Clinical trials: Bupivacaine
Foot Surgery, Ankle Surgery
Liposomal Bupivacaine With Dexamethasone for Foot Surgery
This study aims to understand the ideal formulation to utilize in saphenous nerve and popliteal nerve blocks for foot and ankle procedures.
- Conditions
- Foot Surgery, Ankle Surgery, Post Operative Pain, Popliteal Nerve Block
- Trial name
- NCT06465992
- Testing
- Exparel 266 MG Per 20 ML Injection, Bupivacaine Hcl 0.75% Inj, Dexamethasone
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Total Knee Arthroplasty, Postoperative Pain
Regional Anesthesia in TKA: Impact on Postoperative Joint Motion and Patient Satisfaction
This is a single-center, prospective, randomized controlled trial aiming to evaluate the effects of different regional anesthesia/analgesia techniques on postoperative knee range of motion (ROM) and patient satisfaction following…
- Conditions
- Total Knee Arthroplasty, Postoperative Pain, Regional Anesthesia, Knee Range of Motion
- Trial name
- NCT07124494
- Testing
- Regional anethesia
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Konya City Hospital
Total Knee Arthroplasty
Periarticular Bupivacaine + Meloxicam ER Solution Versus Standard Practice During Total Knee Arthroplasty
The purpose of this study is to compare an FDA-approved medication for post-operative pain control (HTX-011) to the standard of care institutional practice for periarticular analgesia after primary total knee arthroplasty (weight…
- Trial name
- NCT05188053
- Testing
- HTX-011, ropivacaine , epinephrine , ketorolac diluted in sodium chloride
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Mayo Clinic
Hemodynamic Instability
Comparison of Effects of Scalp Block and Intravenous Esmolol on Hemodynamic Response Following the Skull Pins Application for Elective Supratentorial Craniotomy
The goal of this clinical trial is to compare hemodynamic response (MAP, SBP, DBP and HR) between scalp block and intravenous esmolol while skull pins application in patients undergoing elective supratentorial craniotomy under…
- Trial name
- NCT06268275
- Testing
- Scalp block, Esmolol
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Haemodynamic Instability
To Determine the Effectiveness of Saddle Block vs Spinal Anesthesia in TURP
To determine the effectiveness of saddle block vs spinal anesthesia in TURP.
- Trial name
- NCT05285800
- Testing
- 0.5% Hyperbaric Bupivacaine
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hamdard University
Postoperative Pain Management, Postoperative Pain
Postoperative Analgesic Efficacy of Modified TAPA and QL Blocks in Laparoscopic Cholecystectomies
Comparison of Postoperative Analgesic Effects of M-TAPA and Anterior Quadratus Lumborum Blocks in Laparoscopic Cholecystectomies.
- Conditions
- Postoperative Pain Management, Postoperative Pain, Analgesia, Nerve Blocks
- Trial name
- NCT06540586
- Testing
- anterior Quadratus lumborum block, M-TAPA BLOCK
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Coarctation of Aorta
The Effect of Paravertebral Block With Dexamethasone on Intraoperative and Postoperative Analgesia in Children Undergoing Surgery for Coarctation of Aorta
Anesthetic management for surgery of aortic coarctation needs special care due to severe pain during lateral thoracotomy incision, the intraoperative hemodynamic instability related to skin incision at lateral thoracotomy…
- Trial name
- NCT03074773
- Testing
- Dexamethasone, ultrasound, paravertebral block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Colon Cancer, Colon Diverticulosis
Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery
The General Objective of this study is to investigate the cost and efficacy of treating patients undergoing colorectal surgical resections with an opioid limited pain control regimen as part of an Enhanced Recovery After Surgery…
- Conditions
- Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis
- Trial name
- NCT02958566
- Testing
- Acetaminophen, Gabapentin, Orphenadrine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Illinois College of Medicine at Peoria
Nerve Block
Serratus Anterior Plane Block for Pain Treatment After Video-Assisted Thoracoscopic Surgery
Analgesia following video-assisted thoracoscopic surgery (VATS) is important for the prevention of postoperative pulmonary complications.Various regional methods of anesthesia are currently being used to achieve this goal.
