Clinical trials: Best Practice, completed
Hearing Loss
Early Auditory Referral in Primary Care
Busy Primary Care providers (PCPs) have complex practices with many competing demands, making it difficult to improve their HL identification rates.
- Trial name
- EAR-PC (NCT03004937)
- Testing
- Family Medicine Hearing Loss Best Practice Alert
- Where
- 10 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Malignant Head and Neck Neoplasm
Expiratory Muscle Strength Training in Improving Bulbar Function and Quality of Life in Patients With Head and Neck Cancer
This randomized clinical trial studies how well expiratory muscle strength training works in improving bulbar function and quality of life in patients with head and neck cancer.
- Trial name
- NCT03175289
- Testing
- Best Practice, Educational Intervention, Exercise Intervention
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Chronic Pain
Blood Flow - an Underlying Mechanism Behind Clinical Improvements in Patients With Subacromial Pain Syndrome?
The purpose of this randomized clinical trial is two-fold. Firstly to see if patients suffering Subacromial Pain Syndrome can improve blood flow in the supraspinatus muscle in their shoulder, and secondly to investigate how…
- Trial name
- NCT02701465
- Testing
- Exercise: local high intensity interval exercise, Exercise: best clinical practice
- Where
- Norway
- Volunteers
- 24 people
- Sponsor
- Norwegian University of Science and Technology
Tobacco Use Treatment
Dentistry United to Extinguish Tobacco
System level strategies for implementing tobacco use treatment guidelines exist but are insufficiently put into practice, particularly in dental care settings.
- Trial name
- DUET (NCT01615237)
- Testing
- Audit and performance feedback (PF), Financial Incentive (P4P), Current Best Practices (CBP)
- Where
- 2 sites in United States
- Volunteers
- 3,207 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Anxiety, No Evidence of Disease
Video-Based Intervention in Reducing Anxiety in Patients Undergoing Lung Cancer Screening
This pilot trial studies a video-based intervention in reducing anxiety in patients undergoing lung cancer screening. Giving a video-based intervention to patients prior to lung cancer screening may reduce anxiety and improve the…
- Conditions
- Anxiety, No Evidence of Disease, Lung Carcinoma
- Trial name
- NCT02288416
- Testing
- educational intervention, questionnaire administration, quality-of-life assessment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Tropical Infectious Diseases
Optimizing Sysmex Technology as an Innovative Tool to Differentiate Between Malaria (PALUdism) and BACterial Infections in a Malaria Endemic Region
Severe malaria and bacterial Blood Stream Infections (bBSI) are impossible to differentiate clinically. This poses a particular threat in low resource areas, where bBSI is often not diagnosed due to the unavailability of rapid…
- Trial name
- PALUBAC (NCT02669823)
- Testing
- None, treatment as actual best practice
- Where
- Burkina Faso
- Volunteers
- 930 people
- Sponsor
- Sysmex Europe GmbH
Leg Ulcers
Safety Evaluation of Biatain Ibu in Painful Chronic Venous Leg Ulcers
The objective of this open label extension study (extension to study DK143WS) is to evaluate the safety of Biatain Ibu during 6 -12 weeks of exposure and during a 40 - 46 weeks safety follow-up period.
- Trial name
- NCT00628004
- Testing
- Biatain Ibu, Local best practice
- Where
- 5 sites in Denmark, Germany and 1 more
- Volunteers
- 93 people
- Sponsor
- Coloplast A/S
Smoking Cessation
Smoking Cessation for American Indians
American Indians and Alaska Natives (AI/ANs) have the highest smoking rates of the major racial/ethnic groups in the United States, approaching 40% to 50%.1-3 In addition, this underserved population has very low smoking…
- Trial name
- NCT01106456
- Testing
- All Nations Breath of Life (ANBL), Nontailored program (NT), Pharmacotherapy
- Where
- 2 sites in United States
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Won Choi, PhD, MPH
Hypertension, Atrial Fibrillation
Impact of Best Practice Alerts in Cardiology Outpatient Clinics
This quality improvement intervention seeks to implement two Best Practice Alerts (BPAs) for use in cardiology clinics while simultaneously evaluating the impact of each BPA- one for patients with uncontrolled blood pressure and…
- Trial name
- NCT02436421
- Testing
- Best Practice Alert based in the Electronic Medical Record
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Alzheimer's Disease
Alzheimer's Disease Multiple Intervention Trial
The purpose of this study is to conduct a two-year randomized, controlled clinical trial to improve functioning among older adults with Alzheimer's disease by comparing a control group receiving best practices primary care with…
- Trial name
- ADMIT (NCT01314950)
- Testing
- Home based occupational therapy, Best practices primary care
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Indiana University
Colorectal Cancer Screening
Improving Colorectal Cancer Screening for Diverse Hispanics in Urban Primary Care
The proposed study seeks to investigate the impact of a culturally targeted print educational intervention on rates of colorectal cancer (CRC) screening via colonoscopy among Hispanics.
