Clinical trials: Bupivacaine
Facial Plane Blocks
Comparison of the Efficacy of One Level and Tow Level of Bilateral Thoracic Erector Spinae Plane Block Combined With General Anesthesia in Laparoscopic Bariatric Surgery for Obese Patients: Randomized Controlled Trial
comparison of the feasibility and efficacy of the one-level and two-level thoracic ESP block and their effect on intraoperative and postoperative analgesia in bariatric surgeries.
- Trial name
- NCT06811493
- Testing
- bilateral thoracic erector spinae plane block combined with general anesthesia in laparoscopic bariatric surgery in obese patients
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Serratus Plane Block, Postoperative Hyperalgesia
Effect of Liposome Bupivacaine Serratus Plane Block on Postoperative Hyperalgesia and Chronic Post-surgical Pain in Patients Undergoing Radical Mastectomy
Radical mastectomy is currently the mainstream surgical treatment for breast cancer. Patients often experience significant postoperative pain, and some may develop chronic pain.
- Conditions
- Serratus Plane Block, Postoperative Hyperalgesia, Chronic Post-surgical Pain, Liposomal Bupivacaine
- Trial name
- NCT07289178
- Testing
- Serratus Plane block (single injection)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Postoperative Pain
Liposomal Bupivacaine vs. Bupivacaine Hydrochloride and Lidocaine During Suburethral Sling Placement
Postoperative pain, the quality of their recovery and the opioid consumption following a midurethral sling placement are being compared between 2 groups.
- Trial name
- NCT02875015
- Testing
- Liposomal Bupivacaine, Bupivacaine Hydrochloride and Lidocaine, Suburethral Sling
- Where
- 2 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Urethral Stricture, Male
Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty
Patients undergoing buccal urethroplasty will often have significant post-operative oral pain from the graft site. Various graft harvest techniques and methods for post-harvest hemostasis including graft site closure have been…
- Trial name
- Buccal (NCT05300685)
- Testing
- Standard Buccal Harvest, Basic buccal procedure + Long acting local, Basic buccal procedure + Buccal block
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Chronic Shoulder Pain
Exparel for Total Shoulder Pain
Total shoulder surgery (arthroplasty) is a widely successful method of treating shoulder arthritis. Although the goal of the procedure is pain relief, post-operative pain is unavoidable.
- Trial name
- ETSP (NCT03739021)
- Testing
- Exparel, Ropivacaine
- Volunteers
- 60 people
- Sponsor
- University of South Florida
Intraoperative Hypotension, Spinal Aneshtesia
Dural Sac Area-Guided Spinal Anesthesia Dosing for TURP
This randomized controlled study will evaluate whether individualizing the dose of spinal anesthesia according to the ultrasound-derived dural sac cross-sectional area (DSCSA) can improve hemodynamic stability in patients…
- Conditions
- Intraoperative Hypotension, Spinal Aneshtesia, TURP(Transurethral Resection of Prostate)
- Trial name
- NCT07794852
- Testing
- DSCSA-Guided Individualized Spinal Anesthesia Dosing, Bupivacaine, Fentanyl (FEN)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Postoperative Pain, Chronic Post Operative Pain
Comparative Analysis of Three Locoregional Anesthesia Methods in Breast Tumour Pathology Surgery
The present study compares the Erector Spinae Plane (ESP) block, Pectoral (PECS II) block, and Serratus-Intercostal Fascial Plane (SIFP) block.
- Conditions
- Postoperative Pain, Chronic Post Operative Pain, Breast Tumor, Locoregional Anesthesia
- Trial name
- NCT05185752
- Testing
- SIFP Block Locoregional Interfascial Anesthesic Technique, PECS II block: Locoregional Interfascial Anesthesic Technique, ESP block: Locoregional Interfascial Anesthesic Technique
- Where
- Spain
- Volunteers
- 103 people
- Sponsor
- University of Valencia
Rheumatism Knee
Single Shot Versus Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty
Adductor canal block (ACB) has emerged as an option for postoperative regional analgesia in patients undergoing total knee arthroplasty (TKA).
- Trial name
- NCT04986878
- Testing
- single-shot adductor canal block
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Aswan University Hospital
Analgesia
Liposomal Bupivacaine Versus Non-liposomal Bupivacaine for Total Shoulder Arthroplasty
The objective of this study is to validate the analgesic efficacy of admixed Liposomal bupivacaine (LB) + bupivacaine compared with plain bupivacaine when injected for interscalene nerve block (ISNB) for total shoulder…
- Trial name
- NCT04974385
- Testing
- Liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Dexmedtomidine in Erector Spinae Block for Laparscopic Cholecystectomy
Dexmetomidine With Erector Spinae Plane Block in Cholecystectomy
Sixty patients scheduled for elective laparoscopic cholecystectomy will be randomly assigned using sealed envelope into two equal groups (30 patients each).
