Clinical trials: Caffeine, completed
Caffeine
Early Versus Routine Caffeine Administration in Extremely Preterm Neonates
Premature infants are at risk of having pauses in breathing, or apneas, due to their immaturity. Premature infants are routinely given caffeine, a respiratory stimulant, on the first day of life to prevent apneas.
- Trial name
- EARLYCAFFEINE (NCT01783561)
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Sharp HealthCare
Hypertension
Early-Warning Intervention for Heat and Cold in Older Hypertensive Patients: Impact on Sleep Quality
This cluster-randomized trial, conducted in Tianjin, China, aims to evaluate the effectiveness of integrating a digital health risk early warning tool for heat with self-monitoring.
- Trial name
- NCT06045403
- Testing
- Issuing health risk warning for a heat or cold, A digital heat or cold health risk early warning tool, Perform daily self-monitoring of their BP and ECG
- Where
- China
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Tiantian Li
Muscle Damage
Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.
Dietary supplements to enhance exercise and athletic performance come in a variety of forms, including tablets, capsules, liquids, powders, and bars.
- Trial name
- NCT06086691
- Testing
- Strength Training with Caffeine, Endurance Training with Caffeine
- Where
- Pakistan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Death, Cancer
Hospice and End-of-life Symptom Monitoring & Support Using an Automated System Designed for Family Caregivers
Improving end-of-life care and the suffering caused by poorly controlled symptoms is an important public health concern. The development of an automated telephone symptom monitoring and support system that assists caregivers in…
- Trial name
- SCP (NCT02112461)
- Testing
- SCP-Hospice Alert
- Where
- United States
- Volunteers
- 365 people
- Sponsor
- University of Utah
Healthy
Effects of Low Doses of Caffeine on Mood, Physiology and Mental Function
It is often assumed that levels of caffeine found in 'decaffeinated' beverages are below any psychopharmacological threshold. However, recent findings indicate that caffeine doses as low as 9 mg may be psychoactive.
- Trial name
- NCT00487227
- Testing
- caffeine
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Rheumatoid Arthritis
Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin
Drug-drug interaction study in healthy men and women not of childbearing potential. Assess the effect of BMS-986195 on the pharmacokinetics of methotrexate, caffeine, montelukast, flurbiprofen, omeprazole, midazolam, digoxin, and…
- Trial name
- NCT03131973
- Testing
- BMS-986195, Methotrexate, Leucovorin
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Supplementation During Endurance Performance
Pre-workout Supplement, Arrhythmias and Exercise Stress Test
Pre-workout supplements are widely used by physically active individuals to enhance exercise performance. These products typically contain stimulant substances such as caffeine, beta-alanine, arginine, and tyrosine, which act on…
- Trial name
- NCT07853066
- Testing
- Dietary Supplement
- Where
- Brazil
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Irritable Bowel Syndrome
Traditional Dietary Advice Vs. Mediterranean Diet in IBS
Irritable bowel syndrome (IBS) affects 5-10% of the population, and incurs substantial health impairment and healthcare utilization.
- Trial name
- NCT05985018
- Testing
- Traditional Diet, Mediterranean Diet
- Where
- United Kingdom
- Volunteers
- 139 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Healthy Subjects, Anaemia
A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy Subjects
This is a first time in human study to investigate the safety of GSK626616AC given as oral single and repeat doses in healthy subjects.
- Trial name
- NCT00443170
- Testing
- omeprazole, caffeine, flurbiprofen, rosiglitazone
- Where
- 3 sites in Australia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Headache Disorders, Primary, Migraine With Aura
IndoProCaf Effervescent Tablets Effectiveness in Acute Treatment of Migraine and/or Episodic Tension-type Headache and Patients' Satisfaction With the Treatment in Routine Clinical Practice
Headaches are a common medical problem that physicians frequently encounter in their practice. One of key findings of The Atlas of Headache Disorders prepared by World Health Organization (WHO) is: headache disorders, including…
- Conditions
- Headache Disorders, Primary, Migraine With Aura, Migraine Without Aura, Tension-Type Headache
- Trial name
- PRESTO (NCT02115269)
- Where
- 30 sites in Kazakhstan, Ukraine
- Volunteers
- 759 people
- Sponsor
- Abbott
Caffeine, Placebo
Neurophysiological Reserve With Caffeine Manipulation
The objective of this study is to verify if there is a neurophysiologic reserve when caffeine and placebo perceived as caffeine are manipulated in closed- and opened-loop exercises.
