Clinical trials: Bupivacaine
Lung Cancer, Acute Pain
US-Guided Serratus Anterior Plane Block Versus Thoracic Epidural in Patients Undergoing Thoracotomy
Thoracic surgeries is known to be one of the most painful surgeries . Multiple analgesic techniques have been used for post operative analgesia including Thoracic epidural , Patient Controlled Analgesia and systemic opioids.
- Conditions
- Lung Cancer, Acute Pain, Chronic Pain
- Trial name
- NCT05672394
- Testing
- Continuous Serratus anterior plane block, Thoracic Epidural, Bupivacaine
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- National Cancer Institute, Egypt
Discharge Time, Spinal Anesthesia
Regional Anesthesia in Ambulatory Endovenous Ablation Surgery
Varicose veins represent irreversible, abnormal dilatations of the venous structures. They manifest as tortuous, swollen vessels visible beneath the skin of the lower extremities, particularly the feet and legs.
- Conditions
- Discharge Time, Spinal Anesthesia, Ambulatory Surgery, Femoral Nerve Block
- Trial name
- NCT07297082
- Testing
- Femoral nerve block, Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara Etlik City Hospital
Erector Spinae Block, Bariatric Surgery Candidate
Erector Spinae Block Versus Transversus Abdominis Plane Block In Laparoscopic Bariatric Surgery
The purpose of this study to compare erector spinae block to transversus abdominis plane block in bariatric surgeries regarding analgesic efficacy and postoperative oxygenation and respiratory complications
- Trial name
- NCT04417179
- Testing
- transversus abdominis block, Erector spinae block, Bupivacaine 0.25% Injectable Solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Postoperative Pain
Pilot Herniorrhaphy Study for Postoperative Analgesia
A Phase 2, Randomized, Pilot Study to Investigate the Safety, Efficacy, Pharmacokinetics and Bioavailability of HTX-011, HTX-002, or HTX-009 Administered Via Injection and/or Topical Application Following Unilateral Open Inguinal…
- Trial name
- NCT02504580
- Testing
- HTX-011, HTX-002, Bupivacaine HCI (Marcaine)
- Where
- 3 sites in United States
- Volunteers
- 463 people
- Sponsor
- Heron Therapeutics
Pain, Postoperative
Effects of TTPB vs PIFB on Opioid Consumption in Patients After Cardiac Surgery.
The objective of this study is to compare the effects of TTPB vs PIFB on postoperative opioid consumption in patients undergoing open cardiac surgery.
- Trial name
- NCT05627869
- Testing
- Transversus thoracic plane block, Pecto intercostal fascial block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Beni-Suef University
Postoperative Pain Management in Total Knee Arthroplasty
Genicular vs IPACK Block for Analgesia in Knee Arthroplasty
Total knee arthroplasty (TKA) is one of the most frequently performed orthopedic procedures, and with the aging population, the global number of TKA cases is expected to increase sixfold within the next decade.
- Trial name
- NCT07171931
- Testing
- IPACK block, Genicular nerve block with bupivacaine
- Volunteers
- 72 people
- Sponsor
- Kocaeli University
Analgesic Effect
Interpectoral-pectoserratus Plane Block for Minimally Invasive Aortic Valve Replacement Via Right Anterior Minithoracotomy
The goal of this clinical trial is to evaluate the analgesic effect of locoregional anaesthesia, specifically the interpectoral pectoserratus plane (IPP-PSP) block, in comparison to a placebo (sham block) after Aortic Valve…
- Trial name
- PAINCARE (NCT06369870)
- Testing
- Levobupivacaine Hydrochloride 0.25 % Injectable Solution, Sodium chloride 0.9%
- Where
- Belgium
- Volunteers
- 144 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Obesity
Ultrasound-Guided Erector Spinae Plane Block Following Laparoscopic Sleeve Gastrectomy Surgery
Bariatric surgery has been widely used in the treatment of obesity in recent years. It has been shown to be effective in reaching the ideal weight and reducing obesity-induced comorbidities.
- Trial name
- NCT03921970
- Testing
- ESP block (Group ESP)
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Analgesia
Dexmedetomidine Versus Magnesium Sulphate Added to Bupivacaine in Infraorbital Nerve Block for Perioperative Analgesia in Paediatric Patients for Cleft Lip Surgery
Regional analgesia is considered the cornerstone for postoperative analgesia in paediatric patients. One of the most common birth defects which require surgical intervention early in life is the cleft lip.
- Trial name
- NCT05624151
- Testing
- Dexmedetomidine +Bupivacaine, Magnesium Sulfate + Bupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Stress Urinary Incontinence, Surgical Incision
Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling Surgery
This study will compare the use of a dual-agent local analgesic (bupivacaine-meloxicam) for abdominal incisions in patients undergoing retropubic mid-urethral sling surgery to see if narcotic usage and pain are impacted.
- Conditions
- Stress Urinary Incontinence, Surgical Incision, Pain Vulva
- Trial name
- NCT05702827
- Testing
- Bupivacaine-Meloxicam
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- TriHealth Inc.
