Clinical trials: Bupivacaine
Hip Surgeries
Quadratus Lumborum Block by Paraspinous Sagittal Shift Approach With Different Concentrations Of Bupivacaine in Hip Surgeries
The aim of this study is to evaluate the optimum concentration of bupivacaine in Paraspinous Sagittal Shift Approach for Quadratus Lumborum Block in hip Surgeries
- Trial name
- NCT04628689
- Testing
- quadratus lumborum block by paraspinous sagittal shift approach
- Where
- Egypt
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Pain, Postoperative, Pain, Acute
Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement
The purpose of this study is to determine whether administration of a pectoral nerve blocks (Pecs I and II) with 0.25% bupivacaine are more effective as compared to placebo to provide analgesia for cardiac implantable electronic…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chest, Pain
- Trial name
- NCT05283980
- Testing
- 0.25% Bupivacaine
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Craniotomy Surgery, Regional Anaesthesia
A Comparative Analysis of Combined Superficial Cervical Plexus and Supraorbital Blocks Compared to Scalp Blocks During Craniotomy: a Review of Opioid Consumption and The Suppression of Hemodynamic Responses
Perioperative pain management in craniotomy requires the administration of effective regional anesthetic techniques to reduce the use of systemic opioids and optimize hemodynamic control.
- Conditions
- Craniotomy Surgery, Regional Anaesthesia, Scalp Block, Plexus Block;Analgesia;Neurosurgery
- Trial name
- NCT07131046
- Testing
- Combination of superficial cervical plexus block and supraorbital block, Scalp block with bupivacaine alone
- Where
- Indonesia
- Volunteers
- 41 people
- Sponsor
- Universitas Indonesia
Cesarean Section
TAP Block With Intrathecal Fentanyl vs. Intrathecal Morphine in Cesarean Delivery
This noninferiority study aims to determine whether transversus abdominis plane (TAP) block with intrathecal fentanyl could provide a noninferior analgesia compared with intrathecal morphine after cesarean delivery under spinal…
- Trial name
- NCT04824274
- Testing
- fentanyl, morphine, Transversus abdominis plane block
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Laparoscopic Cholecystectomy
Dexamethasone-Enhanced TAP Block in Lapchole
The transversus abdominis plane (TAP) block is widely used as part of analgesia for abdominal surgeries such as laparoscopic cholecystectomy. While bupivacaine is commonly used for TAP blocks with reported success.
- Trial name
- NCT07182110
- Testing
- Dexamethasone enhanced TAP Block, Marcaine- 0.25%
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Hypotension, Anesthesia, Local
The Relationship Between Abdominal Circumference: Hip Ratio and Ephedrine Requirement
This prospective observational study aimed to investigate whether there is a relationship between weight, height, BMI, abdominal circumference (AC), hip circumference (HC), and AC-to-hip ratio with the incidence of hypotension in…
- Conditions
- Hypotension, Anesthesia, Local, Cesarean Section Complications
- Trial name
- NCT05382624
- Testing
- Abdominal circumference was measured at the umbilical level in the standing position at the end of a normal expiration.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Femur Fracture, Peripheral Nerve Block
Peripheral Nerve Blocks vs Selective Spinal Anesthesia in Patients With Femur Fracture
Proximal Femur Fractures (PFF) represent one of the most common orthopedic injuries worldwide, affecting especially elderly patients with potentially disabling outcomes and a marked impairment of quality of life.
- Conditions
- Femur Fracture, Peripheral Nerve Block, Spinal Anesthesia
- Trial name
- NCT06155903
- Testing
- Selective Spinal Anesthesia, Peripheral nerve blocks, Anesthesiological mixtures (Spinal anesthesia)
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Federico II University
Analgesia
Intra-Articular Morphine Versus Bupivacaine on Knee Motion in Patients With Osteoarthritis
CONTEXT AND OBJECTIVE: Osteoarthritis causes pain and disability in a high percentage of elderly people. The aim of the present study was to compare the analgesic effect of intra-articular bupivacaine and morphine in patients…
- Trial name
- NCT00636415
- Testing
- morphine
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Prostate Cancer (Diagnosis), Prostate-Specific Antigen
Intraprostatic Anesthesia During Transperineal Prostate Biopsy
Transperineal prostate biopsy has become the standard method for diagnosing prostate cancer because of its favorable safety profile and low infectious complication rates.
- Trial name
- PRO-PAIN (NCT07683182)
- Testing
- Prilocaine, Bupivacaine, Perineal Local Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Marmara University
Spinal Bupivacaine/Morphine in Laparoscopic Surgery
Spinal Bupivacaine/Morphine in Laparoscopic Gastro-intestinal Surgery
The objective of this study is to determine if a single spinal shot of morphine can decrease post-operative opioid-use, and thereby decrease opioid side-effects and lead to a quicker recovery after surgery.
- Trial name
- Salmon (NCT02284282)
- Testing
- Spinal injection bupivacaine/morphine, subcutaneum injection lidocaine
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- Maasstad Hospital
Hypotension
Decision Support for Intraoperative Low Blood Pressure
The purpose of this study is to determine whether a decision support system can improve the adherence to thresholds for low blood pressure by anesthesia providers, which in turn prevents their patients from having organ injury.
- Trial name
- NCT02726620
- Testing
- Attending real-time decision support, In-room real-time decision support, Attending feedback emails
- Where
- United States
- Volunteers
- 22,435 people
- Sponsor
- Vanderbilt University Medical Center
Cardiac Disease Minimally Invasive Cardiac Surgery Postoperative Pain
Fast-Track Anesthesia in Minimally Invasive Cardiac Surgery: Dexmedetomidine and Erector Spinae Plane Block vs Opioid-Based Anesthesia
Enhanced Recovery After Surgery (ERAS) protocols have revolutionized perioperative management by implementing evidence-based, patient-centered strategies that improve clinical outcomes, shorten hospital length of stay, and reduce…
- Trial name
- Esp (NCT07749274)
- Testing
- Dexmedetomidine, Ultrasound-Guided Bilateral Erector Spinae Plane Block (ESPB), Fentanyl
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Kidney Injury
Serratus-intercostal Plane Block Versus Quadratus Lumborum Block in Nephrectomy: Randomized Study
Performing the nephrectomy by laparoscopy has decrease the incidence of postoperative pain, but there are still some patients who describe a severe pain after this surgery.
- Trial name
- NCT04431388
- Testing
- ultrasound device, Levobupivacaine
- Where
- Spain
- Volunteers
- 126 people
- Sponsor
- Hospital Medina del Campo
Lower Limb Surgeries
Epidural Nalbuphine Versus Dexmedetomidine as Adjuvants to Bupivacaine in Lower Limb Surgeries
Combined spinal epidural anesthesia (CSE) with bupivacaine alone is not sufficient to cover pain sequel during lower limb surgeries.
- Trial name
- NCT05041270
- Testing
- normal saline, Dexmedetomidine, Nalbuphine
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Zagazig University
Pain, Postoperative, Thoracic Surgery, Video-Assisted
Comparison of Erector Spinae Plane Block and Combination of Deep and Superficial Serratus Anterior Plane Block
Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS.
- Conditions
- Pain, Postoperative, Thoracic Surgery, Video-Assisted, Erector Spinae Plane Block, Serratus Anterior Plane Block
- Trial name
- NCT05121727
- Testing
- Erector Spinae Plane Block, Deep and Superficial Serratus Anterior Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Post Operative Pain
Ketamine and Dexmedetomidine Comparative Study
In this study, the investigators will compare the effect of adding ketamine and dexmedetomidine to bupivacaine in US-guided combined sciatic and femoral nerve blocks as regards the onset and duration of the block, postoperative…
- Trial name
- NCT06032624
- Testing
- combined ultra-sound guided femoral and sciatic nerve block.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Osteoarthritis, Knee, Knee Injuries
Motor-Sparing Femoral Nerve Block Dose
Femoral nerve blocks are commonly used to provide pain control for total knee replacement, anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT02909257
- Testing
- Same Bupivacaine Concentration, Lower Bupivacaine Concentration
- Where
- Chile
- Volunteers
- 31 people
- Sponsor
- University of Chile
Postoperative Pain, Regional Anesthesia
Comparison of Continuous Fascia Iliaca Compartment Block With Continuous PENG Block in Total Hip Replacement Cases
Adequate pain management after total hip arthroplasty (THA) is crucial for early ambulation and patient satisfaction. However, due to the hip joint's innervation complexity, the optimal regional analgesia technique for THA…
- Conditions
- Postoperative Pain, Regional Anesthesia, Pain Management, Total Hip Arthroplasty
- Trial name
- PENG (NCT06806865)
- Testing
- Periarticular nerve group block (PENG), Continuous supra-inguinal fascia iliaca compartment block (SIFICB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Post Operative Analgesia
Effect of Intraperitoneal Bupivacaine with Dexmedotomidine or Fentanyl for Post-Operative Analgesia Following Laparoscopy in Pediatric Patients
To compare analgesic effect of adding dexmedomedin or fentanyl to intraperitoneal bupivacain in pediatric patients undergoing laparoscopy.
- Trial name
- NCT06694207
- Testing
- Intraperitoneal Bupivacaine with Dexmedotomidine or Fentanyl
- Volunteers
- 80 people
- Sponsor
- Assiut University
Chronic Knee Joint Osteoarthritis
Saphenous Nerve Block Versus Platelet Rich Plasma for Chronic Knee Osteoarthritis
Knee osteoarthritis, as a progressive disease is one of the most common causes of pain, motor disorder and disability in the elderly.
- Trial name
- NCT03326544
- Testing
- Saphenous nerve block group, Platelet rich plasma group
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Mansoura University
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