Clinical trials: Amlodipine
Blood Pressure
Effect of Active Telephone Calls in the Compliance of Hypertensive Patients With Treatment
The purpose of this study is to evaluate the importance of providing guidelines to patients via active telephone calls in blood pressure control and in the discontinuation of treatment among hypertensive patients.
- Trial name
- NCT00813722
- Testing
- phone call, amlodipine (calcium chanel blocker) and losartan (at1 antagonist), atenolol (beta blocker) and hydrochlorothiazide (diuretic)
- Where
- 2 sites in Brazil
- Volunteers
- 400 people
- Sponsor
- University of Sao Paulo
Hypertensive Nephrosclerosis, Chronic Renal Insufficiency
African American Study of Kidney Disease and Hypertension
The AASK is a multicenter, randomized, controlled clinical trial using a 2 × 3 factorial design to evaluate the effects of level of blood pressure control and type of anti-hypertensive medication on progression of chronic renal…
- Trial name
- AASK (NCT04364139)
- Testing
- MAP goal less than or equal to 92 mm Hg, MAP goal 102-107 mm Hg, Ramipril
- Volunteers
- 1,094 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Hypertension, Dyslipidemia
An Observational Study to Evaluate Effectiveness and Safety of Amosartan Q Tablet
This study was to evaluate the therapeutic effect and safety of amosartan Q tablet administration in adult patients with hypertension and dyslipidemia.
- Trial name
- NCT05450575
- Testing
- Amosartan Q tablet
- Where
- South Korea
- Volunteers
- 5,400 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Hypertension, Hyperlipidemia
PK Study of YH22189 FDC Compared to Combination of Telmisartan/Amlodipine and Rosuvastatin
This is a Randomized, open-label, single-dose, 3-treatment, 3-period, 3-sequence crossover design.
- Trial name
- NCT02608242
- Testing
- YH22189, Twynsta 80/10mg, Crestor 20mg
- Where
- South Korea
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
Depression
Vascular Augmentation of Late-life Unremitted Depression (VALUeD)
Depression has a high occurrence and causes other problems in older people, two thirds of these patients will not have a lessening in their condition from routine treatment medication.
- Trial name
- VALUeD (NCT01557153)
- Testing
- Amlodipine
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Gateshead Health NHS Foundation Trust
Hypertension
Efficacy and Safety of a Therapy Change From Candesartan 32 mg to Fixed Combination of Olmesartan 40 mg/Amlodipine 10 mg
The investigators want to find out if a treatment with a new combination of two different antihypertensive drugs (olmesartan and amlodipine) in one tablet in patients with moderately elevated blood pressure is more effective than…
- Trial name
- Sevicontrol-2 (NCT01611077)
- Testing
- Candesartan cilexetil, Olmesartan medoxomil, Olmesartan/amlodipine
- Where
- 11 sites in Germany
- Volunteers
- 88 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Healthy
Amlodipine-Benazepril 10mg-20mg Capsules in Healthy Subjects Under Fasting Conditions
The objective of this study is to compare the rate and extent of absorption of amlodipine-benzazepril 10 mg-20 mg capsules (test) versus Lotrel® (reference), administered as 1 x 10 mg capsule under fasting conditions.
- Trial name
- NCT00834977
- Testing
- Amlodipine-benazepril 10 mg-20 mg capsules, Lotrel® 10 mg-20 mg capsule
- Where
- 2 sites in Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Hypertension
Losartan/Amlodipine on Hemodynamics Parameters and Arterial Stiffness in Arterial Hypertension
Systemic Arterial Hypertension (SAH) is a disease with a high prevalence in Mexico and worldwide. SAH is associated with an increase in cardiovascular morbidity and mortality, causing cardiovascular disease (CVD), heart failure…
- Trial name
- NCT03626259
- Testing
- Losartan and Amlodipine, Losartan
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Hypertension
Study to Evaluate the Efficacy and Safety of Combination Aliskiren/Amlodipine in Patients Not Adequately Responding to Aliskiren Alone
This study will assess the safety and efficacy of combination aliskiren/amlodipine in patients not adequately controlled with aliskiren alone
- Trial name
- NCT00777946
- Testing
- Aliskiren 300 mg, Aliskiren/Amlodipine 300/5 mg, Aliskiren/Amlodipine 300/10 mg
- Where
- 9 sites in Estonia, France and 7 more
- Volunteers
- 818 people
- Sponsor
- Novartis
Hypertension
One Year Study to Evaluate the Safety of the Combination of Valsartan and Amlodipine in Patients With Hypertension
A ONE YEAR SAFETY STUDY FOR PATIENTS WHO COMPLETE STUDY VAA489A2201.
