Clinical trials: Blood sampling, completed
Pharmacologic Action
Genetic Variability in CYP2D6 in U.S Active Duty Population
The investigator proposes to 2D6 (Cytochrome P-450 Isoenzyme 2D6) genotype and phenotype a group of active duty service members and assess the effects on primaquine metabolism.
- Trial name
- NCT02960568
- Testing
- Primaquine
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Parkinson's Disease
Leukine (Sargramostim) for Parkinson's Disease
The purpose of this study is to determine if Leukine (sargramostim) can be safely administered to Parkinson's disease patients for an extended period of time (56 days) and restore immune deficits seen in Parkinson's patients…
- Trial name
- NCT01882010
- Testing
- sargramostim
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Nebraska
Dietary Modification
Antioxidant Responses to Exercise and Cherry Consumption
To date, there are no published studies on the effects of tart cherry consumption on postprandial antioxidant and oxidative stress levels following a high-fat meal.
- Trial name
- NCT03522779
- Testing
- Tart cherry Juice, High-fat meal, Exercise
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Peritoneal Dialysis Associated Peritonitis, Peritoneal Dialysis (PD)
Pharmacokinetics of Meropenem and Aztreonam After Intraperitoneal Administration Via Cycler-therapy in APD Patients Without Peritonitis
Peritoneal dialysis-associated peritonitis (PDAP) remains one of the most serious complications in patients undergoing peritoneal dialysis (PD), contributing significantly to hospitalization, technique failure, and mortality.
- Conditions
- Peritoneal Dialysis Associated Peritonitis, Peritoneal Dialysis (PD), Peritoneal Dialysis, Peritoneal Dialysis, Continuous Ambulatory
- Trial name
- NCT07113574
- Testing
- Meropenem 1000 mg, Aztreonam 2000 mg, automated peritoneal dialysis with following long time dwell
- Where
- Austria
- Volunteers
- 12 people
- Sponsor
- Karl Landsteiner Insitute for Nephrology and Haemato-Oncology
Pulmonary Arterial Hypertension
Biomarkers in the Diagnosis and Assessment of Pulmonary Arterial Hypertension (PAH)
The investigators hypothesize that baseline plasma brain natriuretic peptide (BNP) and migration inhibitory factor (MIF) levels are surrogate markers of clinical severity of PAH and that changes in plasma brain natriuretic…
- Trial name
- Biomarkers (NCT00566423)
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Northwell Health
Invasive Fungal Infections
Interest of ß 1-3 D Glucan Assays in Screening for the Onset of Invasive Aspergillosis in Neutropenic Patients With Acute Leukaemia.
In the context of screening for infectious fungal diseases in patients with malignant haemopathy, and particularly patients with acute leukaemia, the investigator aims to evaluate the performance of an already commercialized but…
- Trial name
- BETA GLUCAN (NCT02851680)
- Testing
- blood samples
- Where
- France
- Volunteers
- 476 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Pulmonary Embolism
Pulmonary Embolism in Pregnancy: Biomarkers and Clinical Predictive Models
Objective: To evaluate whether trimester specific d-dimer levels and brain natriuretic protein (BNP), along with the modified Wells score (MWS), is a useful risk stratification tool to exclude pregnant women at low-risk of…
- Trial name
- NCT02709174
- Testing
- blood draw
- Volunteers
- 59 people
- Sponsor
- Wake Forest University Health Sciences
Poor Ovarian Response
Long-term Endogenous Androgen Priming in Bologna Criteria Poor Responder Patients - A Pilot Study
Until now no scientific clinical evidence exists regarding the possible impact of long term endogenous androgen priming in IVF patients aligned with the Bologna Criteria, in specific the impact of priming on serum parameters…
- Trial name
- NCT03447184
- Testing
- Androgen priming
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- Mỹ Đức Hospital
Asthma, Allergies
Induced Tolerogenic Dendritic Cells as Modulators of Allergic Asthma
Despite advances in medications, allergic diseases, including allergic asthma continue to rise in prevalence. For this reason, there is a need for a better understanding of the mechanisms of allergic diseases and novel insights…
- Trial name
- MGH-002 (NCT01711593)
- Testing
- Bronchoscopy, Segmental Allergen Challenge and Bronchoalveolar Lavage, Phlebotomy
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Andrew D. Luster, M.D.,Ph.D.
