Clinical trials: Best Practice
Hearing Loss, Noise-Induced
Does Sound Conditioning Protect Against Temporary Hearing Damage
This research project will contribute to the research surrounding the effect on the ear after noise exposure. This ever-growing field of research has never been more applicable than now with the increase of recreational noise…
- Trial name
- NCT03878875
- Testing
- Session One Test Battery, Session Two Test Battery, Session Three Test Battery
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Asthma
DESOLO - SiT Peri-Launch: A Comparison of Symbicort Single Inhaler Therapy and Conventional Best Practice for the Treatment of Persistent Asthma in Adults
The purpose of this study is to determine whether Symbicort dosed according to the Symbicort Maintenance and Reliever Therapy (SMART) concept is superior to standard asthma treatment according to the local German treatment…
- Trial name
- NCT00252863
- Testing
- Symbicort, used twice daily (b.i.d) and as needed (prn), Budesonide Turbuhaler 200 µg, Fluticasone Discus 250 µg
- Where
- 169 sites in Germany
- Volunteers
- 1,600 people
- Sponsor
- AstraZeneca
Maternal Health, Gender
The Effectiveness of Multi-pronged Interventions to Improve Institutional Delivery in South Ethiopia
This study aims to improve the health and safety of mothers during pregnancy and childbirth by working closely with their husbands.
- Trial name
- NCT07133321
- Testing
- Husband Group Health education., Helping Mothers Survive + RMC
- Where
- Ethiopia
- Volunteers
- 1,680 people
- Sponsor
- Prof Yves Jacquemyn
Esophageal Carcinoma, Lung Carcinoma
Yoga Program for Improving the Quality of Life in Couples Coping With Cancer
This clinical trial seeks to learn if a yoga program can improve physical performance, quality of life and symptom burden in cancer patients who are undergoing radiation therapy, and their partners.
- Conditions
- Esophageal Carcinoma, Lung Carcinoma, Malignant Head and Neck Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04607590
- Testing
- Best Practice, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Stroke
Finger Movement Training After Stroke
Human development as a species has been strongly associated with the ability to dexterously manipulate objects and tools. Unfortunately, current therapy efforts typically fail to restore fine manual control after stroke.
- Trial name
- NCT05621980
- Testing
- Actuated Virtual Keyboard (AVK) system, Occupational Therapy (OT)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- North Carolina State University
Heart Failure With Reduced Ejection Fraction
Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure
An increasing number of guideline-directed medical therapies (GDMT) have been developed for patients with chronic heart failure with reduced ejection fraction (HFrEF).
- Trial name
- IICAPTAIN-HF (NCT06526988)
- Testing
- EPIC-HF Patient-facing Tool, PROMPT-HF Clinician-facing Alert
- Where
- 5 sites in United States
- Volunteers
- 2,200 people
- Sponsor
- University of Colorado, Denver
COVID-19 Vaccine Knowledge, COVID-19 Vaccine Beliefs
Effectiveness of Interactive Voice Response for COVID-19 Vaccination Training in the Democratic Republic of the Congo
This study seeks to evaluate the effectiveness of a remote training course delivered via interactive voice response (IVR) to the mobile phones of frontline providers in the Democratic Republic of the Congo (DRC) during the…
- Trial name
- NCT05107479
- Testing
- COVID-19 Vaccine IVR Training, Control Condition
- Where
- United States
- Volunteers
- 8,959 people, healthy volunteers welcome
- Sponsor
- Stanford University
Lymphoma, Malignant Solid Neoplasm
Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial
This phase III trial compares the effect of geriatric evaluation and management with survivorship health education (GEM-S) to usual care on patient-reported physical function in older survivors of cancer.
