Clinical trials: Amoxicillin, completed
Sinusitis
Oral Steroids in Chronic Rhinosinusitis Without Nasal Polyps
Chronic rhinosinusitis is a common disease that effects millions of people world wide. Despite its frequency it is unclear what treatment options are the best for these patients.
- Trial name
- NCT02927834
- Testing
- 6 day Prednisone, Augmentin, 21 day Prednisone
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Loma Linda University
Helicobacter Pylori Infection
High Dose of Amoxicillin and Metronidazole Plus Bismuth For Helicobacter Pylori Treatment
Amoxicillin and metronidazole （400mg Q.D.S） based quadruple therapy had achieved a high cure rate in the rescue treatment of helicobacter pylori infection.
- Trial name
- NCT03557437
- Testing
- Esomeprazole, Amoxicillin, Metronidazole, Bismuth Potassium Citrate
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Infectious Diseases
A Study to Assess Efficacy and Safety of IV/PO Moxifloxacin in the Treatment of cSSSIs
The purpose of this study is to assess if a therapy with intravenous and oral moxifloxacin is as effective as a therapy with intravenous and oral amoxicilline/clavulanate in the treatment of complicated skin and skin structure…
- Trial name
- MERAK (NCT00828971)
- Testing
- Avelox (Moxifloxacin, BAY12-8039), Amoxicilline/clavulanic
- Where
- 22 sites in Italy
- Volunteers
- 16 people
- Sponsor
- Bayer
Beta-lactam Antibiotics, Therapeutic Drug Monitoring
The OPTIMAL TDM Study: Determining Optimal Beta-lactam Plasma Concentrations Through Therapeutic Drug Monitoring
Little is known of beta-lactam antibiotics' true therapeutic plasma concentration range. The aims of this study are to define evidence-based, safe and effective upper and lower limits of the plasma concentrations of imipenem…
- Conditions
- Beta-lactam Antibiotics, Therapeutic Drug Monitoring, Toxicity, Efficacy
- Trial name
- OPTIMAL TDM (NCT03790631)
- Testing
- The study is observational.
- Where
- Switzerland
- Volunteers
- 771 people
- Sponsor
- University of Geneva, Switzerland
Helicobacter Pylori Infection
Dual Therapy With Vonoprazan Plus Amoxicillin or Doxycycline Versus Bismuth Quadruple Therapy for Helicobacter Pylori Eradication.
It is planned to select Hp infection patients in a number of tertiary hospitals in Jiangsu and randomly divide them into three groups: group A is the classic group, receiving Vonoprazan 20mg, bid + amoxicillin 1.0g, bid +…
- Trial name
- NCT06412588
- Testing
- Vonoprazan+amoxicillin+doxycycline+bismuth for 14 days, Vonoprazan+Amoxicillin, Vonoprazan+doxycycline
- Where
- China
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Helicobacter Pylori Infection
Sequential and Hybrid Therapies for H Pylori Infection
Primary: To evaluate efficacy of 14 day 2-phase sequential therapy given in two forms. One in which the first component consists of a proton pump inhibitor and amoxicillin given for 7 days followed by the PPI, clarithromycin and…
- Trial name
- NCT01085786
- Testing
- 14-day sequential treatment, 14-day hybrid treatment
- Where
- 2 sites in Taiwan
- Volunteers
- 240 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Aggressive Periodontitis
Two Different Antibiotic Agents to Treat Generalized Aggressive Periodontitis
The aim of this study is to assess the clinical outcomes of full-mouth ultrasonic debridement combined with clarithromycin or amoxicillin + metronidazole association for the treatment of generalized aggressive periodontitis…
- Trial name
- NCT02969928
- Testing
- Full-mouth ultrasonic debridement, Clarithromycin, Amoxicillin
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Vaginitis Gardnerella
Treatment of Gardnerella Vaginalis Vaginal Colonization With Amoxicillin
This is a randomized, double-blind, placebo-controlled Phase 2 study designed to determine if amoxicillin will eradicate vaginal colonization/infection with Gardnerella vaginalis (GV) when administered to women who are…
- Trial name
- NCT03211156
- Testing
- Amoxicillin
- Where
- 2 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Infective Endocarditis
Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Streptococcus
Infective endocarditis (IE) is a serious infection with a significant burden for patients and hospitals (in France, median length of hospital stay = 43 days), partly due to the long duration of intravenous (IV) antibacterial…
- Trial name
- NCT02701595
- Testing
- Amoxicillin, Conventional IV treatment of streptococci/enterococci IE following European guidelines 2015 including amoxicillin, gentamicin, amicillin, vancomycin, penicillin G, ceftriaxone, netilmicin
- Where
- 45 sites in France
- Volunteers
- 324 people
- Sponsor
- University Hospital, Tours
Helicobacter Pylori Infection
Comparison of Two Rescue Therapies for Helicobacter Pylori Infection
From the profiles of antibiotic susceptibility data following eradication therapy, tetracycline, amoxicillin and levofloxacin are all good candidates of antibiotics used in the rescue treatment.
- Trial name
- NCT02547012
- Testing
- esomeprazole+amox+levo+tetra, esomeprazole+amox+levo
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Third Molar Surgery
Is Therapeutic Elastic Bandage As Effective As Corticosteroids Following Third Molar Surgery?
