsor
- Emory University
Major Depressive Disorder
Efficacy of Adjunctive Exercise for the Behavioral Treatment of Major Depression
Major depressive disorder (MDD) is the leading cause of disability in the developed world and is associated with lost productivity, increased health care utilization, and mortality.
- Trial name
- NCT02176408
- Testing
- Behavioral Activation, Exercise Intervention, Stretching Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Boston University Charles River Campus
Delirium, Alzheimer Disease
Improving the Recovery and Outcome Every Day After the ICU
Primary Specific Aim: Determine the effect of the combined physical exercise and cognitive training on the cognitive function of ICU survivors aged 50 and older.
- Trial name
- IMPROVE (NCT03095417)
- Testing
- Physical Exercise Intervention, Cognitive Training Intervention, Stretching Control
- Where
- 6 sites in United States
- Volunteers
- 249 people
- Sponsor
- Indiana University
Obesity, Weight Loss
Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)
Although coronary heart disease (CHD) treatment guidelines recognize obesity as a major modifiable risk factor,2 nearly half of all CHD patients are obese and the current standard of care fails to implement evidence-based obesity…
- Conditions
- Obesity, Weight Loss, CHD - Coronary Heart Disease
- Trial name
- TOPCARE (NCT03423238)
- Testing
- Exercise, Health Education, Exercise Compliance
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Wake Forest University Health Sciences
Peripheral Neuropathy, Diabetes
Reversing Diabetic Peripheral Neuropathy Through Exercise
This project proposes a longitudinal design that uses multinuclear-MRI to evaluate the mechanistic effects of exercise on skeletal muscle function and peripheral nerve integrity in patients with diabetic peripheral neuropathy…
- Trial name
- NCT03686423
- Testing
- Exercise Program
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- NYU Langone Health
Knee Arthroplasty
The PATH Study to Promote Physical Activity After Knee Replacement
The purpose of this study is to examine the feasibility and preliminary efficacy of a physical therapist led physical activity intervention for knee replacement patients within an outpatient physical therapy facility.
- Trial name
- NCT03768206
- Testing
- Standard Physical Therapy, Physical therapist discuss aerobic physical activity, Physical activity session
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Parkinson's Disease
Exercise and Cognitive Training in Parkinson's Disease
This study compares the effects treadmill exercise, computerized cognitive training, or the combination of the two on executive function, dual-task performance, and performance on several Instrumental Activities of Daily Living…
- Trial name
- NCT01156714
- Testing
- Treadmill training with aerobic exercise, Memory training with computerized memory program, Combination of treadmill training and computerized memory
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- VA Office of Research and Development
Obesity-Related Malignant Neoplasm
Weight Loss Intervention for the Reduction of Cancer Risk and Health Disparities in Rural Ohio
This study determines the feasibility of a telephone-based weight lost intervention in reducing cancer risk and health disparities in rural Ohio.
- Trial name
- HERO (NCT05040152)
- Testing
- Dietary Counseling and Surveillance, Exercise Intervention, Informational Intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Mild Cognitive Impairment, Cognitive Decline
Exercise in Adults With Mild Memory Problems
This study evaluates the effects of physical exercise on cognition, functional status, brain atrophy and blood flow, and cerebrospinal fluid biomarkers of Alzheimer's disease in adults with a mild memory impairment.
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Memory Impairment
- Trial name
- EXERT (NCT02814526)
- Testing
- Aerobic exercise, Stretching/balance/range of motion exercise
- Where
- 14 sites in United States
- Volunteers
- 296 people
- Sponsor
- Alzheimer's Disease Cooperative Study (ADCS)
Migraine, Chronic Migraine
The Effect of Different Exercise Types on Migraine Frequency in Individuals With Migraine
The purpose of this study is to evaluate and compare the effect of different exercise types and combinations on migraine attacks in patients with migraine.
- Trial name
- NCT05568004
- Testing
- Combined exercise, Aerobic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ege University
Aging
Aerobic Exercise and Cerebrovascular Function
This proposal will evaluate two brain health measures, cerebrovascular perfusion and cerebrovascular reactivity (CVR), before and after a proven, interval-based, aerobic exercise intervention in older Veterans.
- Trial name
- NCT03803904
- Testing
- Spin
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alveolitis, Fibrosing, Fibrosis, Pulmonary
Sildenafil Study to Treat Idiopathic Pulmonary Fibrosis
Medicines that decrease blood pressure in the lungs may help idiopathic pulmonary fibrosis (IPF) patients function better. This study will test whether sildenafil improves the ability to exercise in patients with pulmonary…
- Conditions
- Alveolitis, Fibrosing, Fibrosis, Pulmonary, Hypertension, Pulmonary
- Trial name
- NCT00359736
- Testing
- sildenafil
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Degeneration; Articular Cartilage, Knee, Rheumatoid Arthritis
Comparison of Treatments Following Total Knee Replacement
Although total knee replacement (TKR) improves pain in numerous patients, it does not resolve many of the substantial functional limitations and physical inactivity that existed for a long time prior to the surgery.
- Conditions
- Degeneration; Articular Cartilage, Knee, Rheumatoid Arthritis, Osteoarthritis, Knee
- Trial name
- NCT02237911
- Testing
- Clinic-based outpatient exercise group, Community-based exercise group
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Pittsburgh
Stroke, Inflammation
Inflammatory Abnormalities in Muscle After Stroke: Effects of Exercise
The purpose of this study is to first define whether abnormalities of skeletal muscle are related to the presence of inflammation and to poor motor performance and whether this can be modified by exercise interventions.
- Trial name
- NCT00387712
- Testing
- Velocity based treadmill training, Duration based treadmill training
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- VA Office of Research and Development
Aging, Sleep Quality
Effects of Multi-component Exercise on Physical Performance and Sleep Quality in Older Adults
This quasi-experimental study evaluated the effects of an 8-week multi-component group exercise program on physical performance and sleep quality among community-dwelling older adults in Taiwan.
- Conditions
- Aging, Sleep Quality, Physical Performance
- Trial name
- NCT07598123
- Testing
- Multi-component Group Exercise Program
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tunghai University
Brain Injury, Concussion
Sub-Threshold Exercise Treatment for Adolescents With Sports Related Concussion
Adolescents with concussion will be randomly assigned to a treatment group where they will receive sub-threshold exercise, or assigned to a placebo group where they will receive structured stretching exercises.
- Trial name
- NCT02710123
- Testing
- Sub-Threshold exercise prescription, Structured stretching prescription
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- University at Buffalo
Traumatic Brain Injury
Translational Research Examining Acupuncture Treatment in Traumatic Brain Injury
The purpose of this study is to examine the effects of acupuncture on cerebral blood flow (CBF) and blood biomarkers during the acute 10-day window following traumatic brain injury, to determine if those changes correlate with…
- Trial name
- TREAT-TBI (NCT02623218)
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- AOMA Graduate School of Integrative Medicine
COPD
COPD Access to Pulmonary Rehabilitation Intervention
Persons with COPD have significant functional disability but cannot access rehabilitative treatment at hospital-based conventional pulmonary rehabilitation (PR) programs.
- Trial name
- CAPRI (NCT03794921)
- Testing
- Every Step Counts
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases
Impact of Statin Therapy on Adaptations to Aerobic Exercise
The purpose of this study is to determine how different doses of a statin affect muscle health and exercise.
- Trial name
- NCT03360916
- Testing
- Lipitor 20Mg Tablet, Lipitor 80Mg Tablet, Exercise Program
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center