Clinical trials: Caffeine
Unauthorized Data Access
The Effectiveness of Email Alerting on Reducing Employees' Unauthorized Access to Protected Health Information
To assess the effectiveness of email warnings on reducing repeated unauthorized access to Protected Health Information (PHI), a randomized trial was conducted in a large academic medical center to understand the effectiveness of…
- Trial name
- NCT05251844
- Testing
- receiving an email
- Where
- United States
- Volunteers
- 444 people
- Sponsor
- Protenus, Inc.
Crohn Disease, Ulcerative Colitis
A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Active Crohn's Disease or Ulcerative Colitis
The purpose of this study is to evaluate the potential effects of an intravenous (IV) induction and subcutaneous (SC) maintenance administration of ustekinumab on the pharmacokinetic (PK) of a cocktail of representative probe…
- Trial name
- NCT03358706
- Testing
- Ustekinumab IV Infusion, Ustekinumab SC Injection, Midazolam 2 mg
- Where
- 16 sites in United States, Belgium and 2 more
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Soreness, Muscle, Performance Enhancing Product Use
Acute Study on Muscle Soreness, Damage, and Performance
The acute study will evaluate pre- and post-exercise ingestion of a multi-ingredient supplement in a randomized, double-blind, placebo-controlled, crossover design.
- Conditions
- Soreness, Muscle, Performance Enhancing Product Use, Damage Muscle
- Trial name
- NCT04230226
- Testing
- Pre-workout plus and protein recovery plus
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Hand Skill, Relative
Impact of Energy Drinks on the Manual Dexterity of Final Year Dental Students
This study aims to test the hypothesis that there was a relationship between the consumption of energy drinks and the manual dexterity skills of final year dental students.
- Trial name
- NCT02535143
- Testing
- Test Cavity Preparation, Taurine, Post intervention test cavity
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Cortical Excitability, Brain Stimulation
Neuroplastic Alterations of the Motor Cortex by Caffeine
Caffeine is a psychostimulant drug. It acts as a competitive antagonist at adenosine receptors, which modulate cortical excitability as well.
- Conditions
- Cortical Excitability, Brain Stimulation, Caffeine
- Trial name
- NCT04011670
- Testing
- 200 mg caffeine tablet, Non-active tablet
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Arrhythmia
Arrhythmic Effects of Hight Dose Caffeine
Heart failure patients represent a group of individuals at higher risk for cardiac arrhythmias. There is a perception that caffeine consumption may represent an increase in this risk.
- Trial name
- NCT02045992
- Testing
- caffeine
- Where
- Brazil
- Volunteers
- 112 people
- Sponsor
- Luis Eduardo Paim Rohde
Interstitial Lung Disease, Interstitial Pulmonary Fibrosis
Enhancing Physical Activity in Patients With Interstitial Lung Disease
The level of physical activity (PA) has been shown to be an important predictor for morbidity and mortality in patients with chronic respiratory diseases such as COPD and more recently Idiopathic Pulmonary Fibrosis.
- Trial name
- NCT04138173
- Testing
- Tele coaching intervention
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- KU Leuven
Sleep Disturbance, Sleep Deprivation
Impact of Bed Provision and Sleep Education
Investigators will recruit up to 100 families (children aged 8-12 years and their primary caregivers) from the Philadelphia-area Beds for Kids charity program, which provides beds, bedding, and sleep education to…
- Conditions
- Sleep Disturbance, Sleep Deprivation, Sleep, Insomnia
- Trial name
- NCT04536766
- Testing
- Enhanced Sleep Health Education, Beds for Kids Standard Program
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Saint Joseph's University, Philadelphia
Healthy
Impact of AMATEA™️ on Physiological Measures and Gaming Performance in Active Gamers: a Placebo Controlled, Double-blind, Randomized Study
AMATEA™ is a patented dietary supplement consisting of a unique blend of caffeine and polyphenol antioxidants; standardized at 20% caffeine, 30% chlorogenic acids (similar to green coffee).
- Trial name
- NCT04234529
- Testing
- AMATEA™, Caffeine
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Apnea, Preterm Infants
High Versus Low Dose of Caffeine for Apnea of Prematurity
The optimum caffeine dose for apnea of prematurity has not been well investigated so the objective of the study is to compare high versus low dose of caffeine citrate to facilitate successful extubation in mechanically ventilated…
- Trial name
- NCT02103777
- Testing
- Caffeine citrate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University Children Hospital
Mental Fatigue, Alertness
Effect of Coffeeberry on Mood and Cognitive Performance
The primary aim of this randomised, double-blind, placebo-controlled, cross-over study is to assess the short-term cognitive effects of two beverages containing 100 and 300 mg coffeeberry extract (obtained from the fruit of the…
- Conditions
- Mental Fatigue, Alertness, Mood, Cognition
- Trial name
- NCT04975802
- Testing
- Coffeeberry, Caffeine
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Irritable Bowel Syndrome
Effect of Pilates Exercises on Patients With Irritable Bowel Syndrome
purpose: to investigate the effect of pilates exercises on patients with irritable bowel syndrome. Methods sixty patients with IBS will be recruited and randomly assigned into two groups, group A and group B.
