Clinical trials: Bupivacaine
Femoral Neck Fracture
Fascia Iliaca Block in the Emergency Department for Analgesia After Femoral Neck Fracture
Femoral neck fracture is very common in the elderly and can produce severe to moderate pain. As this pathology is not life-threatening, waiting time in the emergency department may be prolonged due to the high number of…
- Trial name
- NCT02433548
- Testing
- Fascia iliaca block
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Obesity, Morbid, Surgery
Multimodal Analgesia Effect on Post Surgical Patient
Patients undergoing Bariatric Surgery at the University of California Davis Medical Center will be divided into two groups, one receiving Standard of Care pain control medications vs the second group which will receive…
- Conditions
- Obesity, Morbid, Surgery, Bariatric Surgery Candidate
- Trial name
- NCT04240626
- Testing
- Neurontin, Dilaudid Injectable Product, Marcaine Injectable Product
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Davis
Pain Management
Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery
Opioids are prescribed for moderate to severe pain disorders; however, there are contraindications and side effects that are common to all opioids.
- Trial name
- NCT03757715
- Testing
- Bupivacaine, Dexamethasone
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama at Birmingham
Nerve Pain
The Feasibility of Performing Erector Spinae (ESP) Nerve Block in Bariatric Patients; a Case Series Study
This study is a pilot study to assess the effectiveness of erector spinae (ESP) nerve blocks for postoperative pain control following bariatric surgery.
- Trial name
- NCT04477525
- Testing
- Ultrasound Guided Erector Spinae Plane (ESP) Nerve Block, Bupivacaine Injection
- Sponsor
- Montefiore Medical Center
Failed Moderate Sedation During Procedure
The Effects of Single-dose Rectal Midazolam Application on Post-operative Recovery
This study aimed to compare the efficiency of rectal midazolam addition after applying bupivacaine and caudal anesthesia on postoperative analgesia time, the need for additional analgesics, postoperative recovery, sedation, and…
- Trial name
- NCT02127489
- Testing
- 1 mL/kg bupivacaine 0.25%.
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Karadeniz Technical University
Pain, Postoperative, Anesthesia, Local
Postoperative Analgesia in Laparoscopic Abdominal Surgery After Exparel Via TAP or Local Infiltration
This study evaluates differences in how administering liposomal bupivacaine via two different methods affects postoperative pain control in laparoscopic abdominal surgery patients.
- Conditions
- Pain, Postoperative, Anesthesia, Local, Anesthesia; Functional, Anesthesia
- Trial name
- NCT03927326
- Testing
- Exparel 266 MG Per 20 ML Injection
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Washington
Acute Pain
Liposomal Bupivacaine Interscalene Blocks for Rotator Cuff Repair
The purpose of this study is to compare pain control after arthroscopic rotator cuff repair surgery using either liposomal bupivacaine or bupivacaine when injected in an interscalene block.
- Trial name
- RCR (NCT03587584)
- Testing
- liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Minnesota
ACL, Anterior Cruciate Ligament Injuries
Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery
The purpose of this randomized controlled trial is to assess a new analgesia regimen that includes the addition of genicular never blocks to our current standard regimen of peripheral nerve blocks, which includes an adductor…
- Trial name
- NCT05720949
- Testing
- Genicular Nerve Block with bupivacaine and preservative free dexamethasone
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Hospital for Special Surgery, New York
Pain, Postoperative
Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty
Total shoulder arthroplasty (TSA) is considered to be a major surgical procedure resulting in severe postoperative pain, especially in the first 48 hours after surgery.
- Trial name
- NCT02876055
- Testing
- Single shot interscalene nerve block, Continuous interscalene nerve block, Local Infiltration Analgesia (LIA)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Proximal Femur Fractures
Fascia Iliaca Compartment Block for Proximal-end Femur Fractures
Fracture femur is a common injury which is associated with excruciating pain. Positioning for neuraxial blocks is always challenging because even slight overriding of the fracture ends is intensely painful .It can causing major…
- Trial name
- NCT02696915
- Testing
- Bupivacaine, Ultrasound guided fascia iliaca compartment block, Intrathecal medications (bupivacaine (15 mg) in conjunction with fentanyl 20 micrograms)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Pain, Acute Post-Operative, Nausea and Vomiting, Postoperative
Catheter Redosing of Autonomic Neural Blockade After Sleeve Gastrectomy
Postoperative visceral pain and autonomic symptoms after laparoscopic sleeve gastrectomy may reappear earlier in selected high-risk patients despite standard intraoperative autonomic neural blockade (ANB).
