Clinical trials: Bupivacaine
Coronary Arterial Disease (CAD), Serratus Anterior Muscle Plane Block
Comparison of the Analgesic Efficacy of Chest Wall Blocks in Coronary Artery Bypass Surgery
In this study, the analgesic effects of the Transverse Thoracic Muscle Plane Block and deep Serratus Anterior Plane versus deep and superficial Serratus Anterior Plane applications, which will be performed under ultrasound…
- Conditions
- Coronary Arterial Disease (CAD), Serratus Anterior Muscle Plane Block, Transversus Thoracis Muscle Plane Block, Postoperative Analgesia
- Trial name
- NCT06657261
- Testing
- The patient group receiving deep and superficial serratus anterior plane block, The patient group receiving a combination of deep serratus anterior plane block and transverse thoracic muscle plane block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Post Spinal Shivering
Dexmedetomidine and Fentanyl As Adjuvants to Hyperbaric Bupivacaine for the Prevention of Post-spinal Shivering in Hip Arthroplasty Surgeries
The aim of this study is to compare the efficacy of intrathecal dexmedetomidine versus intrathecal fentanyl when added to hyperbaric bupivacaine in the prevention of post-spinal shivering in patients undergoing hip arthroplasty…
- Trial name
- NCT06834841
- Testing
- Dexmedetomidine, Fentanyl
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Thoracic Diseases
Comparison of Postoperative Analgesic Consumption of the Erector Spina Plane Block and Serratus Anterior Plane Block
To evaluate the ability of Erector spina Plane block and Serratus Anterior Plane block to decrease postoperative pain and analgesia requirements in patients undergoing thoracotomy.
- Trial name
- NCT03904082
- Testing
- Erector Spinae Plane block ( Group ı), Serratus Anterior Plane block ( Group ıı), Control Group (GROUPIII)
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- TC Erciyes University
Dexmedetomidine, Intrathecal
Dexmedetomidine as an Intrathecal Adjuvant to Hyperbaric Bupivacaine for Postoperative Analgesia in Patients Undergoing Arthroscopic Anterior Cruciate Ligament Reconstruction Surgeries
This study aimed to evaluate the effect of adding low doses of dexmedetomidine to hyperbaric bupivacaine during spinal anesthesia on post operative analgesia characteristics in Arthroscopic Anterior Cruciate Ligament…
- Conditions
- Dexmedetomidine, Intrathecal, Adjuvant, Hyperbaric Bupivacaine
- Trial name
- NCT06667024
- Testing
- Hyperbaric bupivacaine, Dexmedetomidine and Hyperbaric bupivacaine
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Tanta University
Nerve Block, Pain, Postoperative
TAP vs. ESP Block for Gynecological Post Operative Pain
The goal of this double blind randomized controlled trial is to compare transversus abdominis plane block and erector spinae plane block in gynecological surgery patients.
- Trial name
- NCT06044779
- Testing
- Transversus Abdominis Plane Block using 0.25% Bupivacaine, Erector Spinae Plane Block using 0.25% Bupivacaine
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Padjadjaran
Analgesia, Postoperative
Exparel vs. Bupivacaine Hydrochloride vs. Placebo for Hernia Repair
Patients usually experience some level of pain after their hernia repair. To control pain after the operation, surgeons have many options.
- Trial name
- NCT03541941
- Testing
- Exparel, Bupivacaine Hcl 0.25% Inj
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- The Cleveland Clinic
Umbilical Hernia
Caudal Versus Rectus Sheath Study
The literature has clearly demonstrated that the effective treatment of postoperative pain in infants and children is challenging.
- Trial name
- NCT01394523
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Nationwide Children's Hospital
Laparoscopic Cholecystectomy Surgery
Intraperitoneal Ketamine Versus Bupivacaine for Postoperative Pain Control After Laparoscopic Cholecystectomy
The intraperitoneal approach is used in anesthesia to manage the pain associated with abdominal procedures. Few studies have been conducted comparing intraperitonela ketamine with bupivacaine for pain control in laparoscopic…
- Trial name
- NCT06807554
- Testing
- Ketamine, Bupivacaine
- Where
- Pakistan
- Volunteers
- 92 people
- Sponsor
- Liaquat National Hospital & Medical College
Post Operative Pain
Postoperative Anelgesic Effect of Rhomboid Intercostal Nerve Block Versus Erector Spinae Plane Block
Despite of analgesic effect of intravenous analgesic medications at intraoperative and postoperative time , The regional anesthetic techniquehas more benefits suchbetter control of Acute pain and hence less chronic pain and…
- Trial name
- NCT05452369
- Testing
- Rhomboid intercostal plane block
- Where
- 2 sites in Egypt
- Volunteers
- 104 people
- Sponsor
- ghada fouad
Postoperative Pain
Modified Pectoral Nerve Block Vs Thoracic Erector Spinae Plane Block for Analgesia for Aesthetic Breast Surgeries
The aim of this study is to evaluate The Effectiveness of Ultrasound Guided Modified Pectoral Nerve Block (PECS II) versus Thoracic Erector Spinae Plane Block (ESPB) for postoperative Analgesia in cases of aesthetic breast…
- Trial name
- NCT06478654
- Testing
- Bilateral Modified Pectoral Nerve Block (PECS II)., Bilateral Thoracic Erector spinae plane block (ESPB).
