Clinical trials: Caffeine
Athletic Performance, Dietary Supplement
The Effects of Acute Nitrate and Caffeine Co-ingestion on Discipline-Specific Exercise Performance.
The purpose of this study is to investigate the acute, separate, and combined ergogenic effects of dietary nitrate (beetroot juice, BJ) and caffeine (CAF) supplementation on discipline-specific athletic performance.
- Conditions
- Athletic Performance, Dietary Supplement, Iron Status
- Trial name
- NCT07748416
- Testing
- Caffeine, Dietary Nitrate (Beetroot Juice)
- Where
- Poland
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Community-acquired Pneumonia, Skin Infection
Improving Short Course Treatment for Common Pediatric Infections
Randomized quality improvement trial to improve the proportion of cases of community-acquired pneumonia (CAP) treated with no more than 5 days of antibiotics the proportion of cases of skin and soft tissue infections (SSTI)…
- Trial name
- NCT06087809
- Testing
- Education and feedback, Clinical decision support
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston Children's Hospital
Caffeine
Direct Effect of Caffeine on Diaphragmatic Muscles
The mechanism of methylxanthines is thought to increase chemoreceptor responsiveness to CO2 in central nervous system. Besides, effect of methylxanthines on diaphragmatic contractility has also been found in experimental studies.
- Trial name
- NCT04483492
- Testing
- Caffeine citrate
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Hacettepe University
HFrEF - Heart Failure With Reduced Ejection Fraction, HFmrEF
Coffee Use, Physical Activity and Symptomatic Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction and an ICD
The goal of this observational study is to learn whether caffeine consumption is associated with ventricular arrhythmias and physical activity in adults with heart failure, reduced left ventricular ejection fraction, and an…
- Conditions
- HFrEF - Heart Failure With Reduced Ejection Fraction, HFmrEF, Ventricular Arrhythmia, ICD
- Trial name
- CUPS-ICD (NCT07823998)
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 170 people
- Sponsor
- Jean-Benoît Le Polain de Waroux
Exercise Performance of Fit Athletes, Exercise Performance
Effect of the Combination of Nitrate and Caffeine on Critical Power In Trained Male Cyclists
This study is investigating the independent and combined effects of acute dietary nitrate and caffeine supplementation on performance during a 3-minute all-out cycling test in trained male cyclists.
- Conditions
- Exercise Performance of Fit Athletes, Exercise Performance, Cycling Performance
- Trial name
- BEET (NCT07501806)
- Testing
- Dietary Nitrate, Caffeine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Healthy Volunteers
A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)
The purpose of this healthy volunteers drug-drug interaction study is to assess the CYP1A2 and CYP3A4 perpetrator interaction potential and CYP1A2 victim potential of TEV-56286 (anle138b).
- Trial name
- NCT05532358
- Testing
- anle138b (TEV-56286), Fluvoxamine 100 mg QD for 5 days
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- MODAG GmbH
Depression, Depressive Disorder, Major
Sleep, Wake and Light Therapy for Depression
The aim of this study is to determine if altering the pattern of one's sleep and having light therapy can speed up the treatment of depression.
- Conditions
- Depression, Depressive Disorder, Major, Depression, Unipolar, Depression Moderate
- Trial name
- NCT03405493
- Testing
- Wake and Light Therapy, Sleep and Light Therapy
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College London
Gonorrhea, Neisseria Gonorrhea
Metagenomic Analysis of the Pharynx in High Risk Partners
The Neisseria gonorrhoea (NG) epidemic in England is at the highest level in one hundred years of public health records. The World Health Organisation has listed NG as one of the top five bacterial infections globally because of…
- Conditions
- Gonorrhea, Neisseria Gonorrhea, Neisseria Meningitidis, Metagenomic Next Generation Sequencing
- Trial name
- NCT07671014
- Volunteers
- 100 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Incontinence, Erectile Dysfunction Following Radical Prostatectomy
Additional Effects of Aerobic and Resistance Exercises to Pelvic Floor Muscle Training After Radical Prostatectomy
In the literature, studies about urinary symptoms after radical prostatectomy (RP) are generally focused on urinary incontinence (UI), and studies about sexual symptoms are focused on erectile dysfunction (ED).
- Trial name
- NCT06126874
- Testing
- Patient Education, Pelvic Floor Muscle Training, Aerobic Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Hacettepe University
Stress, Signs and Symptoms, Digestive
The Acute Effect of Coffee Consumption on Stomach, Self-reported Gastrointestinal Symptoms and Stress.
