Clinical trials: Bupivacaine
Pain, Acute Postoperative
Erector Spinae Plane Block Versus Thoracic Paravertebral Block in Laparoscopic Cholecystectomy
The study is planned as a single-center prospective randomized study and includes patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT07149584
- Testing
- ESPB, TPVB, IV
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University
Postoperative Cognitive Dysfunction
The Effect of Intraoperative Hypotension on Postoperative Cognitive Functions in Cesarean Section Operations
The aim of the study is to see whether the hypotension that develops during spinal anesthesia in cesarean section patients causes a decrease in the postoperative cognitive functions of the patient.
- Trial name
- NCT05843838
- Testing
- Hypotension during spinal anesthesia for cesarean section, Mini-mental test, Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Pain, Postoperative
Different Bupivacaine Volumes in Infiltration Between Popliteal Artery and Capsule of Knee Block
comparing between three different volumes; 15, 20 \& 25 ml of 0.25% bupivacaine to determine the best volume of Infiltration Between Popliteal Artery and Capsule of Knee (IPACK) block following adductor canal block (ACB) with the…
- Trial name
- NCT05438992
- Testing
- Bupivacaine 0.25% Preservative-Free Injectable Solution
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Cairo University
Knee Osteoarthritis
Psoas Sciatic Blockade for Knee Arthroplasty
Objectives: To compare the efficacy of continuous combined psoas sciatic block as a sole anaesthetic technique with conventional combined spinal epidural anesthesia for patients undergoing total knee arthroplasty.
- Trial name
- NCT03088371
- Testing
- Bupivacaine 0.25%, Pajunk Needle, Portex combined spinal epidural kit
- Volunteers
- 80 people
- Sponsor
- Menoufia University
Postoperative Pain
Transversus Abdominis Plane Versus Quadratus Lumborum Block for Pediatrics
The purpose of this research study is to find the best way to decrease pain in children whom have had low abdominal surgery. Investigators will perform two technique of trunk block; Transversus abdominis plane or Quadratus…
- Trial name
- NCT02715999
- Testing
- Quadratus Lumborum Block, Transversus Abdominis Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Liver Transplant; Complications, Inflammatory Response
Effect of Transversus Abdominis Plane Block on Anti-inflammatory Response
The liver transplantation is the only treatment for end-stage liver failure. Lack of sufficient organs from the cadaver to meet the organ needs has increased the interest in a live organ donor transplantation.
- Trial name
- NCT04232904
- Testing
- Transversus abdominous plane block (TAP Block)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Inonu University
Bell's Palsy
Ultrasound-Guided Corticosteroid and Bupivacaine for Facial Nerve Function and Thickness in Bell's Palsy
This prospective, single-arm clinical study aims to evaluate the effects of a one-time, ultrasound-guided injection of corticosteroid (triamcinolone) combined with local anesthetic (bupivacaine) into the facial nerve in patients…
- Trial name
- NCT06955455
- Testing
- Triamcinolone and Bupivacaine Injection
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Tishreen University Hospital
Postoperative Pain
An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Undergoing Hysterectomy
The objective is to identify the optimal dose of SABER-Bupivacaine for postoperative pain control in patients undergoing hysterectomy on the basis of pharmacokinetics, efficacy and safety evaluations.
- Trial name
- NCT00993226
- Testing
- SABER-Bupivacaine Treatment 1a, Bupivacaine HCl Treatment 1c, SABER-Bupivacaine Treatment 2a
- Where
- 14 sites in France, Germany and 4 more
- Volunteers
- 115 people
- Sponsor
- Durect
Pain
Comparison of Low-dose Epidural With Intravenous Narcotic Versus Intravenous Narcotic Alone
The purpose of the study is to determine if a low-dose epidural drug mixture without narcotic will result in lower parenteral narcotic usage, and improved side-effect profile for post-operative pain in the pediatric population…
- Trial name
- NCT00287326
- Testing
- Bupivacaine, Clonidine, Morphine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
CHRONIC POST-TRAUMATIC NEUROPATHIC PAIN IN ANKLE AND FOOT
Pilot RCT of Efficacy of Perineural Local Anesthetics and Steroids for Chronic Post-traumatic Ankle and Foot Pain
Injections of local anesthetics (freezing) and steroids are often performed around injured nerves in individuals with nerve injury-related pain.
