Clinical trials: Bupivacaine
Osteoarthritis, Knee, Osteoarthritis, Hip
Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)
The purpose of this study is to determine whether liposomal bupivacaine is effective in the management of pain following total joint arthroplasty, as compared to standard of care analgesia.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Shoulder
- Trial name
- NCT02197273
- Testing
- Liposomal bupivacaine, Standard of care analgesia
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- OhioHealth
Post Spinal Anaesthesia Hypotension
Comparison Between Intravenous Hydrocortisone and Ondansetron in Prevention of Post Spinal Anesthesia Hypotension
The purpose of this study is to assess and contrast the effectiveness of intravenous ondansetron and intravenous hydrocortisone in avoiding spinal anesthesia-induced hypotension.
- Trial name
- NCT06930456
- Testing
- hydrocortisone, ondansetron
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Nada kamel Elgamal
Urethral Stricture
Liposomal Bupivacaine To Control Post-Operative Pain Following BMG
This is a single blinded-randomized controlled trial that recruit male patients for substitution urethroplasty using buccal mucosal graft.
- Trial name
- NCT03720223
- Testing
- Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Urology of Virginia
Breast Surgery
Adenosine and Magnesium Sulphate as Adjuvants for PECS Block.
Pectoral nerve block (PECS) has been used for post-operative pain relief in patients undergoing breast surgery. It has been shown that adenosine has an effect on pain modulation.
- Trial name
- NCT03344679
- Testing
- Bupivacaine 0.25%, Adenosine 12mg, Magnesium Sulphate 500 mg
- Volunteers
- 90 people
- Sponsor
- Menoufia University
Catheter Related Bladder Discomfort
Paracetamol for Catheter Related Bladder Discomfort
The insertion of an urinary catheter in a patient undergoing a surgical procedure, especially in urinary interventions, may lead to catheter-related bladder discomfort with varying degrees of severity during the postoperative…
- Trial name
- NCT01652183
- Testing
- intravenous paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Pinar Ergenoglu
Analgesia
Regional Blocks for Lumbar Disc Surgery Analgesia
Objective The goal of this prospective randomized controlled experiment was comparing the analgesic efficacy, opioid needs, and adverse effect profiles of Paravertebral Block (PVB), Thoracolumbar Interfascial Plane Block (TLIP)…
- Trial name
- NCT06933641
- Testing
- Regional Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Postoperative Complications
Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?
the investigators aim is to investigate and explore the effect 10 mg morphine added to local anesthetics in serratus anterior plane block for post mastectomy pain management after modified radical mastectomy in patients with…
- Trial name
- NCT02962024
- Testing
- Morphine Sulfate, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fatma Adel El sherif,MD
Chronic Disease, Nasal Polyposis
Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Chronic Rhinosinusitis With Nasal Polyposis
Chronic rhinosinusitis (CRS) with nasal polyps is a particularly challenging form of chronic rhinosinusitis in several ways. Patients have significantly more severe symptom burden and worse quality of life than patients with…
- Conditions
- Chronic Disease, Nasal Polyposis, Rhinitis
- Trial name
- NCT02784262
- Testing
- botox injection Multiguide
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- Norwegian University of Science and Technology
Prophylactic, Mirtazapine
Prophylactic Mirtazapine and Different Doses of Intrathecal Morphine in Preventing Nausea and Vomiting After Cesarean Section
The aim of this work was to evaluate the role of prophylactic mirtazapine and different doses of intrathecal morphine in preventing nausea and vomiting.
- Conditions
- Prophylactic, Mirtazapine, Intrathecal, Morphine
- Trial name
- NCT06681805
- Testing
- Mirtazapine + Bupivacaine + Morphine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Kafrelsheikh University
Pain, Postoperative
Comparison Of Erector Spinae Plane Block With Transversus Abdominis Plane Block For Postoperative Pain Management In Patients Undergoing Total Abdominal Hysterectomy
Hysterectomy is the second most common major Obstetric/gynecology procedure worldwide and one of the most common procedures in our institute. Post-operative pain is one of the most common complications following hysterectomy.
- Trial name
- NCT05521841
- Testing
- Erector Spinae Plane Block(Bilateral Ultrasound Guided Erector Spinae Plane Block), Transversus abdominis plane block(Bilateral Ultrasound-guided bilateral Transversus abdominis plane block)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Arthroplasty, Knee Replacement
Neurostimulation an Adjuvant Postoperative Analgesic in Total Knee Replacement (TKR) Surgeries
To study and evaluate the effect of using the Primary Relief PENS treatment as adjuvant analgesia for reducing pain in total knee replacement (TKR) patients.
