Clinical trials: Azithromycin
Gonorrhea, Neisseria Gonorrhoeae
Washington State Community Expedited Partner Treatment (EPT) Trial
The Washington State Community Expedited Partner Therapy Trial is a stepped-wedge community level randomized trial designed to test the hypothesis that a public health program designed to increase the use of expedited partner…
- Conditions
- Gonorrhea, Neisseria Gonorrhoeae, Chlamydia Trachomatis
- Trial name
- NCT01665690
- Testing
- Patient delivered partner therapy, Targeted public health partner services
- Where
- 2 sites in United States
- Volunteers
- 33,222 people
- Sponsor
- University of Washington
Rocky Mountain Spotted Fever
Efficacy of Azithromycin Plus Doxycycline Versus Doxycycline Plus Placebo in Patients With Rocky Mountain Spotted Fever
The aim of this study is to impove the pharmacological treatment of Rocky mountain spotted fever, since is a very ancient disease with an antibiotic therapy that have not changed much the mortality rates, being compared with the…
- Trial name
- Rocky-Z (NCT05398055)
- Testing
- Azithromycin + Doxycycline
- Where
- Mexico
- Volunteers
- 86 people
- Sponsor
- Hospital General de Mexicali
Crohn's Disease Relapse, Biological Substance; Adverse Effect
Pre-treatment With Azithromycin to Reduce Immunogenicity to to Anti-TNF Agents in Patients With Crohn's Disease
This is a randomized placebo-controlled trial in Crohn's disease patients before initiation of anti-tumor necrosis factor-α (anti-TNF) therapy that aims to test the effect of a pre-treatment short course of azithromycin therapy…
- Trial name
- AZITRATIM (NCT05599347)
- Testing
- Azithromycin Pill
- Where
- 9 sites in Israel
- Volunteers
- 180 people
- Sponsor
- Rambam Health Care Campus
Covid19
Clarithromycin Versus Azithromycin in Treatment of Mild COVID-19 Infection
The current study was conducted at Qena Governorate, Egypt, during the period from May 2020, to July 2020. The study included 305 COVID-19 cases diagnosed by PCR, patients were randomly assigned to one of three study limps…
- Trial name
- NCT04622891
- Testing
- Clarithromycin 500mg, Azithromycin
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- South Valley University
Lymphatic Filariasis, Yaws
PK PD Study of IDA and Azithromycin for NTDs ( ComboNTDs )
This is a Pharmacokinetic and Pharmacodynamic study evaluating the safety of co-administering Azithromycin alongside the new IDA (Ivermectin, Diethylcarbamazine, Albendazole) combination treatment for LF.
- Conditions
- Lymphatic Filariasis, Yaws, Trauma
- Trial name
- NCT03664063
- Testing
- Azithromycin, Albendazole, Ivermectin
- Where
- Papua New Guinea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Lihir Medical Centre
Pneumonia, Acute Exacerbation of Chronic Obstructive Airways Disease
Procalcitonin as a Marker of Antibiotic Therapy in Patients With Lower Respiratory Tract Infections
The purpose of this study is to investigate weather or not the use of a procalcitonin(PCT)-based treatment in the daily clinical work could lower the consumption of antibiotics in patients with lower respiratory tract infections.
- Trial name
- NCT02171338
- Testing
- PCT-level, Antibiotic treatment based on PCT-level
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Holbaek Sygehus
Bronchiolitis Obliterans Syndrome
Early Detection and Management of Bronchiolitis Obliterans Syndrome Following Pediatric Hematopoietic Stem Cell Transplantation
This study aims to determine whether or not early spirometric detection and management of obstructive lung disease with combined fluticasone/azithromycin/montelukast therapy (FAM) can attenuate declining lung function, prevent…
- Trial name
- NCT03072849
- Testing
- Pulmonary function testing, FAM Therapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Atypical Pneumonia
Treatment and Vaccine Development of Mycoplasma Pneumoniae
A randomized clinical trial comparing treatment effectiveness of azithromycin and doxycycline for pediatric Mycoplasma pneumonia.
- Trial name
- NCT03911440
- Testing
- Doxycycline, Azithromycin
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Dermatitis, Allergic Contact
Clinical Observations of Pain and Pruritus Induced by Exposure to Allergic Contact Dermatitis Caused by Macrolides
Clinical side effects of macrolides in addition to the common gastrointestinal reactions, recently it has been found that the incidence of local reactions after injection is relatively high, such as pain and itching and local…
- Trial name
- NCT06574204
- Testing
- Erythromycin, Azithromycin, physiological saline
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Nantong University
Trachoma, Chlamydia
Tripartite International Research for the Elimination of Trachoma
Mass antimicrobial administrations have been remarkably successful in reducing the prevalence of the ocular strains of Chlamydia that cause trachoma.
