Clinical trials: Bupivacaine
Post-Dural Puncture Headache, Hypotension
Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section
The goal of this clinical trial is to compare different approaches of spinal anesthesia in pregnant females who are having cesarean section.
- Conditions
- Post-Dural Puncture Headache, Hypotension, Spinal Shock, Hematoma
- Trial name
- NCT05637645
- Testing
- Midline Approach, Paramedian Approach, Taylors approach
- Where
- 4 sites in Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bahawal Victoria Hospital Bahawalpur
Post Operative Pain
Dexmedetomidine as an Adjuvant to Bupivacaine in Bilateral PECs for Pain Control After Cardiac Surgeries
the study aims to test the quality of analgesia provided by dexmedetomidine as an adjuvant to bupivacaine bilateral PECs block in patients scheduled for cardiothoracic surgeries with median sternotomy incision.
- Trial name
- PECs (NCT06453681)
- Testing
- bilateral PECS, Dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Comparison of Anterior Sciatic Nerve Block and Adductor Magnus Muscle Plane Block for Anterior Cruciate Ligament Surgery
Anterior cruciate ligament (ACL) reconstruction is frequently associated with moderate-to-severe postoperative pain despite its arthroscopic nature, owing to the complex sensory innervation of the knee involving the femoral…
- Trial name
- NCT07601529
- Testing
- Adductor canal block, Anterior sciatic nerve block, Adductor magnus plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ataturk University
Anesthesia, Spinal, Cesarean Section
Changes in Cardiac Output During Cesarean Delivery Under Spinal Anesthesia
Cardiac output will be measured in healthy parturients undergoing cesarean delivery under spinal anesthesia
- Conditions
- Anesthesia, Spinal, Cesarean Section, Echocardiography, Cardiac Output
- Trial name
- NCT05269537
- Testing
- Transthoracic Echocardiography, Spinal Anesthesia, Intrathecal Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Oropharyngeal Cancer, Dysphagia, Oropharyngeal
Liposomal Bupivacaine and Transoral Robotic Surgery
This study is for patients with oropharyngeal squamous cell carcinoma. We want to learn more about how we can optimize pain control in patients who undergo transoral robotic surgery (TORS) for oropharyngeal squamous cell…
- Conditions
- Oropharyngeal Cancer, Dysphagia, Oropharyngeal, Post Operative Pain, Transoral Robotic Surgery
- Trial name
- NCT05862792
- Testing
- Liposomal bupivacaine
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Geisinger Clinic
Analgesia, Surgery
U/S-guided Continuous Quadratus Lumborum Block III in Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is considered to be the first choice and a more conservative procedure than open stone surgery.
- Conditions
- Analgesia, Surgery, Renal Stone
- Trial name
- NCT04800302
- Testing
- Continous Quadratum Lumborum Block III, Single dose Quadratum Lumborum Block III, Intra-venous Morphine
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Nazmy Edward Seif
Analgesia
Adductor Canal Block in Total Knee Arthroplasty
The purpose of this study is to evaluate whether adding ketamine to bupivacaine is superior to bupivacaine alone in terms of providing better pain control for 48 hours postoperatively after TKA.
- Trial name
- NCT05715437
- Testing
- Bupivacaine plus Normal Saline, Bupivacain and ketamine
- Volunteers
- 60 people
- Sponsor
- Assiut University
Arthroscopic Shoulder Surgery
A Comparison of ESP Block to SSN Block for Analgesia in Shoulder Surgery
A comparison between Erector Spinae Plane block and Suprascapular nerve block in providing analgesia for shoulder surgery
- Trial name
- NCT04669639
- Testing
- Block procedures for shoulder surgery analgesia
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Zagazig University
Acute Pain, Chronic Pain
Effect of Locally Administered Morphine and Bupivicaine on Acute and Chronic Postmastectomy Pain
This study investigate the effect of addition morphine to locally instillation bupivacaine on developing chronic neuropathic pain acute postoperative pain after breast cancer surgery and on the probability of developing chronic…
- Trial name
- NCT02462577
- Testing
- local instillation of morphine to surgical wound
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Opioid Consumption, Postoperative
Dexmedetomidine as an Adjuvant to Bupivacaine for Ultrasound-Guided External Oblique Intercostal Block
Effect of Adding Dexmedetomidine as Adjuvant toBupivacaine in Ultrasound Guided ExternalOblique Intercostal Plane Block in UpperAbdominal Cancer Surgery.
