Clinical trials: Bupivacaine
Post Operative Pain
Hypobaric Spinal or Hyperbaric in Partial Hip Arthroplasty
The aim of this study was to compare the effects of hypobaric and hyperbaric spinal applications on patient haemodynamics, duration of anaesthetic effect and postoperative analgesia.
- Trial name
- NCT06417203
- Testing
- spinal anesthesia with hyberbaric bupivacaine, spinal anesthesia with hypobaric bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Adiyaman University Research Hospital
Thyroid Cancer, Goiter
Superficial Cervical Plexus Block With Dexmedetomidine Versus Without Adjuvant in Thyroid Surgery
Efficacy of Superficial Cervical Plexus Block (SCPB) with Dexmedetomidine Adjuvant Compared to Without Adjuvant in Thyroid Surgery.
- Conditions
- Thyroid Cancer, Goiter, Hyperthyroidism
- Trial name
- BPSS-DEX (NCT07274670)
- Testing
- Dexmedetomidine & Bupivacaine., Bupivacain
- Where
- Indonesia
- Volunteers
- 58 people
- Sponsor
- Udayana University
Anesthesia, Local
Intralipid® 20% for Reversal of Local Anesthetics
In order to determine if Intralipid 20% can be used to reverse the effects of local anesthetics, the investigators will recruit 18 volunteers who will be asked to come to HSS for two study visits.
- Trial name
- NCT03968822
- Testing
- Lidocaine 2%, Lidocaine 1%, Bupivacaine 0.25%
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Postoperative Pain Management, Laparoscopic Hysterectomy
Intrathecal Morphine Versus Trocar-Site and Intraperitoneal Bupivacaine for Quality of Recovery After Laparoscopic Hysterectomy
This study aims to compare the effects of intrathecal morphine with trocar-site infiltration and intraperitoneal bupivacaine on postoperative pain control, quality of recovery, and inflammatory response in patients undergoing…
- Conditions
- Postoperative Pain Management, Laparoscopic Hysterectomy, Postoperative Recovery
- Trial name
- ITM-LH-QoR (NCT07232108)
- Testing
- Intrathecal Morphine, Trocar-Site Bupivacaine Infiltration, Intraperitoneal Bupivacaine spray
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ataturk University
Hip Osteoarthritis, Osteonecrosis of the Femoral Head
Comparison of the Efficacy of Pericapsular Nerve Group Block Alone Versus Pericapsular Nerve Group Block Combined With Superior Cluneal and Superior Gluteal Nerve Blocks in Patients Undergoing Hip Surgery
In the clinic, total hip arthroplasty is a frequently performed surgical procedure that often results in moderate to severe postoperative pain.
- Conditions
- Hip Osteoarthritis, Osteonecrosis of the Femoral Head, Avascular Necrosis of Femur Head, Dysplasia of Hip Joint
- Trial name
- NCT07255768
- Testing
- 15 ml Bupivacaine Hcl 0.25% injection, 20 mL bupivacaine 0.25% injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Fast Track Surgery
Unilateral Intrathecal Bupivacaine Versus Prilocaine on Postoperative Spontaneous Voiding
Background: In the context of day-case surgery, the optimal spinal anesthetic should give immediate and effective anesthesia for an appropriate period, followed by rapid regression of sensory and motor blocking, rapid bladder…
- Trial name
- NCT07262398
- Testing
- Prilocaine, Bupivacain
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Theodor Bilharz Research Institute
Laryngeal Dystonia, Spasmodic Dysphonia
Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor
The researchers will examine functional neural correlates that differentiate between laryngeal dystonia and voice tremor and contribute to disorder-specific pathophysiology using a cross-disciplinary approach of multimodal brain…
- Conditions
- Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
- Trial name
- NCT05216770
- Testing
- Brain imaging, Laryngeal sensory block with topical bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Arthroscopic Shoulder Surgeries
Effect of Clonidine Additive to suprascapular_ Costoclavicular Versus Standard Interscalene Block in Arthroscopic Shoulder Surgeries
Postoperative analgesia for shoulder surgery is typically achieved by providing an interscalene brachial plexus block. However, a very common side effect of this block is hemi-diaphragmatic paralysis, a state which may not be…
- Trial name
- NCT07256938
- Testing
- Bupivacaine 0.5% (hyperbaric), US-guided costoclavicular block, Interscalene brachial plexus block
- Volunteers
- 60 people
- Sponsor
- Assiut University
Urine Output Decreased
Hemodynamic Determinants of Urine Output During Spinal Anesthesia
This clinical trial investigates the relationship between urine output and mean arterial pressure (MAP) during spinal anesthesia.
- Trial name
- NCT06814561
- Testing
- Marcaine 0.5% Solution for Injection
- Where
- Romania
- Volunteers
- 30 people
- Sponsor
- Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu
Postoperative Pain Management, Cholecystectomy, Laparoscopic
Analgesic Efficacy of Bupivacaine Infiltration, Erector Spinae Plane Block, and Intrathecal Morphine in Laparoscopic Cholecystectomy
This study is designed to compare three different methods of pain control after laparoscopic gallbladder surgery (laparoscopic cholecystectomy).