Hepatocellular Carcinoma (HCC)
Annexin A2 as a Novel Diagnostic Marker in Hepatocellular Carcinoma
This study aimed to investigate the clinical utility of Annexin A2 serum level as a novel diagnostic marker of hepatocellular carcinoma (HCC) and to correlate its level with alpha fetoprotein the current marker ofhepatocellular…
- Trial name
- NCT02541149
- Testing
- blood sample
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Type 2 Diabetes Mellitus
Telemonitoring System Study in Participants With Type 2 Diabetes Mellitus (MK-0000-347)
The primary goal is to evaluate whether a home telehealth system that enables the participant to monitor their body weight, blood glucose values and blood pressure values, associated with remote educational support and feedback…
- Trial name
- NCT02194608
- Testing
- Home telehealth system
- Volunteers
- 500 people
- Sponsor
- Merck Sharp & Dohme LLC
Raynaud's Phenomenon Isolated Primary, Raynaud's Phenomenon (Secondary)
Identification of TRP Channels as New Potential Therapeutic Targets in Primary and Secondary Raynaud's Phenomenon.
The investigators seek to perform a comparative transcriptome analysis of TRP channels residing in the skin between primary and scleroderma secondary Raynaud's phenomenon and healthy subjects.
- Conditions
- Raynaud's Phenomenon Isolated Primary, Raynaud's Phenomenon (Secondary), Healthy
- Trial name
- TRP (NCT03211325)
- Testing
- Biopsy
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Acute Coronary Syndrome
GALNT4 in Patients With Acute Coronary Syndrome
The expression of GALNT4 in blood with acute coronary syndrome
- Trial name
- NCT03335514
- Testing
- expression of GALNT4
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Pneumonia, Pneumocystis
Specialized Proresolving Mediators in Pneumocystis Jirovecii Pneumonia
This study aims to evaluate specialized proresolving mediators (SPM) concentrations for the first time in subjects infected with Pneumocystis jirovecii.
- Trial name
- INFLA-PCP (NCT03606252)
- Testing
- Blood sampling, urine sampling
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Toulouse
Excess Intake of Macronutrients, Excess Intake of Micronutrients
Water and Coffee Intervention in Humans
39 healthy subjects without medication (except oral contraceptives) aged 20-70 years are recruited via advertisements or through telephone contacts with individuals that had previously participated in population-based cohort…
- Conditions
- Excess Intake of Macronutrients, Excess Intake of Micronutrients, Vasopressin Low
- Trial name
- NCT06165185
- Testing
- Water, Coffee, Control
- Where
- Sweden
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Region Skane
Meningococcal Disease, Meningococcal Meningitis
A Study to Evaluate the Persistence and Immune Response to a Booster Dose of MenACWY
The primary objective is to evaluate the persistence of bactericidal antibodies in adolescent subjects who completed study V59P6 in which they received either Novartis Meningococcal (MenACWY) Conjugate Vaccine or Licensed…
- Trial name
- NCT01018732
- Testing
- Novartis Meningococcal (MenACWY-CRM) vaccine
- Where
- 3 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Insulin Resistance, Proteomics
Proteomics in Morbid Obesity After Bariatric Surgery
Glycemic control is rapidly restored in patients with insulin resistance after bariatric surgery, in particular after the mal-absorptive one (i.e. Bilio-pancreatic diversion, BPD).
- Conditions
- Insulin Resistance, Proteomics, Morbid Obesity
- Trial name
- PROTOBESE (NCT01151917)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Catholic University of the Sacred Heart
Musculoskeletal Pain
Pain Catastrophizing as a Cause for Systemic Inflammation
Research shows that the immune system is involved in chronic pain. The immune system is involved in the process of inflammation.
- Trial name
- NCT00823147
- Testing
- Pain Catastrophizing Induction
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Beth Darnall, PhD
Mild Cognitive Impairment, Alzheimer's Disease
African American Alzheimer's Progression Markers - CSF and Neuro-Imaging
African Americans are twice as likely to develop Alzheimer's disease as white Americans, but few African Americans are enrolled in large Alzheimer's biomarker studies.
- Trial name
- A3PM (NCT02089555)
- Testing
- Lumbar puncture, Blood draw, Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Emory University
Children, Preschool, Pain and Anxiety
Storytelling Caterpillar - Pain, Anxiety, and Satisfaction
This randomized controlled trial aims to evaluate the effect of using the "Storytelling Caterpillar" toy on pain, anxiety, and parental satisfaction during blood draw procedures in children aged 3 to 6 years.
- Trial name
- SC-PAS (NCT07127432)
- Testing
- The Storytelling Caterpillar
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Koç University