Clinical trials: Bupivacaine
Pancreatitis, Chronic
Prospective Study on Endoscopic Ultrasound (EUS) Celiac Bloc Efficacy in Chronic Pancreatitis
The purpose of this study is to determine if celiac bloc (with injection of steroid and local anesthetic) is superior to a sham procedure for pain control and quality of life improvement in patient with chronic pancreatitis and…
- Trial name
- NCT01318590
- Testing
- EUS procedure with drug injection, EUS procedure
- Where
- 2 sites in Belgium, Canada
- Volunteers
- 2 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pregnancy, Cesarean Section
Different Approaches to Maternal Hypotension During Cesarean Section
The aim of this study is to compare two different therapeutic approaches to blood pressure reduction: pharmacological vs. non-pharmacological.
- Conditions
- Pregnancy, Cesarean Section, Anesthesia,Spinal, Hypotension
- Trial name
- NCT00991627
- Testing
- Bupivacaine, Morphine, Lactated Ringer's solution
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Parma
Post Operative Analgesia, Total Knee Arthroplasty
Supplementary Nerve Blocks Added to the Adductor Canal Block for Postoperative Pain Management in Primary Total Knee Arthroplasty: A Randomized Controlled Comparison of Sciatic, BiFeS, and IPACK Techniques
Postoperative pain following total knee arthroplasty (TKA) is a significant clinical problem that delays early mobilization, reduces patient satisfaction, and increases analgesic requirements.
- Trial name
- NCT07242170
- Testing
- Adductor canal block, BiFeS Block (Biceps Femoris Short Head Block), IPACK block
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Erzincan University
Knee, Arthroscopy
Analgesic Control Following Knee Arthroscopy
This study aims to investigate the analgesic effects offered by bupivacaine and Durolane (a hyaluronic acid supplement) administered immediately following the completion of knee arthroscopy.
- Conditions
- Knee, Arthroscopy, Analgesia
- Trial name
- NCT01169389
- Testing
- Intraarticular injection, Intra-articular injection of 0.5% Bupivacaine
- Where
- Ireland
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Research and Innovation Foundation, Ireland
Cleft Palate Children, Block
Suprazygomatic Nerve Block vs Surgical Site Infiltration in Cleft Palate Repair
The aim of this study is to evaluate the efficacy and duration of effect of bupivacaine given preoperatively as a bilateral suprazygomatic maxillary nerve block and to compare it with peri-incisional infiltration with the same…
- Trial name
- NCT03799068
- Testing
- suprazygomatic maxillary nerve block, surgical site infiltration
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gall Stones
Intraperitoneal Techniques of Local Anaesthesia During Laparoscopic Cholecystectomy
Pain following laparoscopic cholecystectomy (LC) results in morbidity and is a barrier to same day discharge. In several trials local anaesthetic (LA) washed over the liver and gall bladder decreases pain.
- Trial name
- NCT01090882
- Testing
- Bupivocaine, 0.9% normal saline solution
- Where
- United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Patient Satisfaction
Predicting Ultrasound-Guided Thoracic PVB Success in Herpetic Neuralgia
This study aims to fill the knowledge gap by investigating the predictors of success for TPVB in patients with herpetic neuralgia.
- Trial name
- NCT06761924
- Testing
- Ultrasound-Guided Thoracic Paravertebral nerve block
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Beni-Suef University
Labor Pain
The WE Pilot Study: Walking Epidurals
The primary objective of the study is to assess the feasibility of a walking epidural protocol in our center. This study will provide a small data set for a larger prospective randomized controlled study.
- Trial name
- NCT03710382
- Testing
- Walking epidural
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pain
Pharmacokinetic Evaluation of EXPAREL in Adults Undergoing Tonsillectomy
The purpose of this study is to characterize the pharmacokinetic (PK) profile of a single dose of EXPAREL (133 mg/10 mL) administered intraoperatively per normal infiltration for prolonged analgesia in 12 adult subjects…
- Trial name
- NCT02199574
- Testing
- EXPAREL
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Elective Caesarean Section Surgeries
Intrathecal Levobupivacaine With Opioids for Caesarean Section
In this prospective, randomized, double-blind, controlled study, the aim was to compare the effect of adding fentanyl (10 µg) or sufentanil (2.5 µg) to levobupivacaine (2.2±0.2 ml 0.5%) on the intraoperative anesthesia quality…
- Trial name
- NCT01858090
- Testing
- Control Group Chirocaine, Group Fentanyl, Group sufentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Baskent University
Acute Pain
The Effect of Erector Spinae Plane Block Performed Under Direct Vision on Postoperative Pain in Spine Surgery
Spine surgery is typically associated with severe postoperative pain. Although the number of spine surgeries has increased day by day, postoperative pain management have been limited.