- Trial name
- ITM-ESP-IPLA (NCT07203794)
- Testing
- Bupivacaine Infiltration, Erector Spinae Plane Block, Intrathecal Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Ataturk University
Pain, Postoperative, Analgesic Effect
Analgesic Efficacy of Different Liposomal Bupivacaine Doses in the Adductor Canal Block for Total Knee Arthroplasty
Total knee arthroplasty is a commonly performed orthopaedic surgery for the treatment of end-stage osteoarthritis when conservative management becomes ineffective.
- Conditions
- Pain, Postoperative, Analgesic Effect, Total Knee Arthroplasty, Liposomal Bupivacaine
- Trial name
- NCT06740214
- Testing
- 0.5% standard bupivacaine only, 1.33% liposomal bupivacaine with 0.5% standard bupivacaine, 1.33% liposomal bupivacaine only
- Where
- Hong Kong
- Volunteers
- 177 people
- Sponsor
- The University of Hong Kong
Liposomal Bupivacaine, Microvascular Decompression
Effect of Local Infiltration of Liposomal Bupivacaine on Postoperative Analgesia in Patients With Craniotomy Microvascular Decompression
Background: Approximately 60-84% of patients undergoing craniotomy experience moderate to severe pain within 48 hours postoperatively, with posterior fossa craniotomy patients experiencing more severe pain.
- Trial name
- NCT07245290
- Testing
- liposomal bupivacaine local infiltration, normal operation
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Erector Spinae Plane Block, Super Obese Patients
The Efficacy of Thoracic Erector Spinae Plane Block For Perioperative Analgesia in Laparoscopic Bariatric Surgery for Super Obese Patients.
The epidemic of overweight and obesity presents a major challenge to chronic disease prevention and health across the life course around the world.
- Conditions
- Erector Spinae Plane Block, Super Obese Patients, Bariatric Surgery
- Trial name
- NCT06377605
- Testing
- ESPB, local anaesthetic infiltration, midazolam and lidocaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Amany Ahmed Eissa
Pregnancy Complications
Use of Propofol as a Sedative Agent Versus Spinal Analgesia With Bupivacaine in External Cephalic Version
External Cephalic Version (ECV) is a maneuver to modify fetal position in pregnant women with a non-cephalic presentation. Its objective is to achieve a cephalic presentation that allows for vaginal delivery with less risk than a…
- Trial name
- PropoSpinECV (NCT06449430)
- Testing
- Sedation with propofol, Spinal analgesia with bupivacaine
- Where
- Spain
- Volunteers
- 270 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Prostate Cancer Surgery
Spinal Anesthesia for Robotic Assisted Laparoscopic Prostatectomy
The investigators hypothesised that spinal anesthesia as an adjunct to general anesthesia would facilitate faster recovery and less pain in patients undergoing laparoscopic robotic prostatectomy.
- Trial name
- NCT06860893
- Testing
- Spinal Anesthesia with Bupivacaine
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- University Hospital of North Norway
Pain After Surgery
Effect of the Superficial Cervical Plexus Block in the Hypotensive Anesthesia of Ear Surgery.
We aimed to evaluate the analgesic effect of ultrasound guided Superficial cervical plexux block in tympanomastoid ear surgeries by comparing it with conventional general anaesthesia using systemic analgesic through observation…
- Trial name
- NCT07241364
- Testing
- nerve block with bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Ain Shams University
Aortic Valve Stenosis, Aortic Diseases
PENG Block forTranscatheter Aortic Valve Implantation
Pericapsular nerve group (PENG block) is a new fascial block defined by Arango et al. This block aims to block the femoral nerve and the accessory obturator nerve by injecting local anesthetic between the pubic ramus and psoas…
- Trial name
- NCT05904912
- Testing
- Postoperative analgesia management, PENG-Bupivacaine, Local infiltration-Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Anesthesia, Anesthesia, Local
Hypobaric L5-S1 Study
Patients going through total hip or knee replacement (arthroplasty) have to be put under spinal anesthesia to prevent them from feeling any pain during surgery.
- Trial name
- NCT06526156
- Testing
- Bupivacaine injection
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University Health Network, Toronto
Maxillofacial Surgeries
Evaluating the Analgesic Efficacy of Superficial Cervical Plexus Block for Maxillofacial Surgeries
The superficial cervical plexus (SCP) originates from the anterior rami of C1-C4 and gives four cutaneous branches supplying the anterolateral neck, external ear, and shoulder tip (1).
- Trial name
- NCT07236086
- Testing
- superficial cervical plexus nerve block, Saline (0.9% NaCl), Bupivacaine
- Volunteers
- 70 people
- Sponsor
- Assiut University
Intraoperative Blood Loss, Pediatric
Tranexamic Acid in Pediatric Undergoing Proximal Femoral Osteotomies and/or Acetabular Osteotomy
Surgical hip reconstruction reduces the hip joint through soft tissue releases and osteotomies of the femur and/or pelvis. Blood loss and subsequent blood transfusion are normal consequences of hip reconstruction.
- Conditions
- Intraoperative Blood Loss, Pediatric, Orthopedic Disorder
- Trial name
- NCT04811313
- Testing
- Tranexamic acid, caudal epidural block
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Assiut University