Clinical trials: Atorvastatin, completed
Hypercholesterolaemia
PULSAR - A Prospective Study to Evaluate the Utility of Low Doses of the Statins Atorvastatin and Rosuvastatin.
To compare reduction of LDL-C and safety between 10mg rosuvastatin and 20mg atorvastatin after 6 weeks treatment
- Trial name
- NCT00329173
- Testing
- Rosuvastatin, Atorvastatin
- Volunteers
- 1,000 people
- Sponsor
- AstraZeneca
Non ST Segment Elevation Acute Coronary Syndrome
COLchicine On-admission to Reduce Inflammation in Acute Coronary Syndrome (COLOR-ACS)
Since colchicine is known to have anti-inflammatory effects and inflammation is an early component of acute coronary syndrome (ACS), this study aims to evaluate the acute effects of low-dose colchicine, in addition to…
- Trial name
- COLOR-ACS (NCT05250596)
- Testing
- Colchicine, Atorvastatin
- Where
- 3 sites in Italy
- Volunteers
- 182 people
- Sponsor
- Azienda USL Toscana Centro
Diabetes, Hyperlipidemia, Mixed Dyslipidemia
Safety and Efficacy of Evolocumab in Combination With Statin Therapy in Adults With Diabetes and Hyperlipidemia or Mixed Dyslipidemia
The primary objective of this study was to evaluate the effect of 12 weeks of subcutaneous evolocumab (AMG 145) in combination with statin therapy (atorvastatin) on percent change from baseline in low-density lipoprotein…
- Trial name
- BERSON (NCT02662569)
- Testing
- Evolocumab, Atorvastatin
- Where
- 110 sites in United States, Argentina and 8 more
- Volunteers
- 986 people
- Sponsor
- Amgen
Breast Cancer, Breast Tumors
Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer
The purpose of this study is to determine the effects of combining metformin and atorvastatin treatment in patients with newly diagnosed breast cancer during the interval between breast biopsy and surgery.
- Conditions
- Breast Cancer, Breast Tumors, Cancer of Breast
- Trial name
- NCT01980823
- Testing
- Metformin, Atorvastatin, Breast surgery
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Columbia University
Acute Ischemic Stroke
Mechanical Thrombectomy in Acute Ischemic Stroke Beyond the Time of Window
Background: intravenous alteplase appears to be much less effective at opening proximal occlusions of the major intracranial arteries, which account for more than one third of cases of acute anterior-circulation stroke and…
- Trial name
- AIS (NCT04087382)
- Testing
- thrombectomy, non intervention group
- Where
- 2 sites in Egypt
- Volunteers
- 57 people
- Sponsor
- Assiut University
Dyslipidemias
To Assess the Safety, Efficacy and Tolerability of CKD-519, Administered With HMG-CoA Reductase Inhibitors
A multicenter, double-blind, parallel-group, active-controlled, dose-ranging study to assess the safety and efficacy of the novel cholesteryl ester transfer protein (CETP) inhibitor CKD-519 in combination with atorvastatin or…
- Trial name
- NCT02977065
- Testing
- Atorvastatin 20mg, Atorvastatin 20 mg + CKD-519 50 mg, Atorvastatin 20 mg + CKD-519 100 mg
- Where
- Australia
- Volunteers
- 62 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Covid19
Intermediate-dose vs Standard Prophylactic Anticoagulation and Statin vs Placebo in ICU Patients With COVID-19
In a 2x2 factorial design randomized controlled trial, the investigators aim to elaborate the safety and efficacy of two pharmacological regimens on outcomes of critically-ill patients with COVID-19.
- Trial name
- INSPIRATION (NCT04486508)
- Testing
- intermediate dose Enoxaparin/ unfractionated heparin, standard prophylactic dose Enoxaparin/ unfractionated heparin, Atorvastatin 20mg
- Where
- Iran
- Volunteers
- 600 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
Dyslipidemias, Coronary Heart Disease
Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the Blood
The primary purpose of this study is to compare the safety and efficacy of ABT-335 (investigational drug) coadministered with atorvastatin and ezetimibe to atorvastatin coadministered with ezetimibe in subjects with abnormal…
- Conditions
- Dyslipidemias, Coronary Heart Disease, Combined (Atherogenic) Dyslipidemia, Mixed Dyslipidemia
- Trial name
- NCT00639158
- Testing
- ABT-335, atorvastatin, ezetimibe
- Where
- 118 sites in United States
- Volunteers
- 543 people
- Sponsor
- Abbott
Coronary Artery Bypass Grafting
Efficacy of Different Perioperative Statin Regimens on the Protection Against Post Coronary Artery Bypass Grafting Major Adverse Cardio-cerebral Events
This study aims at comparing different perioperative statin regimens for the prevention of post CABG adverse events. This was a randomized, prospective clinical trial.
- Trial name
- NCT02706860
- Testing
- Atorvastatin
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hyperlipidemia
The Effects of Atorvastatin on Vulnerable Plaques in Untreated Dyslipidemic Patients.