This study investigated the acute effect of the consumption of four different kinds of coffee (hot and cold instant coffee, cold espresso and hot filter coffee) with the same caffeine content on salivary gastrin, cortisol and…
- Conditions
- Stress, Signs and Symptoms, Digestive, Blood Pressure, Increased Secretion of Gastrin
- Trial name
- NCT02253628
- Testing
- Cold espresso, Hot instant coffee, Cold instant coffee
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Neck Pain, Neck Pain Musculoskeletal
Sleep Hygiene Plus Physiotherapy for Sleep and Disability in Chronic Neck Pain
This study investigates the effectiveness of a combined intervention that integrates sleep hygiene education with physiotherapy exercises in patients suffering from chronic neck pain.
- Conditions
- Neck Pain, Neck Pain Musculoskeletal, Sleep Disturbances, Fatigue, Mental
- Trial name
- NCT07178496
- Testing
- Sleep Hygiene Techniques, conventional physiotherapy program, Control arm
- Where
- Palestinian Territories
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Autonomic Nervous System, Cardiovascular Outcomes
Impact of Caffeine Intake on Autonomic Parameters in the Exercise of Strength
The objective of this study was to evaluate the variability of the heart rate of exercise physicists with and without caffeine intake.
- Trial name
- NCT03899675
- Testing
- Caffeine
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pernambuco
Irritable Bowel Syndrome
Effect of Neurodynamic Mobilization of Vagus Nerve on Irritable Bowel Syndrome in Women
goal of this interventional study to investigate the effect of neurodynamic mobilization of vagus nerve on irritable bowel syndrome in women.
- Trial name
- NCT07560345
- Testing
- neurodynamic mobilization of vagus nerve, Standard care
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Bronchopulmonary Dysplasia
Effect of Caffeine Versus Probiotic on Preterm Neonates With Bronchopulmonary Dysplasia
The aim of this study is to evaluate the effectiveness of caffeine versus probiotics supplementation as adjuvant therapy for preterm neonates with Bronchopulmonary dysplasia (BPD).
- Trial name
- NCT05682807
- Testing
- Caffeine, Probiotic Formula
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Coffee, Pregnancy
Coffee Consumption and Pregnancy
Coffee, tea, and cocoa contain caffeine, a plant alkaloid. They are frequently consumed during pregnancy. We examined the effect of coffee consumption on fetal renal artery blood flow and amniotic fluid index (AFI) in the third…
- Trial name
- NCT03798275
- Testing
- coffee
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Wrinkle, Spot Pigmented
Skin Rejuvenation With Topical Extract and Other Nutraceuticals
Hemp extract has been shown in several pre-clinical and clinical studies to have anti-aging effects on the skin through anti-oxidant and anti-inflammatory effects, in addition resveratrol, thyme and caffeine have been shown to…
- Conditions
- Wrinkle, Spot Pigmented, Lines Skin
- Trial name
- NCT05734703
- Testing
- Nutraceutical Topical
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical Life Care Planners, LLC
Caffeine, Placebo
Caffeinated Chewing Gum on Special Forces Performance
The purpose of this project is to investigate the effects of caffeine chewing gum on the cognitive functions and special operations capabilities of special forces.
- Trial name
- NCT06638372
- Testing
- caffeine
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Leukemia, Myeloid, Acute
A Study of Perpetrator Drug Interactions of Enasidenib in AML Patients
This is a 2-part, open-label, interventional study conducted in approximately 42 subjects with AML harboring an IDH2 mutation. The overall study is a 3-arm investigation of the PK effects of enasidenib at steady state on the…
- Trial name
- NCT03720366
- Testing
- enasidenib, Arm 1 probes, Arm 2 Probes
- Where
- 10 sites in Australia, South Korea
- Volunteers
- 40 people
- Sponsor
- Celgene
Hepatitis C
Study to Determine the Potential DDIs When the Daclatasvir/Asunaprevir/BMS-791325 Three Drug Antiviral Combination Tablet (FDC) is Coadministered With a Cocktail of Cytochrome P450 (CYP) Probe Substrates and Transporter Probe Substrates (Digoxin and Pravastatin) in Healthy Subjects
The primary purpose of this study is to assess the effect of the Daclatasvir/Asunaprevir/BMS-791325 fixed dose combination (FDC) tablet on the pharmacokinetics of the cocktail CYP and transporter probe substrates and to assess…
- Trial name
- NCT02045966
- Testing
- Cocktail, DCV 3DAA FDC, BMS-791325
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Renal Cell Carcinoma (RCC), Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
This is a multicenter Phase 1b, open label, dose-escalation and cohort-expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), preliminary antitumor activity, and effect of biomarkers of zanzalintinib…
- Conditions
- Renal Cell Carcinoma (RCC), Metastatic Castration-Resistant Prostate Cancer (mCRPC), Urothelial Carcinoma (UC), Solid Tumor
- Trial name
- STELLAR-002 (NCT05176483)
- Testing
- Zanzalintinib, Nivolumab, Ipilimumab
- Where
- 122 sites in United States, Australia and 11 more
- Volunteers
- 1,394 people
- Sponsor
- Exelixis
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