Clinical trials: Bupivacaine
Spinal Fractures, Anesthesia, Regional
Effectiveness of Erector Spinae Block in Kyphoplasty
As of October 2019, when the investigators received the approval of the ethics committee, patients who were decided to undergo kyphoplasty with vertebral compression fracture will be included in the study.
- Conditions
- Spinal Fractures, Anesthesia, Regional, Anesthetics, Local, Analgesia
- Trial name
- NCT04201678
- Testing
- CLIA Group (conventional local anesthesia infiltration), EPIAA Group (Extrapedicular infiltration anesthesia), ESP Group (Erector Spina Block)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Gulhane School of Medicine
Anesthesia, Local
Comparing the Hemodynamic Effects of Epinephrine Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Caudal Anaesthesia Assessed by Cardiometry
Electrical cardiometry (EC) is a non-invasive method of estimating cardiac parameters by measuring changes in thoracic bioimpedance during the cardiac cycle.
- Trial name
- NCT05860010
- Testing
- Epinephrine injection, Dexmedetomidine, Bupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 39 people
- Sponsor
- Kasr El Aini Hospital
Postoperative Pain
Comparison Between 3 Solutions of Bupivacaine of Adductor Canal Block for Anterior Cruciate Ligament Reconstruction
Adductor canal block (ACB) is a new technique gaining acceptance as an alternative analgesic method of femoral nerve block (FNB) following knee surgery. The advantage of ACB is its dominant sensory nerve block effect.
- Trial name
- NCT02805920
- Testing
- Bupivacaine
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Procare Riaya Hospital
Parotid Neoplasm, Bupivacaine
Clinical Tolerance of an Intraparotid Injection of Bupivacaine, Combined With Dexamethasone, After Parotidectomy for Benign Tumor
There has been a paradigm shift toward less invasive surgical techniques for parotidectomies, primarily to mitigate post-surgical complications.
- Conditions
- Parotid Neoplasm, Bupivacaine, Dexamethasone
- Trial name
- PAROCAINE (NCT07812259)
- Testing
- Intraparotid injection of bupivacaine/ dexamethasone
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Peripheral Nerve Stimulation, Genicular Nerves
Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study
To compare the effects of the following types of therapy on knee range of motion when given to patients with chronic knee pain: A standard steroid injection Peripheral nerve stimulation (PNS) therapy in combination with a…
- Conditions
- Peripheral Nerve Stimulation, Genicular Nerves, Chronic Knee Pain
- Trial name
- NCT06004882
- Testing
- PNS therapy, Triamcinolone, Bupivacaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- M.D. Anderson Cancer Center
Liposomal Bupivacaine, Preperitoneal Infiltration
Liposomal Bupivacaine Versus Ropivacaine for Preperitoneal Infiltration Analgesia in Upper Abdominal Laparotomy
Upper abdominal open surgery is associated with significant trauma, and postoperative pain management poses considerable challenges.
- Conditions
- Liposomal Bupivacaine, Preperitoneal Infiltration, Analgesia
- Trial name
- NCT07271979
- Testing
- Liposomal bupivacaine, ropivacaine
- Where
- China
- Volunteers
- 146 people
- Sponsor
- Qilu Hospital of Shandong University
Lumbar Spinal Stenosis
Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine
Evaluate the benefit of using liposomal bupivicaine in lumbar laminectomies in terms of length of stay, IV narcotic use, 30-day narcotic use, visual analog score (VAS) and 30-day readmissions
- Trial name
- NCT04066296
- Testing
- Liposomal bupivacaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Femoral Fractures
Effects of Liposomal Bupivacaine for Acute Pain in Hip and Femur Fractures
This is an investigator-initiated, single-center, randomized, patient blinded, controlled trial. The purpose of this study is to compare the effect of a fascia iliaca compartment block (FICB) using 0.2% ropivacaine vs.
- Trial name
- NCT02679560
- Testing
- Liposomal Bupivacaine, Ropivacaine HCL
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Ian Elliott Brown
Recruitment
Low Dose Bupivacaine Versus Prilocaine Regarding Hemodynamic Stability and Safety in Geriatrics
Orthopedic interventions under spinal anesthesia is considered a common practice in elderly patients undergo surgery, and may be associated with lower risks of death, delirium,and major medical complications .
- Trial name
- NCT06382220
- Testing
- Bupivacain
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Fayoum University Hospital
Cardiovascular Surgical Procedures, Pain, Postoperative
Fascial Plane Blocks and Quality of Recovery in Cardiac Surgery
In this randomized trial, the investigators will test the hypothesis that combining regional analgesia techniques-which have the potential to improve the quality of postoperative recovery following median sternotomy-with PIFB…
- Conditions
- Cardiovascular Surgical Procedures, Pain, Postoperative, Cardiovascular Diseases
- Trial name
- NCT07557108
- Testing
- Ultrasound-Guided Pectointercostal Fascial Plane Block, Ultrasound-Guided Rectus Sheath Block, Ultrasound-Guided Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Ordu University
Abdominal Wall Defect
Study to Evaluate Reduction in Pain After Laparoscopic Hernia Repair With Mesh Soaked in Bupivacaine Solution
Early post-operative pain and discomfort after laparoscopic repair remains a concern for patients requiring hospital stay and parenteral narcotic analgesics .
