Clinical trials: Botulinum toxin type A
Chronic Migraine
Trip-Tox, Effectiveness of Triptans Before and After Onabotulinumtoxin A Treatment in Chronic Migraine
Observational, longitudinal, prospective, prospective, comparative study of the effectiveness of triptans before and after onabotulintoxin A initiation in a single group of chronic migraine patients.
- Trial name
- NCT04871152
- Testing
- OnabotulinumtoxinA
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Hyperhidrosis
GSK1358820 (Botulinum Toxin A) PhIII DB & OL Study in Patients With Axillary Hyperhidrosis
The primary objective of this study is to demonstrate superiority of single treatment of GSK1358820 (hereinafter, referred to as BOTOX®) over placebo in terms of the efficacy of treatment with BOTOX® 50 U in each axilla (100 U in…
- Trial name
- NCT01128738
- Testing
- GSK1358820
- Where
- 14 sites in Japan
- Volunteers
- 152 people
- Sponsor
- GlaxoSmithKline
Alopecia Areata
Treatment of Alopecia Areata of the Scalp With Intradermal Injections of Botulinum Toxin
The purpose of this study is to examine prospectively the safety and efficacy of Botulinum Toxin A (Botox) injections in the treatment of patients with alopecia areata of the scalp.
- Trial name
- NCT00408798
- Testing
- Intracutaneous injections of Botulinum Toxin A (Botox), 0.1 cc per injection site, which equals 10 units
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Peyronie's Disease
H-22411: BOTOX® for Peyronie's Disease
Peyronie's disease is a condition in which a plaque, or hard lump, forms on the penis. It causes hardened tissue, pain, and an abnormal bending in the penis. These symptoms are more severe during an erection.
- Trial name
- NCT00812838
- Testing
- 100 units of Botulinum Toxin Type A, Preservative free normal saline, 100 units Botulinum Toxin A
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mohit Khera
Overactive Bladder
The Urinary Microbiome in Patients Receiving Intradetrusor Botox Injections
An altered urinary microbiome (UM) may explain the symptoms in overactive bladder (OAB) patients who were previously considered to have "idiopathic" OAB.
- Trial name
- NCT04479709
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- MetroHealth Medical Center
Urinary Bladder, Neurogenic, Multiple Sclerosis
Botulinum Toxin A vs Anticholinergic Treatment of Neurogenic Overactive Bladder in Patients With Multiple Sclerosis
Botulinum toxin type A injections into the detrusor at a dose of 200 units (U) of BOTOX® are a recognized second-line treatment for the treatment of adult neurogenic lower urinary tract disorders.
- Trial name
- SEPTOX (NCT04819360)
- Testing
- VESIcare 10Mg Tablet, Botox 100 UNT Injection
- Where
- Switzerland
- Volunteers
- 1 people
- Sponsor
- Brigitte Schürch
Stroke, Brain Injuries
Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity
The study seeks to compare the effectiveness of three preparations of BOTOX-A® in treating muscle tightness and spasms in the feet and ankles of people with stroke.
- Conditions
- Stroke, Brain Injuries, Spasticity
- Trial name
- NCT00178646
- Testing
- Botox
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- The University of Texas Health Science Center, Houston
Sphenopalatine Block, BOTOX
Sphenopalatine Block Versus BOTOX in Management of Chronic Migraine
This trial compares the efficacy and safety of sphenopalatine ganglion block (SPGB) and intramuscular BOTOX injection in chronic migraine.
- Conditions
- Sphenopalatine Block, BOTOX, Chronic Migraine
- Trial name
- NCT06974617
- Testing
- Sphenopalatine block, Botulinum Toxin Type A
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Hidradenitis Suppurativa, Hyperhidrosis
Targeting Nociceptors in Hidradenitis Suppurativa
This study will build on data from mice and humans implicating TRPV1 nociceptors in the pathogenesis of the type-17 chronic inflammatory skin disease Hidradenitis Suppurativa (HS).
- Trial name
- HS (NCT05403710)
- Testing
- Botulinum toxin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Massachusetts, Worcester
Upper and/or Lower Limb Focal Spasticity
A Study to Review Treatment Outcomes From Treatment With Dysport® Injections in Adults for Upper and/or Lower Limb Focal Spasticity
The aim of this retrospective study is to describe the real-world outcomes with the treatment of adult patients with Dysport® injections for focal upper limb spasticity (ULS) and/or focal lower limb spasticity (LLS) in NHS…
- Trial name
- DYSCOVER (NCT04604379)
- Where
- 3 sites in United Kingdom
- Volunteers
- 123 people
- Sponsor
- Ipsen
Spasmodic Dysphonia
Spasmodic Dysphonia Pain
This study aims to identify adjuvant methods to improve patient comfort during in-office laryngology procedures.
