Clinical trials: Caffeine
Healthy
Exploring the Cortical Hemodynamic Variability of Four Weeks iTBS on a Healthy Participant: a Case Study
This study will investigate the effect of caffeine and time of day on brain excitability using excitatory brain stimulation. The investigators will recruit a healthy participant and conduct a concurrent iTBS/fNIRS protocol for 20…
- Trial name
- NCT05427565
- Testing
- caffeine, Experimental time
- Where
- Hong Kong
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Healthy Male
A Study to Evaluate the Effects of D-1553 on PK of Midazolam, Caffeine, Rosuvastatin, Furosemide, Digoxin, and Itraconazole or Omeprazole on PK of D-1553
This is a phase I study to evaluate drug-drug interactions (DDIs) of D-1553 as a perpetrator combined with midazolam (CYP3A4 substrate), caffeine (CYP1A2 substrate), rosuvastatin (OATP1B1/OATP1B3 substrate), furosemide…
- Trial name
- NCT06105255
- Testing
- D-1553
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- InventisBio Co., Ltd
Placebo Effect, Drug Half Life
The Placebo Effect May Involve Modulating Drug Bioavailability
The total effect of a medication is the sum of its drug effect, placebo effect (meaning response of placebo), and their interaction.
- Conditions
- Placebo Effect, Drug Half Life, Pharmacokinetics
- Trial name
- NCT01501747
- Testing
- Caffeine, paracetamol, cephalexin, or ibuprofen
- Where
- Saudi Arabia
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- King Faisal Specialist Hospital & Research Center
Tinnitus
Effects of Caffeine in Tinnitus
Caffeine intake is reported by many authors to enhance the perception of tinnitus. The aim of this study is to determine the effects of 1 month caffeine intake reduction in the scores of validated questionnaire Tinnitus Handicap…
- Trial name
- NCT00628316
- Testing
- caffeine
- Where
- 2 sites in Brazil
- Volunteers
- 50 people
- Sponsor
- Faculdade de Medicina de Valenca
Athletic Performance
Study on How Pre-Workout Supplements Affect Shooting Accuracy in Trained Basketball Players
Basketball is a popular team sport where athletes score points by successfully shooting the ball into the basket. Accuracy in shooting is crucial for players to score points effectively.
- Trial name
- NCT06995209
- Testing
- Pre-workout Supplement
- Where
- Greece
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- International Hellenic University
Healthy
Caffeine Disposition After Inhalation
The purpose of this study is to determine how fast caffeine gets into your body with a product called Aeroshot™. Aeroshot™ is a lipstick sized device that you slide open and then put your mouth over the opening and inhale.
- Trial name
- NCT02184104
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Advanced Solid Tumors, Excluding Breast Cancer
Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors
This is a multi-center, open-label, phase I study to assess the effects of dovitinib (TKI258) on the pharmacokinetics of a cocktail of caffeine, diclofenac, omeprazole and midazolam in patients with advanced solid tumors…
- Trial name
- NCT01596647
- Testing
- caffeine, diclofenac, omeprazole
- Where
- 5 sites in United States
- Volunteers
- 39 people
- Sponsor
- Novartis Pharmaceuticals
Obesity, Overweight
A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body Weight
The purpose of this clinical study is to find out if UBT251 is safe and effective to be taken together with medicines, like midazolam, caffeine and warfarin in participants living with overweight or obesity.
- Trial name
- NCT07710768
- Testing
- UBT251, Cocktail (Warfarin/Caffeine/Midazolam)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Food-drug Interaction
Licorice Botanical Dietary Supplements - Metabolism and Safety in Women
Human safety studies will be carried out to test whether red clover botanical dietary supplements used by peri- and post-menopausal women are safe to use with Food and Drug Administration (FDA)-approved drugs.
