Clinical trials: Caffeine, completed
Anesthesia
Postdural Puncture Headache Relief With Aminophylline and SPGB
The purpose of the study is to compare Sphenopalatine ganglion block (SPGB) and aminophylline in the efficacy and safety management of PDPH.
- Trial name
- NCT05552404
- Testing
- conservative therapy, Aminophylline, trans nasal sphenopalatine ganglion block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Health
Acute Effects of Coffee on Appetite and Inflammation Markers, Glucose Metabolism and Energy Intake
The purpose of the study is to investigate whether caffeinated and decaffeinated coffee consumption has acute effects on subjective appetite feelings, energy intake and biochemical markers related to appetite, inflammation and…
- Trial name
- NCT01174576
- Testing
- caffeinated and decaffeinated coffee
- Where
- Greece
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Healthy Adults
Ketone Production With Acute Caffeine Intake
Evaluate the effect of a caffeine supplement on the stimulation of lipolysis and the production of ketones in healthy adults (N=10).
- Trial name
- NCT02694601
- Testing
- Control, Caffeine low dose, Caffeine high dose
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Diabetes Mellitus, Type 2
Experimental Studies of the Effects of Caffeine on Glucose Regulation
This project contains experimental studies of the effects of the drug caffeine on glucose regulation in adults who have Type 2 diabetes.
- Trial name
- NCT00432887
- Testing
- caffeine administration
- Volunteers
- 150 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Post-traumatic Stress Disorder
Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance
The purpose of this study is to compare the effectiveness of two cognitive behavioral group psychotherapy interventions in controlling the subjective sleep disturbance in veterans with Post-traumatic Stress Disorder.
- Trial name
- NCT00108628
- Testing
- Imagery Rehearsal, Sleep and Nightmare Management
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- US Department of Veterans Affairs
Caffine, Placebo - Control
Effects of Caffeine Ingestion on Morning Cognitive and Muscle Strength Measures in Males
Tournament scheduling and environmental factors often require athletes to compete in the morning. Equally due to time constraints, athletes may choose to train in the morning.
- Conditions
- Caffine, Placebo - Control, No Pill
- Trial name
- NCT07466628
- Testing
- No Pill
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Insomnia
Effectiveness of a Guided Self-help Intervention for Improving Sleep in University Students
This randomized controlled trials aims to assess the effectiveness of an online guided self-help intervention ('i-Sleep \& BioClock') based on CBTi principles for university students' sleep problems.
- Trial name
- NCT06023693
- Testing
- i-Sleep & BioClock, Online Psychoeducation
- Where
- Netherlands
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Spinal Cord Injuries
Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with…
- Trial name
- NCT02323698
- Testing
- Caffeine, AIH
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Apnea of Prematurity, Caffeine
Target Weaning Oxygen to Determine Cafffeine Duration for AOP
Caffeine, a typical representative of methylxanthine, is world-widely used to manage apnea of prematurity (AOP) in neonatology. However, an appropriate medication regimen of caffeine has not been well defined until now.
- Conditions
- Apnea of Prematurity, Caffeine, Weaning Oxygen, Medicine Regimen
- Trial name
- DCAP (NCT04868565)
- Testing
- Caffeine Citrate 20 MG/1 ML Intravenous Solution [CAFCIT]
- Where
- 41 sites in China
- Volunteers
- 310 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Cardiovascular System
Effects of Caffeine on Cerebral Blood Flow
The goal of this clinical trial is to evaluate in clinically healthy young people if: after caffeine ingestion, there are variations in blood velocity of the middle cerebral arteries (VMCA), this variation is dependent on the…
- Trial name
- NCT05866848
- Testing
- Anhydrous caffeine (45mg), Anhydrous caffeine (120mg)
- Where
- Portugal
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde de Coimbra
Atrial Fibrillation
Prevention of Atrial Fibrillation Following Valvular Replacement With Cardiopulmonary Bypass: a Prospective, Randomized Clinical Study Comparing Oral Caffeine With Placebo
Atrial fibrillation remains a major cause of morbidity following cardiac surgery with cardiopulmonary bypass. Many mechanisms have been implicated.
