Clinical trials: Caffeine
Migraine With Aura, Migraine Without Aura
Maxalt 10mg Plus Caffeine 75mg in the Acute Treatment of Migraine Headache
The purpose of this study is to evaluate the effect of rizatriptan, alone or combined with caffeine for treating acute attacks of migraine. Each subject will have 3 months to treat 3 acute migraine headache attacks.
- Trial name
- NCT00471952
- Testing
- Maxalt 10mg MLT plus Caffeine 75mg
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Diamond Headache Clinic
Healthy Volunteers
Food Effect and CYP1A2 Induction Study in Healthy Subjects
This study will evaluate the effect of food and smoking on healthy older subjects taking pomalidomide.
- Trial name
- NCT02168205
- Testing
- Pomalidomide, Caffeine, Tobacco
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Celgene
Stress Urinary Incontinence in Women
Comparison of Two Over the Counter Intravaginal Devices for the Treatment of Stress Urinary Incontinence
The goal of this pilot study is to compare two commercially available over the counter devices for treatment of stress urinary incontinence in a web based format. The main questions it aims to answer 1.
- Trial name
- IMPRIVE (NCT06698627)
- Testing
- Daily Disposable Continence Device, Monthly Disposable Continence Device
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University Medical Center
Coronary Artery Disease
Does Caffeine Affect the Sensitivity of Adenosine Perfusion Scans?
We are studying the affect of caffeine on the sensitivity of detecting coronary artery disease (blockages in the blood flow to the heart) with adenosine tracer scans.
- Trial name
- NCT00205166
- Testing
- Cardiac SPECT imaging Rest and Stress, Caffeine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Hepatitis C
Study to Determine the Potential DDIs When the Daclatasvir/Asunaprevir/BMS-791325 Three Drug Antiviral Combination Tablet (FDC) is Coadministered With a Cocktail of Cytochrome P450 (CYP) Probe Substrates and Transporter Probe Substrates (Digoxin and Pravastatin) in Healthy Subjects
The primary purpose of this study is to assess the effect of the Daclatasvir/Asunaprevir/BMS-791325 fixed dose combination (FDC) tablet on the pharmacokinetics of the cocktail CYP and transporter probe substrates and to assess…
- Trial name
- NCT02045966
- Testing
- Cocktail, DCV 3DAA FDC, BMS-791325
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Analgesia, Caffeine
Caffeine Intake Inrelation to Perioperative Analgesic Consumption
Caffeine is the most widely consumed psychoactive drug in the world. Natural sources of caffeine include coffee, tea, and chocolate.
- Trial name
- NCT05330754
- Testing
- Caffeine intake in mg
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Acute Coronary Syndrome
AngelMed Guardian® System PMA Post Approval Study
500 Patients (minimum) will be enrolled following commercial implant. Will be treated by their physicians using the standard of care.
- Trial name
- NCT05412927
- Testing
- PMA P150009 AngelMed Guardian® System
- Where
- 18 sites in United States
- Volunteers
- 500 people
- Sponsor
- Angel Medical Systems
Heart Rate Fast, Blood Pressure
Short-term Effects of Passiflora and Meditation on Blood Pressure and Heart Rate
This study is intended to study the effects of one-time acute dosing of a solid extract of Passiflora incarnata, also known as Passionflower, on blood pressure and heart rate in students.
- Trial name
- NCT03953469
- Testing
- Passiflora incarnata
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Bridgeport
Healthy
Caffeine Intake and Additive Effects on Cognition
Caffeine is a methylxanthine commonly consumed by the population for their psychostimulant properties, and their intake when in moderate doses seem to produce positive effects on stress, mood and memory.
- Trial name
- Caffeine (NCT02647567)
- Testing
- Caffeine Intake
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Dietary Modification
Assessment of a Pre-Workout Dietary Supplement
The purpose of this study is to examine the acute effects of a pre-workout dietary supplement on energy metabolism, cardiovascular hemodynamics, blood metabolites and mental focus.