- Trial name
- HAPPIEST (NCT03035617)
- Testing
- Bupivacaine, Saline
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Aga Khan University
Rib Fractures
Ultrasound Guided Emergency Physician Performed Erector Spinae Nerve Block for Rib Fracture Analgesia
The study will be a prospective randomized double blinded placebo controlled clinical trial using ultrasound guided erector spinae plane block as an analgesic adjunct among adult emergency department (ED) patients with rib…
- Trial name
- NCT04168710
- Testing
- ESP block with bupivacaine
- Sponsor
- Yale University
Postoperative Pain, Acute
Dexamedatomidine vs. Dexamethasone in Rhomboidal Intercostal Plain Block and Subserratus Block in Breast Surgery
The aim of this study is to evaluate the analgesic efficacy and safety of adding dexmedetomidine and dexamethasone to bupivacaine in rhomboidal intercostal and subserratus (RISS) block for patients undergoing modified radical…
- Trial name
- NCT05385523
- Testing
- Rhomboid Intercostal and Sub-Serratus block technique (RISS), General Anaesthesia, dexamedatomidine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Armed Forces College of Medicine, Cairo, Egypt
Postoperative Pain
Fentanyl Versus Midazolam As Additives To Bupivacaine In Ultrasound Guided Transversus Abdominis Plane Block
Pain triggers a complex biochemical and physiological stress response leading to impairment of pulmonary, immunological and metabolic functions.
- Trial name
- NCT04426617
- Testing
- Ultrasound Guided Transversus Abdominis Plane Block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Bassant M. Abdelhamid
Bimalleolar Fractures of the Ankle., Sciatic Nerve Block.
To Compare lidocaine2%/Clonidine in Combination, With Bupivacaine 0.5 % Alone in Equal Volumes for Combined Sciatic-saphenous Nerve Block in Terms of Selectivity of Blockade
Clonidine as an adjuvant to local anaesthetics prolongs the postoperative analgesia. It is predominantly an alpha 2 agonist, but does have some alpha 1 activity. Clonidine alone produces analgesia.
- Conditions
- Bimalleolar Fractures of the Ankle., Sciatic Nerve Block., Saphenous Nerve Block., Post Operative Analgesia Duration.
- Trial name
- NCT01759524
- Testing
- Bupivacaine, Lidocaine
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Cork University Hospital
Hip Fracture
Femoral Nerve Block With Bupivacaine and Adjuvant Dexamethasone in Patients With Hip Fracture
Prolongation of the analgesic effect of a femoral nerve block from the present 15 hours to 24 hours in patients with hip fracture would have a major impact in order to provide better preoperative analgesia for this group.
- Trial name
- NCT02248870
- Testing
- Dexamethasone, Saline
- Where
- Denmark
- Volunteers
- 7 people
- Sponsor
- University of Aarhus
Pain, Appendicitis
Laparoscopic Transversus Abdominis Plane Block (LTAP) for Appendicectomy Versus Standard Port Site Treatment
This study aims to compare Laparoscopic assisted LTAP (Transversus Abdominis Plane) to standard port-site infiltration in terms of post-operative visual analogue scores (VAS) for pain at 3, 6, 12 and 24 hours following…
- Conditions
- Pain, Appendicitis, Surgery, Analgesia
- Trial name
- TapBlock (NCT05427266)
- Testing
- Tap Block - Bupivacaine
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Hip Fractures (ICD-10 72.01-72.2), Postoperative Pain Management After Total Hip Arthroplasty
Effect of Preoperative PENG Block on Spinal Anesthesia Positioning and Postoperative Analgesia in Hip Fracture Surgery
Hip fractures are among the most common orthopedic traumas, particularly in elderly patients, and are usually associated with significant pain during positioning for spinal anesthesia.
- Conditions
- Hip Fractures (ICD-10 72.01-72.2), Postoperative Pain Management After Total Hip Arthroplasty, Elderly Patients, Regional Anesthesia
- Trial name
- PENG-SPINE (NCT07194356)
- Testing
- Pericapsular nerve group (PENG) block, Standard Spinal Anesthesia (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Superior Trunk Block Versus Interscalene Block for Post-operative Analgesia in Shoulder Surgeries
Efficacy and Safety of Superior Trunk Block Versus Interscalene Block for Post-operative Analgesia in Shoulder Surgeries
Efficacy and safety of superior trunk block versus interscalene block for post-operative analgesia in shoulder surgeries
- Trial name
- NCT05978427
- Testing
- interscalene block, superior trunk block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
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