- Trial name
- TIRET (NCT01202331)
- Testing
- mass treatment with oral azithromycin
- Where
- Ethiopia
- Volunteers
- 29,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pneumonia, Viral, Respiratory Failure
A Study of the Effectiveness of an Off Label Mefloquine Use for the Treatment of Patients With COVID19
Study of the effectiveness and safety of the drug Mefloquine, tablets 250 mg, produced by FSUE "SPC" Farmzaschita " FMBA of Russia (Russia), in comparison with the drug Hydroxychloroquine, tablets 200 mg, for the treatment of…
- Trial name
- NCT04347031
- Testing
- Mefloquine, Hydroxychloroquine, Mefloquine + azithromycin + / - tocilizumab
- Where
- Russia
- Volunteers
- 320 people
- Sponsor
- Burnasyan Federal Medical Biophysical Center
Bronchiolitis Obliterans
Targeted Therapy of Bronchiolitis Obliterans Syndrome
This phase II trial studies how well giving fluticasone propionate, azithromycin, and montelukast sodium (FAM) together works in treating patients with bronchiolitis obliterans who previously underwent stem cell transplant.
- Trial name
- FAM for BOS (NCT01307462)
- Testing
- fluticasone propionate, montelukast sodium, azithromycin
- Where
- 11 sites in United States
- Volunteers
- 36 people
- Sponsor
- Stephanie Lee
SARS-CoV-2, COVID-19
VA Remote and Equitable Access to COVID-19 Healthcare Delivery (VA-REACH TRIAL)
We propose a 3-arm RCT to determine the efficacy of hydroxychloroquine or azithromycin in treating mild to moderate COVID-19 among Veterans in the outpatient setting.
- Trial name
- VA-REACH (NCT04363203)
- Testing
- Hydroxychloroquine, Azithromycin
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Salomeh Keyhani MD
COVID
Ivermectin-Azithromycin-Cholecalciferol (IvAzCol) Combination Therapy for COVID-19
As the world faces COVID-19, the search for effective treatments against the disease and its complications has turned its gaze to drugs that are classically used in other infectious diseases.
- Trial name
- IvAzCol (NCT04399746)
- Testing
- Ivermectin, Azithromycin, Cholecalciferol
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
Bronchopulmonary Dysplasia
Azithromycin in the Prevention of Lung Injury in Premature Newborn
The introduction of invasive mechanical ventilation in the treatment of preterm infants works as an adjuvant in the treatment of acute respiratory failure, which has resulted in significantly significant survival rates.
- Trial name
- NCT03485703
- Testing
- Azithromycin
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Sars-CoV2, COVID-19
Efficacy and Safety of Hydroxychloroquine and Favipiravir in the Treatment of Mild to Moderate COVID-19
This is an open-label, multicenter, parallel-group, randomized, phase III trial that evaluates the efficacy and safety of hydroxychloroquine and favipiravir in the treatment of patients with possible or confirmed COVID-19…
- Trial name
- NCT04411433
- Testing
- Favipiravir (3200 mg + 1200 mg), Favipiravir (3600 mg + 1600 mg), Favipiravir (3200 mg + 1200 mg) combined with Hydroxychloroquine
- Where
- Turkey (Türkiye)
- Volunteers
- 1,008 people
- Sponsor
- Ministry of Health, Turkey
Syphilis
Azithromycin/Bicillin Syphilis
The purpose of this study is to determine if azithromycin, a drug approved for treatment of other infections, is as effective for syphilis (a sexually transmitted disease) as the standard treatment.
- Trial name
- NCT00031499
- Testing
- Azithromycin, Benzathine Penicillin, Doxycycline
- Where
- 10 sites in United States, Madagascar
- Volunteers
- 593 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Childhood Asthma With Acute Exacerbation
Antibiotic Treatment of Recurrent Episodes of Asthma in Children
Copsac has discovered that asthmatic exacerbations are as closely linked to bacterial as to viral infection. The current study will examine whether treatment of asthmatic exacerbations with macrolide antibiotics - in the abscence…
- Trial name
- AB-studie (NCT01233297)
- Testing
- Azithromycin
- Where
- 2 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Copenhagen Studies on Asthma in Childhood
Pneumonia, Ventilator-Associated, Pseudomonas Infections
Azithromycin as a Quorum-Sensing Inhibitor for the Prevention of Pseudomonas Aeruginosa Ventilator-Associated Pneumonia
The purpose of this study is to assess the clinical efficacy of azithromycin, used as a quorum-sensing blocker, when compared to placebo for preventing or delaying the occurrence of pneumonia in ventilated patients colonized with…
- Trial name
- NCT00610623
- Testing
- azithromycin
- Where
- 20 sites in Belgium, France and 4 more
- Volunteers
- 92 people
- Sponsor
- Anbics Management-Services Ag
Chlamydial Infection
YCFM (Youth Correctional Facilities Males)
The proposed study is a single center (with multiple long-term YCFs) treatment trial of the CDC-recommended azithromycin regimen (1 gm PO once) for chlamydia in males.
- Trial name
- NCT03249935
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)