- Trial name
- NCT01569620
- Testing
- Best clinical practices plus culturally targeted print materials, Best clinical practices plus standard print materials, Best clinical practices alone
- Where
- United States
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Varicose Ulcer
Effectiveness and Efficiency of Two Models of Delivering Care to a Chronic Wound Population
Individuals referred to home care for leg ulcer management were randomized to nurse home visits (usual care) or nurse-run community clinics (intervention). The primary outcome will be the time to healing rates at three months.
- Trial name
- NCT00656383
- Testing
- Clients randomized to nurse-led clinic, Clients receive leg ulcer care in their homes
- Where
- 2 sites in Canada
- Volunteers
- 401 people
- Sponsor
- Queen's University
Severe Sepsis
Study of an Electronic Health Record-embedded Severe Sepsis Early Warning Alert
The investigators hypothesize that implementing an electronic health record-based early warning system for severe infections (severe sepsis) will decrease the time to antibiotic order.
- Trial name
- NCT02376842
- Testing
- Severe sepsis early warning best practice alert, Standard care
- Where
- United States
- Volunteers
- 1,149 people
- Sponsor
- Stanford University
WOUNDS
Efficacy Study of Ultrasound-Assisted Debridement to Influence Wound Healing
The UltraHeal Study is a randomized controlled trial to compare healing response of low frequency contact ultrasonic-assisted debridement in addition to best practice wound care to best practice wound care alone in a Vascular…
- Trial name
- UltraHeal (NCT01973361)
- Testing
- Ultrasound debridement, Best practice wound care
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Atrial Fibrillation, Stroke
Left Atrial Appendage Occlusion Study II
A pilot, multicentre randomized controlled study of surgical left atrial occlusion (LAA) in 50 patients with atrial fibrillation/flutter undergoing cardiac surgery requiring cardiopulmonary bypass with additional risk factors for…
- Trial name
- LAAOSII (NCT00908700)
- Testing
- Surgical occlusion of the left atrial appendage, Best medical practice
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- Population Health Research Institute
Tobacco Use Cessation, Second Hand Tobacco Smoke
Families Reduce Exposure to Smoke at Home
This project proposes to evaluate the effectiveness of training Head Start staff to discuss tobacco use, shs reduction and cessation in their existing encounters with parents in reducing tobacco use and exposure.
- Trial name
- FRESH (NCT02557919)
- Testing
- Motivational Interviewing Training, Usual Best Practice
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Diabetes, Hypertension
Audit and Feedback for Primary Care: a Cluster-randomized Trial
In a previous study, the investigators delivered graphs to family physicians that outlined the proportion of patients with a history of diabetes or heart disease achieving evidence-based quality targets derived from guideline…
- Conditions
- Diabetes, Hypertension, Ischemic Heart Disease
- Trial name
- NCT01878370
- Testing
- High risk, Best Practice
- Where
- Canada
- Volunteers
- 177 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pregnancy, Smoking
Smoking Cessation for Low-Income Pregnant Women
To meet the Healthy People 2010 objective of increasing tobacco abstinence among pregnant women to 90%, new methods for treating nicotine addiction among pregnant women are needed.
- Trial name
- ACS (NCT02211430)
- Testing
- Cognitive-Behavioral Counseling (CBC), Best Practice (BC) Control
- Where
- United States
- Volunteers
- 277 people
- Sponsor
- Fox Chase Cancer Center
Tobacco Smoking Behavior
MassCONECT (Massachusetts Community Networks to Eliminate Cancer Disparities Through Education) 4 Kids: Promoting Smoke-free Homes
This study evaluates the effectiveness of a motivational interviewing intervention with families with young children ages 0-5 where smoking is happening in the home to adopt a smoke-free home plan and reduce child's second-hand…
- Trial name
- NCT01537874
- Testing
- Motivational Interview, Usual best practices
- Where
- 3 sites in United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Underperforming Nursing Homes
Improving the Quality of Care in Nursing Homes
The overall goal of this project is to increase the number of high quality nursing homes in Massachusetts. The study will evaluate an intervention involving two active treatment arms: one implementing a CQI program and a second…
- Trial name
- NCT00572221
- Testing
- Continuing Quality Improvement and Quality Assurance system, CQI and QA System with Best-Practice Care Protocols
- Where
- United States
- Volunteers
- 4,316 people
- Sponsor
- Hebrew SeniorLife