In this study; Among the patients randomized because of severe postoperative sequelae expected as a result of radiological and clinical examinations; nonsteroid antiinflammatory drug prescribed group compared with preoperative…
- Trial name
- NCT04200885
- Testing
- Dexketoprofen Trometamol, Dexamethasone 21-Phosphate, Therapeutic Elastic Bandage
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Sinusitis
Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis
The purpose of this study is to determine the best duration(3 versus 6 weeks) of antibiotics as part of maximal medical therapy for treating chronic sinusitis and thus preventing patients from having to have sinus surgery.
- Trial name
- NCT01825408
- Testing
- Doxycycline, Azithromycin, Augmentin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Periodontitis, Clinical and Microbiological Effects
Effects of the Variation in the Time of Systemic Administration of Metronidazole and Amoxicillin Associated to the Non-surgical Therapy of Chronic Periodontitis.
Background: Peridontitis is a group of diseases with complex bacterial etiology that affects a large proportion of the Chilean and worldwide population.
- Trial name
- Metro + Amoxi (NCT01211223)
- Testing
- Administration of Metronidazole plus Amoxicillin
- Where
- Chile
- Volunteers
- 42 people
- Sponsor
- University of Chile
Helicobacter Pylori Infection, Chronic Gastritis
Study on The Efficacy and Safety of Vonoprazan-containing Berberine Triple Therapy in Helicobacter Pylori First-Line Eradication
The purpose of this study was to evaluate the efficacy and safety of the triple therapy of berberine hydrochloride, vonorasan and amoxicillin for the primary eradication of Helicobacter pylori.It is hypothesized that berberine…
- Trial name
- NCT06514274
- Testing
- Berberine, Vonoprazan, Amoxicillin
- Where
- China
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Drug Resistant Malaria Due to Plasmodium Falciparum
Antimalaria Drugs Susceptibility Testing for an Effective Management of Infected Patients in Sub-Sahara Africa
The antimalarial drugs efficacy and safety study will be conducted in the Clinics and hospital of the Cameroon Development Corporation (CDC) Estates, Tiko Health District, located in a typical forest and rainfall area in the…
- Trial name
- NCT02974348
- Testing
- Arthemeter-lumefantrine, Artesunate mefloquine, Dihydroartemisinin piperaquine
- Where
- Cameroon
- Volunteers
- 300 people
- Sponsor
- University of Bamenda
Perforated Appendicitis
Role of Intravenous Versus Home Oral Antibiotics in Perforated Appendicitis
To compare the effect of a single-agent home intravenous (IV) versus oral antibiotic therapy on complication rates and resource utilization following appendectomy for perforated appendicitis
- Trial name
- NCT02724410
- Testing
- home intravenous ertapenem, home oral amoxicillin-clavulanate, peripheral inserted central Catheter
- Volunteers
- 82 people
- Sponsor
- Wake Forest University Health Sciences
Upper Respiratory Tract Infections
LiveSpo Navax® Supports the Treatment of Acute Rhinosinusitis and Otitis Media
Acute respiratory tract infections (ARTIs), such as acute rhinosinusitis (ARS) and acute otitis media (AOM), are common worldwide and caused by viruses or bacteria entering the body through the mouth and nose.
- Trial name
- NCT05804123
- Testing
- 0.9% NaCl physiological saline Nasal-spraying, LiveSpo Navax®, Augmentin 500Mg Tablet
- Where
- Vietnam
- Volunteers
- 175 people
- Sponsor
- Anabio R&D
Periodontitis, Periodontal Pocket
Efficacy of Amoxicillin-metronidazole Compared to Clindamycin in Patients With Periodontitis and Diabetes
Periodontitis is an inflammation of the supporting structures of the teeth, usually caused by specific or groups of microorganisms that results in the progressive destruction of the periodontal ligament and alveolar bone.
- Conditions
- Periodontitis, Periodontal Pocket, Diabetes Mellitus
- Trial name
- NCT03374176
- Testing
- Amoxicillin 500 mg / Metronidazole 250 mg, Clindamycin 300 mg
- Volunteers
- 42 people
- Sponsor
- Centro Universitario de Tonalá
Infection During Hemodialysis
Concentration of Ampicillin / Sulbactam and Amoxicillin / Clavulanic Acid in the Blood During Renal Replacement Therapy in Longterm Renal Replacement Therapy Patients
The study will be conducted to investigate the pharmacokinetics of ampicillin / sulbactam and amoxicillin/clavulanic acid during intermittent haemodialysis.
- Trial name
- NCT02007603
- Testing
- Administration of Amoxicillin / clavulanic acid, Ampicillin / sulbactam, Blooddraws for pharmacokinetic profiling
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Medical University of Vienna
Pneumonia
A Study to Assess the Efficacy and Safety of IV/PO Moxifloxacin in Subjects With Community-acquired Pneumonia
The purpose of this study is to assess if a therapy with oral and intravenous moxifloxacin is as effective as a therapy with intravenous ceftriaxone + intravenous azithromycin followed by oral amoxicilline/clavulanate and oral…
- Trial name
- NCT00717561
- Testing
- Avelox (Moxifloxacin, BAY12-8039), Ceftriaxone; Azithromycin; Amoxicilline/clavulanate; Clarithromycin
- Where
- 23 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Bayer