Clinical trials: Botulinum toxin type A, completed
Hemifacial Spasm
Study of Abobotulinum Toxin Versus Neubotulinum Toxin Injection For Hemifacial Spasm in Thai Patients
A 50-Week Prospective, Double-Blinded, Randomized, Cross-over design in Multicenter Study of 100 unit of Abobotulinum Toxin Type A (Dysport®) versus 33.33 unit of Neubotulinum Toxin Type A (Neuronox®) Injection for Hemifacial…
- Trial name
- DNHFS (NCT04589364)
- Testing
- Injection botulinum toxin A ( Dysport 100 unit or Neuronox 33.33 unit)
- Where
- 4 sites in Thailand
- Volunteers
- 107 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Glabellar Frown Lines
Study to Evaluate the Efficacy and Safety of MBA-P01 in Subjects With Glabellar Lines
This study is intended to evaluate the efficacy and safety of MBA-P01 compared to BOTOX in treatment of glabellar lines.
- Trial name
- NCT05059587
- Testing
- MBA-P01, BOTOX
- Where
- South Korea
- Volunteers
- 318 people
- Sponsor
- Medytox Korea
Urinary Incontinence
Study of Botulinum Toxin Type A (BOTOX®) to Treat Urinary Incontinence From Neurogenic Detrusor Overactivity in Belgium
This study will evaluate the impact of BOTOX® treatment on anticholinergic drug use in patients with urinary incontinence from Neurogenic Detrusor Overactivity (NDO) due to spinal injury or Multiple Sclerosis (MS) who are…
- Trial name
- NCT02072928
- Testing
- botulinum toxin Type A
- Where
- 6 sites in Belgium
- Volunteers
- 55 people
- Sponsor
- Allergan
Cerebrovascular Accident, Muscle Spasticity
Effects on Quality of Life Following Dysport Treatment in Post-stroke Spasticity of the Arm
The main purpose of this study is to assess the effect on Quality of Life of two cycles of Dysport treatment on post-stroke spasticity of the upper limb. The effect of treatment on spasticity and function will also be measured.
- Trial name
- NCT00216411
- Testing
- Botulinum toxin type A
- Where
- 6 sites in Australia
- Volunteers
- 96 people
- Sponsor
- Ipsen
Secondary Headache Disorder
The Effect of Botulinum Toxin A on Headache Attributed to TMD
This study will evaluate the effect of of botulinum toxin on the treatment of Headache Attributed to TMD.
- Trial name
- NCT03346252
- Testing
- Botulinum Toxin type A
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- State University of New York at Buffalo
Post-stroke Shoulder Pain and Spasticity
Randomized DB Controlled Trial of Botulinum Toxin A in Hemiplegic Shoulder Pain and Spasticity
The purpose of this study is to evaluate whether botulinum toxin type A injected into muscles around the shoulder is effective in treating shoulder pain and improving function in patients with shoulder pain and involuntary muscle…
- Trial name
- NCT00661089
- Testing
- Botulinum Toxin Type A - OnabotulinumtoxinA
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Shirley Ryan AbilityLab
Cerebral Palsy and Botulinum Toxin
Spread And Effectiveness Of Botulinum Neurotoxin A In Spastic Equinus In Cerebral Palsy
Objectives. To study the short-term neurophysiological and clinical outcome of botulinum toxin type A(BoNT-A), injected at standard doses, and assess toxin spread to neighboring uninjected muscles in children with cerebral palsy.
- Trial name
- NCT01276015
- Testing
- Botulinum Toxin Type A
- Volunteers
- 18 people
- Sponsor
- Universita di Verona
Bruxism
Change in Biting Force After Botox Injection
Implant rehabilitation is a successful treatment option for edentulous patients. Decreasing bone loss around implants is an important target for all implantologists.
- Trial name
- NCT04940104
- Testing
- Botox Injectable Product
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Anal Fissure Chronic
The Efficacy of Botulinum Toxin Alone Versus Combined Botulinum Toxin and Topical Diltiazem in Chronic Anal Fissure
Anal fissure (AF) is a painful tear extending from the anal canal to the dentate line. Although the exact pathophysiology is not known, an increase in anal tonus, decreased ano-dermal blood flow and local ischemia are possible…
- Trial name
- NCT05797220
- Testing
- Botulinum Toxin Type A Injection [Botox], Botulinum Toxin Type A Injection [Botox] + Diltiazem Hydrochloride 20 Mg/G Rectal Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people
- Sponsor
- Istanbul Medipol University Hospital
Bruxism, Myofascial Pain
Ultrasonographic Evaluation of Masseter Muscle Changes After Botulinum Toxin Injection in Bruxism Patients
This prospective pilot study aimed to evaluate short-term clinical and ultrasonographic changes in the masseter muscle following botulinum toxin injection in patients with bruxism.
- Conditions
- Bruxism, Myofascial Pain, Masseter Muscle Hypertrophy
- Trial name
- NCT07545200
- Testing
- Botulinum Toxin A (Botox )
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Convergence Insufficiency, Divergence Insufficiency
A Prospective Observational Study of Adult Strabismus
The purpose of this study is to describe clinical characteristics, treatments, and one-year outcomes of adults with convergence insufficiency, divergence insufficiency, or small angle hypertropia.
- Conditions
- Convergence Insufficiency, Divergence Insufficiency, Hypertropia
- Trial name
- SAS1 (NCT02510040)
- Testing
- Prism, Orthoptic Exercises, Eye Muscle Surgery
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- Jaeb Center for Health Research
Base-of-thumb Osteoarthritis
Efficacy of an Intra-articular Injection of Botulinum Toxin A Associated With Splinting for Base-of-thumb Osteoarthritis
The primary purpose of this study is to determine whether a single ultrasound-guided intra-articular injection of botulinum toxin A associated to splinting is effective in reducing pain at 3 months in base-of-thumb osteoarthritis.
- Trial name
- RHIBOT (NCT03187626)
- Testing
- botulinum toxin A, saline
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Muscle Spasticity
Exploring Advanced Imaging Techniques to Characterize Botulinum Toxin Diffusion in Human Muscle
Since the use of botulinum toxin in treating spasticity has already been proven effective, we are now using magnetic resonance imaging to examine the toxin diffusion within muscle (post injection) in order to determine the…
- Trial name
- NCT01412008
- Testing
- Botox (botulinum toxin)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- New York Presbyterian Hospital