- Trial name
- NCT03948243
- Testing
- Licorice, Alprazolam 2 MG, Caffeine 100 MG
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Meconium Aspiration Syndrome
CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO)
When babies are stressed in the womb, they sometimes pass meconium in the amniotic fluid. When this happens, they may swallow the meconium-stained fluid into their lungs which may cause them to have poor oxygen levels and require…
- Trial name
- CAPUCINO (NCT06972108)
- Testing
- Caffeine citrate
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Acute Insomnia Disorder
Impact of Analytic-integrative Cognitive Behavioural Therapy on Acute Insomnia Disorder (Stress)
The main objective of this study, conducted in a population with acute insomnia disorder (stress), was to investigate the efficacy of Analytic-Integrative Cognitive Behavioural Therapy in the treatment of acute insomnia disorder…
- Trial name
- NCT06967922
- Testing
- Analytic-Integrative Cognitive Behavioural Therapy, Sleep hygiene education
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Xuanwu Hospital, Beijing
Caffeine and Resistance Exercise
Reproducibility of Acute Caffeine Effect
Introduction: Various studies have evaluated and verified the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance.
- Trial name
- NCT06606639
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Breastfeeding
Milk Production and Body Weight Response to Suggested Protocol in Obese Lactating Women
This study will investigate the milk production and body weight response of both mother and the newborn to aerobic exercise in obese lactating women.
- Trial name
- NCT06975527
- Testing
- Breastfeeding guidelines, Aerobic exercise
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alzheimer Disease, Mild Cognitive Impairment
Investigating Brain Insulin Resistance in Alzheimer Disease with IntraNasal Insulin : a Multimodal Neuroimaging Study
Using simultaneous multimodal neuroimaging (FDG-PET, fMRI, EEG), this research project will aim to further investigate in vivo brain insulin signalling by exploring the effects of acute INI administration on neurometabolic and…
- Trial name
- Memori³ (NCT06391853)
- Testing
- Insulin
- Volunteers
- healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Caffeine, Burning Mouth Syndrome
Caffeine vs. ALA in BMS Treatment. (BMS: Burning Mouth Syndrome. ALA: Alpha-Lipoic Acid.)
The aim of this study was to evaluate the efficacy of caffeine and alpha-lipoic acid in the treatment of burning mouth syndrome by symptom assessment with visual analogue scale.
- Trial name
- NCT06195137
- Testing
- Caffeine, Alpha Lipoic Acid
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Lu Jiang
Morbid Obesity
Treatment of Low Metabolic Rate Following Bariatric Surgery
Purpose is to determine the effect of ephedrine and caffeine, on metabolic rate and weight loss after bariatric surgery. Approximately 40% of patients struggle with their weight loss rate, or metabolic rate, after bariatric…
- Trial name
- NCT01596907
- Testing
- Ephedrine sulfate with caffeine, cellulose
- Where
- 2 sites in United States
- Volunteers
- 218 people
- Sponsor
- Oregon Weight Loss Surgery, LLC
Hepatitis C
Advanced Electronic Population Health and Personal Health Record Tools to Improve Once Lifetime Hepatitis C Screening
This study involves randomizing patients due for once in a lifetime Hepatitis C screening based on Center for Disease Control and Prevention and United States Preventative Services Task Force guidelines in one of three primary…
- Trial name
- NCT03654365
- Testing
- Bulk ordering and bulk messaging, Routine alerting
- Volunteers
- 1,024 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Dietary Supplementation
Consumption of 4D Dietary Supplement on Perceptual-Cognitive and Visual-Motor Performance
The purpose of this investigation is to determine if supplementation with the 4D dietary supplement impacts perceptual-cognitive and visual-motor skills in healthy individuals.
- Trial name
- NCT04988919
- Testing
- 4D
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Migraine Disorders
Trial of Nortriptyline and Topiramate in the Initial Treatment of Vestibular Migraine
The investigators' study plans to randomize treatment naive patients with vestibular migraine to an 8 week trial of an escalating dose of either nortriptyline or topiramate followed by an 8 week crossover to the other drug if…
- Trial name
- NCT02169830
- Testing
- nortriptyline, Topiramate, Diet Modification
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- St. Louis University
Musculoskeletal Pain
Efficacy and Safety of the Combination of Ketoprofen and Cyclobenzaprine and Caffeine in Osteomuscular Treatment
The purpose of this study is to evaluate the safety and efficacy of an association with one anti-inflammatory and one muscle relaxant plus caffeine compared to one anti-inflammatory plus caffeine in the treatment of osteomuscular…
- Trial name
- NCT02862977
- Testing
- ketoprofen and cyclobenzaprine association with caffeine, Cyclobenzaprine with caffeine
- Where
- 6 sites in Brazil
- Volunteers
- 414 people
- Sponsor
- EMS
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