Clinical trials: Amoxicillin
Helicobacter Pylori Infection
Tailored Therapy for Helicobacter Pylori in Children
This study is designed to compare the eradication rates，safety and compliance of tailored therapy to those of standard triple therapy in children with H. pylori infection.
- Trial name
- NCT02635191
- Testing
- Tailored Group, Standard group
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Children's Hospital
Aggressive Periodontitis
Efficacy of Three Antibiotic Protocols for Aggressive Periodontitis Treatment
The aim of the present study is to evaluate the clinical and microbiological efficacy of moxifloxacin or amoxicillin plus metronidazole in one-stage scaling and root planing in treating generalized aggressive periodontitis.
- Trial name
- NCT02839421
- Testing
- Scaling and Root Planing combined with moxifloxacin
- Where
- Colombia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Facultad Nacional de Salud Publica
Urinary Tract Infection in Pregnancy
Lactobacillus Reuteri for Treatment of Uncomplicated UTI in Pregnant Women
Prevalence of uro-genital infections during pregnancy move between 7% to 12% in developed countries, meanwhile in developing countries this figure moved between 14% and until 55%, such is the case of Mexico.
- Trial name
- UTIPregnant (NCT03362697)
- Testing
- Probiotics, Antibiotics
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Innovacion y Desarrollo de Estrategias en Salud
Kerosene Pneumonitis
Antibiotic Efficacy in Pneumonitis Following Paraffin (Kerosene) Ingestion in Children
Paraffin (kerosene) ingestion in the developing world accounts for a large number of visits to healthcare facilities, especially amongst children.
- Trial name
- NCT01253980
- Testing
- Amoxicillin
- Where
- South Africa
- Volunteers
- 74 people
- Sponsor
- University of Cape Town
Acute Cholecystitis
Extended Antibiotic Therapy in Postoperative of Laparoscopic Cholecystectomy in Acute Cholecystitis
Acute cholecystitis (AC) is a very common complication of cholelithiasis, encountered in 20% of symptomatic patients. Nowadays laparoscopic cholecystectomy (LC) is the standard treatment in mild and moderates forms of diseases…
- Trial name
- NCT02057679
- Testing
- Amoxicillin clavulanic
- Where
- Argentina
- Volunteers
- 200 people
- Sponsor
- Hospital Italiano de Buenos Aires
Surgical Site Infection
Benefit of a Single Preoperative Dose of Antibiotics for the Prevention of Surgical Site Infections
In a rural hospital in Tanzania the rate of surgical site infections (SSI) was 21.6%. Inappropriate choice of antibiotics and of administration time were determined as sole risk factors in this setting.
- Trial name
- SSI2 (NCT00801099)
- Testing
- Amoxicillin/Clavulanic Acid
- Where
- Switzerland
- Volunteers
- 276 people
- Sponsor
- Swiss Tropical & Public Health Institute
Immune Thrombocytopenic Purpura
Helicobacter Pylori Immune Thrombocytopenic Purpura
We designed a study for evaluate the efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenic purpura (ITP) patients with moderate thrombocytopenia.
- Trial name
- HpyloriITP (NCT01255332)
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Cooperative Study Group A for Hematology
Precancerous Gastric Lesions
A Randomized Multi-Intervention Trial to Inhibit Precancerous Gastric Lesions in Lingu, Shandong Province
The Division of Cancer Epidemiology and Genetics is conducting a collaborative randomized multi-intervention trial with the Beijing Institute for Cancer Research to evaluate the etiologic role of Helicobacter pylori, garlic, and…
- Trial name
- NCT00339768
- Testing
- Amoxicillin/omeprazole
- Where
- China
- Volunteers
- 3,411 people
- Sponsor
- National Cancer Institute (NCI)
Human Gut Microbiota
Effects of Pre-, Pro- & Anti-biotics on Gut Microbiota
The purpose of this study is to compare and contrast the effects of a prebiotic (Trametes Versicolor), a probiotic (Saccharomyces boulardii) and an antibiotic (amoxicillin) on the gut microbiota of healthy volunteers.
- Trial name
- NCT01414010
- Testing
- Trametes versicolor extract, Saccharomyces boulardii, Amoxicillin
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Esophagus Disorder, Esophageal Achalasia
Impact of Antibiotic Prophylaxis in Per-oral Endoscopic Myotomy for Esophageal Motor Disorders
No recommendation regarding antibiotic prophylaxis and preparation modalities are available for patients with esophageal motor disorders who benefit from Per-Oral Endoscopic Myotomy (POEM).
