Clinical trials: Caffeine, completed
Alcohol Use Disorder
Preliminary Effectiveness of Remotely Monitored Blood Alcohol Concentration Device as Treatment Modality
State the scientific aim(s) of the study, or the hypotheses to be tested. The purpose of the current study is to evaluate the usage and acceptability of the Soberlink's blood alcohol concentration (BAC) unit in collaboration with…
- Trial name
- Soberlink (NCT04380116)
- Testing
- Soberlink
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Yale University
COVID-19
Drug-Drug Interaction Study Between EDP-235, Midazolam, Caffeine and Rosuvastatin in Healthy Subjects
A Drug-Drug Interaction study to assess the effects of EDP-235 on the Pharmacokinetics and Safety of midazolam, caffeine and rosuvastatin.
- Trial name
- NCT05594615
- Testing
- EDP-235, Midazolam, Rosuvastatin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Enanta Pharmaceuticals, Inc
Cardiovascular Disease, Acute Coronary Syndrome
Hybrid Effectiveness-Implementation Study to Improve Clopidogrel Adherence
Percutaneous coronary intervention (PCI) is a common invasive cardiovascular procedure performed in the VA with over 13,000 procedures in FY10.
- Trial name
- NCT01609842
- Testing
- Multifaceted Intervention with pharmacist and IVR
- Where
- 15 sites in United States
- Volunteers
- 14,573 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Dyskinesias
Pilot Study on Caffeine Efficiency in ADCY5-related Dyskinesia
Heterozygous mutations in the ADCY5 gene cause involuntary early-onset hyperkinetic movements. In addition, patients may have associated psychiatric disorders.There is currently no treatment.
- Trial name
- CAF-ADCY5 (NCT04351360)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Dysmenorrhea, Pelvic Pain
The Effect of Connective Tissue Massage in Women With Primary Dysmenorrhoea
The aim of this study is to investigate the effect of connective tissue manipulation on pain threshold in women with primary dysmenorrhoea. According to literature, there are studies that measure the pain threshold.
- Trial name
- NCT02372123
- Testing
- lifestyle advice, connective tissue manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Chronic HCV-related Hepatitis
Coffee Effect in HCV-related Hepatitis
Background: In patients with chronic HCV-related liver damage, coffee is associated with a reduced risk of progression and of hepatocellular carcinoma (HCC) development.
- Trial name
- NCT01572103
- Testing
- Coffee, coffee abstinence
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliera di Padova
Long COVID-19 Syndrome, Chronic Fatigue Syndrome
A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial
IRB approval date 14-APR-2024 and public at https://plataformabrasil.saude.gov.br/login.jsf since IURB approval Long COVID is a multi-systemic condition comprising often severe and persistent symptoms (longer than 12 weeks) that…
- Trial name
- REVIVE (NCT06128967)
- Testing
- Fluvoxamine Maleate 100 MG, Metformin Extended Release Oral Tablet
- Where
- 6 sites in Brazil
- Volunteers
- 399 people
- Sponsor
- Cardresearch
Energy Expenditure
Efficacy of ONE A DAY Weightsmart Advanced Versus Caffeine and Placebo on Energy Expenditure, Thermogenesis and Perceived Energy Levels in Women.
The study is considered research because efficacy (how well a drug works) information is needed in healthy, 25-45 year-old, female subjects with moderate caffeine intake.
- Trial name
- NCT00781586
- Testing
- One-A-Day Weight S.A. (Multi-Vitamins, BAY94-9350), Caffeine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Bayer
Postoperative Ileus, Cesarean Section Complications
The Effect of Caffeine Ingestion in Prevention of Postoperative Ileus After Caesarean Section.
Many trials have been made to prevent paralytic ileus , including administration of prokinetic drugs , early resumption of feeding, gum chewing and adequate pain control.
- Conditions
- Postoperative Ileus, Cesarean Section Complications, Caffeine
- Trial name
- NCT03815877
- Testing
- Nescafe Gold ® coffee, Nescafe Gold DECAF® coffee
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Community-acquired Pneumonia, Skin Infection
Improving Short Course Treatment for Common Pediatric Infections
Randomized quality improvement trial to improve the proportion of cases of community-acquired pneumonia (CAP) treated with no more than 5 days of antibiotics the proportion of cases of skin and soft tissue infections (SSTI)…
- Trial name
- NCT06087809
- Testing
- Education and feedback, Clinical decision support
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston Children's Hospital
Anesthesia
Postdural Puncture Headache Relief With Aminophylline and SPGB
The purpose of the study is to compare Sphenopalatine ganglion block (SPGB) and aminophylline in the efficacy and safety management of PDPH.
