Clinical trials: Caffeine
Caffeine, Insufficient Sleep
Consequences of Caffeine Intake in Sleep Restricted Teenagers
The goal of this clinical trial is to systematically investigate two prominent factors in teenagers' daily life: Caffeine and sleep restriction (SR) and their combined influence on sleep, cognition, and behavior in healthy…
- Trial name
- NCT05790161
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Psychiatric Hospital of the University of Basel
Common Cold/Flu, Nasal Congestion
Fixed-dose Combination of 1000 mg Dipyrone Monohydrate + 60 mg Caffeine + 4 mg Chlorpheniramine Maleate in Improving Symptoms of the Common Cold and Flu in Adults
Phase III clinical trial to evaluate the efficacy and safety of a fixed-dose combination of 1000 mg dipyrone monohydrate + 60 mg caffeine + 4 mg chlorpheniramine maleate in improving symptoms of the common cold and flu in adults.
- Conditions
- Common Cold/Flu, Nasal Congestion, Nasal Obstruction
- Trial name
- PANAMA (NCT07626437)
- Testing
- dipyrone monohydrate 1000 mg + chlorpheniramine maleate 4 mg + caffeine 60 mg, dipyrone monohydrate 500 mg + chlorpheniramine maleate 2 mg + caffeine 30 mg
- Where
- 15 sites in Brazil
- Volunteers
- 620 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Caffeine Use Disorder (DSM-5 Condition for Further Study)
Treatment for Caffeine Dependence
Recent research has shown that some individuals become addicted to or dependent on caffeine and are unable to quit or reduce caffeine consumption despite a persistent desire to do so.
- Trial name
- NCT01951872
- Testing
- Manual-based treatment for caffeine dependence
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Johns Hopkins University
Dysphagia
Impact of Blocking the Glossopharyngeal Nerve on Gastroesophageal Reflux Disease
The goal of this clinical trial is to explore Clinical Effect of Glossopharyngeal Nerve Block on Pharyngeal Dysphagia Induced by Gastroesophageal Reflux Disease.
- Trial name
- NCT06304870
- Testing
- Rehabilitation therapy, Lidocaine, Injection
- Volunteers
- 80 people
- Sponsor
- Muhammad
Caffeine, Heart Rate Variability
Effect of Caffeine on Heart Rate Variability in Newborns
The aim of this study was to evaluate the impact of caffeine treatment, given either orally or intravenously, on heart rate variability in newborns.
- Conditions
- Caffeine, Heart Rate Variability, Apnoea of Newborn, Newborn
- Trial name
- NCT04869176
- Testing
- Electrocardiogram, Monitoring of vital functions, Caffeine Citrate 5 mg/kg
- Where
- Slovenia
- Volunteers
- 25 people
- Sponsor
- University of Ljubljana
Excessive Daytime Sleepiness, Disorders of Excessive Somnolence
Feasibility and Acceptability of a 6-Week Myofunctional and Physical Activity Program for University Students With Excessive Daytime Sleepiness
The aim of this clinical trial is to examine the feasibility, acceptability and safety of a 6-week intervention (MYOPAP) which includes oropharyngeal myofunctional therapy, physical activity guidance, and sleep hygiene education…
- Trial name
- MYOPAP (NCT07879859)
- Testing
- MYOPAP Program
- Where
- Kuwait
- Volunteers
- 14 people
- Sponsor
- Kuwait University
Healthy
Effect of Caffeine Consumption on Protein Biomarkers and Cardiovascular Disease
Caffeine is one of the most widely consumed substances worldwide. This study looks to test and measure the changes in different biomarkers in the blood before and after having caffeine using capillary and venous blood sampling…
- Trial name
- NCT06359197
- Testing
- Caffeine Pill, TASSO+ Device, Finger prick and collection on Whatman Protein 903 Saver Cards
- Where
- 3 sites in Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Cerebral Perfusion, Contraception
The Effects of the Female Hormones on Cerebral Perfusion
Measuring brain perfusion is biased by a inter- and intrasubject variability, caused by physiological and lifestyle factors. In this study, the investigators want to investigate the variations in cerebral perfusion and other…
- Conditions
- Cerebral Perfusion, Contraception, Menstrual Cycle
- Trial name
- NCT03299179
- Testing
- MRI scan, Physiological monitoring, Blood sample
- Where
- Belgium
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Ghent
Emergence From Anesthesia
Turning Dexmedetomidine Into a Powerful Anesthetic That Can be Rapidly and Completely Reversed
In this study, the investigators will explore Atipamezole \& caffeine's ability to facilitate the emergence from anesthesia. Each subject will visit UChicago 4 times. The first time for informed consent.