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia, Opioid Use
PROUD Study - Preventing Opioid Use Disorders
The objective of this study is to pilot an opioid free anesthetic protocol for patients undergoing total hip replacement.
- Trial name
- NCT04766996
- Testing
- Guided mindfulness exercises, Self-administered aromatherapy, Baby aspirin
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Emory University
Zygapophyseal Synovial Joint Cyst
Percutaneous Rupture of Zygapophyseal Joint Cysts
Lumbar zygapophyseal joint cysts can cause lower extremity radiculopathy. These cysts can be cured by a minimally invasive technique: percutaneous cyst distention and rupture
- Trial name
- NCT00837070
- Testing
- Percutaneous zygapophyseal cyst rupture
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- Ullevaal University Hospital
Mononeuropathy of the Median Nerve, Mild
Effect of Age on the Median Effective Concentration(EC50) for Motor Block With Spinal Plain Bupivacaine
This study was performed in 131 adult patients undergoing transurethral, urological or lower limb surgery under combined spinal and epidural anesthesia.
- Trial name
- NCT02141841
- Where
- China
- Sponsor
- China Three Gorges University, Yichang, China
Hip Surgery, Femoral Neck Fractures
Comparison of Lumbar Erector Spinae Plane Block and Spinal Anesthesia in Hip and Proximal Femur Surgery
Hip and proximal femur surgeries are commonly performed in elderly patients and require anesthetic techniques that provide adequate surgical anesthesia while minimizing the need for additional opioid administration.
- Trial name
- L-ESP-HIP Stud (NCT07427082)
- Testing
- Ultrasound-Guided Lumbar Erector Spinae Plane Block (L4), Spinal Anesthesia (L4-L5)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Gaziantep City Hospital
Hip Arthropathy
Anterior Iliopsoas Muscle Space Block Versus Supra-iliac Anterior Quadratus Lumborum Block in Total Hip Arthroplasty
Approximately 1.66 million hip fractures happen in a year worldwide. About 95% of these fractures happen in individuals older than 60 years.
- Trial name
- NCT05556759
- Testing
- control, IPS, Supra-iliac QL
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Zagazig University
Stress Urinary Incontinence
Evaluation of Postoperative Pain After Tension-free Obturator Tape Operation (TVT-O) With or Without Local Anesthetic
BACKGROUND: Compare the pain intensity after TVT-O procedure in the inner part of the thigh where the anesthetic substance will be injected versus the inner part of of the thigh without anesthetic injection in the same woman.
- Trial name
- NCT03479996
- Testing
- Marcaine 0.5 % Injectable Solution
- Where
- Israel
- Volunteers
- 22 people
- Sponsor
- Barzilai Medical Center
Rib Fractures
Rhomboid Intercostal Block Combined With Sub-Serratus Plane Block Versus Erector Spinae Plane Block
The aim of this study is to assess the quality of analgesic efficacy and improvement of pulmonary function in patients with fracture ribs receiving either continuous rhomboid intercostal block combined with sub-serratus block or…
- Trial name
- NCT05506761
- Testing
- ultrasound-guided erector spinae plane block, ultrasound-guided rhomboid intercostal block combined with sub-serratus plane block
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University
Pain, Postoperative, Serratus Anterior Plane Block
Comparison of Deep Serratus Anterior Plane Block and Combination of Deep and Superficial Serratus Anterior Plane Block
Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS.
- Conditions
- Pain, Postoperative, Serratus Anterior Plane Block, Multimodal Analgesia, Thoracic Surgery, Video-Assisted
- Trial name
- NCT05106283
- Testing
- Deep block and Combined Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Cardiac Output, Hypotension
Cardiac Output Changes During Hyperbaric and Isobaric Bupivacaine in Patients Undergoing Cesarean Section
Spinal block leads to the reduction of systemic vascular resistance (SVR) which may effect the cardiac output. Ngan Kee et al. has showed that spina block with 0.5% hyperbaric bupivacaine for Cesarean section combined with…
- Conditions
- Cardiac Output, Hypotension, Anesthesia, Spinal
- Trial name
- NCT02737813
- Testing
- Isobaric marcaine, Hyperbaric marcaine
- Where
- Thailand
- Volunteers
- 168 people
- Sponsor
- Mahidol University
Hemorrhoids, Anal Fissure and Fistula
Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia
Study Description: The goal of this clinical trial is to compare the duration of postoperative pain relief achieved with two different approaches to pudendal nerve block in patients undergoing elective perianal surgery.
- Conditions
- Hemorrhoids, Anal Fissure and Fistula, Perianal Abscess, Perianal Fistula
- Trial name
- NCT05990569
- Testing
- Ultrasound guided Pudendal nerve block
- Where
- Nepal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nepal Mediciti Hospital
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