Clinical trials: Bupivacaine
Subarachnoid Hemorrhage, Headache
Efficacy of Percutaneous SPG Block in Aneurysmal SAH
Researchers are trying to develop alternative means to help patients with headache pain secondary to aneurysmal subarachnoid hemorrhage (bleeding about the brain).
- Trial name
- NCT04331938
- Testing
- Regional anesthetic SPG block-bilateral
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Laparoscopic Cholecystectomy
Retrolaminar Block Versus Intraperitoneal Block for Laparoscopic Cholecystectomy
Although laparoscopic cholecystectomy is a minimally invasive surgery, it causes moderate-severe pain. The aim of this study is to assess the quality of pain relief in patients who will undergo in laparoscopic cholecystectomy…
- Trial name
- NCT05755815
- Testing
- retrolaminar block, Peritoneal block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Cesarean Section
Transversus Abdominis Plane Block Versus Wound Infiltration for Analgesia After Cesarean Delivery
Adequate pain control after cesarean delivery is a major concern both for parturient and for obstetric anesthesiologists, and it usually comprises a combination of systemic and regional techniques.The transversus abdominis plane…
- Trial name
- NCT03498118
- Testing
- 20 mL of bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Aswan University Hospital
Ultrasound Guided Rectus Sheath Block, Pain, Postoperative
Comparison Between Ultra Sound Guided Rectus Sheath Block and Field Block for Midline Hernia Repair
Randomized double blinded controlled clinical trial will be done with a total number of 75 patients will be divided into 3 groups.
- Trial name
- NCT03225313
- Testing
- Bupivacaine Hydrochloride 0.5% Injection Solution_#4, Normal Saline Flush, 0.9% Injectable Solution_#5
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Dexmedetomidine VS Fentanyl as Adjuvants to Epidural Bupivacaine in Patients Undergoing Lumbar Spine Surgeries
Evaluation of the Analgesic Effect of Dexmedetomidine Versus Fentanyl as Adjuvants to Epidural Bupivacaine in Patients Undergoing Lumbar Spine Surgeries
To determine if the epidural route provide an acceptable analgesia in spine surgeries and avoided the need for excessive IV analgesics.
- Trial name
- NCT03463083
- Testing
- Dexmedetomidine, Bupivacaine, Fentanyl
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Morbid
Ultrasound Guided Versus Land-mark Method for Spinal Anesthesia in Super Obesity Parturients
This study will investigate whether an ultrasound-assisted technique is better than a classical land-mark technique to facilitate spinal anesthesia in the sitting position in super obese pregnant women with BMI ≥ 50 who will…
- Trial name
- NCT06410820
- Testing
- Procedure/Surgery: Ultrasound method group, Landmark method group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Labor Pain
Epidural Fentanyl for 2nd Stage Labor Analgesia
This study is being done to investigate if there is more effective pain relief during the latter stages of labor and delivery when epidural fentanyl 100mcg is administered compared to epidural fentanyl 20mcg.
- Trial name
- NCT03120780
- Testing
- Fentanyl 20 mcg, Fentanyl 100 mcg
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Ohio State University
Intraoperative Pain Control
Infraorbital Nerve Block for Endoscopic Transsphenoidal Approach to Remove Pituitary Tumor
Perioperative pain relief during endoscopic transsphenoidal pituitary surgery is generally treated with opioids either morphine sulfate or fentanyl.
- Trial name
- NCT04785222
- Testing
- dexmedetomidine 5 mcg mixed with 0.5% plain bupivacaine
- Volunteers
- 63 people
- Sponsor
- Chiang Mai University
Forearm Surgeries
Midazolam in Supraclavicular Brachial Plexus Block
An effective brachial plexus block (BPB) provides a useful alternative to general anesthesia for upper arm surgery producing complete muscular relaxation.
- Trial name
- NCT03185351
- Testing
- Bupivacaine, Midazolam
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Lens Subluxation
Sutureless Technique for Repositioning and Scleral Fixation of the Capsular Bag - Intraocular Lens Complex With Permanent Use of Iris Retractors
Sutureless technique for repositioning and scleral fixation of the capsular bag-intraocular lens complex with permanent use of iris retractors
- Trial name
- NCT07257172
- Testing
- Sutureless technique for repositioning and scleral fixation of the capsular bag - intraocular lens complex with permanent use of iris retractors
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Military Institute od Medicine National Research Institute
Modified Radical Mastectomy, Breast Cancer
Comparison Between Erector Spinae Plane Block Versus Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy
The goal of this clinical trial is to compare Ultrasound Guided Erector Spinae and Ultrasound Guided Serratus Anterior Plane Block post Modified Radical Mastectomy in adult females.
- Trial name
- FMASUMD66/2025 (NCT06947330)
- Testing
- Unilateral Erector Spinae group, Unilateral Serratus Anterior group
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kholoud Usama
Abdominal Hysterectomy
The Effect of Two Different Analgesic Techniques on Postoperative Recovery Quality
Hysterectomy is one of the most frequently performed surgical procedures after Caesarean section in many countries of the world and involves the removal of the uterine corpus with or without the cervix (total hysterectomy) or…
- Trial name
- NCT06766994
- Testing
- intrathecal morphine, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ataturk University
Post Operative Pain
Quadratus Luborum Block Using Bupivacaine Versus Bupivacaine-Dexamethasone in Laparoscopic Cholecystectomy
The aim of the present study was to compare the effectiveness of transmuscular Quadratus Lumborum block using Bupivacaine versus Bupivacaine- Dexamethasone in providing analgesia in patients undergoing laparoscopic…
- Trial name
- NCT03956966
- Testing
- TQL block with saline, TQL block with Bupivacaine, TQL block with Bupivacaine and dexamethasone
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
Observation of Neuromuscular Block, Disease (or Disorder); Gynecological
Clinical Characteristics of Spinal Levobupivacaine: Hyperbaric Compared With Isobaric Solution
The authors would like to investigate the blocking characteristics, surgical quality and side effects of intrathecal levobupivacaine whether there are any differences between the hyperbaric and the isobaric formulation for…
- Trial name
- NCT01349751
- Testing
- isobaric levobupivacaine, hyperbaric levobupivacaine
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Mahidol University
Regional, Intravenous
Regional and Intravenous Dexamethasone in The Prophylaxis of Rebound Pain After Supraclavicular Block in Upper Limb Surgeries
This study aimed to compare the effect of regional and intravenous Dexamethasone in the prophylaxis of rebound pain after supraclavicular block in upper limb surgeries.
- Conditions
- Regional, Intravenous, Dexamethasone, Prophylaxis
- Trial name
- NCT07074691
- Testing
- Regional Dexamethasone, Intravenous Dexamethasone
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Breast Reconstruction
Pain Study Using Intermittent Bupivacain Injections After Breast Reconstruction With DIEP Flap
patients are given bupivacain intermittent locally on the donor site after brest reconstruction with diep flap. The hypothesis was that this approach will reduce the need for rescue analgetic medication and pain perception within…
- Trial name
- NCT00804674
- Testing
- bupivacain
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Pain, Postoperative Pain
Effect of Sacral Erector Spinae Plane Block on Quality of Recovery After Cesarean Delivery: A Prospective Randomized Controlled Trial
Cesarean delivery is one of the most frequently performed major surgical procedures worldwide. The postcesarean period is characterized by moderate to severe pain, which may adversely affect postoperative recovery, patient…
- Trial name
- NCT07900997
- Testing
- Postoperative Analgesia Protocol
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Intrathecal Dexmedetomidine, Pediatric Cancer Surgery
Intrathecal Dexmedetomidine Versus Fentanyl With Bupivacaine in Children Undergoing Major Abdominal Cancer Surgery
In this study the investigators aim to determine the analgesic effect and side effects of intrathecal fentanyl and dexmedetomidine as adjuvant to local anesthetics in pediatric patients undergoing major abdominal cancer surgeries.
- Trial name
- NCT02861716
- Testing
- Bupivacaine, Fentanyl, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute
Postoperative Pain Management in Video-Assisted Thoracoscopic Surgery
Intrathecal Morphine for Recovery and Outcomes After VATS
This study will compare two different methods of pain management in patients undergoing video-assisted thoracoscopic surgery (VATS).
- Trial name
- IMPROVE-VATS (NCT07231926)
- Testing
- Intrathecal Morphine, Serratus Anterior Plane Block (SAPB) group, Dexmedetomidine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ataturk University
Optimal Volume of Liposomal Bupivacaine
Determination of the Optimal Volume of Liposomal Bupivacaine in Adductor Canal Block for Knee Joint Surgery
Building on Bayesian design methodologies from volume optimization studies of ropivacaine in shoulder surgery, this study pioneers the application of a seamless dose-finding strategy in knee ACB.
- Trial name
- NCT06942689
- Testing
- Perform adductor canal block with liposomal bupivacaine.
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
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