- Trial name
- GEM-S (NCT05006482)
- Testing
- Best Practice, Comprehensive Geriatric Assessment, Educational Intervention
- Where
- 45 sites in United States
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Asthma
STYLE - Symbicort Single Inhaler Therapy vs Conventional Therapy in Treatment of Persistent Asthma
The purpose of the study is to compare the efficacy of a flexible dose of Symbicort with conventional stepwise treatment according to asthma treatment guidelines in patients with persistent asthma
- Trial name
- NCT00252824
- Testing
- Budesonide/formoterol Turbuhaler vs Conventional Best Asthma Therapy
- Where
- 53 sites in Chile, Croatia and 8 more
- Volunteers
- 1,000 people
- Sponsor
- AstraZeneca
Stroke Rehabilitation
Mirror Therapy Preceding Augmented Reality in Stroke Rehabilitation
This proposed research is in line with the National Health Research Institutes (NHRI) Innovative Research Grant priority to address innovative treatment strategies for neurological disorders that are in desperate need of…
- Trial name
- NCT05467813
- Testing
- mirror therapy, augmented reality (AR), control therapy
- Where
- 5 sites in Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Implicit Bias
Virtual Implicit Bias Reduction and Neutralization Training (VIBRANT)
Healthcare providers' implicit bias has been identified as a contributor to longstanding health inequities via negative impacts on the patient-clinician relationship and biased delivery of high-quality evidence-based practices…
- Trial name
- VIBRANT (NCT05970991)
- Testing
- Brief Online Training (BOLT) for measurement-based care (MBC), Virtual Implicit Bias Reduction and Neutralization Training (VIBRANT), Live Post-Training Consultation
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Washington
Heart Failure
PRagmatic Trial Of Messaging to Providers About Treatment of Heart Failure at Inova
A randomized, single-blind intervention trial to test the comparative effectiveness of an electronic health record best practice advisory system that informs clinicians of guideline-indicated and FDA-approved heart failure…
- Trial name
- PROMPTHF-Inova (NCT05433220)
- Testing
- Best Practice Advisory using Electronic Health Record
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Inova Health Care Services
Prostate Carcinoma
A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men
This clinical trial tests how well a point of prostate cancer diagnosis (PPCD) virtual reality assistant (ViRA) intervention works in supporting Black men with newly diagnosed prostate cancer.
- Trial name
- NCT07126548
- Testing
- Best Practice, Discussion, Survey Administration
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Breast Cancer Screening, Colorectal Cancer Screening
Improving Cancer Screening and Follow-up in Community Health Centers
This is an implementation science study that examines implementation of a single intervention and the development of practice-level implementation strategies to facilitate implementation of the intervention.
- Conditions
- Breast Cancer Screening, Colorectal Cancer Screening, Implementation
- Trial name
- NCT05756725
- Testing
- Practice-Level Implementation Strategies
- Where
- 3 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Uveal Melanoma
Psychoeducation for Uveal Melanoma
This clinical trial evaluates a video-based psychoeducational intervention for patients with uveal melanoma. Uveal melanoma (UM) is a rare intraocular cancer.
- Trial name
- NCT06075589
- Testing
- Education for Intervention, Best Practice
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Diabetic Foot Ulcer, Non-healing Diabetic Foot Ulcer
EPC Silver Wound Gel (EPC-123) Feasibility Study in the Management of Mildly Infected Diabetic Foot Ulcers
The objective of this single-arm feasibility study is to investigate the safety and impact of the topical EPC Silver Wound Gel (EPC-123) in the management of diabetic foot ulcer wounds not progressing under the current standard…
- Conditions
- Diabetic Foot Ulcer, Non-healing Diabetic Foot Ulcer, Diabetic Foot Infection
- Trial name
- NCT05243810
- Testing
- EPC Silver Wound Gel
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Exciton Technologies Inc.
Climate Change
Atlas:Text Messaging Program With Weather Alerts, Local Resources & Insights for Addressing Climate Change
Climate change is an urgent public health threat, and climate-related health risks disproportionately impact vulnerable populations.
- Trial name
- NCT06995755
- Testing
- atlas
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Pro-Change Behavior Systems
Stage III Pancreatic Cancer, Pancreatic Adenocarcinoma Non-resectable
Malnutrition Screening and Dietary Intervention to Improve Nutrition Outcomes in Patients With Unresectable Pancreatic Cancer
This clinical trial compares the effect of malnutrition screening and dietary intervention to standard nutrition care on patients with pancreatic cancer that cannot be removed by surgery (unresectable).
- Trial name
- NCT06090916
- Testing
- Best Practice, Dietary Intervention, Medical Chart Review
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Gambling
Prevention Messages for EGMs: Effects on Behaviours and Cognitions
The goals of this randomized controlled trial are to test the manifold effects of prevention pop-up messages on participants' behaviours, cognitions and affects.
- Trial name
- NCT06341504
- Testing
- Prevention pop-up messages, Mandatory time limit, Responsible gambling information
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Benjamin Galipeau
Wounds
Cold Plasma Jet kINPen Med Versus Best Practice Wound Dressings
Within the treatment of chronic wounds the main objective is to analyze the wound healing properties with cold plasma (cold plasma jet kINPen® Med) compared to wound phase-adapted best practice wound dressings.
- Trial name
- NCT04965805
- Testing
- cold plasmaJet kINPen Med, Best practice wound dressings
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Federal University Teaching Hospital, Feldkirch, Austria