- Trial name
- NCT05369468
- Testing
- dexmedetomidine as adjuvant with bupivacaine, Bupivacain only
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Post-operative Pain, Acute, Opioid Use
Are Adductor Canal Blocks With Bupivacaine and Added Magnesium Better at Managing Post-operative Pain Than Bupivacaine and Added Buprenorphine in Patients Undergoing Same-day Discharge Total Knee Arthroplasty?
The purpose of this study is to compare the use of magnesium and bupivacaine to buprenorphine and bupivacaine in post-operative adductor canal blocks (ACB); the study will determine if one combination can result in decreased…
- Trial name
- NCT05091138
- Testing
- Adding Magnesium as an adjuvant to Bupivacaine in the adductor canal block (ACB) for same-day discharge total knee arthroplasty, Adding Buprenorphine as an adjuvant to Bupivacaine in the adductor canal block (ACB) for same-day discharge total knee arthroplasty
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wayne State University
Postoperative Pain
Analgesia in Knee Arthroscopic Surgery
Pain relief in knee Arthroscopic Surgery is essential for rapid recovery of function.
- Trial name
- NCT02818985
- Testing
- Dexamethasone, Dexmedetomidine, Saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Postoperative Opioid Requirements in Patients With Traumatic Fracture Hip
Fascia Iliaca Versus Quadratus Lumborum Block for Pain Management in Total Hip Replacement.
Postoperative analgesia is essential for early ambulation of patients with hip arthroplasties as well as decreasing hospital stay time.
- Trial name
- NCT05504525
- Testing
- Fascia Iliaca block, Quadratus lumborum block
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Ain Shams University
Shoulder Arthroscopy, Peripheral Nerve Block
Comparison of the Postoperative Analgesic Efficacy of SPSIPB and ISBPB
Shoulder arthroscopy is one of the common surgical procedures performed today. After shoulder surgery, providing adequate analgesia is necessary for both the comfort of the patient and the ability to perform the necessary…
- Conditions
- Shoulder Arthroscopy, Peripheral Nerve Block, Pain Management
- Trial name
- NCT06626191
- Testing
- Interscalene brachial plexus block, Serratus posterior superior intercostal plane block, Group without peripheral nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Etlik City Hospital
Anesthesia, Conduction, Surgery
A Randomised Comparison on the Dose Requirement Between, Levobupivacaine, Ropivacaine and Bupivacaine in Intrathecal Anaesthesia
To determine and compare the effective intrathecal dose of levobupivacaine, ropivacaine and bupivacaine for 50% of patients in lower limb surgery
- Trial name
- NCT00636974
- Testing
- Combined spinal epidural anaesthesia
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Hospital Authority, Hong Kong
Genital Neoplasm Malignant Female, Surgical Procedure, Unspecified
A Trial Comparing Surgeon-administered TAP Block With Placebo After Midline Laparotomy in Gynecologic Oncology
Multimodal opioid-sparing analgesia is recommended in order to prevent post-operative complications and shorten length of stay. Administration by the surgeon of local anesthetics in the abdominal wall after surgery for a…
- Trial name
- NCT04202874
- Testing
- Surgeon-administered transversus abdominis plane (TAP)
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- McMaster University
Laparotomy, Colectomy
QL Block With Exparel in Colectomy
The purpose of this study is to determine if using a different type of injection of local anesthestic (pain medicine) in between the muscle layers of the abdominal wall (called a quadratus lumborum block) will improve pain…
- Trial name
- NCT03827291
- Testing
- Exparel, Thoracic epidural analgesia
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Duke University
Analgesia
Effect of Auto-Bolus Interval on Analgesic Quality During Labor Analgesia With Dural Puncture Epidural
It is aimed in this study to compare the effect of changing the interval time for programmed auto boluses of local anaesthetics on the total anesthetic consumption and quality of labor analgesia with dural puncture epidural…
- Trial name
- NCT06329713
- Testing
- Group I: 30 Min Interval Time, Group II: 60 Min Interval Time
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Pain, Postoperative
Effect of Unilateral Erector Spinae Plane Block Versus Intrathecal Morphine on Early Mobilization After Hip Replacement
Preoperative assessment: Patients who fulfill inclusion criteria will be evaluated by medical history, physical examination and clinical laboratory tests which are a complete blood picture (CBC), kidney function tests, liver…
- Trial name
- NCT06621849
- Testing
- erector spinae plane block, Morphine
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lumbar Spinal Stenosis
Comparison of the Order of Treatment in Lumbar Spinal Stenosis
Patients with back pain with spinal stenosis of the lower back will be asked to volunteer for this research study. These patients don't need immediate surgery for this problem.
- Trial name
- NCT02103543
- Testing
- physical therapy, lumbar interlaminar epidural steroid injection, epidural steroid injection
- Where
- United States
- Sponsor
- Emory University
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