Clinical trials: Best Practice
Head and Neck Carcinoma
A Financial Intervention (Financial Compass) to Identify and Address Financial Hardship Among Head and Neck Cancer Patients, Financial Compass Trial
This clinical trial compares the effect a financial intervention, called Financial Compass, to usual care in identifying and addressing financial hardship in patients with head and neck cancer.
- Trial name
- NCT06896695
- Testing
- Best Practice, Discussion, Financial Navigation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Roswell Park Cancer Institute
Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
PLAN Intervention to Enhance Engagement of Latino Cancer Patients in Advanced Care Planning
This trial tests whether Planning for Your Advance Care Needs (PLAN) intervention works to enhance Latino patients' understanding of and engagement in advanced care planning.
- Trial name
- NCT04889144
- Testing
- Communication Intervention, Best Practice, Questionnaire Administration
- Where
- 4 sites in United States
- Volunteers
- 27 people
- Sponsor
- Fred Hutchinson Cancer Center
Dating Violence, Alcohol Drinking
Evaluation of PRYSHM for LGBTQIA2S+ Youth
The overarching goal of the proposed project is to develop an innovative, online synchronous DV and AU prevention curriculum created specifically for SGMY (ages 15 to 18); conduct a pilot randomized controlled trial to assess its…
- Trial name
- PRYSHM (NCT05521906)
- Testing
- Promoting Resilient Youth with Strong Hearts and Minds (PRYSHM)
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- University of Nebraska Lincoln
Children With Complex Chronic Conditions
Garnering Effective Telehealth 2 Help Optimize Multidisciplinary Team Engagement
The purpose of this study is to determine the effectiveness of the GET2HOME Intervention bundle.
- Trial name
- GET2HOME (NCT05568355)
- Testing
- GET2HOME Intervention
- Where
- United States
- Volunteers
- 638 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Patient Safety
Openness and Learning Joint Commission: Using Patient Experience for Improvement Following a Patient Safety Event
The focus of our work is openness, learning and person-centred involvement following patient safety incidents in health care. We will explore patients, carers and relatives' perspectives on what is important to them, what…
- Trial name
- NCT04897087
- Testing
- patient safety event
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- NHS Education for Scotland
Postpartum Hemorrhage, Vaginal Delivery
Reducing Postpartum Hemorrhage After Vaginal Delivery
Postpartum hemorrhage is the primary cause threatening the life safety of pregnant women in the world and China, and also the main cause of hysterectomy for women giving birth.
- Trial name
- NCT05501106
- Testing
- Integrated Improvement strategies
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University Third Hospital
Coronary Heart Disease
Remote Maintenance Cardiac Rehabilitation
The investigators would like to test the feasibility of a remotely prescribed and monitored exercise program in people with coronary heart disease, using a wearable activity device and text message support, compared to usual care…
- Trial name
- MAINTAIN (NCT05292287)
- Testing
- Polar Ignite Wearable Activity Monitor
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Coventry University
Hearing and Vision Loss
Validating a Self-fitting Hearing Aid
Eargo, Inc. has developed a hearing aid that contains self-fitting gain software that allows adults with mild-to-moderate hearing loss to test their hearing sensitivity and program hearing aids to match their measured hearing…
- Trial name
- NCT05246904
- Testing
- Fitting algorithm
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Minnesota
Systemic Sclerosis
Seoul National University Hospital Systemic Sclerosis Cohort
To establish a new prospective cohort of Korean patients with systemic sclerosis and track the natural history of the disease over time. To generate new hypotheses for further investigation.
- Trial name
- NCT02819947
- Testing
- This is an observational prospective study.
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Technology
Effectiveness of a Smart Hearing Aid on Improving Psychosocial Well-being in Elderly
The study has 2 primary research questions, 4 secondary research questions, and 2 auxiliary research questions targeting elderly with hearing impairment. The research questions are: Primary study questions: 1.