- Trial name
- NCT05832801
- Testing
- ( Traditional dietary advice ), (Pilates exercises)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Cognition, Mood
Investigation of the Acute Effects of Nepalese Pepper Extract (Zanthoxylum Armatum DC) on Cognitive Function, Mood and Gaming Performance in Young, Healthy, Competitive Gamers
The goal of this clinical trial is to learn if a Nepalese Pepper Extract (Zanthoxlum Armatum, ZA) supplement can improve cognitive performance and mental abilities in competitive gamers aged 16 to 34.
- Conditions
- Cognition, Mood, Gaming Performance, Fatigue
- Trial name
- NCT07047105
- Testing
- Nepalese Pepper (Zanthoxylum Armatum) extract 150mg, Nepalese Pepper (Zanthoxylum Armatum) extract 300mg, Caffeine 75mg
- Where
- United Kingdom
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Overactive Bladder (OAB)
Efficacy of Probiotics for OAB Patients With Anxiety
The goal of this clinical trial is to learn if probiotics can help improve symptoms in adults with overactive bladder (OAB) and anxiety. The main questions it aims to answer are: 1.
- Trial name
- NCT07635212
- Testing
- Multi-strain Probiotic Compound
- Where
- China
- Volunteers
- 218 people
- Sponsor
- Qilu Hospital of Shandong University
Non-Epileptic Seizure, Motor Seizure
An Exploratory Trial Using sEMG to Differentiate PNES From Epileptic Seizures
This is an observational study of subjects receiving standard of care therapy, while admitted to Epilepsy Monitoring Unit, Department of Neurology, General Hospital Hietzing with Neurological Center Rosenhügel.
- Conditions
- Non-Epileptic Seizure, Motor Seizure, Epilepsy
- Trial name
- NCT03169751
- Testing
- Brain Sentinel Monitoring and Alerting System
- Where
- Austria
- Volunteers
- 71 people
- Sponsor
- Brain Sentinel
Diabetes Mellitus, Type 1
Sleep Promotion to Improve Diabetes Management in Adolescents With T1D
Adolescents with type 1 diabetes (T1D) are at increased risk for problems with adherence and suboptimal glycemic control, and novel approaches are needed to improve outcomes in this high-risk population.
- Trial name
- NCT02786953
- Testing
- Sleep Promotion
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
Multiple Myeloma
Teclistamab in Combination With Daratumumab for High-Risk Smoldering Myeloma: A Clinical and Correlative Phase 2 Immuno-Oncology Study (the REVIVE Study)
The purpose of this study is to see whether combination treatment of Teclistamab and Daratumumab (Tel-Dara) or combination Talquetamab and Daratumumab (Tal-Dara) will delay the onset of multiple myeloma.
- Trial name
- REVIVE (NCT06100237)
- Testing
- Teclistamab, Talquetamab, Daratumumab SC
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Carl Ola Landgren, MD, PhD
Post-menopause
Mental Stress Reactivity in Women With CMD
Coronary Microvascular Dysfunction (CMD) occurs when there are problems in the small blood vessels/arteries of the heart, resulting in persistent chest pain that affects women.
- Trial name
- NCT05401630
- Testing
- Study Procedures
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- Emory University
Healthy
Food Matrix Effect on Flavanol Absorption, Metabolism and Excretion: Methylxanthines
Dietary intervention study in healthy young adult males to evaluate concentration of flavanol metabolites in plasma and urine after single acute intakes of methylxanthines.
- Trial name
- NCT03526107
- Testing
- CF Control, CF-Theobromine, CF-Caffeine
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Aerial Duel Performance in Soccer Players
Combined Caffeine and Rhodiola Rosea on Aerial Duel Performance in Soccer
This study will examine whether caffeine (CAF) and Rhodiola rosea (RHO) supplementation, taken alone or in combination, can improve explosive performance and soccer-specific aerial duel performance in trained male soccer players.
- Trial name
- CCRP-AD (NCT07458594)
- Testing
- Caffeine, Rhodiola rosea extract
- Where
- 2 sites in China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
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