Clinical trials: Azithromycin, completed
Plasmodium Falciparum Infection
Chloroquine Alone or in Combination for Malaria in Children in Malawi
Malaria is a sickness caused by a germ that can get into a person's body when a mosquito bites them. It can cause fever, headache, body aches and weakness. It can even cause death, especially in children.
- Trial name
- NCT00379821
- Testing
- Atovaquone-proguanil, Artesunate, Azithromycin
- Where
- Malawi
- Volunteers
- 640 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Tonsillitis
A Multicenter, Randomized, Double-Blind, Double-Dummy Study Of Azithromycin SR Versus Amoxicillin For The Treatment Of Strep Throat In Children
The objective was to determine if a single 60 mg/kg dose of azithromycin SR was as safe and effective as a 10-day regimen of amoxicillin (45 mg/kg/day, given in divided doses every 12 hours) when used to treat children with strep…
- Trial name
- NCT00643149
- Testing
- amoxicillin, azithromycin SR
- Where
- 46 sites in United States, Canada and 3 more
- Volunteers
- 693 people
- Sponsor
- Pfizer
Mycobacterium Avium-intracellulare Infection, HIV Infections
A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive Patients
This study is designed to find out whether HIV-positive patients whose immune systems have improved after receiving anti-HIV treatment should take azithromycin to prevent Mycobacterium avium complex (MAC) disease.
- Trial name
- NCT00000947
- Testing
- Azithromycin
- Where
- 19 sites in United States
- Volunteers
- 850 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ureaplasma, Bacterial Infection
An Open Label Evaluation of the Pharmacokinetics and Safety of Single Dose Intravenous Azithromycin in Preterm Neonates
The purpose of this study is to evaluate the pharmacokinetics and safety of a single dose of IV azithromycin in preterm neonates and confirm that the pharmacokinetics of azithromycin is similar in the 24-<32 week and 32-<37 week…
- Trial name
- NCT00760279
- Testing
- Azithromycin
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Child Mortality, Azithromycin
Resiliency Through Azithromycin for Children (REACH), Côte d'Ivoire
The aim of the study is to gather preliminary evidence on the operational feasibility and acceptability of integrating bi-annual mass drug administration (MDA) of single-dose azithromycin for children ages 1 to 11 months in high…
- Trial name
- REACH (NCT04617626)
- Testing
- Azithromycin
- Where
- Côte d’Ivoire
- Volunteers
- 1,735 people, healthy volunteers welcome
- Sponsor
- FHI 360
Healthy
Fed Study of Azithromycin Tablets 600 mg to Zithromax® Tablets 600 mg
The objective of this study was to investigate the bioequivalence of Mylan's azithromycin 600 mg tablets to Pfizer's Zithromax® 600 mg tablets following a single, oral 600 mg (1 x 600 mg) dose administered under fed conditions.
- Trial name
- NCT00649935
- Testing
- Azithromycin Tablets 600 mg, Zithromax® Tablets 600 mg
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Sinusitis
Zmax Compared to Augmentin in Sinusitis
This study will enroll patients with Bacterial Sinusitis who will be treated with either Zmax (Azithromycin Extended Release) or Augmentin (Amoxicillin/Clavulanate).
- Trial name
- NCT00367120
- Testing
- Azithromycin Extended Release, Amoxicillin/Clavulanate
- Volunteers
- 762 people
- Sponsor
- Pfizer
Community-Acquired Pneumonia (CAP)
Intravenous Azithromycin Plus Intravenous Ceftriaxone Followed by Oral Azithromycin With Intravenous Levofloxacin Followed by Oral Levofloxacin for the Treatment of Moderate to Severely Ill Hospitalized Patients With Community Acquired Pneumonia
A trial in which patients over 18 years of age who are hospitalized with community acquired pneumonia and are otherwise eligible for entry into the study are randomly selected to receive one of two treatment regimens.
- Trial name
- NCT00035347
- Testing
- IV azithromycin, ceftriaxone, oral azithromycin
- Where
- 37 sites in United States, Canada and 3 more
- Volunteers
- 219 people
- Sponsor
- Pfizer
Autoimmune Diseases
A Single and Repeat Dose PK/PD Study to Characterise Biomarker Response in Healthy Subjects Treated With Azithromycin
This is a two part protocol (Parts A and B) in healthy volunteers evaluating the pharmacokinetics/ pharmacodynamics (PK/PD) of azithromycin to investigate the usefulness of various biomarkers (e.g., Interleukin-10 (IL-10)…
- Trial name
- NCT01416350
- Testing
- Azithromycin - 250 mg, Azithromycin - 1000 mg, Azithromycin - 250 mg every other day for 3 weeks
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cystic Fibrosis, Bronchiectasis
Prevention of Bronchiectasis in Infants With Cystic Fibrosis
The general aim of this project is to conduct a randomized, double-blind, placebo-controlled clinical trial of azithromycin to determine whether treatment from infancy is safe and will prevent the onset of bronchiectasis.