- Trial name
- NCT07655908
- Testing
- Bupivacaine 0.5% and Dexamethasone via Temporary Catheter
- Volunteers
- 30 people
- Sponsor
- Universidad Simón Bolívar
Post-surgical Pain
Study of CA-008 (Vocacapsaicin) in Bunionectomy Patients
This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled, parallel design study evaluating a single dose of one of three CA-008 dose levels vs.
- Trial name
- NCT03599089
- Testing
- CA-008, Ketorolac, Acetaminophen
- Where
- 3 sites in United States
- Volunteers
- 147 people
- Sponsor
- Concentric Analgesics
Pain, Postoperative
Post Operative Pain Management for ACL Reconstruction
Health care providers are seeking methods to limit post-operative pain and opioid prescriptions to reduce the burden of the national opioid use epidemic.
- Trial name
- NCT05316168
- Testing
- Bupivacaine HCl 0.5% Injectable Solution, Dexamethasone, Infiltration between Popliteal Artery and Capsule of the knee (iPACK)
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Acute Postoperative Pain, Thoracotomy Surgery
Intertransverse Process Block for Postoperative Analgesia After Thoracotomy and Lobectomy
This prospective, randomized, triple-blind, placebo-controlled clinical trial will investigate the effectiveness of the intertransverse process block (ITPB) for postoperative analgesia in patients undergoing elective thoracotomy…
- Conditions
- Acute Postoperative Pain, Thoracotomy Surgery, Intertransverse Process Block
- Trial name
- NCT07335250
- Testing
- Intertransverse Process Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Konya City Hospital
Erector Spinae Plane Block
Continuous ESP Block in Patients Undergoing CABG Surgery.
This study addresses articles and studies related to the erector spinae plane (ESP) block and its technique, advantages and disadvantages, applicability, among others.
- Trial name
- NCT07666178
- Testing
- Ropivacaine, Standard Postoperative Analgesics
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- Instituto do Coracao
Postoperative Pain, Cardiac Surgery
Dexmedetomidine Combined With Bupivacaine in Ultrasound-guided Pecto-Intercostal Fascial Block in Cardiac Surgery
Recent advancements in pain management techniques suggest that ultrasound-guided peripheral nerve blocks may significantly benefit patients undergoing cardiac surgery.
- Trial name
- NCT07023874
- Testing
- Bupivacaine group, bupivacaine + dexmedetomidine group
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Postoperative Pain
Infra-orbital Nerve Block for Post Operative Analgesia in Children Undergoing Cleft Lip Surgery.
this study will be undertaken to evaluate the safety and analgesic efficacy of adding ketamine to bupivacaine in bilateral infra-orbital nerve block for relief of pain postoperatively following repair of cleft lip in children…
- Trial name
- IFONB (NCT02514980)
- Testing
- Bupivacaine, Ketamine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Postoperative Pain
Ultrasound Guided Intermediate Cervical Plexus Block in Thyroid Surgery
studying the effect of dexmeditomidine addition to bupivacaine in bilateral intermediate cervical block for patients undergoing thyroidectomy under general anaesthesia
- Trial name
- NCT03731468
- Testing
- local anesthetic, Dexamethasone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Patient Satisfaction
Predicting Ultrasound-Guided Thoracic PVB Success in Herpetic Neuralgia
This study aims to fill the knowledge gap by investigating the predictors of success for TPVB in patients with herpetic neuralgia.
- Trial name
- NCT06761924
- Testing
- Ultrasound-Guided Thoracic Paravertebral nerve block
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Beni-Suef University
ACL, Postoperative Pain
Exparel vs Block for ACL Reconstruction
Liposomal bupivacaine or Exparel (Pacira Biosciences) is a long-lasting nonopioid analgesic that was initially utilized as an infiltrative agent but has more recently become U.S.
- Trial name
- NCT06006624
- Testing
- Exparel 30 mL, 0.5% bupivacaine, Dexamethasone
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics