Clinical trials: Caffeine
Health Behavior
The Effects of a Personalized Sleep Improvement App From SleepScore Labs
The study is a single-blinded randomized waitlist controlled trial that aims to assess changes in objective and self-report sleep improvement through use of a dynamic and personalized sleep improvement smartphone app and advice…
- Trial name
- NCT05195359
- Testing
- Dein Schlaf. Dein Tag. sleep improvement application powered by SleepScore
- Where
- Germany
- Volunteers
- 637 people, healthy volunteers welcome
- Sponsor
- ResMed
Abdominoplasty, Diaphragm
Gastroesophageal Reflux and Respiratory Function in Patients Undergoing Abdominoplasty
The objective of this observational study is to compare parameters of diaphragmatic mechanics, respiratory muscle function, and thoracoabdominal kinematics among women with gastroesophageal reflux disease (GERD) and a history of…
- Conditions
- Abdominoplasty, Diaphragm, Respiratory Mechanics, Gastroesophageal Reflux Disease
- Trial name
- NCT07868562
- Testing
- Assessment of anthropometric and sociodemographic data and clinical history, Assessment of Symptoms, Quality of Life, and Physical Activity, Spirometric assessment
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Physiological Stress
Impact of Supplements on Stress Markers
The goal of this clinical trial is to examine the effects of caffeine, theanine and tyrosine ingestion on markers of stress in healthy college aged individuals that are exposed to a mental stress task.
- Trial name
- NCT05592561
- Testing
- mental stress task
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Texas State University
Bronchopulmonary Dysplasia
Effect of Caffeine Versus Probiotic on Preterm Neonates With Bronchopulmonary Dysplasia
The aim of this study is to evaluate the effectiveness of caffeine versus probiotics supplementation as adjuvant therapy for preterm neonates with Bronchopulmonary dysplasia (BPD).
- Trial name
- NCT05682807
- Testing
- Caffeine, Probiotic Formula
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Acute Kidney Injury
Multi-hospital Electronic Decision Support for Drug-associated Acute Kidney Injury
This study is a randomized controlled trial at eight hospitals within the University of Pittsburgh Medical Center-UPMC system. The project will assess the efficacy of a clinical surveillance system augmented with near real-time…
- Trial name
- MEnD-AKI (NCT06264752)
- Testing
- Level A, Level B, Passive Alert
- Where
- 8 sites in United States
- Volunteers
- 698 people
- Sponsor
- University of Pittsburgh
Heart Failure
Innovative Care of Older Adults With Chronic Heart Failure: A Comparative Effectiveness Clinical Trial (I-COACH)
An estimated 6.5 million adults in the U.S. have Heart Failure (HF) and the prevalence is increasing. HF is characterized by poor quality of life but this is amenable to self-management.
- Trial name
- I-COACH (NCT04304833)
- Testing
- Provider-Based Care Model Arm, mHealth Model Arm
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Arkansas
Quality of Work Life, Burn-out
Effect of in Situ Simulation on Quality of Work Life and Multiprofessional Team Effectiveness in the Intensive Care Unit
The lack of specific, personalized training for intensive care workers can lead to a deterioration in quality of life at work, and can result in burnout, absenteeism or wanting to leave the service.
- Conditions
- Quality of Work Life, Burn-out, Simulation
- Trial name
- EFFIQUASS (NCT06944821)
- Testing
- In-situ simulation, Role-playing using a simulation scenario, Questionnaires
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Caffeine; Sleep Disorder
Influence of Caffeine Therapy in Preterm Infants
The development of sleep wake cycles is indicative of child's neurocognitive functions. Caffeine therapy is commonly used in neonatal intensive care units for treatment of apnea of prematurity (AOP), to reduce mechanical…
- Trial name
- NCT04376749
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Healthy
Effects of Modafinil, Caffeine and Methylphenidate in Healthy Volunteers
In this study the investigators compare three stimulants to each other. The effects of these agents on cognitive performance (eg, attention and memory) and on the brain are being measured.
- Trial name
- MKM (NCT02071615)
- Testing
- Methylphenidate 20 mg tablet given once by mouth, modafinil 200mg tablet given once by mouth, caffein 200mg tablet given once by mouth
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Polycystic Ovary Syndrome
Effect of Laser Acupuncture on Insulin Resistance in Obese Women With Polycystic Ovarian Syndrome
This study will be conducted to investigate the effect of laser acupuncture on insulin resistance in obese women with polycystic ovarian syndrome.
- Trial name
- NCT06549647
- Testing
- low caloric diet, Laser Acupuncture
- Volunteers
- 40 people
- Sponsor
- Cairo University
Headache, Pregnancy Related
Acute Headache Treatment in Pregnancy: Occipital Nerve Block vs PO Acetaminophen With Caffeine
This is an open label randomized controlled trial evaluating response to bupivacaine occipital nerve block compared to Tylenol/Caffeine cocktail in treatment of pregnant patients seeking care of headache.
- Conditions
- Headache, Pregnancy Related, Occipital Nerve Block
- Trial name
- NCT03951649
- Testing
- Occipital Nerve Block
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Body Weight
Effect of Coffee and Tea Consumption on Adolescent Weight Control
Introduction: The influence of tea or coffee supplementation on body weight in adolescents has never been tested. The aim of the present study was to investigate the effect of tea and coffee consumption on body weight and body…
- Trial name
- NCT05181176
- Testing
- Coffee, Green tea
- Where
- Israel
- Volunteers
- 63 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Dietary Supplements
Safety of a Ready to Drink Supplement
This study will examine a Ready to Drink (RTD) supplement.
- Trial name
- NB10 (NCT03032549)
- Testing
- RTD
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Pain, Postoperative, Surgery--Complications
Celecoxib vs. Acetaminophen/Codeine/Caffeine for Post-operative Analgesia in Rhinoplasty.
The primary aim of this study is to evaluate whether celecoxib (CELEBREX) is equivalent to acetaminophen-codeine-caffeine (TYLENOL# 3) for the management of pain after primary elective open septorhinoplasty with osteotomies.
- Conditions
- Pain, Postoperative, Surgery--Complications, Opioid Analgesic Adverse Reaction, Opioid Use
- Trial name
- NCT04259333
- Testing
- Celecoxib 200mg, Acetaminophen, Codeine Drug Combination
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Blake Raggio
Headache, Tension-Type
A Pharmacokinetic Study of an Experimental Paracetamol Formulation
This PK study is designed to show bioequivalence between the study treatments.
- Trial name
- NCT01476176
- Testing
- Experimental paracetamol, Paracetamol marketed formulation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Medication Overuse Headache
Medication Overuse Headache (MOH) and an Innovative Approach
Appropriate delivery of quality healthcare requires constant monitoring of the patient during follow up, particularly in the presence of chronic diseases.
- Trial name
- COMOESTAS (NCT02435056)
- Testing
- IEPR Approach
- Volunteers
- 690 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
HIV/AIDS and Infections, Electronic Medical Records
Evaluation of Clinical Impacts and Costs of eHealth in Rwanda
This study will estimate the impact of a suite of clinical decision-support tools on structural, process, and clinical outcomes related to HIV care.
- Conditions
- HIV/AIDS and Infections, Electronic Medical Records, Clinical Decision Support System
- Trial name
- NCT04283929
- Testing
- Experimental: Intervention 1 (Int1), Experimental: Intervention 2 (Int2), Experimental: Intervention 3 (Int3)
- Where
- Rwanda
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National University, Rwanda
Advanced Solid Tumors, Metastatic Melanoma
Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors
This is an open-label, 3-arm, fixed-sequence study to evaluate the effect of single and multiple oral doses of encorafenib in combination with binimetinib on the single oral dose pharmacokinetics (PK) of cytochrome P450 (CYP)…
- Trial name
- NCT03864042
- Testing
- losartan, dextromethorphan, caffeine
- Where
- 29 sites in United States, Belgium and 3 more
- Volunteers
- 56 people
- Sponsor
- Pfizer
Autism, Autism Spectrum Disorder
A Behavioral Intervention for Ameliorating Sleep Problems in Children With ASD
The present study will test the effectiveness of a behavioral intervention program that targets sleep problems in 1.5-5-year-old children with ASD.
- Conditions
- Autism, Autism Spectrum Disorder, Sleep
- Trial name
- NCT04539990
- Testing
- Behavioral treatment for sleep difficulties
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Whiplash
Chronic Whiplash Associated Disorders: Disability, Pain (Beliefs), Central Sensitization and Brain Activity
This is a cross-sectional case-control study in which 70 patients with chronic whiplash associated disorders will be recruited and compared to 70 healthy pain-free controls.
- Trial name
- NCT04204525
- Testing
- Quantitative sensory testing
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- University Ghent
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