Clinical trials: Bupivacaine
Nephrolithiasis
Subcostal TAP Block For Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is a minimally- invasive procedure for removing kidney stones. The small incision of PCNL is performed medially from the posterior axillary line according to stones location.
- Trial name
- NCT03454139
- Testing
- Subcostal transversus abdominis plane block
- Volunteers
- 80 people
- Sponsor
- Istanbul University
Knee Replacement, Total, Knee Replacement Surgery
Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine in Spinal Anaesthesia
Prilocaine numbs you for a shorter time, allowing you to regain movement quicker, which helps you recover faster, start rehab sooner, and feel more satisfied with your treatment overall.
- Trial name
- NCT07329582
- Testing
- prilocaine, Bupivacaine
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Postoperative Pain, IL-1 Beta
Comparison of the Ultrasound Guided Effects of the Erector Spina Plane Block and Quadratus Lumborum Block Methods on Postoperative Analgesia and Plasma Cytokine Levels in Elective Cesarean Operations
Comparison of Two Different Analgesic Techniques for Reducing Postoperative Pain After Cesarean Section
- Trial name
- NCT07901829
- Testing
- QL (quadratus lumborum) block, Erector Spinae Plane Block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Education and Research Hospital
Tramadol - Anesthetics- Child - Circumcision
Tramadol in Penial Block Does it Improve Efficiency of Postoperative Analgesia in Circumcision
After the consent of the local ethics committee and informed consent of the parents, we conducted a prospective randomized, double-blind study, from 30 June 2014 to 31 December 2014, including one to eight year olds, ASA I or II…
- Trial name
- NCT03260439
- Testing
- Tramadol
- Where
- Tunisia
- Volunteers
- 106 people
- Sponsor
- Leila mansali stambouli
Postoperative Pain
Quadratus Lumborum Block for Total Abdominal Hysterectomy
Procedure specific postoperative pain management (PROSPECT) guidelines for abdominal hysterectomy published in 2006 recommended laparoscopic or vaginal hysterectomy as a preferred surgical technique.
- Trial name
- NCT05765318
- Testing
- QLB
- Where
- Serbia
- Volunteers
- 60 people
- Sponsor
- Clinical Center Niš
Pain, Postoperative
Intercostal Nerve Cryoablation for Postoperative Pain Management
The purpose of the study is to assess the efficacy of intercostal nerve cryoablation on the magnitude and duration of postoperative pain control both in patients undergoing thoracoabdominal incisions for the descending or…
- Trial name
- NCT03972397
- Testing
- Intercostal Nerve Cryoablation, Bupivacaine liposomal injectable suspension, Patient-controlled analgesia (PCA)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Post Operative Pain
Comparison of Analgesic Efficacy of Suprainguinal Fascia Iliaca and Quadro-iliac Blocks in Hip Fracture Surgery
This prospective, randomized, double-masked trial compared two ultrasound-guided regional analgesic techniques, suprainguinal fascia iliaca block (SIFI) and quadro-iliac plane block (QIPB), in adults undergoing surgery for hip…
- Trial name
- NCT07546903
- Testing
- Suprainguinal Fascia Iliaca Block, Quadro-Iliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Hitit University
HELLP Syndrome
General Anesthesia Versus Spinal Anesthesia in Patients of HELLP Syndrome
Anesthesia for caesarian section in patients with HELLP syndrome is a challenge. Measures should be taken during caesarian delivery to guard against the maternal and fetal complications associated with HELLP syndrome.
- Trial name
- NCT03111446
- Testing
- Spinal Anesthesia, General Anesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Delirium, Lumbar Radiculopathy
Shaping Anesthetic Techniques to Reduce Post-operative Delirium
The purpose of this study is to determine if light sedation with spinal anesthesia reduces the incidence of delirium compared to receiving general anesthesia during spinal surgery in older adults.
- Conditions
- Delirium, Lumbar Radiculopathy, Lumbar Osteoarthritis, Lumbar Spine Disc Degeneration
- Trial name
- SHARP (NCT03133845)
- Testing
- Light sedation with propofol, Induction with propofol, Maintenance anesthetic using a volatile anesthetic
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- Johns Hopkins University
Analgesia, Cesarean Section Complications
Trans Abdominis Plane (TAP) Block in Patients With Cesarean Section
Objective: To compare Trans Abdominis Plane block in providing post cesarean analgesia with control group, in terms of mean postoperative use of Opioids. Study design: Randomized controlled trial.
- Trial name
- TAP (NCT04809532)
- Testing
- Transverse abdominis plane (TAP) block, Bupivacain, Tramadol
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Armed Forces Hospital, Pakistan
Knee Surgery With Tourniquet
Effect of Spinal or Sevoflurane Anesthesia on Neutrophil Activation During Knee Surgery With Pneumatic Tourniquet
Aim of study : Assessement of neutrophil activation during ischemia reperfusion associated with tourniquet use for total knee arthroplasty.
- Trial name
- NCT03470363
- Testing
- Sevoflurane Volatile Liquid, Bupivacaine / SUFentanil
- Volunteers
- 40 people
- Sponsor
- University of Liege
Knee Surgeries
Dexmedetomidine as an Additive for (Ipack)Block in Knee Surgery
Dexmedetomidine used as an Additive for Ipack Block in Knee Surgery
- Trial name
- NCT07058493
- Testing
- Dexmedetomidine, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Injuries to the Ankle and Foot
Minimum Effective Volume of Lidocaine-Bupivacaine for Subgluteal Block
The aim of this study is to determine the minimum effective volume of LA in 90 % of patients (MEV90) required for US-guided subgluteal sciatic nerve block.
- Trial name
- NCT02571699
- Testing
- Subgluteal Nerve Block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Anesthesia
The Effect of Inferior Alveolar Nerve Block in Fracture Mandibular Surgeries
The aim of the study is to assess the efficacy of adding of pre-emptive inferior alveolar nerve block compared to the conventional systemic intravenous analgesia in controlling perioperative pain in fracture mandibular surgeries.
- Trial name
- NCT06167187
- Testing
- bilateral inferior alveolar nerve block, Ketorolac and fentanyl
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Ain Shams University
Labor and Delivery
Epidural Loading: High Volume, Low Concentration
This prospective, randomized, single blinded control trial will investigate the effects of epidural loading with a high volume, low concentration local anesthetic solution via the epidural needle versus the epidural catheter.
- Trial name
- NCT02803450
- Testing
- Epidural needle, Catheter Administration, Standard of Care Epidural Administration
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University
Scalp Block, Regional Anesthesia
When to Block? Timing of Scalp Block in Craniotomy
This study aims to evaluate the effect of scalp block timing-Group 1 will receive a pre-pinning scalp block, while Group 2 will receive a pre-emergence scalp block.-on postoperative recovery quality in patients undergoing…
- Conditions
- Scalp Block, Regional Anesthesia, Craniotomy Surgery, QoR-40
- Trial name
- NCT07043621
- Testing
- pre-pinning group, pre-emergence Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Clavicle Fracture
Does Liposomal Bupivacaine Provide Improved Pain Management for ORIF of Midshaft Clavicle Fractures?
To determine whether liposomal bupivacaine wound infiltration decreases pain scores and narcotic use when compared to bupivacaine alone after open reduction internal fixation of midshaft clavicle fractures.
- Trial name
- NCT03020563
- Testing
- Liposomal Bupivacaine, Bupivacaine
- Where
- United States
- Sponsor
- University of Minnesota
Osteoarthritis, Knee
Liposomal Bupivacaine Versus Standard of Care in Total Knee Surgery
The purpose of this study is to determine whether liposomal bupivacaine is effective in the management of pain following total knee arthroplasty, as compared to standard of care analgesia.
- Trial name
- NCT02219087
- Testing
- Liposomal bupivacaine, Standard of Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- OhioHealth
Breast Cancer, Postoperative Pain
Comparison of Postoperative Analgesic Efficacy of Two Different Blocks in Modified Radical Mastectomy Surgery
Postoperative pain following modified radical mastectomy remains a significant clinical challenge and may delay recovery, impair patient comfort, and increase opioid consumption.
- Trial name
- mastectomy (NCT07737132)
- Testing
- Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Ultrasound-Guided Serratus Anterior Plane Block (SAPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Pregnancy, Cesarean Section
RCT of Epinephrine (None, 100mcg, and 200mcg) in a Hyperbaric Bupivacaine, Fentanyl and Morphine Spinal in C-sections.
This is a prospective, randomized, double blind study of 75 patients (n=25 for each group) in which epinephrine (100mcg or 200mcg) or normal saline vehicle is added to intrathecal hyperbaric bupivacaine (0.75% bupivacaine…
- Trial name
- NCT03335293
- Testing
- 100 mcg Epinephrine, normal saline, 200 mcg Epinephrine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
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