- Trial name
- NCT04648891
- Testing
- Lidocaine, Vibrating wand
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Mayo Clinic
Myofacial Pain Syndrome
The Use of Botulinum Toxin in the Management of Myofascial Pain Syndrome
The objective of this study was to assess the efficacy of Botulinum toxin type (A) (BoNTA) injection in Myofascial pain syndrome management in the terms of duration of function improvement and pain reduction.
- Trial name
- NCT06824324
- Testing
- intramuscular Botulinum Toxin
- Where
- Iraq
- Volunteers
- 14 people
- Sponsor
- Yassir R. Al-khannaq
Lateral Canthal Lines, Crow's Feet
Clinical Trial To Evaluate ANT-1207 In Subjects With Crow's Feet
The purpose of this study is to provide evidence of the safety, tolerance, and efficacy of ANT-1207 in the treatment of Crow's Feet.
- Trial name
- NCT01358695
- Testing
- ANT-1207, Botulinum Toxin, Type A, Botulinum Toxin Type A
- Where
- 6 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Anterios Inc.
Fecal Incontinence
Intra-rectal Botulinum Toxin Injection for Intractable Non-retentive Fecal Incontinence in Children - an Open Label Pilot Study
Background: Fecal Incontinence (FI) is a frustrating and prevalent GI condition with profound social implications and a marked effect on quality of life.
- Trial name
- NCT06785844
- Testing
- Botulinum Toxin A (Botox )
- Where
- Israel
- Volunteers
- 14 people
- Sponsor
- Shaare Zedek Medical Center
Graves Ophthalmopathy
Use of Botox in the Management of Thyroid Related Upper Eyelid Retraction
Currently there are few therapeutic options for the treatment of lid retraction secondary to thyroid orbitopathy (TO) during the active stages of the disease.
- Trial name
- NCT01272414
- Testing
- Botulinum Toxin Type A, Saline injection
- Where
- Canada
- Sponsor
- University of Toronto
Oily Skin
BOTOX® Cosmetic and Skin Health.
This is a two cohort, randomized, double blind, single center study to evaluate the effects of Botox Cosmetic (BTX) on sebum protection.
- Trial name
- NCT05138835
- Testing
- Botox Cosmetic
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Andreas Nikolis
Traumatic Brain Injury
Botulinum Toxin and Saliva Management in Tracheotomised Patients
TITLE A randomised placebo controlled trial to explore the effectiveness of Botulinum Toxin injection at reducing oral secretions and frequency of tracheal suctioning in tracheotomised patients.
- Trial name
- NCT00973999
- Testing
- Botulinum Toxin
- Where
- United Kingdom
- Sponsor
- HCA International Limited
Overactive Bladder
OnabotulinumtoxinA (onaBoNT-A) Versus Oral Oxybutynin ER
Overactive bladder is a condition associated with symptoms of feeling the urge to urinate, urinating often, and may or may not be accompanied by leakage of urine.
- Trial name
- NCT01050114
- Testing
- onaBoNT-A, Oxybutynin ER
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Christopher Patrick Smith
Myofacial Pain Syndromes
Does Botulinum Toxin Type-A Injection an Effective Way of Relieving Pain in Myofascial Pain Syndrome Patients or Not
In this research prilocaine and botulinum toxin (BoNT-A) interventions prospectively compared to find out the effect of BoNT-A injection on myofascial pain syndrome (MPS).
- Trial name
- NCT06899438
- Testing
- Botulinum Toxin A Injection, Prilocaine HCl % 2 injectable solution
- Volunteers
- 38 people
- Sponsor
- Bursa City Hospital
Hyperhidrosis
Hyperhidrosis in Patients With Amputations-Botox
The objective is to establish and evidence base for hyperhidrosis treatment algorithm in amputees.This project will address a problem that has troubled Service members, Veterans, and civilians with amputations for decades…
- Trial name
- NCT03236012
- Testing
- Botulinum Toxin Type A (Botox)
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of Utah
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