- Trial name
- PREPLANS (NCT02680548)
- Testing
- 0.9% saline, 0.25% bupivacaine hydrochloride injectable suspension USP, 4mg/cc methylprednisolone acetate injectable suspension USP
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University Health Network, Toronto
Laparoscopic Cholecystectomy
One-Puncture Versus Multipoint Technique of Rectus Sheath Block With Transverse Abdominis Plane Block
the purpose of this study is to compare of better postoperative analgesia following laparoscopic cholecystectomy using either one puncture rectus sheath block with transverse abdominis plane block or multipoint technique
- Trial name
- NCT06599255
- Testing
- US-guided RSB and TAPB by one-puncture technique., multipont
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Zagazig University
Pain, Postoperative, Spine Disease
Ultrasound Guided Modified Thoracolumbar Interfascial Plane Block for Spinal Surgery
Ultrasound guided thoracolumbar interfascial plane (TLIP) block was first described in 2015 by Hand et al. TLIP block involves injection of local anesthetics between multifidus and longissimus muscles at the third lumbar vertebra…
- Trial name
- TLIP (NCT03079076)
- Testing
- Bupivacaine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ataturk University
Postoperative Pain
Effect of Preemptive Intramuscular Diclofenac on Minimal Effective-Dose Bupivacaine Saddle Block for Minor Perianal Surgeries
The research will be carried out in order to test the effect of Intramuscular (IM) Diclofenac, administered as preemptive analgesic with minimal effective dose spinal anesthesia in perianal surgeries, on prolonging the time to…
- Trial name
- NCT04849468
- Testing
- Declofenac, saline
- Where
- Saudi Arabia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Breast Cancer, Postoperative Pain, Acute
Rhomboid Intercostal Plane Block on Chronic Pain Incidence and Acute Pain Scores After Mastectomy
Rhomboid intercostal block is used to block lateral cutaneous branches of intercostal nerves between T3 and T9 dermatomes. RIB has been reported to be successful in attenuating acute pain following breast surgeries.
- Conditions
- Breast Cancer, Postoperative Pain, Acute, Postoperative Pain, Chronic, Neuropathic Pain
- Trial name
- NCT06019325
- Testing
- RIB
- Where
- Turkey (Türkiye)
- Volunteers
- 254 people
- Sponsor
- Muğla Sıtkı Koçman University
Episiotomy
Effect of Levobupivacaine Infiltration on the Post Partum Perineal Pain in Episiotomy, in Primiparous Women After Instrumental Delivery
An episiotomy is an incision of the perineum to facilitate childbirth by natural means. Perineal pain are more frequent and intense if the incision of the perineum is important.
- Trial name
- NCT02796547
- Testing
- Levobupivacaine, Physiological serum
- Where
- 2 sites in Belgium, France
- Sponsor
- Brugmann University Hospital
Catheter; Pain (Indwelling Catheter)
Effects of PECS 1 Block on Venous Cancer Port Catheter
In this study our aim is to investigate the effects of ultrasound (USG) guided pectoral block (PECS) type 1 in the administration of an implanted port-a-cath .
- Trial name
- NCT04170699
- Testing
- Port-a-cath replacement
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Pre-emptive, Postoperative Pain
Ultrasound-Guided Mid-Point Transverse Process to Pleura Block for Thoracotomy Incisions
This study is designed to investigate the analgesic efficacy of pre-emptive ultrasound-guided midpoint transverse process to pleura (MTP) block for posterolateral thoracotomy in cardiothoracic surgeries.
- Conditions
- Pre-emptive, Postoperative Pain, Thoracotomy
- Trial name
- NCT05044858
- Testing
- Midpoint transverse process block group
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Postoperative Pain
A Safety and Effectiveness Study of SABER®-Bupivacaine for Pain Following Shoulder Surgery
This is a research study testing SABER-Bupivacaine (an experimental pain-relieving medication). SABER-Bupivacaine is designed to continuously deliver bupivacaine, a common local anesthetic, for a few days in order to treat local…
- Trial name
- NCT00818363
- Testing
- SABER-Bupivacaine
- Where
- 9 sites in Australia, New Zealand
- Volunteers
- 60 people
- Sponsor
- Durect
Video Assisted Thoracic Surgery
Pectoral Fascial Plane and Serratus Anterior Plane Blocks With Bupivacaine v. Liposomal Bupivacaine
Patients will be randomized the day of surgery upon presentation to the operating room to either a treatment group (PECSII/SAP blocks with bupivacaine HCl plus liposomal bupivacaine) or a control group (PECSII/SAP blocks with…
- Trial name
- NCT03731221
- Testing
- Bupi HCI and lipo bupi, Bupi HCI
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Pain
Dexmedetomidine Versus Fentanyl as Adjuvants to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane Block
The aim and objective of this study is to compare dexmedetomidine and fentanyl as adjuvants to bupivacaine in ultrasound guided TAP block analgesia in patients undergoing radical cystectomy as regarding postoperative analgesic…
- Trial name
- NCT04318158
- Testing
- Bupivacaine, Dexmedetomidine, Fentanyl
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
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