Clinical trials: Amlodipine
Essential Hypertension
PMS Study of Amlodipine/Valsartan for the Treatment of Hypertension
The antihypertensive effect of Amlodipine/Valsartan combination has been evaluated in worldwide populations including Asian patients.
- Trial name
- NCT02058446
- Testing
- Amlodipine/Valsartan
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- TSH Biopharm Corporation Limited
Healthy
Bioequivalency Study of Amlodipine Besylate Tablets, 10 mg of Dr. Reddy's Under Fasting Conditions
The purpose of this study is to determine the pharmacokinetics and bioequivalence of amlodipine besylate formulations under fasting conditions.
- Trial name
- NCT01131923
- Testing
- Amlodipine
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Hypertension, Hyperlipidemia
Clinical Trial of Temisartan/Amlodipine & Rosuvastatin in Subjects With Hypertension and Hyperlipidemia
Randomized, double-blind, active-controlled, multicenter phase 3 trial to evaluate efficacy and safety of co-administrated temisartan/amlodipine and rosuvastatin in subjects with hypertension and hyperlipidemia.
- Trial name
- NCT03067688
- Testing
- Temisartan+Amlodipine+Rosuvastatin (Combination drug), Temisartan+Amlodipine, Temisartan+Rosuvastatin
- Where
- South Korea
- Volunteers
- 202 people
- Sponsor
- Yuhan Corporation
Essential Hypertension, Hypercholesterolemia
Effect of Atorvastatin on Carotid Intima Media Thickness
The investigators hypothesize that additive effects of combined antihypertensive medications and statin in a single pill combination may better reduce progression of vascular remodeling and inhibit atherosclerosis progression.
- Trial name
- NCT04306627
- Testing
- Perindopril/Amlodipine and Perindopril/Amlodipine/Atorvastatin treatment
- Volunteers
- 200 people
- Sponsor
- Yerevan State Medical University
Stroke, Cognitive Decline
Polypill and RiscOMeter to Prevent StrOke and CogniTive ImpairmEnt (PROMOTE)
This study is a phase III, prospective, placebo-controlled randomized clinical trial involving 8,518 subjects with low to moderate stroke risk, followed for 3 years in Brazil.
- Trial name
- PROMOTE (NCT05155137)
- Testing
- Drug Capsule (Valsartan + Amlodipine + Rosuvastatin), Stroke Riskometer
- Where
- 2 sites in Brazil
- Volunteers
- 8,518 people
- Sponsor
- Hospital Moinhos de Vento
Hypertension and Cardiovascular Risk Factors
Real Life Experience With Caduet In Patients With Cardiovascular Risk Factors
To assess the effect of single pill therapy on the management of hypertension and other cardiovascular risk factors (e.g., dyslipidemia) in Indian patients in whom the treating doctor has already considered that the…
- Trial name
- EXCEL (NCT00579254)
- Testing
- CADUET (AMLODIPINE 5 mg/ATORVASTATIN 10 mg or 20 mg)
- Volunteers
- 112 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Hypertension
Aliskiren Study of Safety and Efficacy in Senior Hypertensives
This study is designed to compare the blood pressure lowering efficacy of aliskiren, a combination of aliskiren plus amlodipine, and ramipril in elderly patients with mild to moderate hypertension.
- Trial name
- ASSESS (NCT01922141)
- Testing
- Aliskiren, Amlodipine, Ramipril
- Sponsor
- Novartis Pharmaceuticals
Diabetes Mellitus, Arterial Hypertension
Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management Strategy
The aim of this study is to to analyze if it is possible to reach the goals of HbA1c <7.0% and blood pressure <= 130/80 mm Hg in a cohort of patients with type 2 diabetes attending a primary care unit, using ony those resources…
- Trial name
- NCT00935805
- Testing
- Metformin, Glybenclamide, NPH insulin
- Where
- Brazil
- Volunteers
- 124 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hypertension
Interaction Between Antihypertensives and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
NSAIDs may increase blood pressure and blunt the effects of many antihypertensives. Members of these drug classes differ in their propensity to such an interaction.
- Trial name
- NCT00631514
- Testing
- acetaminophen, ibuprofen, piroxicam
- Where
- Croatia
- Volunteers
- 88 people
- Sponsor
- University of Split
Diabetes Mellitus, High Blood Pressure
Optimal Blood Pressure for the prevenTIon of Major vAscuLar Events in Patients With DIABETES Mellitus (OPTIMAL-DIABETES)
High blood pressure (BP) is a major public health concern, especially in low and middle income countries. High BP is a highly prevalent condition, and it is usually associated with diabetes mellitus.
- Conditions
- Diabetes Mellitus, High Blood Pressure, Cardiovascular Diseases, Cognitive Impairment
- Trial name
- NCT04040634
- Testing
- Intensive Control of Systolic Blood Pressure (SBP), Standard control of Systolic Blood Pressure (SBP)
- Where
- 32 sites in Brazil
- Volunteers
- 9,476 people
- Sponsor
- Hospital Israelita Albert Einstein
Hypertension
Efficacy and Safety Study of S-Amlodipine Gentisate Compared to Amlodipine Besylate to Treat Mild-to-Moderate Hypertension
The goal of this study is to compare the antihypertensive effect and tolerability of S-amlodipine gentisate with those of amlodipine besylate in patients with mild to moderate hypertension.