- Trial name
- NB1 (NCT02952014)
- Testing
- C4 Extreme, C4 Extreme (without Advantra Z
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Overactive Bladder, Caffeine
"The Effects of Caffeine on Overactive Bladder Symptoms and Mental Health in Postmenopausal Women"
The purpose of this study is to observe effects of caffeine on overactive bladder symptoms and wellbeing. This study looks at whether caffeine has bad effects on urinary symptoms or if lower doses of caffeine decrease the…
- Conditions
- Overactive Bladder, Caffeine, Menopause
- Trial name
- NCT02180048
- Testing
- 400 mg of caffeine/day (Two 200mg pills/day)
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Caffeine
The Repeatability of the Effect of Caffeine Supplementation on Submaximal Physiological Responses and Cycling Time Trial Performance
Recently, Grgic (2018) discussed the concept of responders and non-responders to caffeine supplementation highlighting the importance of the repeatability of results.
- Trial name
- NCT06935214
- Testing
- Caffeine
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Healthy
Effects of a Multi-Ingredient Pre-Workout Supplement on Energy Expenditure During Running
The primary purpose of this study was to examine the acute effects of one versus two doses of a multi-ingredient pre-workout supplement on energy expenditure during moderate-intensity treadmill running.
- Trial name
- NCT04352998
- Testing
- One dose pre-workout condition, Two dose pre-workout condition
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northern Illinois University
Dyspepsia, Functional Gastrointestinal Disorders
Traditional Dietary Advice Versus Low FODMAP Diet in Postprandial Functional Dyspepsia
Functional dyspepsia is common, affecting 7.2% of the global population, and associated with substantial health impairment. Almost 80% of patients with functional dyspepsia report meal-related symptoms and are classified as…
- Trial name
- NCT05810168
- Testing
- Dietary modifications
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Healthy, Caffeine
Effects of Caffeinated Beverages on Well-being
This study will evaluate post-beverage subjective caffeine responses and physiological responses to caffeinated beverages in generally healthy adults.
- Conditions
- Healthy, Caffeine, Beverage Intake
- Trial name
- NCT07357818
- Testing
- Participants' typical caffeinated beverage, Test caffeinated beverage
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- GUAYAKI SUSTAINABLE RAINFOREST PRODUCTS, INC.
Drug Drug Interaction (DDI)
A Study Evaluating the Potential of BMS-984923 to Alter the Systemic Exposure of Three Orally Administered Probe Substrates
The goal of this study is to learn if the investigational drug, BMS-984923 will impact the exposure and clearance of other medications when given together.
- Trial name
- NCT06632990
- Testing
- BMS-984923, Midazolam, Caffeine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Allyx Therapeutics
Depressive Disorder
Bupropion & Cardio Birth Defect (Slone)
Bupropion is a unique drug that is used both to treat depression and as an aid in smoking cessation. In 2008, the final report from the Bupropion pregnancy registry described 24 congenital malformations among the 675 women…
- Trial name
- NCT01597661
- Testing
- Exposure to any bupropion during the first trimester, Exposure to bupropion alone during the first trimester, Referent group: no exposure to any anti-depressant or anti-smoking drug during pregnancy
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Metabolism
A Study to Examine the Effect of a Thermogenic Energy Drink in Healthy Adults
This study is intended to examine the acute thermogenic effects of the active study product (energy drink), in healthy adults.
- Trial name
- NCT05061797
- Testing
- Thermogenic Energy Drink - Active Study Product Formula
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rowdy Energy
Healthy Adult Participants
A Multiple-dose Study Investigating the Drug-drug Interaction Potential and QTc Effects of Fosmanogepix in Healthy Adult Subjects
This is a Phase 1, fixed-sequence, multiple-dose study in approximately 42 healthy adult participants. The study will be conducted in two parts.
- Trial name
- NCT07881224
- Testing
- Fosmanogepix, The medicine cocktail (caffeine, bupropion, flurbiprofen, omeprazole, dextromethorphan and midazolam), Probe substrates (repaglinide, rosuvastatin, and digoxin)
- Where
- Netherlands
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Basilea Pharmaceutica
Hyperthermia
Military Alerting System for Monitoring Body Temperature During Active Cooling
BHSAI is developing a computational system that provides early alerts of a rise in core body temperature to help reduce the risk of heat injury in the field and during training.
- Trial name
- MAMBA (NCT04431596)
- Testing
- Forearm cooling, Mist-fan cooling
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
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