Total Knee Anthroplasty, Knee Osteoarthritis
IPACK vs Adductor Magnus Plane Block Added to Adductor Canal Block for Total Knee Arthroplasty
Total knee arthroplasty (TKA) is among the most frequently performed surgical procedures for degenerative joint diseases, including advanced knee osteoarthritis, rheumatoid arthritis, and post-traumatic arthritis.
- Conditions
- Total Knee Anthroplasty, Knee Osteoarthritis, Postoperative Pain Management
- Trial name
- NCT07643883
- Testing
- ACB+IPACK, ACB+AMM
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Knee Arthroplasty
Comparing Two Regional Anesthesia Interventions for Knee Arthroplasty.
Osteoarthritis of the knee is a common disease of the elderly and knee arthroplasty is indicated in severe cases to improve long term pain and function.
- Trial name
- NCT03944005
- Where
- 2 sites in Canada, United Kingdom
- Sponsor
- Western University, Canada
Pain
Preventive Analgesia in Multiparas Undergoing Induction of Labour
Our study is about providing a better birthing experience by placing and initiating epidural for labour pain before the contractions start.
- Trial name
- NCT00465231
- Testing
- bupivacaine, fentanyl, preservative free saline
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Muscle Weakness, Anesthesia
The Effect of Anesthesia on Perioperative Muscle Weakness and Neuro-endocrine Stress Response
The effect of surgery, in contrary to critical illness, on muscle weakness hasn't been thoroughly investigated. Recent data suggest that elective surgery may also induce muscle weakness.
- Conditions
- Muscle Weakness, Anesthesia, Anesthesia, Local, Surgery
- Trial name
- MUSCLE (NCT03600454)
- Testing
- General anesthesia, Spinal anesthesia, General anesthesia and epidural analgesia
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Ziekenhuis Oost-Limburg
Breast Cancer Surgery, Postoperative Pain, Acute
Chronic Pain in Post-Mastectomy Patients; The Difference Between Pectoral Nerve (PECS I-II) and Erector Spinal Plane (ESP) Blocks
This study looks at two types of injections (called PECS and ESP blocks) to see which one works better for reducing pain after breast cancer surgery (mastectomy).
- Conditions
- Breast Cancer Surgery, Postoperative Pain, Acute, Postoperative Pain, Chronic, Post-mastectomy Pain Syndrome
- Trial name
- NCT06900842
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Hacettepe University
Postdural Puncture Headache, Sphenopalatine Ganglion Block
Sphenopalatine Ganglion Block for Post-Dural Puncture Headache
The investigators are attempting to determine a less invasive method of treatment for postdural puncture headaches that can occur after regional anesthesia.
- Trial name
- NCT02181205
- Testing
- bupivacaine
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Cesarean Section (MeSH: D002585), Anesthesia, Spinal (MeSH: D000775)
Ultrasound Versus Palpation for Determining Spinal Puncture Level in Cesarean Section
This study compares two methods of identifying the correct intervertebral level before performing spinal anesthesia in women undergoing elective cesarean delivery.
- Conditions
- Cesarean Section (MeSH: D002585), Anesthesia, Spinal (MeSH: D000775), Hypotension (MeSH: D007022)
- Trial name
- USG-SPINE (NCT07789756)
- Testing
- Preprocedural ultrasound level identification, Landmark palpation level identification
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Quadroiliac Plane Block, Transmuscular Quadratus Lumborum Block
Quadroiliac Plane Block Versus Transmuscular Quadratus Lumborum Block for Postoperative Analgesia After Total Hip Arthroplasty
This study aims to evaluate and compare the postoperative analgesic efficacy, opioid consumption, motor function preservation, and quality of recovery of ultrasound-guided Quadroiliac Plane Block (QIPB) versus transmuscular…
- Conditions
- Quadroiliac Plane Block, Transmuscular Quadratus Lumborum Block, Postoperative Analgesia, Total Hip Arthroplasty
- Trial name
- NCT07815145
- Testing
- Quadroiliac Plane Block, Transmuscular quadratus lumborum block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Inguinal Herniorrhaphy, Pain, Postoperative
Post-Operative Analgesic Effects of Local Wound Infiltration With Ketorolac After Inguinal Herniorrhaphy
Inguinal hernia is one of the most common diseases worldwide, including Thailand. Patients who underwent treatment of inguinal hernia (herniorrhaphy) found surgical site pain.There are many procedures to relieve pain after…
- Trial name
- NCT03534505
- Testing
- Ketorolac group, Bupivacaine group
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Mahidol University
Intraperitoneal Magnesium Sulphate in Laparoscope in Pediatrics
Intraperitoneal Magnesium Sulphate and Bupivacaine Versus Intravenous Analgesia in Laparoscopic Surgeries in Pediatrics
The investigators are going to study the analgesic efficacy of intraperitoneal instillation of a combination of Magnesium sulphate with bupivacaine versus ordinary used parenteral analgesics for pain relief after laparoscopic…
- Trial name
- NCT04651556
- Testing
- Magnesium Sulfate & bupivacaine, paracetamol & ketorolac
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Menoufia University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.