Clinical trials: Atorvastatin, completed
Myocardial Infarction, Stroke
Using AtorVASTatin to Prevent VAscular Inflammatory OccLUSion in the Critically Ill
Patients are admitted to the critical care unit of the hospital because of medical conditions that have a high likelihood of causing severe problems with blood flow, breathing, or brain function.
- Conditions
- Myocardial Infarction, Stroke, Renal Failure
- Trial name
- VASTVALUS (NCT01073800)
- Testing
- atorvastatin 80 mg per os daily
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Hypercholesterolemia, Dyslipidemia
Clinical Trial to Evaluate the Efficacy and Safety of DW1125 and DW1125A
A Randomized, Double blind, Parallel, Multi-center, Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of DW1125 and DW1125A in Patient with primary Hypercholesterolemia or Mixed Dyslipidemia
- Trial name
- NCT05970679
- Testing
- Ezetimibe/Atorvastatin 10/5 mg, Atorvastatin 5mg, Ezetimibe 10mg
- Where
- South Korea
- Volunteers
- 252 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Statin Adverse Reaction
MUscle Side-Effects of Atorvastatin in Coronary Patients (MUSE) -Follow-up Study
Statins are cornerstone treatment in secondary cardiovascular disease (CVD) prevention. Today, statin non-adherence (patients not taking their prescribed drug) remains a major public health concern, leading to adverse outcomes in…
- Trial name
- NCT04453735
- Testing
- Atorvastatin mylan 40 Mg Oral Tablet
- Where
- 2 sites in Norway
- Volunteers
- 27 people
- Sponsor
- Vestre Viken Hospital Trust
Healthy
Bioequivalence Study of Atorvastatin Calcium Tablets, 80 mg of Dr. Reddy's Under Fed Conditions
The purpose of this study is to compare and evaluate the single-dose oral bioavailability and to monitor the safety of subjects.
- Trial name
- NCT01645423
- Testing
- Atorvastatin Calcium Tablets, 80 mg
- Where
- India
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy
A Clinical Study of Ulonivirine (MK-8507) With Atorvastatin and Metformin in Healthy Adults (MK-8507-018)
Researchers want to learn about ulonivirine when given with atorvastatin and metformin in healthy people. The goal of this study is to compare the amount of atorvastatin and metformin in a person's body over time when given with…
- Trial name
- NCT07530289
- Testing
- Atorvastatin, Metformin, Ulonivirine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Healthy
7-day Atorvastatin and Emotional Processing
Work in our group has revealed that short-term (7-day) administration of antidepressants produces positive biases in the processing of emotional information in healthy volunteers.
- Trial name
- NCT03966859
- Testing
- Atorvastatin 20mg
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Diabetes Mellitus
Aspirin Statins Or Both For The Reduction Of Thrombin Generation In Diabetic People
Despite formal recommendations, evidence of efficacy of aspirin in individuals with diabetes is scant and controversial. While the efficacy of aspirin versus placebo in patients with diabetes is currently under investigation in…
- Trial name
- RATIONAL (NCT00793754)
- Testing
- Aspirin, Atorvastatin, Aspirin + Atorvastatin
- Where
- Argentina
- Volunteers
- 30 people
- Sponsor
- Fundacion GESICA
Statin Adverse Reaction
MUscle Side-Effects of Atorvastatin in Coronary Patients
The study aims to estimate the effect of atorvastatin on muscular symptom intensity in coronary patients with subjective statin-associated muscle symptoms (SAMS) and to determine the association with blood levels of atorvastatin…
- Trial name
- MUSE (NCT03874156)
- Testing
- Atorvastatin 40mg
- Where
- 2 sites in Norway
- Volunteers
- 77 people
- Sponsor
- Vestre Viken Hospital Trust
Graft vs Host Disease
Atorvastatin for the Prophylaxis of Acute GVHD in Patients Undergoing Matched Sibling Allogeneic Transplantation
Atorvastatin for prevention of acute GVHD
- Trial name
- NCT01175148
- Testing
- Atorvastatin calcium (Lipitor)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- West Virginia University
Hypercholesterolemia
Bioavailability Study for New Atorvastatin Formulation
The purpose of this study is to estimate the relative bioavailability of the commercial tablet with one prototype extemporaneous preparation suspension formulation, to assist with internal decision making on formulation…
- Trial name
- NCT00844376
- Testing
- Atorvastatin suspension, Lipitor
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Acute Coronary Syndrome
FRANCIS-ACS Trial: A Study of the Safety and Efficacy of A 002 in Subjects With Acute Coronary Syndromes
The objective of this study is to evaluate the safety and efficacy of A 002 when added to high dose atorvastatin in subjects with an acute coronary syndrome (ACS)
- Trial name
- FRANCIS-ACS (NCT00743925)
- Testing
- Varespladib Methyl (A-002)
- Where
- 44 sites in Georgia, Russia and 1 more
- Volunteers
- 625 people
- Sponsor
- Anthera Pharmaceuticals
Metabolic Syndrome
Modified Huanglian Wendan Decoction for Metabolic Syndrome
This randomized controlled clinical study aims to evaluate the effect of Modified Huanglian Wendan Decoction on oxidative stress in patients with metabolic syndrome.