- Trial name
- NCT03944863
- Testing
- Antibiotics
- Volunteers
- 252 people
- Sponsor
- Société Française d'Endoscopie Digestive
HELICOBACTER PYLORI INFECTIONS
Fecal Molecular Susceptibility-guided Hp First-line Therapy
The goal of this clinical trial is to evaluate the eradication efficacy and health economic benefits of individualized regimens guided by fecal molecular susceptibility testing with 7-day and 14-day courses in the first-line…
- Trial name
- NCT07405684
- Testing
- 7-day fecal molecular susceptibility-guided therapy, 14-day fecal molecular susceptibility-guided therapy
- Where
- 4 sites in China
- Volunteers
- 544 people
- Sponsor
- Shanghai Zhongshan Hospital
Helicobacter Pylori Infection
Doxycycline- and Furazolidone-containing Quadruple Regimen is Superior of Tailored Therapy
Doxycycline- and Furazolidone-containing Quadruple Regimen can be a successful rescue treatment for Helicobacter pylori Infection patients after Failure of several therapy.
- Trial name
- NCT02894268
- Testing
- Doxycycline, Furazolidone, Esomeprazole
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sir Run Run Shaw Hospital
Aggressive Periodontitis
Doxycycline in the Treatment of Aggressive Periodontitis
The aim of the study was to compare the clinical effects of systemic use of doxycycline to amoxicillin plus metronidazole as adjunctive treatment in nonsurgical debridement of aggressive periodontitis (AgP).
- Trial name
- NCT03727620
- Testing
- amoxicillin plus metronidazole, Doxycycline
- Where
- Morocco
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohammed V Souissi University
Microbial Colonization
Effect of Antibiotics on Gut Microbiome and Plasma Metabolome
In recent years it has been observed that the gut microbiome can produce metabolites into systemic circulation and thus have important health effects even outside the gastrointestinal system.
- Trial name
- NCT03273296
- Testing
- Amoxicillin, Azithromycin, Vancomycin
- Where
- Finland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Pneumonia, Community-Acquired, Bacterial Pneumonia
Efficacy and Safety of Faropenem in Bangladeshi Adult Patients With Community-Acquired Bacterial Pneumonia (CABP)
The goal of this clinical trial is to evaluate the efficacy and safety of faropenem in comparison to co-amoxiclav and clarithromycin in Bangladeshi adults diagnosed with community-acquired bacterial pneumonia (CABP).
- Trial name
- NCT06804096
- Testing
- Faropenem, Co-amoxiclav, Clarithromycin 500 mg
- Where
- 2 sites in Bangladesh
- Volunteers
- 129 people
- Sponsor
- Dr. Md. Alimur Reza
Helicobacter Pylori
A Study of Vonoprazan in Adults With Helicobacter Pylori
Helicobacter Pylori (H Pylori) is a bug found in the digestive system. It can cause soreness and redness in the stomach (gastritis). It can also cause ulcers in the stomach and other parts of the digestive system.
- Trial name
- NCT04753437
- Testing
- Clarithromycin, Amoxicillin, Bismuth potassium citrate
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Takeda
Periodontitis, Periodontal Diseases
Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers
The purpose of this study is to determine in current and non-smokers the clinical and microbiological effects of 3 therapies: scaling and root planing (SRP) alone; SRP in combination with the orally administered antibiotic…
- Trial name
- NCT00066066
- Testing
- Scaling and root planing, Metronidazole, Amoxicillin
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- The Forsyth Institute
HELICOBACTER PYLORI INFECTIONS
Efficacy and Safety of 7-day Triple Therapy Containing Amoxicillin and Tetracycline Versus 14-day Dual Therapy for Helicobacter Pylori Eradication
With the increasing prevalence of antibiotic resistance, the clinical efficacy of conventional 7-day triple therapy for Helicobacter pylori eradication has been substantially diminished.
- Trial name
- PSM (NCT07333001)
- Testing
- 7-day triple therapy, 14-day dual therapy
- Where
- China
- Volunteers
- 508 people
- Sponsor
- Yueyue Li
Endocarditis, Infective
Ampicillin and Ceftriaxone for the Treatment of Enterococcus Faecalis Infective Endocarditis.
Phase IV, open-label, randomized and multicenter clinical trial to prove that patients with Enterococcus faecalis infective endocarditis treated with an antibiotic treatment as a continuous infusion is non-inferior to the…
- Trial name
- DOBLEI (NCT06423898)
- Testing
- Ampicillin plus ceftriaxone in continuous infusion, Ampicillin plus ceftriaxone in intermittent infusion of 14 days, after which the treatment may be changed
- Where
- 18 sites in Spain
- Volunteers
- 284 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Acute Appendicitis
Patient Choice Between Antibiotics and Appendectomy in Uncomplicated Appendicitis (FRENCH 47 - ALACARTE)
The ALACARTE study evaluates a strategy in which patients with acute uncomplicated appendicitis are given the choice between appendectomy and antibiotic therapy alone.
- Trial name
- ALACARTE (NCT07857252)
- Testing
- Shared decision-making, amoxicillin-clavulanate, Appendectomy
- Where
- France
- Volunteers
- 560 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris