Clinical trials: Bupivacaine
Lumbar Spine Surgery, Erector Spinae Plane Block
Effect of ESPB on Intraoperative Remifentanil Consumption
In recent years, regional anesthesia techniques have also been frequently applied to patients for pain relief. Erector spinae plane block (ESPB), is among the regional anesthesia techniques frequently used in lumbar spine…
- Conditions
- Lumbar Spine Surgery, Erector Spinae Plane Block, Remifentanil Consumption
- Trial name
- NCT06303557
- Testing
- Preoperative Erector Spinae Plane Block, Postoperative Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Neuromuscular Blockade, Regional Anesthesia
Bilateral Transversus Abdominis Plane Block Versus Atracurium During Laparoscopic Gynecology Procedures.
A monocentric, prospective, randomized controlled trial, including patients proposed for a laparoscopic gynecologic surgery comparing the muscular relaxing effect of a bilateral ultrasound-guided Transversus Abdominis Plane block…
- Trial name
- NCT03701256
- Testing
- Bilateral ultrasound guided TAP bloc, Neuromuscular blockade agent: Atracurium 01mg/kg per bolus
- Where
- Tunisia
- Volunteers
- 100 people
- Sponsor
- University Tunis El Manar
Dexmedetomidine, Craniotomy
Dexmedetomidine as an Adjuvant to Bupivacaine in Scalp Block vs Bupivacaine Alone for Hemodynamics Stability in Craniotomy
The investigator tested the effect of dexmedetomidine as an adjuvant to bupivacaine compared to bupivacaine alone in mean arterial pressure stability in adult patients undergoing craniotomy
- Conditions
- Dexmedetomidine, Craniotomy, Regional Anesthesia, Mean Arterial Pressure Stability
- Trial name
- NCT06951256
- Testing
- Scalp block with bupivacaine alone, Scalp block by adding dexmedetomidine as an adjuvant to bupivacaine
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Laryngeal Neoplasm
The Efficacy of Superficial Cervical Block Application in Postoperative Analgesia Management in Patients Undergoing Total Laryngectomy and Bilateral Neck Dissection
The goal of this clinical trial is to evaluate the efficacy of the superficial cervical block in postoperative pain management for patients undergoing total laryngectomy and bilateral neck dissection.
- Trial name
- NCT06852651
- Testing
- Superficial Cervical Block (SCB) Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Postoperative Pain, Cholecystectomy, Laparoscopic
Recto-Intercostal Fascial Plane and External Oblique Intercostal Blocks for Pain in Laparoscopic Cholecystectomyin Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is a common surgical procedure that can cause significant postoperative pain, particularly originating from trocar insertion sites.
- Trial name
- NCT07777172
- Testing
- Group EOIPB (External Oblique Intercostal Plane Block), Group EOIPB + RIFPB (Combined Blocks)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Etlik City Hospital
Postoperative Pain
Indications of Erector Spinae Plane Block in Pediatric Patients
Patients who were operated by Department of Pediatric Surgery between the 1 September 2017 and 28 February 2019 and who received erector spinae plane blocks as a part of postoperative analgesia management will be scanned.
- Trial name
- NCT03906019
- Testing
- ESP Block, FLACC score, NRS score
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people
- Sponsor
- Kocaeli University
Hip Fractures
Anesthesia And Post-operative Mortality After Proximal Femur Fractures
This study evaluates the effect of anesthesia on mortality after surgical repair of proximal femur fracture. Patients will receive either a subarachnoid block or a combination of peripheral nerve blocks and light general…
- Trial name
- NCT02406300
- Testing
- Subarachnoid Anesthesia, PNB/GA, ropivacaine
- Where
- Portugal
- Volunteers
- 57 people
- Sponsor
- Centro Hospitalar do Porto
Osteoarthritis, Pain, Postoperative
Liposomal Bupivacaine Versus Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Total Knee Arthroplasty
The purpose of this study is to compare the efficacy and duration of pain relief after total knee arthroplasty provided by a single injection of liposomal bupivacaine (EXPAREL®) versus standard bupivacaine with an adjuvant…
- Trial name
- NCT02624856
- Testing
- Liposomal bupivacaine, Bupivacaine plus dexamethasone
- Where
- United States
- Sponsor
- Albany Medical College
Pain, Acute, Opioid Use
Femoral Triangle Block With Popliteal Plexus Block Versus Femoral Triangle Block Versus Adductor Canal Block for TKA
In this study we wish to investigate the analgesic effect 3 different nerve block regimes in patients following primary total knee arthroplasty (TKA).