- Trial name
- NCT04942340
- Testing
- Atipamezole & Caffeine, Dexmedetomidine Hydrochloride & Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Cold Exposure, Manual Dexterity
Cocoa-rich Bioflavanol Supplementation Effects During Cold Exposure
The primary purpose is to test whether cocoa-rich bioflavanols can improve blood flow to the hand and fingers and improve hand function/dexterity during cold exposure.
- Conditions
- Cold Exposure, Manual Dexterity, Gut Microbiome
- Trial name
- NCT04359082
- Testing
- CocoaVia supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Cancer
The Effect of Gamified Sleep Hygiene Education on Sleep Quality and Fatigue Levels in Chemotherapy Patients
Sleep disturbances and fatigue are common problems among patients receiving chemotherapy and may negatively affect their quality of life.
- Trial name
- NCT07809386
- Testing
- Gamified Sleep Hygiene Education, Standard Sleep Hygiene Education
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Lokman Hekim University
Energy Drinks
Effects of Energy Drinks
This study is designed to test the efficacy of energy drinks. This is a double-blinded, crossover, randomized clinical trial, measuring the effect of the test drinks compared with placebo drink in 200 participants aged 18-70…
- Trial name
- NCT02727920
- Testing
- Energy drink
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Sleep
Brief Behavioral Intervention to Maintain Sleep Regularity in Young Adults Over the Christmas Break
This study will employ a randomized controlled trial design to investigate the effects of a brief behavioral intervention that includes (1) self-recording of a regularity-focused sleep diary, (2) 10 strategies for maintaining…
- Trial name
- REST (NCT07056179)
- Testing
- Brief behavioural intervention, Health education
- Where
- Hong Kong
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Cardiovascular Diseases, Acute Coronary Syndrome
In-Hospital Wearable-Based Monitoring Versus Standard Care in Cardiovascular Disease (INSPIRE)
Patients hospitalized with cardiovascular disease require timely detection of clinical deterioration to prevent adverse outcomes.
- Conditions
- Cardiovascular Diseases, Acute Coronary Syndrome, Heart Failure, Cardiac Arrhythmia
- Trial name
- NCT07622485
- Testing
- thynC Inpatient Monitoring System
- Where
- South Korea
- Volunteers
- 1,500 people
- Sponsor
- Yonsei University
Asthma, Asthma Attack
Evaluating Asthma Exacerbation-induced Changes in Lung Function With a Home-based Spirometer
The investigators will study the use of a home-based spirometer (Spirobank Smart spirometer) that connects to a smartphone app (VitalFlo) in teenagers with persistent asthma to determine if clinically significant changes in lung…
- Conditions
- Asthma, Asthma Attack, Asthma, Allergic
- Trial name
- NCT03705325
- Testing
- Spirobank Smart spirometer
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- VitalFlo Inc.
Diabetes Mellitus, Hyperglycemia
DPBRN Blood Sugar Testing in Dental Patients
The principal goal of this study was to assess the feasibility of plasma glucose testing in private dental practice. A second aim was was to assess prevalence of plasma glucose abnormalities in dental patients seen by (DPBRN)…
- Trial name
- NCT01201460
- Where
- 7 sites in United States, Denmark
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Moderate to Severe Plaque Psoriasis
Open Label, Single Dose, Non-randomized Study to Assess the Drug to Drug Interaction of Briakinumab on CYP Substrates.
Phase 1, drug-drug interaction study to evaluate the effects of Briakinumab on hte pharmacokinetics of single doses of CYP substrate in subjects with moderate to severe psoriasis.
- Trial name
- NCT01260844
- Testing
- briakinumab
- Volunteers
- 12 people
- Sponsor
- Abbott
Cardiovascular Injury
Synthetic and Natural Caffeine on Hemodynamic Parameters in Young, Healthy Volunteers
The purpose of this study determine the difference in hemodynamic effects of synthetic and natural caffeine consumption in healthy individuals through blood pressure (central and peripheral) assessment.
- Trial name
- NCT03495063
- Testing
- Natural Caffeine, Synthetic Caffeine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Narcolepsy
The Effect of Caffeine on the Narcoleptic Patients
Caffeine may be playing a beneficial role in patients with narcolepsy. However, the relationship between caffeine and its effects on narcoleptic patients has not been examined, and it is also unclear whether caffeine provides a…
- Trial name
- NCT02832336
- Testing
- Vivarin, Fiber
- Where
- Saudi Arabia
- Volunteers
- 16 people
- Sponsor
- King Saud University
Healthy
Timing of Meal and Caffeine Intake on Substrate Use and Exercise Efficiency
During the past decades, considerable emphasis has been directed to analyzing the potential role of caffeine on substrate use and exercise performance.
- Trial name
- NCT04106752
- Testing
- Caffeine
- Where
- Lebanon
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
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