- Trial name
- COMBATCF (NCT01270074)
- Testing
- Azithromycin
- Where
- 10 sites in Australia, New Zealand
- Volunteers
- 130 people
- Sponsor
- The University of Queensland
Pertussis
Vanderbilt Pertussis Exposure Study: PEP in Vaccinated Healthcare Workers Following Pertussis Exposure
The purpose of this study is to compare the effectiveness of two strategies of post-exposure prophylaxis (PEP) in healthcare workers (HCWs) who have been vaccinated with acellular pertussis vaccine and have been exposed to…
- Trial name
- VPES (NCT00469274)
- Testing
- Antibiotic PEP
- Where
- United States
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Gonorrhoea
Efficacy of Combination Therapies for Gonorrhea Treatment
The purpose of this study is to learn how to better treat gonorrhea infections. Gonorrhea is a sexually transmitted disease (STD) that is usually cured with a single antibiotic.
- Trial name
- NCT00926796
- Testing
- Azithromycin, Gentamicin, Gemifloxacin
- Where
- 5 sites in United States
- Volunteers
- 614 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Chlamydial Infection
YCFM (Youth Correctional Facilities Males)
The proposed study is a single center (with multiple long-term YCFs) treatment trial of the CDC-recommended azithromycin regimen (1 gm PO once) for chlamydia in males.
- Trial name
- NCT03249935
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acne Vulgaris
Comparing Efficacy of Azithromycin and Probiotics for Treatment of Acne Vulgaris
the goal of this clinical trial is to measure the efficacy of probiotics for treatment of acne vulgaris, to compare it with azithromycin and to measure the synergistic effect of azithromycin and probiotics for treatment of acne…
- Trial name
- NCT05629468
- Testing
- Azithromycin, Probiotic Formula, Benzoyl Peroxide 4 % Topical Cream
- Where
- Pakistan
- Volunteers
- 75 people
- Sponsor
- Pak Emirates Military Hospital
Neisseria Gonorrhoeae
Trial Comparing Ceftriaxone Plus Azithromycin Versus Ceftriaxone for the Treatment of Gonorrhea
In this Randomized Controlled Trial, the investigators will recruit 42 men attending the STI and HIV clinic at the Institute of Tropical Medicine, with a diagnosis of N.
- Trial name
- ResistAZM (NCT05027516)
- Testing
- Rocephin, Azithromycin
- Where
- Belgium
- Volunteers
- 42 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Fatty Liver, Liver Dysfunction
The Effect of Helicobacter Pylori Eradication on Liver Fat Content in Non-alcoholic Fatty Liver Disease
The role of Helicobacter pylori(HP)in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) is controversial.
- Conditions
- Fatty Liver, Liver Dysfunction, Insulin Resistance
- Trial name
- NCT01876108
- Testing
- H.pylori eradication (Omeprazole, Amoxicillin, Bismuth subcitrate, Azithromycin)
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Tehran University of Medical Sciences
Mycobacterium Avium-Intracellulare Infection, HIV Infections
Tolerance, Safety, and Activity of Rifapentine Alone and in Combination Therapy in AIDS Patients With Mycobacterium Avium Complex Bacteremia.
To determine the antimicrobial activity and tolerability of rifapentine alone and in combination therapy in patients with AIDS and disseminated Mycobacterium avium complex (MAC) bacteremia.
- Trial name
- NCT00002192
- Testing
- Rifapentine, Ethambutol hydrochloride, Clarithromycin
- Where
- United States
- Sponsor
- Anderson Clinical Research
Acute Respiratory Tract Infection, Acute Respiratory Insufficiency
An Open Randomized Study of Dalargin Efectiveness in Combination With Leitragin Drug in Patients With Severe and Critical Manifestations of SARS-COVID-19
The purpose of the study is to evaluate an effectiveness of the drug Dalargin in combination with Leitragin for the prevention and treatment of severe pulmonary complications symptoms associated with severe and critical…
- Conditions
- Acute Respiratory Tract Infection, Acute Respiratory Insufficiency, Pneumonia, Septic Shock
- Trial name
- NCT04346693
- Testing
- Standard therapy recommended by the Ministry of Health of the Russian Federation., Standard therapy recommended by the Ministry of Health of the Russian Federation and Leitragin intramuscular injection, Standard therapy recommended by the Ministry of Health of the Russian Federation and Leitragin inhalation
- Where
- Russia
- Volunteers
- 320 people
- Sponsor
- Burnasyan Federal Medical Biophysical Center
Bronchiectasis
Efficacy of Azithromycin in Treatment of Bronchiectasis
Bronchiectasis is a chronic lung condition characterised primarily by dilatation of the airways. Only a small number of clinical studies have been conducted investigating the use of macrolides to treat non-cystic fibrosis…
- Trial name
- NCT02107274
- Testing
- Azithromycin
- Where
- Malaysia
- Volunteers
- 78 people
- Sponsor
- Penang Hospital, Malaysia
Eye Infections, Bacterial
Ocular Pharmacokinetics After a Single Drop Instillation of T1225 0.5, 1, 1.5% in 91 Healthy Volunteers
To evaluate azithromycin tear concentrations after instillation of one drop of one of the three T1225 concentrations (0.5%, 1% and 1.5%) and to evaluate the ocular safety.
- Trial name
- NCT00356850
- Testing
- Azithromycin
- Volunteers
- healthy volunteers welcome
- Sponsor
- Laboratoires Thea