Clinical trials: Caffeine, completed
Acute Kidney Injury
An Electronic Alert System for In-Hospital Acute Kidney Injury
This study will randomize hospitalized patients with acute kidney injury (AKI) to usual care, or an electronic alert intervention.
- Trial name
- NCT01862419
- Testing
- Alert
- Where
- United States
- Volunteers
- 2,393 people
- Sponsor
- University of Pennsylvania
Healthy Volunteers
Testing Potential Synergistic Effects of Albuterol and Caffeine on Metabolic Rate
The purpose of this study is to define a ratio of Caffeine and albuterol that gives a synergistic increase in metabolic rate.
- Trial name
- CALM (NCT02135965)
- Testing
- 2mg of Albuterol, 4mg of Albuterol, 100mg of Caffeine
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
High Myopia, Choroid
Effect of Caffeine on Ocular Circulation in High Myopes
To investigate the effect of caffeine on ocular circulation by using Optical Coherence Tomography and Optical Coherence Tomography Angiography.
- Trial name
- NCT03294967
- Testing
- Caffeine, Vitamin E
- Where
- Hong Kong
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Healthy Adult Male
Effects of Caffeine on Agility in Amateur Soccer Players
This randomized, double-blind, placebo-controlled crossover clinical trial aims to investigate the acute effects of caffeine supplementation on motor and perceptual-cognitive components of agility performance in male amateur…
- Trial name
- NCT07844122
- Testing
- Caffeine 300 MG
- Where
- Slovakia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Comenius University
Complication,Postoperative
Continuous Wireless Monitoring of Vital Signs and Automated Alerts of Postsurgical Patient Deterioration.
The primary aim of the current study is to assess the effect of continuous wireless vital sign monitoring with generation of real-time alerts, compared to blinded monitoring without alerts on the cumulative duration of any…
- Trial name
- WARD-RCT-SX (NCT04640415)
- Testing
- Active Alarms
- Where
- 2 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Healthy
Salivary Proteome and Sensitivity to Bitterness
This study aims to establish whether the protein composition of healthy males contribute to their sensitivity to the bitterness of caffeine.
- Trial name
- PROTAMER (NCT01079338)
- Testing
- caffeine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Advanced Chronic Liver Disease, Healthy Participants
A Study to Investigate How Multiple Oral Doses of AZD2389 Affect the Pharmacokinetics of Midazolam, Caffeine, and Bupropion in Healthy Participants
The purpose of this study is to measure the effect of multiple doses of AZD2389 on the pharmacokinetics (PK) of midazolam, caffeine, and bupropion in healthy participants.
- Trial name
- CRIOLLO (NCT06973005)
- Testing
- AZD2389, Midazolam, Caffeine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Placebo Effect
The Effect of Tablet Size on Cognitive Performance Caffeine
This study aims to assess if tablet size, due to placebo effect, alters participants' performance on cognitive tests after consuming caffeine.
- Trial name
- CaC (NCT03694886)
- Testing
- Caffeine Anhydrous with small sucrose pill, Caffeine Anhydrous with large sucrose pill
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Colon Cancer
Chemopreventive Effects of Epigallocatechin Gallate (EGCG) in Colorectal Cancer (CRC) Patients
This will be a randomized, controlled pilot trial of patients with histological documentation of primary colon or rectal adenocarcinoma with resectable cancer, who have not received any treatments for cancer.
- Trial name
- NCT02891538
- Testing
- Epigallocatechin gallate (EGCG)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Preterm, Apnea of Prematurity
Caffeine Citrate Use and Electronic Activity of the Diaphragm (EDI) Changes
Caffeine citrate, the first-line agent for apnea of prematurity, enhances diaphragmatic activity. EDI values of neurally adjusted ventilatory assist (NAVA) modes can be used to quantify the diaphragmatic activity triggered by…
- Conditions
- Preterm, Apnea of Prematurity, Caffeine
- Trial name
- NCT05393817
- Testing
- caffeine citrate
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Seoul St. Mary's Hospital
Atrial Fibrillation
Automated Physician Notifications to Improve Guideline-Based Anticoagulation in Atrial Fibrillation
The overall goal is to improve outcomes among patients with atrial fibrillation (AF) by preventing stroke. The investigators propose to implement an automated algorithm using electronic medical record (EMR) data to alert…
- Trial name
- NCT02950285
- Testing
- Baseline alert
- Where
- United States
- Volunteers
- 2,336 people
- Sponsor
- Massachusetts General Hospital
Prostate Cancer, Prostate Adenocarcinoma
A Behavioral Health Intervention Using Digital Technology in Radiation Therapy for Prostate Cancer Patients
The purpose of this study is to determine how to incorporate a smart water bottle to improve bladder filling for prostate cancer patients undergoing radiation therapy.
- Conditions
- Prostate Cancer, Prostate Adenocarcinoma, Radiation Toxicity
- Trial name
- HIDRATEPRO (NCT04946214)
- Testing
- Smart Water Bottle
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Cardiovascular System
Effects of Caffeine on Cerebral Blood Flow
The goal of this clinical trial is to evaluate in clinically healthy young people if: after caffeine ingestion, there are variations in blood velocity of the middle cerebral arteries (VMCA), this variation is dependent on the…
- Trial name
- NCT05866848
- Testing
- Anhydrous caffeine (45mg), Anhydrous caffeine (120mg)
- Where
- Portugal
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde de Coimbra
Breast Cancer
Disposition of Dietary Polyphenols and Methylxanthines in Mammary Tissues From Breast Cancer Patients
The aim is to characterise the metabolic profiling of dietary polyphenols in normal and malignant breast tissues from breast cancer patients.
- Trial name
- POLYSEN (NCT03482401)
- Testing
- Polyphenol
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- National Research Council, Spain
Brown Adipose Tissue (BAT) Physiology, Cold Exposure
Effect of Caffeine on Cold-stimulated Brown Adipose Tissue Activity
The purpose of the study is to asses brown adipose tissue activity after a cold mild stimulus, preceded by 200mg caffeine or placebo administration.
- Trial name
- ACROBAT (NCT06978777)
- Testing
- Caffeine (200 mg)
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Meniere Disease, Psychosocial Problem
Comprehensive Evaluation in Patients With Meniere's Disease
The aim of our study is to determine the severity of the disease in people with Meniere's Disease; physical conditions such as balance, posture, pain, physical activity level, neck joint range of motion, proprioception; to…
- Conditions
- Meniere Disease, Psychosocial Problem, Physical Disability, Quality of Life
- Trial name
- NCT05844657
- Testing
- Case report form, Tinnitus disability scale, A feeling of fullness and/or pressure in the ear
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Parkinson Disease
DB RCT for Specialized Phototherapy in Parkinson's Disease.
This is a pivotal study to determine whether light therapy can improve non-motor and motor function in Parkinson's disease, on top of current best medical treatment.
- Trial name
- LIGHT-PD (NCT04453033)
- Testing
- Celeste Specialized Phototherapy Device
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- PhotoPharmics, Inc.
Satiety in Healthy Volunteers
Assessment of Satiety Following Oral Administration of an Erythritol Sweetened Beverage
Erythritol is a low calorie sugar substitute that is being increasingly used to sweeten beverages and other food items. Greater amounts of erythritol are required to reach the sweetness level of a common soft drink as compared to…
- Trial name
- NCT02934321
- Testing
- Erythritol, Aspartame
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Florida
Autonomic Nervous System, Cardiovascular Outcomes
Impact of Caffeine Intake on Autonomic Parameters in the Exercise of Strength
The objective of this study was to evaluate the variability of the heart rate of exercise physicists with and without caffeine intake.
- Trial name
- NCT03899675
- Testing
- Caffeine
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pernambuco
Fatigue, Mental, Alertness
Effect of Coffeeberry on Mood, Motivation and Cognitive Performance
The primary purpose is to test the short-term effects of the acute consumption of two novel beverages made from coffeeberries, the fruit of the coffee plant (Coffea arabica) benchmarked against caffeine on several aspects of…
- Conditions
- Fatigue, Mental, Alertness, Mood, Motivation
- Trial name
- NCT04974606
- Testing
- Cherry-flavored still beverage
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D