Inflammation is important in the both pathogenesis and outcome of atherosclerosis. Plaques containing numerous inflammatory cells, particular macrophages, have a high risk of rupture.We hypothesize that statin-induced plaque…
- Trial name
- NCT00172419
- Testing
- Atorvastatin
- Where
- Taiwan
- Volunteers
- 43 people
- Sponsor
- National Taiwan University Hospital
Scleroderma
Atorvastatin for Microvascular Endothelial Function and Raynaud in Early Diffuse Scleroderma
The purpose of this study is to learn about the effect atorvastatin on blood vessel function and Raynaud symptoms in patients with early diffuse systemic sclerosis.
- Trial name
- TAMER (NCT02370784)
- Testing
- atorvastatin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Robyn T. Domsic, MD, MPH
Coronary Artery Disease
Statin Recapture Therapy Before Coronary Artery Bypass Grafting
Patients with coronary artery disease requiring coronary artery bypass grafting (CABG) are at risk for postoperative complications after surgery.
- Trial name
- StaRT-CABG (NCT01715714)
- Testing
- Statin Recapture Therapy
- Where
- 10 sites in Germany
- Volunteers
- 2,630 people
- Sponsor
- University of Cologne
Myocardial Infarction, Stem Cell Transplantation
Strengthening Transplantation Effects of Bone Marrow Mononuclear Cells With Atorvastatin in Myocardial Infarction
The benefit of current stem cell transplantation therapy for myocardial infarction is limited by low survival rate for stem cell.
- Conditions
- Myocardial Infarction, Stem Cell Transplantation, Angioplasty, Transluminal, Percutaneous Coronary
- Trial name
- STEM-AMI (NCT00979758)
- Testing
- Atorvastatin and mononuclear cells transplantation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Hypertension With Hyperlipidemia
Drug-drug Interaction Following Oral Administration of Telmisartan/Amlodipine and Atorvastatin in Healthy Adult Volunteers
study to evaluate drug-drug interaction following oral administration of telmisartan/amlodipine and atorvastatin in healthy adult volunteers
- Trial name
- NCT03461081
- Testing
- telmisartan/amlodipine and atorvastatin
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Myocardial Infarction
The Use of Statins for Myocardial Death Prevention
The administration of high dose HMG-CoA reductase inhibitors (Statins) to patients with acute ST-elevation MI (hypoxia/ischemia) who are treated with primary PCI (reoxygenation/ reperfusion) will protect their cardiomyocytes from…
- Trial name
- NCT00772564
- Testing
- Atorvastatin
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Rambam Health Care Campus
Angina, Stable
Acupuncture in Patients With Stable Angina Pectoris
This trail aims to evaluate the efficacy of acupoints on the specific meridian for chronic stable angina pectoris, compared with acupoints on the other meridian, sham acupoints and waiting-list.
- Trial name
- ASAP (NCT01686230)
- Testing
- acupuncture, Basic treatment
- Where
- China
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Hypertension, Hyperlipidemia
Efficacy and Safety of Irbesartan and Atorvastatin in Hypertension and Hyperlipidemia
The purpose of this study is to evaluate efficacy and safety of coadministered Irbesartan and Atorvastatin in patients with hypertension and hyperlipidemia.
- Trial name
- NCT01442987
- Testing
- Irbesartan/Atorvastatin A, Irbesartan, Atorvastatin A
- Where
- South Korea
- Volunteers
- 230 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Socket Preservation
Socket Augmentation Using Atorvastatin With Or Without PRGF (Clinical and Histomorphometric Study)
Despite the numerous studies describing the benefits of PRGF (plasma rich in growth factors) and Statins separately , there has been a lack of clinical investigation into the simultaneous use of these agents in socket…
- Trial name
- NCT03228771
- Testing
- PRGF/ATV, ATV gel
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypercholesterolemia
High Potency Statins and Acute Kidney Injury
Statins are a class of cholesterol lowering medications that are prescribed for the prevention and treatment of cardiovascular disease.
- Trial name
- NCT02518516
- Testing
- Rosuvastatin (≥10 mg), Atorvastatin (≥20 mg), Simvastatin (≥40 mg)
- Where
- Canada
- Volunteers
- 2,067,639 people
- Sponsor
- Canadian Network for Observational Drug Effect Studies, CNODES
Hyperlipidemia
Assess HDL-C Increase And Non-HDL Lowering Effect Of Torcetrapib/Atorvastatin Vs. Fenofibrate
The Torcetrapib project was terminated on December 2, 2006 due to safety findings. To assess the HDL-C increase and non-HDL lowering effect of torcetrapib/atorvastatin vs. fenofibrate.
- Trial name
- NCT00139061
- Testing
- Torcetrapib/Atorvastatin, Fenofibrate
- Where
- 26 sites in France
- Volunteers
- 128 people
- Sponsor
- Pfizer