- Trial name
- ESPOUSES (NCT03960528)
- Testing
- Erector spinae plane block, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bezmialem Vakif University
Postoperative Pain
Lumbar Erector Spinae Plane Block and Quadratus Lumborum Block in Hip and Proximal Femur Surgeries
Multimodal analgesia is used to control postoperative pain in hip surgery. Quadratus lumborum block is an effective regional anesthesia technique for hip and proximal femur surgery.
- Trial name
- NCT03508544
- Testing
- Lumbar ESP block, QLB bLock, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Maltepe University
Hysterectomy (MeSH nr: E04.950.300.399)
Effects of General Anesthesia and Spinal-Morphine Anesthesia on Recovery and Comfort After Benign Abdominal Hysterectomy
The purpose of this study is to determine whether spinal anesthesia combined with intrathecal morphine in abdominal hysterectomy on benign gynecological indications gives better outcome concerning duration of hospital stay and…
- Trial name
- NCT00527332
- Testing
- Bupivacain, Morphine, Propofol
- Where
- 5 sites in Sweden
- Volunteers
- 180 people
- Sponsor
- Preben Kjolhede
Postoperative Pain
Total Knee Arthroplasty Infiltration Study for Postoperative Analgesia
This is a Phase 2b, randomized, double-blind, saline placebo- and active-controlled, multicenter study in subjects undergoing primary unilateral total knee arthroplasty (TKA) to evaluate the analgesic efficacy, safety, and…
- Trial name
- NCT03015532
- Testing
- HTX-011, Bupivicaine HCl, Ropivacaine
- Where
- 24 sites in United States
- Volunteers
- 285 people
- Sponsor
- Heron Therapeutics
Lower Limb Surgery
Minimum Effective Dose of 0.5% Bupivacaine for Ultrasound-guided Spinal Anesthesia Using Taylor's Approach
This study aims to determine the minimum effective dose of bupivacaine 0.5% in 90% of patients undergoing lower limb surgery with ultrasound-guided spinal anesthesia using Taylor's approach.
- Trial name
- MEDBST (NCT03899038)
- Testing
- spinal anesthesia
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Huazhong University of Science and Technology
Pain After Carpal Tunnel Release
Comparison of Bupivacaine and Exparel for Carpal Tunnel Release
Carpal tunnel syndrome is one of the most common surgeries performed per year in the United States, accounting for over 600,000 surgeries. The procedure is commonly performed under light sedation and local anesthesia.
- Trial name
- NCT02141178
- Testing
- Bupivacaine, Exparel
- Where
- United States
- Sponsor
- University of Pittsburgh
Shoulder Adhesive Capsulitis
Best Treatment Modality of Frozen Shoulder
This study will compare between the effect of three treatment modalities of shoulder adhesive capsulitis to hilight the best technique to improve pain and range of motion outcome measures .
- Trial name
- NCT04897308
- Testing
- Local injection of shoulder joint
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Sohag University
Upper Extremity Injury
Single Versus Double Injection Costoclavicular Block
In this trial, the objective is to compare single- and double-injection ultrasound-guided costoclavicular blocks. The rationale behind this idea is that a second local anesthetic injection, inside the costoclavicular space, may…
- Trial name
- NCT03595514
- Testing
- Single injection, Double injection, lidocaine, bupivacaine, epinephrine, dexamethasone
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Erector Spinae Plane Block, Paravertebral Block
ESPB vs PVB vs QLB After Pelvi-ureteric Surgeries
The aim of this study is to compare the analgesic efficacy of erector spinae plane block versus thoracic paravertebral block versus quadratus lumborum block on postoperative analgesia after pelvi-ureteric surgeries.
- Conditions
- Erector Spinae Plane Block, Paravertebral Block, Quadratus Lumborum Block, Analgesia
- Trial name
- NCT05713643
- Testing
- ESPB Technique, TPVB Technique, QLB Technique
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Kafrelsheikh University
Postoperative Pain
Dexamethasone Versus Demedetomidine Addition for Adductor Canal Block
Single-injection peripheral nerve block (PNB) is commonly used for perioperative analgesia and anesthesia. Three approaches for extending the duration of PNB include continuous PNB with catheter-based techniques, novel local…
- Trial name
- NCT06527976
- Testing
- Dexmedetomidine, Dexamethasone
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
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