- Trial name
- NCT05552404
- Testing
- conservative therapy, Aminophylline, trans nasal sphenopalatine ganglion block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Acute Exercise, Caffeine Withdrawal
The Acute Effects of Exercise and Caffeine on Working Memory During Acute Caffeine Deprivation
To determine the effects of moderate intensity exercise and caffeine on working memory in deprived caffeine consumers.
- Conditions
- Acute Exercise, Caffeine Withdrawal, Memory Deficits
- Trial name
- NCT05170464
- Testing
- Acute Exercise, Caffeine Powder
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Desire to Exercise, Exercise Training
Guayusa Extract on Exercise Training
Guayusa extract is a caffeinated Amazonian 'super-leaf' belonging to the holly species that contains a very unique blend of polyphenol antioxidants and caffeine (~20% caffeine, 30% chlorogenic acids, 5% catechins).
- Conditions
- Desire to Exercise, Exercise Training, Physical Exertion
- Trial name
- NCT05820399
- Testing
- Organic Guayusa Extract
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Nathaniel Jenkins
Healthy
Relative Bioavailability of Ibuprofen From a Single Fixed Dose Combination Tablet of Ibuprofen and Caffeine Compared to Single Tablets of Ibuprofen and Ibuprofen Lysinate
To investigate the relative bioavailability of ibuprofen from a (FDC) film-coated tablet of ibuprofen and caffeine vs. a tablet of ibuprofen (Brufen®) and a tablet of ibuprofen lysinate (Nurofen Immedia®).
- Trial name
- NCT01879371
- Testing
- Ibuprofen+caffeine FDC, Ibuprofen (Nurofen Immedia®), Ibuprofen (Brufen®)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Influenza, Human
Testing Multiple Behavioral Science Strategies to Increase Flu-Shot Rates
This research aims to identify which behavioral science strategies are most effective at increasing flu vaccination rates overall and based on patients' individual characteristics.
- Trial name
- NCT04565353
- Testing
- Flu shot text messages
- Where
- 2 sites in United States
- Volunteers
- 74,811 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Critical Limb Ischemia
An Efficacy and Safety Study of Ixmyelocel-T in Patients With Critical Limb Ischemia (CLI)
This study is designed to evaluate the efficacy and safety of ixmyelocel-T, a patient-specific expanded multicellular therapy, for the treatment of patients with critical limb ischemia (CLI).
- Trial name
- REVIVE (NCT01483898)
- Testing
- Ixmyelocel-T
- Where
- 86 sites in United States
- Volunteers
- 41 people
- Sponsor
- Vericel Corporation
Energy Metabolism, Heart Rate
Effects of a Thermogenic Dietary Supplement on Metabolic, Hemodynamic, and Mood Responses
This a randomized, double blind, placebo controlled, crossover design study which measures the effect of an available thermogenic dietary supplement on resting energy expenditure (REE), blood pressure and heart rate, and mood…
- Conditions
- Energy Metabolism, Heart Rate, Blood Pressure, Mood
- Trial name
- NCT03678116
- Testing
- Caffeine (plus Teacrine and Cayenne), Caffeine (plus Teacrine)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Mary Hardin-Baylor
Sodium, Caffeine
Study on Sodium and Caffeine in Children and Adolescents
This study will compare different methods (24 hour urine collection, evening and morning spots, and questionnaires) to measure the consumption of sodium and cafeine in children and adolescents.
- Trial name
- NCT02900261
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Pharmacokinetic Study in Healthy Volunteers
Kinetics of Yohimbine in Humans to Explore Sex and CYP2D6 Genotype Interactions
This study investigates the pharmacokinetics of yohimbine in women and men aged 18 to 40 years to explore sex-specific differences in CYP2D6-dependent drug metabolism.
- Trial name
- YOKI-1 (NCT06939608)
- Testing
- Yohimbine, ¹³C₃-caffeine
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Diarrhea, HIV Infections
The Healthy Life Choices Project in HIV-Positive Patients
This randomized clinical trial is designed to determine the efficacy of a dietary intervention to reduce the frequency of bowel movements and improve stool consistency as compared with subjects assigned to a control group.
- Trial name
- NCT00017810
- Testing
- Dietary intervention, HIV Self-Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Columbia University