- Trial name
- NCT00409851
- Testing
- valsartan+amlodipine
- Where
- 2 sites in United States, Germany
- Volunteers
- 1,293 people
- Sponsor
- Novartis
Hypertension
DMTA07 Combine With Amlodipine Treatment in Patients With Hypertension
The purpose of this study is to compare the different dose of DMTA07 (DM) combine with amlodipine in the treatment of mild to moderate essential hypertension, and to define the optimized dose of DM in the combination therapy.
- Trial name
- NCT01614366
- Testing
- AM 5 + DM 0, AM 5 + DM 2.5, AM 5 + DM 7.5
- Where
- 8 sites in Taiwan
- Volunteers
- 111 people
- Sponsor
- TSH Biopharm Corporation Limited
Hypertension
Efficacy and Safety of a Single-pill Fixed Combination of Sufficient Losartan/Hydrochlorothiazide in Chinese Hypertensive Patients
1. Study name: Efficacy and safety of a single-pill fixed combination of sufficient losartan/hydrochlorothiazide in Chinese hypertensive patients (FOCUS) 2.
- Trial name
- NCT03946514
- Testing
- losartan/hydrochlorothiazide, amlodipine/hydrochlorothiazide
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Hypertension
Italian Study on the Cardiovascular Effects of Systolic Blood Pressure Control - CARDIOSIS Study
Multicenter, prospective, randomised, open study comparing the effect of the following two strategies in hypertensive subjects > 55 years and poorly controlled (systolic blood pressure >= 150 mmHg) by antihypertensive treatment…
- Trial name
- NCT00421863
- Testing
- Triatec 10 mg, Triatec HCT 5, Lasix 25
- Where
- 45 sites in Italy
- Volunteers
- 1,111 people
- Sponsor
- Heart Care Foundation
Hypertension With Dyslipidemia
The PK Characteristics of the Co-administration of Rosuvastatin and Telmisartan/Amlodipine and JLP-1401 in Healthy Adult Volunteers Volunteers
The PK Characteristics of the Co-administration of Rosuvastatin and Telmisartan/Amlodipine and JLP-1401 in Healthy Adult Volunteers.
- Trial name
- NCT03707899
- Testing
- JLP-1401, Telmisartan/Amlodipine, Rosuvastatin
- Where
- South Korea
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Cardiovascular Diseases, Heart Diseases
Genetics of Hypertension Associated Treatments (GenHAT)
To examine whether the association between selected hypertensive genes and combined fatal coronary heart disease and nonfatal myocardial infarction in high-risk hypertensives is modified by the type of antihypertensive treatment…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Coronary Disease
- Trial name
- GenHAT (NCT00006294)
- Testing
- Chlorthalidone, Lisinopril, Amlodipine
- Where
- United States
- Volunteers
- 37,939 people
- Sponsor
- Donna Arnett, 257-5678
Healthy Male Subjects
Clinical Trial to Assess the Pharmacokinetic Characteristics of Lodivixx Tab. 5/160mg in Healthy Male Subjects (N=60)
To assess the pharmacokinetic characteristics of valsartan and S-amlodipine after single oral administration of Exforge tab. 10/160mg, a combination formulation of valsartan and amlodipine as reference drug and Lodivixx tab
- Trial name
- NCT01819779
- Testing
- Exforge tab. 10/160mg, Lodivixx tab. 5/160mg
- Where
- South Korea
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Hanlim Pharm. Co., Ltd.
Cardiovascular Diseases, Heart Diseases
Treatment of Mild Hypertension Study (TOMHS)
To compare the effects of nonpharmacologic therapy alone with those of one of five active drug regimens combined with non-pharmacologic therapy, for long- term management of patients with mild hypertension.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Vascular Diseases
- Trial name
- NCT00000522
- Testing
- diet, sodium-restricted, diet, reducing, exercise
- Sponsor
- University of Minnesota
Hypertension,Essential
Determining the Optimal Dose of AD-209 in Patients With Essential Hypertension
The purpose of this study is to determine the optimal dose of AD-209 in patients with Essential Hypertension.
- Trial name
- NCT04218552
- Testing
- AD209, Amlodipine low, Amlodipine high
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Addpharma Inc.
Hypertension
Skin Sodium and Salt Sensitivity of Blood Pressure
Eating too much salt raises blood pressure and the risk of having a heart attack or stroke. The investigators do not fully understand why salt raises blood pressure, but storage of sodium in the body, particularly in the skin…
- Trial name
- INTREPID (NCT05976438)
- Testing
- Amlodipine, Chlortalidone
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Hypertension
Telmisartan, Amlodipine and Flow Mediated Dilation
To show superior effects of the combination Telmisartan and Amlodipine (T and A) vs Olmesartan and Hydrochlorothiazide (O and HCTZ) on endothelial dysfunction as measured by flow mediated dilation (FMD) in hypertensive at risk…
- Trial name
- TEAMSTAprotect (NCT01180205)
- Testing
- Telmisartan, Amlodipine, Olmesartan medoxomil
- Where
- Germany
- Volunteers
- 576 people
- Sponsor
- Johannes Gutenberg University Mainz