- Trial name
- NCT05772949
- Testing
- Experimental group intervention, Wait-list control group intervention
- Where
- 3 sites in Hong Kong
- Volunteers
- 33 people
- Sponsor
- The University of Hong Kong
Cancer-Associated Anorexia, Head and Neck Squamous Cell Carcinoma
Olanzapine for Managing Anorexia in Head and Neck Cancer Patients Undergoing Chemoradiation, MACRO Trial
This phase II trial compares the effect of adding olanzapine to standard of care symptom management for nausea to standard of care alone in managing an abnormal loss of the appetite for food (anorexia) in patients treated with…
- Conditions
- Cancer-Associated Anorexia, Head and Neck Squamous Cell Carcinoma, Neck Squamous Cell Carcinoma of Unknown Primary
- Trial name
- NCT06995508
- Testing
- Best Practice, Olanzapine, Questionnaire Administration
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Roswell Park Cancer Institute
Back Pain
Determining the Impact of a New Physiotherapist Led Primary Care Model for Back Pain
This is a pilot cluster randomized controlled trial to determine the feasibility of a cluster randomized trial to evaluate the individual and health system impact of implementing a new physiotherapist-led primary care model for…
- Trial name
- NCT03320148
- Testing
- Physiotherapist-led primary care model for back pain, Usual care
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Queen's University
Autism Spectrum Disorder
Neuro Strengths-Based Approach to Autism
The Neuro-Strength-Based Approach to Autism (NSBAA) attempts to translate what research has discovered about the autistic brain into terms that autistics, and those involved with autistics, can understand.
- Trial name
- NSBAA (NCT05499910)
- Testing
- NSBAA
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Baio Enterprises
Depression, Anxiety, Anger
Advancing Family Wellbeing Through a Massive Open Online Intervention: The LightBEAM Program
Early childhood is a critical period for developmental outcomes, and the parent-child relationship plays a vital role in shaping cognitive and social development.
- Conditions
- Depression, Anxiety, Anger, Parenting, Stress Psychological
- Trial name
- NCT07026838
- Testing
- The Light Building Emotional Awareness and Mental Health (BEAM) Program
- Where
- Canada
- Volunteers
- 202 people
- Sponsor
- University of Manitoba
Alzheimer Disease, Dementia
CONSTELLATIONS Living Lab: Improving the Care Transitions of Older Adults Living with Neurocognitive Disorders
The prevalence of major neurocognitive disorders (MNCDs), particularly Alzheimer's disease, among older adults is increasing. These individuals and their caregivers often face challenges due to inefficient and poorly coordinated…
- Conditions
- Alzheimer Disease, Dementia, Neurocognitive Decline
- Trial name
- NCT06608589
- Testing
- CoMPAS+ MNCDs Program - Quality improvement program targeting the care transitions of patients living with a major neurocognitive disorder and their caregivers
- Where
- Canada
- Volunteers
- 700 people
- Sponsor
- Laval University
Diabetes Mellitus, Type 2
PROmoting Diabetes Education and Management Through Peer Support and Team Referral
A 3-step project is proposed. Step 1 will test which BPA time point(s) maximize referral rates to DSMES services in the real world clinic setting (Aim 1).
- Trial name
- PROMPT (NCT05587348)
- Testing
- Best Practice Advisory, Peer Support, Usual Care
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of North Carolina, Chapel Hill
ANEMIA
Anemia Management in Chronic Kidney Disease Not on Dialysis Patients After the European Renal Best Practice (ERBP) Working Group Recommendations
The purpose of this study is to evaluate the impact of the last recommendations of the European Anemia Working Group ERBP in the anemia management in the achievement of the therapeutic goal of Hb 11-12 g/dL.
- Trial name
- ACERCA (NCT01903148)
- Where
- 29 sites in Spain
- Volunteers
- 455 people
- Sponsor
- Fundación Senefro
Stroke
Predicting Ipsilesional Motor Deficits in Stroke With Dynamic Dominance Model
This study will test the hypothesis that the combination of low-moderate to severe motor deficits in the paretic arm and persistent motor deficits in the less-impaired arm limits functional independence in chronic stroke…
- Trial name
- NCT03634397
- Testing
- Less-Impaired Arm Training, Contralesional Arm Comparison
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Robert L. Sainburg
Tobacco Use Disorder, Substance Use Disorder
Smoking Cessation CM for Veterans With or at Risk for Cancer
Tobacco use among US Veterans poses significant health problems and challenges to their overall well-being. The aim of this project is to evaluate the effectiveness of a program called Contingency Management (CM) in helping…
- Trial name
- CM_TUD_Cancer (NCT06432985)
- Testing
- Focus Group, Contingency Management (CM), TUD Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anxiety, No Evidence of Disease
Video-Based Intervention in Reducing Anxiety in Patients Undergoing Lung Cancer Screening
This pilot trial studies a video-based intervention in reducing anxiety in patients undergoing lung cancer screening. Giving a video-based intervention to patients prior to lung cancer screening may reduce anxiety and improve the…
- Conditions
- Anxiety, No Evidence of Disease, Lung Carcinoma
- Trial name
- NCT02288416
- Testing
- educational intervention, questionnaire administration, quality-of-life assessment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center