- Trial name
- NCT01167478
- Testing
- Caffeine
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Medication Abuse
A Health System Wide Evaluation of Clinical Decision Support Tools to Improve PDMP Utilization and Patient Outcomes
This is a study comparing three clinical decision support (CDS) tools to enhance care by easing health care provider review of the Colorado prescription drug monitoring program (PDMP) prior to prescribing opioids (pain…
- Trial name
- NCT04918355
- Testing
- Clinical Decision Support (CDS) alerts
- Where
- United States
- Volunteers
- 3,635 people
- Sponsor
- University of Colorado, Denver
Irritable Bowel Syndrome (IBS), Irritable Bowel Syndrome With Diarrhea (IBS-D)
Curcumin, Vitamin D and Green Tea in IBS-D
Irritable Bowel Syndrome (IBS) is a highly prevalent condition of the gastrointestinal tract that has significant impact on sufferer's quality of life. The diarrhoea variant (IBS-D) makes up around one third of all IBS sufferers.
- Trial name
- NCT07052890
- Testing
- Curcumin, vitamin d and green tea extract
- Where
- 3 sites in United Kingdom
- Volunteers
- 78 people
- Sponsor
- Dr Anthony Hobson
Healthy
A Drug-drug Interaction Study Between GLPG1205 and a Cocktail of CYP450 Substrates in Healthy Male Subjects
This will be a Phase I, randomized, double-blind, placebo-controlled, 2 period cross-over, drug-drug interaction study to evaluate the effect of multiple oral doses of GLPG1205 or placebo (daily from Day 1 to Day 12) on a single…
- Trial name
- NCT02623296
- Testing
- GLPG1205, Cocktail of CYP450 substrates
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Lakefront Biotherapeutics NV
Healthy, Caffeine
Effects of Variations in Caffeinated Beverages on Well-being
This study will evaluate post-beverage subjective caffeine responses and physiological responses to caffeinated beverage variations in generally healthy adults.
- Conditions
- Healthy, Caffeine, Beverage Intake
- Trial name
- NCT07404254
- Testing
- Caffeinated, low sugar beverage, Caffeinated beverage, Control beverage
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GUAYAKI SUSTAINABLE RAINFOREST PRODUCTS, INC.
Caffeine Dependence
A Long-term Safety and Efficacy of EnXtra (E-AG-01) in Healthy Adults
The present study has been proposed to investigate the long-term safety and efficacy of EnXtra in healthy adults habituated to caffeine.
- Trial name
- NCT03731286
- Testing
- Alpinia Galanga, Microcellulose crystalline
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Hyperemia, Hypoxia
Enhancement of Postocclusive Reactive Hyperaemia by Dipyridamole
The purpose of this study is to determine whether dipyridamole enhances postocclusive reactive hyperaemia by increasing extracellular adenosine concentrations during ischemia and reperfusion.
- Trial name
- NCT00268554
- Testing
- dipyridamole, caffeine
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Headache Disorders, Central Nervous System Diseases
Is Sphenopalatine Ganglion Block Treatment Effective on Postspinal Headaches
This study evaluates effect of sphenopalatine ganglion block in post dural puncture headache. Half of participants will receive standard supportive treatment and other half of patients will be performed sphenopalatine ganglion…
- Trial name
- SPG (NCT03512977)
- Testing
- sphenopalatine ganglion block, conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Derince Training and Research Hospital
Asthma
Effects of Caffeine on Methacholine Challenge and Exhaled Nitric Oxide Levels.
To investigate whether or not the ingestion of caffeine with alter airway responsiveness to methacholine and/or change the level of exhaled nitric oxide.
- Trial name
- NCT01057875
- Testing
- caffeine, No caffeine
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Saskatchewan
Caffeine, Athletic Performance
The Effects of Caffeine on Physical Performance of Ice Hockey Players
To date, only one study has evaluated the effect of caffeine supplementation on athletic performance in ice hockey players finding a lack of ergogenic effect.
- Trial name
- cafhoc (NCT05170139)
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza