Clinical trials: Botulinum toxin type A
Pain
Subcutaneous Botulinum Toxin for Cutaneous Allodynia - Enriched Responder Trial
Superficial injection of Botulinum toxin has been advocated for cosmetic purposes but has also been reported to be helpful for some pain conditions.
- Trial name
- NCT00822926
- Testing
- Botulinum Toxin Type A, Saline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Glabellar Lines
Dysport in the Treatment of Glabellar Lines in Chinese Subjects
The objective of this study is to demonstrate the efficacy of Dysport for the improvement in appearance of moderate to severe glabellar lines and to assess the short term and long term safety of Dysport, used for the improvement…
- Trial name
- NCT02450526
- Testing
- Botulinum toxin type A
- Where
- 10 sites in China
- Volunteers
- 520 people
- Sponsor
- Ipsen
Urinary Bladder, Overactive, Urinary Bladder, Neurogenic
Observational Study of Botulinum Toxin Type A in Patients With Urinary Incontinence Associated With Overactive Bladder
This study will describe the prescription conditions of botulinum toxin Type A (Botox®) injection for the treatment of urinary incontinence due to neurogenic detrusor overactivity (NDO) or idiopathic overactive bladder (IOAB) as…
- Trial name
- BOREAL (NCT02673047)
- Testing
- botulinum toxin Type A
- Where
- 50 sites in France
- Volunteers
- 474 people
- Sponsor
- Allergan
Spasticity
Trial Comparing Two Commercial Formulations of Botulinum Toxin Type A in the Treatment of Spasticity
The purpose of this study is to compare the effectiveness between two commercial formulations of botulinum toxin type A in the treatment of spasticity through the Ashworth scale.
- Trial name
- NCT00819065
- Testing
- Botulinum toxin type A from laboratory Lanzhou, Botulinum toxin type A from laboratory Allergan
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Botulinum Toxins, Type A
Injections of Botulinum Toxin A in Treatment of Patients With Detrusor Overactivity and Impaired Contractility
The objectives of this study is to evaluate and compare the efficacy and safety between 100 U of botulinum toxin A (BoNT-A) suburothelial injections and combined 50 U of BoNT-A suburothelial injections and 50 U urethral injection…
- Trial name
- NCT02135341
- Testing
- Botulinum toxin A
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Pain
The Effect of Music Meditation Therapy in Patients With Chronic Pain Receiving Botox
The purpose of this pilot study is to examine the impact of music meditation therapy session on patients with chronic pain who are receiving Botox injections at a pain management center.
- Trial name
- NCT03532607
- Testing
- Music
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Rowan University
Urinary Incontinence, Urge
Refractory Overactive Bladder: Sacral NEuromodulation v. BoTulinum Toxin Assessment (ROSETTA)
The purpose of this randomized, open-label, active-control trial is to compare the effectiveness of intra-detrusor botulinum toxin A (Botox A®, Allergan) versus sacral neuromodulation (InterStim®, Medtronic) for the treatment of…
- Trial name
- ROSETTA (NCT01502956)
- Testing
- InterStim® device, Botox® injection
- Where
- 9 sites in United States
- Volunteers
- 386 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Chronic Scar Pain
Dysport in Post-Surgical Neuralgia
The study is designed to determine whether a currently licensed version of botulinum toxin (Dysport®) is effective for the treatment of pain that has developed and/or persisted for months or years around the scar of a previous…
- Trial name
- PMOD03 (NCT03663101)
- Testing
- Lidocaine, Botulinum toxin type A
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Ipsen
Raynaud Phenomenon
The Effect of Abobotulinum Toxin A on the Symptoms of Raynaud's Phenomenon
This study aims to investigate the effect of abobotulinum toxin A on the symptoms of Raynaud's phenomenon.
- Trial name
- NCT03639766
- Testing
- AbobotulinumtoxinA, Saline solution
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Achalasia
Botox or Botox With Esophageal Dilation in Patients With Achalasia
Achalasia is a rare esophageal motility disorder. Treatment of achalasia is aimed toward palliation of symptoms. These include botox injections to the lower esophageal sphincter (LES), pneumatic dilation, surgical myotomy, and…
- Trial name
- NCT03654066
- Testing
- Botulinum toxin type A, Endoscope balloon dilator, Patient reported outcomes
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Vanderbilt University Medical Center
Cerebral Palsy, Drooling
Treatment of Drooling With Type A Botulinum Toxin in Children With Cerebral Palsy
The purpose of this study is to evaluate the effectiveness of botulinum toxin injection to treat drooling in children with cerebral palsy, and to find the most appropriate dosage, duration of effect and side effects.
- Trial name
- NCT00173745
- Testing
- botulinum toxin A injection
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Wrinkles
Lateral Canthal Rhytides With Medium Depth Chemical Peel With or Without Pretreatment With Botulinum Toxin A
This study is being done to find out if the use of botulinum toxin prior to a medium strength combination chemical peel (Jessner's peel followed by 35% Trichloroacetic acid peel) will improve the appearance of crow's feet…
- Trial name
- NCT01586819
- Testing
- Botulinum Toxin, Chemical Peel Only
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Loyola University
Glabellar Lines
Safety and Efficacy of CKDB-501B in Subjects With Moderate-to-severe Glabellar Lines
A single-center, randomized, double-blind, single-injection, active-controlled, parallel-design study to evaluate the safety and efficacy of CKDB-501B in Glabellar lines.
- Trial name
- NCT05428930
- Testing
- CKDB-501B, Botox®50U
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CKD Bio Corporation
Cervical Dystonia
A Study to Compare Dysport® and Botox® in the Treatment of Cervical Dystonia
1. to examine the non-inferiority of Dysport in the clinical efficacy and safety in comparison with Botox®, assuming a bioequivalence ratio of 2.5:1 units, in the treatment of Cervical dystonia. 2.
- Trial name
- NCT00950664
- Testing
- Dysport® (abobotulinumtoxinA), Botox® (onabotulinumtoxinA)
- Where
- 7 sites in South Korea
- Volunteers
- 103 people
- Sponsor
- Seoul National University Hospital
Glabellar Frown Lines
The Safety and Efficacy Study of Hutox Versus Botox® in Subject With Moderate to Severe Glabellar Lines
A Phase Ⅲ Clinical Trial to Compare the Safety and Efficacy of Hutox versus Botox® in Subject with Moderate to Severe Glabellar Lines
- Trial name
- NCT03440671
- Testing
- Hutox Inj, Botox Inj
- Where
- South Korea
- Volunteers
- 260 people
- Sponsor
- Huons Co., Ltd.
Cerebral Palsy
The Effect of Botox Injection on Postural Stability of Cerebral Palsy (CP) Children
Children suffer from Cerebral Palsy that willing to participate in the study will be tested with well-established measuring techniques of Balance control using force plate before 2 month after BOTOX injection in the movement and…
- Trial name
- NCT00651339
- Testing
- botox
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Soroka University Medical Center
Migraine
OnaBotulinumtoxin-A in Chronic Migraine Patients With Short or Long Disease History (the BACH Study)
The goal of this observational prospective multicentric study, 12 months duration is to investigate whether the history of Chronic Migraine and, more precisely, its duration for over or less than 10 years, can predict OBT-A…
- Trial name
- BACH (NCT06537700)
- Testing
- OnabotulinumtoxinA OBT-A
- Where
- 6 sites in Italy
- Volunteers
- 115 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Shoulder Pain
The Treatment of Shoulder Pain in Hemiplegic Spastic Patients With Botulinum Toxin A
Stroke is the leading cause of disability in developed countries, and the major cause of mortality in Brazil.It is associated with low quality of life, disability, decreased muscle strength and control due to the hypertonia…
- Trial name
- dolomtox (NCT04470401)
- Testing
- AbobotulinumtoxinA, Saline
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Transfer Dysphagia, Oropharyngeal Dysphagia
Onabotulinum Toxin A (Botox) in the Treatment of Pharyngo-esophageal Dysphagia
Dysphagia in patients with stroke, multiple sclerosis, parkinsonism or dystonia can occur due to relative hypertonia of the cricopharyngeus muscle. In the resting state, muscle is contracted and relaxes only during deglutition.
- Conditions
- Transfer Dysphagia, Oropharyngeal Dysphagia, Cricopharyngeus Muscle Dysfunction
- Trial name
- NCT04695600
- Testing
- Botulinum Toxin Type A Injection [Botox]
- Where
- India
- Volunteers
- 100 people
- Sponsor
- All India Institute of Medical Sciences
Upper Limb Spasticity
Study of Intramuscular Injections of ABBV-950 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Spasticity
Spasticity is often observed as muscle tightness and stiffness in the upper and/or lower limbs. Upper limb spasticity can interfere with joint movement and its severity can range from mild to severe.
- Trial name
- NCT05956509
- Testing
- ABBV-950, BOTOX
- Where
- 9 sites in United States
- Volunteers
- 1 people
- Sponsor
- AbbVie
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