Clinical trials: Bupivacaine
Postoperative Pain, Shoulder Arthoscopy
SPSIPB vs CCB in Arthroscopic Shoulder Surgeries
The aim is to compare the postoperative analgesic and hemidiaphragmatic effects of Serratus Posterior Superior Intercostal Plane Block (SPSIPB) versus CostoClavicular Brachial Plexus Block (CCBPB) in patients undergoing…
- Trial name
- NCT07259785
- Testing
- Serratus posterior superior intercostal plane block, Costoclavicular brachial plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Cumhuriyet University
Dexmedetomidine, External Oblique Intercostal Plane Block
Different Doses of Dexmedetomidine in External Oblique Intercostal Plane Block in Splenectomy
The aim of this study is to compare the analgesic effects of different doses of dexmedetomidine as an adjuvant in external oblique intercostal plane block (EOIPB) in splenectomy.
- Conditions
- Dexmedetomidine, External Oblique Intercostal Plane Block, Splenectomy
- Trial name
- NCT06363578
- Testing
- Dexmedetomidine 0.5 μg/kg, Dexmedetomidine 1 μg/kg
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Pain, Postoperative
Pre-emptive Local Anaesthesia in Gynecological Laparoscopy
Pre-emptive local anaesthetics are widely used in laparoscopic surgery, but there is no really consistent evidence that it is useful. Studies in the literature have shown contradicting results.
- Trial name
- NCT01677143
- Testing
- Bupivacaine 5mg/ml
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Analgesia, Patient-Controlled, Epidural Analgesia
Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery.
The purpose of this study is to determine which postoperative analgesia is optimal after colorectal surgery. The investigators will compare intrathecal morphine, continuous epidural analgesia and standard systemic analgesia.
- Conditions
- Analgesia, Patient-Controlled, Epidural Analgesia, Anesthesia; Spinal, Morphine
- Trial name
- KOLORIT (NCT03007121)
- Testing
- Morphine intrathecal, Bupivacaine + Sufentanil epidural, Morphine intravenous
- Where
- Czechia
- Volunteers
- 75 people
- Sponsor
- Charles University, Czech Republic
Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty
Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients
The purpose of this trial is to compare the difference in the proportion of patients with tolerable pain scores, VAS pain scores, quality of recovery and opioid use in milligram equivalents (at 24, 48, 72, 96 and 120 hours…
- Trial name
- NCT05900427
- Testing
- Liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Johnny K. Lee
Spinal Anaesthetic Poisoning, Spinal Anaesthesia
Suprainguinal Facia Iliaca Block in Maximizing the Feasibility of Positioning for Spinal Anesthesia
In this study, we assessed the effect of suprainguinal facia iliaca block in maximizing the feasibility of positioning for spinal anaesthesia in patients with hip and proximal femur fractures by determining the angle that could…
- Trial name
- NCT07594366
- Testing
- Bubpivacaine, Normal Saline
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Pain
Effects of Continuous Nerve Block vs Single Injection Block With PCA vs PCA on Pain and Function After Knee Replacement
The purpose of this study is to compare the effectiveness of three analgesia techniques on pain relief and functional recovery after knee replacement: continuous femoral nerve block vs single-injection femoral nerve block with…
- Trial name
- PCA (NCT01187537)
- Testing
- Continuous Femoral Nerve Block
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- Tan Tock Seng Hospital
Full-thickness Rotator Cuff Tear, Rotator Cuff Tendinitis
Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections
The purpose of this study is to compare the functional outcomes of patients with shoulder pathology treated with either ketorolac or corticosteroid injections, in a randomized double-blinded study.
- Trial name
- NCT04895280
- Testing
- Ketorolac, Marcaine, Kenalog
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Michael Khazzam
Prostate Disease, Malignancy
Self-Administered Nitrous Oxide (SANO) During Transrectal Prostate Biopsy to Reduce Patient Anxiety and Pain
Transrectal prostate biopsy is a commonly performed ambulatory procedure for diagnosing prostate cancer. Prostate biopsy are associated with pain or anxiety.