- Trial name
- NCT01999829
- Testing
- citrate of caffeine
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Musculoskeletal Pain
Efficacy and Safety of the Combination of Ketoprofen and Cyclobenzaprine and Caffeine in Osteomuscular Treatment
The purpose of this study is to evaluate the safety and efficacy of an association with one anti-inflammatory and one muscle relaxant plus caffeine compared to one anti-inflammatory plus caffeine in the treatment of osteomuscular…
- Trial name
- NCT02862977
- Testing
- ketoprofen and cyclobenzaprine association with caffeine, Cyclobenzaprine with caffeine
- Where
- 6 sites in Brazil
- Volunteers
- 414 people
- Sponsor
- EMS
Type 1 Diabetes
Effects of Acute Intake of Caffeinated Beverages in Type 1 Diabetes
The aim of this pilot study is to determine the impact of caffeine-enhanced energy drinks on blood glucose excursion on heart rate, blood pressure, cardiac output and cognitive performance in patients with type 1 diabetes.
- Trial name
- REDBULL (NCT01805700)
- Testing
- Caffeine enhanced energy drink, Glucose drink
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- The Royal Bournemouth Hospital
Caffeine Use Disorder (DSM-5 Condition for Further Study)
Treatment for Caffeine Dependence
Recent research has shown that some individuals become addicted to or dependent on caffeine and are unable to quit or reduce caffeine consumption despite a persistent desire to do so.
- Trial name
- NCT01951872
- Testing
- Manual-based treatment for caffeine dependence
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Johns Hopkins University
COPD
Long-term Activity Coaching in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of mortality and morbidity around the world. Studies revealed that patients with COPD are less active than age-matched healthy controls and activity level decreases…
- Trial name
- NCT04139200
- Testing
- Type 1 physical activity tele coaching intervention, Type 2 physical activity tele coaching intervention
- Where
- 2 sites in Belgium
- Volunteers
- 150 people
- Sponsor
- KU Leuven
Erectile Dysfunction
Research Evaluating an Investigational Medication for Erectile Dysfunction - Diabetic ED (REVIVE-D)
This study is being conducted to compare the safety and efficacy of 2 doses of avanafil to placebo in diabetic men with mild to severe erectile dysfunction.
- Trial name
- REVIVE-D (NCT00809471)
- Testing
- avanafil
- Where
- 39 sites in United States
- Volunteers
- 390 people
- Sponsor
- VIVUS LLC
Acne Vulgaris
Reduced Side-Effects of Photodynamic Therapy for the Treatment of Moderate to Severe Acne (i-PDT)
This research study aims to compare different methods for helping difficult to treat or scarring (cystic) acne, ALA-PDT and i-PDT.
- Trial name
- i-PDT (NCT01689935)
- Testing
- 20 % Aminolevulinic Acid, Red light only, Blue light only
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Parkinson's Disease
Caffeine for Motor Manifestations of Parkinson's Disease
Numerous epidemiological studies have linked lifelong use of caffeine to a lower risk of Parkinson's disease (PD) - prospective studies have estimated that non-coffee drinkers have an approximately 1.7-2.5 fold increased risk of…
- Trial name
- NCT01190735
- Testing
- Caffeine alkaloid
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Ron Postuma
Hand Washing, Handwashing
The Effect of Behaviour Change Interventions on Use of Public Handwashing Stations in Bangladesh
As part of the COVID-19 response, BRAC has built 1000 public handwashing stations in several hundred villages in 20 sub-districts of Bangladesh.
- Conditions
- Hand Washing, Handwashing, Covid19
- Trial name
- NCT04765540
- Testing
- Low Intensity Nudges, High Intensity Activities, BRAC's business-as-usual
- Where
- 3 sites in Bangladesh
- Volunteers
- 855 people, healthy volunteers welcome
- Sponsor
- The Behavioural Insights Team
Obesity
"Pecos" B-adrenergic and PPAR-G Stimulation Upregulates Lipid Metabolism in Human Subcutaneous Fat
This study compares four treatments to see which one causes the most weight loss, fat loss, loss of abdominal fat and improvement in blood tests like cholesterol.
- Trial name
- NCT00377975
- Testing
- Ephedrine, Pioglitazone, Caffeine
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center