- Conditions
- Pain, Acute, Opioid Use, Analgesia
- Trial name
- NCT04854395
- Testing
- Marcain 5 mg/ml
- Where
- Denmark
- Volunteers
- 165 people
- Sponsor
- Regionshospitalet Silkeborg
Total Knee Anthroplasty
Ultrasound Guided Combined Adductor Canal, Superior Genicular Nerves and Anterior Femoral Cutaneous Nerves Blocks in Comparison With Periarticular Local Anesthesia Infiltration in Primary Total Knee Arthroplasty
Background: Pain management in total knee arthroplasty continues to evolve especially as an early postoperative analgesia is of paramount importance in achieving patient satisfaction and improving clinical outcomes.
- Trial name
- NCT07705230
- Testing
- Periarticular Infiltration, Ultrasound-Guided Triple Block Technique
- Where
- Saudi Arabia
- Volunteers
- 112 people
- Sponsor
- SAMEH ELSHERBINI
Pain, Postoperative
Pericapsular Nerve Group Block Versus Caudal Block for Postoperative Pain Management in Pediatric Hip Surgery
Children can experience substantial pain after hip operations, causing agitation, depression, and sleep disruption, which can have a negative impact on their health.
- Trial name
- NCT06563622
- Testing
- Pericapsular Nerves Group Block, Caudal Epidural Block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Benha University
Hip Fractures, Hip Injuries
Iliopsoas Plane Block vs PENG Block for Hip Arthroplasty
Hip arthroplasty is one of the most common orthopedic procedures especially in elderly patients due to deformation of joints. Patients may complain of severe pain due to surgical trauma and prosthesis.
- Conditions
- Hip Fractures, Hip Injuries, Hip Arthropathy
- Trial name
- NCT05397145
- Testing
- Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Analgesia
Ultrasound Guided Block for Postoperative Analgesia in Arthroscopic Shoulder Surgery
This study aimed to compare the efficacy of high thoracic-ESPB with shoulder block as analgesic options for arthroscopic shoulder surgery. Primary outcome: 24-hour analgesic consumption.
- Trial name
- NCT06202430
- Testing
- High Thoracic Erector Spinae Plane Block, Shoulder Block
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Macular Holes, Intraocular Lens Opacification
Oral Sedation in Vitreoretinal Surgery
The purpose of this study is to compare the efficacy of oral sedation to intravenous sedation with anesthesiology support and monitoring.
- Conditions
- Macular Holes, Intraocular Lens Opacification, Vitrectomy, Vitreous Hemorrhage
- Trial name
- NCT04346095
- Testing
- Oral Sedatives with or Without Analgesia, Intravenous Sedatives with or Without Analgesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rocky Vista University, LLC
İnguinal Hernia, Post Operative Pain
Comparison of QLB and TFP Block for Postoperative Analgesia in Laparoscopic Inguinal Hernia
This randomized controlled trial aims to compare the effects of ultrasound-guided lateral Quadratus Lumborum Block (QLB) and Transversalis Fascia Plane (TFP) block on postoperative analgesia in patients undergoing laparoscopic…
- Trial name
- NCT07604259
- Testing
- Lateral Quadratus Lumborum Block, Transversalis Fascia Plane Block, Port Site Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Pain
Open-Label CA-008 (Vocacapsaicin) in Bunionectomy
A Phase 2, open-label study of CA-008 to evaluate post-surgical pain control with CA-008.
- Trial name
- NCT03885596
- Testing
- CA-008, Ketorolac, Acetaminophen IV
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Concentric Analgesics
Pain
Parasternal Nerve Block Using Bupivacaine for Postoperative Analgesia in Children Undergoing Cardiac Surgery
All pediatric patients who undergo cardiac surgery require analgesic medications for postoperative pain control and many require sedation to facilitate comfort with cares.
- Trial name
- NCT02512861
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Knee Osteoarthritis
Effectiveness of Ultrasound Guided Adductor Canal Block on Chronic Pain in Knee Osteoarthritis
Adductor canal block has become popular as effective mean for pain relief following knee surgery.This block has not been checked in chronic pain patients.The purpose of this study is to assess the efficacy and safety of adductor…
- Trial name
- NCT02695654
- Testing
- Levobupivacaine, Clonidine
- Where
- Slovenia
- Volunteers
- 77 people
- Sponsor
- Mensur Salihovic
Pain Management
The Effect of Adding PIFP Block to SAP Block on Postoparative Pain Management in Patient Planned for Breast Surgery
the study is a clinical study that will be conducted on women between the ages of 18 and 75 who are scheduled for breast surgery.
- Trial name
- NCT06129383
- Testing
- serratus anterior plane block and pectointercostal plane block in breast surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uludag University
TAP Block, Caesarean Section
Fixed-Mass Different Volumes Bupivacaine TAP Block After Cesarean
Cesarean section is commonly associated with moderate to severe postoperative pain, which may delay mobilisation, impair breastfeeding, and affect mother-infant bonding.
- Conditions
- TAP Block, Caesarean Section, Postoperative Pain
- Trial name
- NCT07616180
- Testing
- Bupivacaine
- Volunteers
- 50 people
- Sponsor
- Cairo University