- Trial name
- TKR (NCT05416294)
- Testing
- Primary Relief, Inactive Primary Relief
- Sponsor
- DyAnsys, Inc.
Intracapsular Fracture of Femur, Femoral Neck Fractures
Hip Fracture Exparel Administration Trial Capsule During Hemiarthroplasty
This study will examine the efficacy of Liposomal Bupivacaine (Exparel) in hip fracture patients undergoing hip hemiarthroplasty for femoral neck fractures through a posterior approach.
- Conditions
- Intracapsular Fracture of Femur, Femoral Neck Fractures, Hip Hemiarthroplasty
- Trial name
- HEAT (NCT03502018)
- Testing
- Bupivacaine liposome, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Maimonides Medical Center
NMIBC, TURBT
Anesthesia Modality and Oncologic Outcomes in High-Risk NMIBC: A Randomized Trial
To demonstrate the superior efficacy of spinal anesthesia (SA) versus general anesthesia (GA) according to the delay of time to recurrence in high-risk NMIBC patients up to Week 104 after TURBT.
- Conditions
- NMIBC, TURBT, Bladder (Urothelial, Transitional Cell) Cancer, Bladder Cancer Recurrence
- Trial name
- NCT06982690
- Testing
- Spinal Anesthesia, General Anesthesia
- Where
- Taiwan
- Volunteers
- 370 people
- Sponsor
- National Taiwan University Hospital
Pain Management in Breast Surgery, Pain After Surgery
Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Breast-Conserving Surgery Versus Serratus Anterior Block Combined With Additional Pecto-Intercostal II Block
This prospective randomized study will compare the effects of Erector Spinae Plane Block (ESPB) and Serratus Anterior Plane Block combined with Pectoral Nerve Block Type II (SAPB + PECS II) on intraoperative analgesia and…
- Conditions
- Pain Management in Breast Surgery, Pain After Surgery, Regional Anaesthesia
- Trial name
- NCT07368413
- Testing
- SAPB + PECS II Technique, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kayseri City Hospital
Postoperative Pain, Opioid Use
Erector Spinea Plane Block in Pediatric Hip Surgery
This prospective randomized controlled double-blind study will be carried out to evaluate the effect of ultrasound-guided erector spinae plane block on the postoperative analgesia in children after hip surgeries, the total…
- Trial name
- NCT04374396
- Testing
- Real ultrasound-guided single shot erector spinae plane block (ESP B)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Inguinal Hernia
Effects of Morphine Added to Bupivacaine in Transversus Abdominis Plane Block for Inguinal Hernia Repair
This study is conducted to determine whether morphine added to bupivacaine in ultrasound guided (USG) transversus abdominis plane (TAP) block has beneficial effects than bupivacaine alone in providing postoperative analgesia for…
- Trial name
- NCT05379374
- Testing
- bupivacaine and morphine
- Where
- Nepal
- Volunteers
- 40 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Mastectomy, Peripheral Nerve Block
Comparison of the Postoperative Analgesic Effects of SPSIPB and TPB in Mastectomy Operations
Breast cancer is the most common malignancy in women, and surgery is one of the cornerstone treatments for breast cancer. Postoperative pain can significantly reduce patients' quality of life and acute pain may even trigger…
- Conditions
- Mastectomy, Peripheral Nerve Block, Pain Management
- Trial name
- NCT06789146
- Testing
- Serratus posterior superior intercostal plane block, Thoracic Paravertebral Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Lumbar Fixation Surgery
Evaluation Of Three Different Anagesic Techniques In Patients Undergoing Lumbar Fixation Surgery
Lumbar spinal stenosis is a degenerative condition characterized by the narrowing of the space surrounding the neurovascular structures of the lumbar vertebrae, resulting from age-related changes in the intervertebral discs…
- Trial name
- NCT06801574
- Testing
- Erector Spinae Plane Block, infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ataturk University
Thoracic Surgery, Video-Assisted
Erector Spinae Plane (ESP) Block vs Intravenous Lignocaine Infusion in (VATS)
The goal of this clinical trial is to compare analgesic efficacy of erector spinae plane (ESP) block vs intravenous lignocaine infusion in video- assisted thoracoscopy (VATS.
- Trial name
- NCT06289790
- Testing
- Erector Spinae Plane (ESP) block, Lignocaine, Bupivacaine
- Where
- Poland
- Volunteers
- 61 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Pediatric Thoracoscopy
Retrolaminar Block for Pediatric Thoracoscopic Sympathectomy
Thoracoscopic sympathectomy is a rapid and simple technique associated with rare complications, but it is associated with severe postoperative pain that makes breathing and coughing difficult resulting in increased occurrence of…
- Trial name
- NCT04688918
- Testing
- Retrolaminar block, paravertebral group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
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