- Conditions
- Prostate Disease, Malignancy, Benign Prostatic Hyperplasia, Prostate Cancer
- Trial name
- NCT05803096
- Testing
- Self-Administered Nitrous Oxide, Oxygen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Rotator Cuff Tear
The Effect of EXPAREL® on Postsurgical Pain, and the Use of Narcotics
Patients undergoing shoulder rotator cuff surgery in an outpatient setting are the focus of this study. The purpose of this study is to determine if the product EXPAREL® can be used as a safe alternative in shoulder surgery to…
- Trial name
- NCT03290196
- Testing
- EXPAREL 1.3 % in 20 ML Injection
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Andrews Research & Education Foundation
Spinal Decompression, Analgesia
Erector Spinae Block Vs Ketamine-based Multimodal Analgesia Protocol in Lumber Decompressive Surgery
The aim of this study is to compare the quality of recovery of the erector spinae plane block (ESPB) versus ketamine-based multimodal analgesia regimen after spine decompressive surgery.
- Conditions
- Spinal Decompression, Analgesia, Erector Spinae Plane Block, Ketamine
- Trial name
- NCT07001605
- Testing
- ketamine, Erector Spinae Plane Block, Wound infiltration
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Kasr El Aini Hospital
Labor Pain
Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor 2
Brief Summary: Until recently, at Mount Sinai Hospital, epidural analgesia for labor pain was delivered with a pump that could only provide continuous infusion of the freezing medication in combination of pushes of medication…
- Trial name
- NCT02758405
- Testing
- Bupivacaine, Fentanyl, Infusion pump
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Osteoarthritis, Knee
Human Growth Hormone Injections in the Knee Joint to Treat Osteoarthritis
The goal of this clinical trial is to learn if growth hormone injections can be used to treat osteoarthritis (OA) in the knee. Human studies have shown that repeated injections of human growth hormone leads to the production of…
- Trial name
- NCT06354023
- Testing
- Recombinant human growth hormone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- John Sledge
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Vulvodynia, Vestibulodynia
Effects of Flourish HEC on Localized Provoked Vulvodynia
This study is designed to determine whether improving the vaginal microbiome in women with localized provoked vulvodynia (LPV) may help improve pain better than routine care alone.
- Conditions
- Vulvodynia, Vestibulodynia, Vulvar Diseases, Vulvar Vestibulitis
- Trial name
- NCT05478746
- Testing
- BioNourish, a component of the Flourish HEC kit, Control - no intervention
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Vaginal Biome Science
Pain, Postoperative
Parasternal Subpectoral Plane Blocks for Cardiac Surgery Via a Midline Sternotomy
To better determine whether parasternal subpectoral plane blocks (PSPB) infusing bupivacaine for midline sternotomy decreases opioid consumption and pain scores.
- Trial name
- NCT04788056
- Testing
- Parasternal Subpectoral Plane Block
- Sponsor
- Brigham and Women's Hospital
Breast Cancer
Ultrasound Guided Serratus Anterior Plane Block Versus Ultrasound Guided Thoracic Epidural Analgesia
Regional/local analgesic techniques are an important component of a multimodal analgesic strategy, with the aim of reducing opioid requirements and opioid-related adverse events.
- Trial name
- NCT07807605
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Beni-Suef University
Anaesthesia, Toxicity
Sensitivity of ECG on Detection of Three Different Intravascular Applied Test Doses of Bupivacaine and Epinephrine
The purpose of this prospective randomised study is to investigate electrocardiographic alterations after intravascular injection of three different test solutions of bupivacaine and epinephrine in anaesthetised children up to 16…
- Trial name
- NCT01091766
- Testing
- intravenous injection of test solution
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Labor Pain, Labor; Prolonged, Second Stage
Remifentanil vs. Combined Spinal-epidural Analgesia for Labor Analgesia and Progress of Labor in Multiparous
Remifentanil may be an ideal drug for labor analgesia due to its pharmacodynamic and pharmacokinetic profile. As compared to epidural analgesia, it demonstrated satisfactory for pain relief at the beginning of labour with a…
- Conditions
- Labor Pain, Labor; Prolonged, Second Stage, Labor; Prolonged, First Stage
- Trial name
- NCT02963337
- Testing
- remifentanil, combined spinal-epidural analgesia
- Where
- Slovenia
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Uterine Artery Embolization for Uterine Leiomyomata
Patient-Controlled Epidural Analgesia After Uterine Artery Embolization
Uterine artery embolization (UAE) is commonly used to treat symptomatic uterine leiomyomata through induction of infarction and subsequent hyaline degeneration.
- Trial name
- NCT02236585
- Testing
- Patient-controlled epidural analgesia, Continuous epidural analgesia
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
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