- Trial name
- NCT03217292
- Testing
- Serratus Anterior Plane Block, IV patient-controlled analgesia (PCA) tramadol
- Volunteers
- 40 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Analgesic Efficacy, External Oblique Intercostal Block
Analgesic Efficacy of External Oblique Intercostal Block vs Subcostal Transversus Abdominis Plane Block in Open Surgical Nephrectomy
To compare the efficacy of unilateral ultrasound-guided oblique subcostal transversus abdominis plane block with unilateral ultrasound-guided external oblique intercostal plane block in providing intraoperative and postoperative…
- Conditions
- Analgesic Efficacy, External Oblique Intercostal Block, Subcostal Transversus Abdominis Plane Block, Open
- Trial name
- NCT06584695
- Testing
- Transversus abdominis plane block, External Oblique Intercostal Plane Block, Control group
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Cairo University
Postoperative Analgesia, Retrolaminar Block
Ultrasound-guided Erector Spinae Plane Block Versus Retrolaminar Block for Postoperative Analgesia in Thoracotomy
Comparing efficacy of Ultrasound-guided Erector Spinae Plane Block versus Retrolaminar Block for Postoperative Analgesia in Patients Undergoing Thoracotomy
- Conditions
- Postoperative Analgesia, Retrolaminar Block, Ultrasound-guided Erector Spinae Plane Block, Thoracotomy
- Trial name
- NCT05507281
- Testing
- Ultrasound-guided Erector Spinae Plane Block, Retrolaminar Block, Control
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Nasal Surgery
The Effect of Dexamethasone Added to Bupivacain in Nasal Surgery
Nasal packing is frequently applied after nasal surgery. Nasal packing reduces epistaxis, prevents septal hematoma and stabilizes nasal septum.
- Trial name
- NCT03036605
- Testing
- Bupivacaine, Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Hypospadias, Caudal Block
Multifidus Plane Block Versus Caudal Block for Hypospadias
This study aims to evaluate the safety and efficacy of ultrasound-guided sacral multifidus plane block and compare its analgesic effect to ultrasound-guided caudal block in pediatric patients undergoing hypospadias surgery under…
- Trial name
- NCT06561269
- Testing
- Multifidus plane block, caudal block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Postoperative Pain
Erector Spinae Block Versus Local Field Block in Lumbar Spine Surgeries
Major lumbar spine surgeries are associated with significant postoperative pain that may last for days,So In this study, we intend to evaluate if preventive analgesia with a single injection dose of ultrasound guided bilateral…
- Trial name
- NCT05570565
- Testing
- Erector spinae plane block, local field block
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Total Knee Arthroplasty
Periarticular Injection Versus Fascia Iliaca Block for Total Knee Arthroplasty
In this study, the aim is to compare the efficacy of Periarticular multimodal drug injection(group PI) and Fascia Iliaca Compartment Block ( group FI)for total knee arthroplasty.
- Trial name
- NCT02047331
- Testing
- periarticular injection, fascia iliaca block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Baskent University
Post-thoracotomy Pain
Continue ESPB & Continue ESPB Combined With SAPB for Thoracotomy
Patients who have undergone thoracotomy experience severe pain in the postoperative period. This pain leads to many complications.
- Trial name
- NCT06685445
- Testing
- Active Comparator: Continue Erector Spinae Plane Block, Active Comparator: Continue Erector Spinae Plane Block + Serratus Anterior Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Anesthesia
The Effect of Combined Bilateral Infraorbital and Infratrochlear Nerve Block in Nasal Surgeries
The aim of the study is to assess the efficacy of adding a pre-emptive combined bilateral infraorbital and infratrochlear nerve blocks with bupivacaine 0.25% in decreasing intraoperative and postoperative analgesics consumption…
- Trial name
- NCT06174675
- Testing
- combined bilateral infraorbital and infratrochlear nerve blocks
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Postoperative Pain
Comparison of the Effects of Retro Laminar Block (RLB) and Erector Spina Area Block (ESP) on Postoperative Recovery Quality and Pain in Lumbar Spinal Surgery
The aim of this study is to compare the efficacy of erector spinae plane block (ESPB) and Retrolaminar Block on postoperative recovary quality and pain after lumbar spinal surgery
- Trial name
- NCT05792124
- Testing
- Erector spina area block, Retrolaminar block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Aydin Adnan Menderes University
Percutaneous Pedicular Screw (PPS) Fixation, Minimally Invasive Transforaminal Lumbar Interbody Fusion (MIS TLIF) Surgeries
Comparison of Thoracolumbar Interfascial Plane Block (TLIP-block) and Local Anesthetic (LA) Infiltration in Minimally Invasive Spine Surgery: A Randomized Controlled Trial
The goal of this clinical trial is to compare the effectiveness of the thoracolumbar interfascial plane block (TLIP block) versus local anesthetic (LA) infiltration in managing postoperative pain in minimally invasive surgery…
- Trial name
- NCT06761079
- Testing
- Thoracolumbar interfascial plane block, Local anesthetic infiltration
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Pre-Eclampsia, Cesarean Section
Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery
This study will compare between combination of colloids/crystalloids and crystalloids in women with preeclampsia undergoing elective cesarean delivery under spinal anesthesia
- Trial name
- NCT03252496
- Testing
- Spinal Anesthesia, Intrathecal Bupivacaine, Intrathecal Fentanyl
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Mansoura University
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