- Trial name
- Dexmedetomidin (NCT07263165)
- Testing
- Dexmedetomidine
- Volunteers
- 54 people
- Sponsor
- Assiut University
Post-operative Pain
Ultrasound Guided Erector Spinae Plane Block in Patients Undergoing VATS Lobectomy
This study will compare ESP block plus patient-controlled analgesia (PCA) to intercostal nerve block plus PCA as post-operative pain control for patients having video-assisted thorascopic surgeries.
- Trial name
- NCT03176667
- Testing
- Ultrasound guided erector spinae plane block, Intercostal block
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University
Pain, Postoperative
Pre-incision Versus Post-incision Local Anesthetic During Robotic Sacrocolpopexy
Obtaining Likest-pain scale score on postoperative day one after injection of local anesthetic into incision sites of a laparoscopic/robotic-assisted sacrocolpopexy
- Trial name
- CLAPPS (NCT04996251)
- Testing
- Bupivacaine Injection
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Radial Artery Cannulation
Comparative Study Between the Effect of Ultrasound Guided Median Nerve Block , Radial Nerve Block and Local Infiltration on Feasibility of Radial Artery Cannulation
Arterial line placement is often needed in various critical care settings. It is a basic procedure performed for continuous blood pressure (BP) monitoring and rapid access for repeated arterial blood gas samples, as it is…
- Trial name
- NCT05459792
- Testing
- median nerve block, radial nerve block, local infiltration
- Where
- 2 sites in Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Pain
Comparison of Efficacy of Bupivacaine in Supraclavicular Block With or Without Dexmedetomidine
End-stage renal disease (ESRD) patients are coming for Brachial vein transposition surgery. Patients were randomly allocated using sealed opaque envelope bearing A- (Injection bupivacaine (0.25%) 28 ml plus 2 ml.
- Trial name
- NCT05991375
- Testing
- DEXmedetomidine, saline
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Pain Control
Efficacy of Local Anesthetic Through Continuous Infusion
Efficacy of using continuous infusion of local anesthetic for post operative pain control following laparotomy.
- Trial name
- NCT04173312
- Testing
- Bupivacaine infusion, Saline
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Ascension Health
Epiphora, Ptosis
Bupivacaine Epiphora Trial
The objective of this study is to investigate quantitative improvement in excessive tearing after administration of Bupivacaine, a local anesthetic, into the affected eyelids.
- Trial name
- NCT03266081
- Testing
- 0.75% bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
Hallux Valgus, Surgery
Continuous Versus Automated Bolus Infusion in Sciatic Nerve Catheters
This study is developed to determine if the local anaesthetic dose can be reduced by the use of intermittent bolus technique compared to continuous infusion when the nerve catheter is placed underneath the paraneurium by…
- Trial name
- NCT02293330
- Testing
- continuous infusion of levobupivacaine, Intermittent bolus infusion of levobupivacaine
- Where
- Belgium
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Postoperative Pain
Comparison of Interpectoral+Serratus Anterior Block With Erector Spinae Block in Minimally Invasive Cardiac Surgery
Adequate pain management after minimally invasive cardiac surgery is essential for early ambulation and patient satisfaction. However, an incision similar to thoracotomy surgery is made by entering between the ribs, and a…
- Trial name
- NCT05743231
- Testing
- interpectoral area block + serratus anterior area block group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Postoperative Pain
NSAIDs With Morphine-PCA Compared to Epidural Analgesia in Thoracotomy Pain
The investigators investigated whether a strictly controlled pain management with patients participating in a clinical study can attenuate persistence of post-thoracotomy pain.
- Trial name
- NCT01541137
- Testing
- Diclofenac, parecoxib/ valdecoxib, patient controlled epidural analgesia
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Helsinki University Central Hospital
Pain, Postoperative
Modified TAP (Transverse Abdominis Plane) Block in Colorectal Surgery
Single Blind, Randomized Controlled study to see if TAP Block with Exparel provides better pain relief than TAP Block with bupivicaine.
- Trial name
- NCT04781075
- Testing
- Pain Scale, Exparel Injectable Product, Bupivacaine Injection
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
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