- Trial name
- NCT07702669
- Testing
- Lifestyle Intervention, Standard Therapy, Modified Huanglian Wendan Decoction
- Where
- China
- Volunteers
- 180 people
- Sponsor
- First Affiliated Hospital of Heilongjiang Chinese Medicine University
Hypercholesterolemia
A Long-term Safety and Tolerability Study of Ezetimibe Plus Atorvastatin in Participants With Coronary Heart Disease, Multiple Risk Factors, or Hypercholesterolemia Not Controlled by Atorvastatin (P01418/MK-0653-032)
The purpose of this study was to evaluate the long-term safety and tolerability of ezetimibe 10 mg once daily co-administered with atorvastatin 10 to 80 mg daily for up to 12 consecutive months in participants with heterozygous…
- Trial name
- NCT03882996
- Testing
- Ezetimibe, Atorvastatin
- Volunteers
- 432 people
- Sponsor
- Organon and Co
Dyslipidemia
TA-8995: Its Use in Patients With Mild Dyslipidaemia (TULIP)
The primary objective of this study is to evaluate the efficacy of different doses of TA-8995, a cholesteryl ester transfer protein (CETP) inhibitor, on the elevation of high-density lipoprotein cholesterol (HDL-C) and reduction…
- Trial name
- TULIP (NCT01970215)
- Testing
- TA-8995, Atorvastatin, Rosuvastatin
- Where
- 17 sites in Denmark, Netherlands
- Volunteers
- 364 people
- Sponsor
- Xention Ltd
Hypercholesterolemia
A Multicenter, Randomized, Open Label Study to Evaluate the Lipid Lowering Efficacy and Safety of Vytorin® 10/20 vs. Atorvastatin 10mg in Hypercholesterolemia Patients With Metabolic Syndrome in Korea (0653A-129)(COMPLETED)
Prevalence of metabolic syndrome in korea is increasing. There is no clinical trial targeting on such increasing populations like metabolic syndrome patients with Vytorin® in korea.
- Trial name
- NCT00496730
- Testing
- simvastatin (+) ezetimibe, Comparator: atorvastatin
- Volunteers
- 256 people
- Sponsor
- Organon and Co
Hypercholesterolemia
Ezetimibe Plus (+) Simvastatin Versus Atorvastatin Comparative Study (0653A-092)(COMPLETED)
This is an efficacy and safety study of Vytorin (ezetimibe (+) simvastatin) compared to atorvastatin (ezetimibe/simvastatin) at week 6 in primary hypercholesterolemia patients in Korea.
- Trial name
- NCT00166504
- Testing
- ezetimibe (+) simvastatin, atorvastatin
- Volunteers
- 203 people
- Sponsor
- Organon and Co
Atrial Fibrillation, Neuropsychology
Silent Cerebrovascular Lesion and Cognitive Decline Prevention by Cholesterol Lowering in Elderly AF Patients
In elderly patients with atrial fibrillation (AF) the presence of silent brain infarcts and neurocognitive deficit is high despite adequate treatment with oral anticoagulation.
- Conditions
- Atrial Fibrillation, Neuropsychology, Magnetic Resonance Imaging, Inflammation
- Trial name
- SPACE (NCT00449410)
- Testing
- Atorvastatin, ezetimibe
- Where
- Netherlands
- Volunteers
- 35 people
- Sponsor
- Radboud University Medical Center
Healthy Volunteers
A Phase 1 Study to Evaluate the Drug-Drug Interaction Potential Between ALG-055009 and Statin Therapy(Ies)
This Phase 1 study consists of two parts, all conducted in healthy volunteers (HVs). In Parts 1 and 2, the drug-drug interaction (DDI) potential of ALG-055009 will be explored, where subjects will be assigned to receive multiple…
- Trial name
- NCT06191991
- Testing
- Atorvastatin, ALG-055009, Rosuvastatin
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Aligos Therapeutics
Coronary Artery Disease, Menopause
Serum Concentration of Endogenous Estrogens and Sirtuin-1 After Administration of Atorvastatin and Quercetin:
Chronic coronary syndrome (CCS) is the leading cause of death in women in the most developed regions of Brazil. The primary etiopathogenic mechanism is the process of atherosclerosis.
- Trial name
- NCT05877235
- Testing
- Quercetin
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- InCor Heart Institute
Hepatitis C
Dose Finding Trial of Rosuvastatin and Atorvastatin Versus Hepatitis C
Different Doses of rosuvastatin and atorvastatin will be used to see if HCV viral load changes and liver tests change.
- Trial name
- NCT00446940
- Testing
- rosuvastatin, atorvastatin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Bader, Ted, M.D.