- Trial name
- NCT00289406
- Testing
- S-amlodipine gentisate, Amlodipine besylate
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- SK Chemicals Co., Ltd.
Proteinuria
An Extension Study Designed to Assess Effects of Losartan on Proteinuria in Pediatric Populations (MK-0954-326 AM1,EXT1(AM2))
The purpose of this study is to evaluate the effects of losartan on proteinuria in pediatric patients.
- Trial name
- NCT00568178
- Testing
- Losartan Potassium, Comparator: amlodipine besylate
- Volunteers
- 306 people
- Sponsor
- Organon and Co
Hypertension
A Clinical Study to Compare Combination of Aliskiren+ HCTZ to Irbesartan+ HCTZ or Amlodipine+ HCTZ or HCTZ Alone in Obese Hypertensive Not Responsive to HCTZ 25 mg
To evaluate the blood pressure lowering effects of the combination of aliskiren 300 mg and HCTZ 25 mg in obese patients with essential hypertension inadequately treated with HCTZ 25 mg, compared to irbesartan or amlodipine with…
- Trial name
- NCT00219115
- Testing
- aliskiren
- Where
- 2 sites in United States, Germany
- Volunteers
- 493 people
- Sponsor
- Novartis
Essential Hypertension
Clinical Efficacy and Safety Evaluation of Irbesartan High and Amlodipine Combined Therapy in Essential Hypertension Patients
The purpose of this study is to evaluate efficacy and safety of Irbesartan and Amlodipine combined therapy in patients with essential hypertension inadequately controlled on Irbesartan monotherapy
- Trial name
- NCT05475665
- Testing
- Irbesartan/Amlodipine, Irbesartan
- Where
- South Korea
- Volunteers
- 157 people
- Sponsor
- Handok Inc.
Essential Hypertension
A Long-term (12 Months) Safety, Tolerability and Efficacy Study of LCZ696 in Patients With Essential Hypertension
The purpose of this study is to assess the long-term safety, tolerability and efficacy of LCZ696.
- Trial name
- NCT01256411
- Testing
- LCZ696, Amlodipine, Hydrochlorothiazide (HCTZ)
- Where
- 33 sites in China, Japan and 3 more
- Volunteers
- 341 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension
CKD-330 Drug-Drug Interaction Study (Candesartan)
The purpose of this study is to evaluate a pharmacokinetic drug interaction and safety of Candesartan between free combination of Candesartan and Amlodipine and Candesartan monotherapy.
- Trial name
- CKD-330(C) (NCT02064621)
- Testing
- Candesartan 32mg, Candesartan 32mg/Amlodipine 10mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Hypertension
Blood Pressure Lowering Ability and Safety of an Olmesartan and Amlodipine Based Treatment Regimen in Patients With Stage I and Stage II Hypertension
This study will be conducted to assess the efficacy and safety of an amlodipine/olmesartan treatment regimen in stage 1 and stage 2 hypertensive subjects.
- Trial name
- NCT00527514
- Testing
- Amlodipine, Olmesartan medoxomil plus amlodipine
- Where
- 18 sites in United States
- Volunteers
- 185 people
- Sponsor
- Daiichi Sankyo
Arterial Hypertension, Dyslipidemias
Fixed Combination for Lipid and Blood Pressure Control
The aim of this study is to compare the effect of fixed and free combination of atorvastatin/perindopril/amlodipine on blood pressure and lipid levels.
- Conditions
- Arterial Hypertension, Dyslipidemias, Blood Pressure, Lipid Metabolism Disorders
- Trial name
- FILIP (NCT03047538)
- Testing
- Atorvastatin, Amlodipine, Perindopril
- Where
- Czechia
- Sponsor
- Charles University, Czech Republic
Healthy
A Randomized, Open-label, Single Dose, Two-way Crossover Clinical Trial to Compare the Safety, Pharmacokinetic Profiles of UI15AML055MT and Amosartan® Tablet 5/50 mg After a Single Oral Administration in Healthy Male Volunteers
A randomized, open-label, single dose, two-way crossover clinical trial to compare the safety, pharmacokinetic profiles of UI15AML055MT and Amosartan® tablet 5/50 mg after a single oral administration in healthy male volunteers
- Trial name
- UI15AML055MT (NCT02166398)
- Testing
- UI15AML055MT, Amosartan 5/50
- Where
- South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Korea United Pharm. Inc.
Healthy Male Volunteer
The Pharmacokinetic Drug-drug Interaction and Safety of Telmisartan/Amlodipine and Rosuvastatin in Healthy Male Volunteers
To investigate the pharmacokinetic Drug-drug interaction
- Trial name
- NCT02233218
- Testing
- Telmisartan, Amlodipine, Rosuvastatin
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation