Clinical trials: Caffeine, completed
Mental Fatigue
The Effect of a Caffeine Blend on Reaction Time, Mental Performance and Focus in Athletic Males
This is a cross-over design study in which subjects arrived to the lab and were assigned a supplement to ingest. Prior to ingestion subjects completed baseline reaction time testing along with a questionnaire.
- Trial name
- NCT03019523
- Testing
- Caffeine Blend, Sugar Pill
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Mary Hardin-Baylor
Colon Cancer, Lynch Syndrome
Integrating Genetic Testing for Lynch Syndrome in a Managed Care Setting
The investigators research mobilizes the resources of an integrated health-delivery system with extensive electronic clinical data to implement and evaluate a new strategy to maximize screening of Colorectal Cancer (CRC) patients…
- Trial name
- HNPCC (NCT01582841)
- Testing
- MSI screening test
- Where
- United States
- Volunteers
- 247 people
- Sponsor
- Kaiser Permanente
Premature Lungs, Respiratory Distress Syndrome
Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants
This study is being conducted to determine whether prophylactic administration of surfactant by the Less Invasive Surfactant Administration (LISA) method reduces the need for mechanical ventilation in the first 72 hours of life…
- Conditions
- Premature Lungs, Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal
- Trial name
- CaLI (NCT04209946)
- Testing
- Less Invasive Surfactant Administration LISA, Continuous Positive Airway Pressure CPAP
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- Sharp HealthCare
Heart Failure
Health Information Technology in Heart Failure Care
The objective of this proposal is to develop, implement, and test the effectiveness of a computerized clinical decision support system for hospitalized patients with heart failure.
- Trial name
- NCT02858674
- Testing
- Pop Up Interruption Alert, Side Bar Non Interruptive Provider Checklist
- Where
- United States
- Volunteers
- 958 people
- Sponsor
- NYU Langone Health
Drug Biotransformation, Membrane Transport
Repeated Dose Study for the Investigation of Heritability of and Genetic Influences on Drug Pharmacokinetics
This human pharmacokinetic study investigates, whether processes of drug metabolism and transport are determined by genetic or hereditary factors.
- Trial name
- NCT01845194
- Testing
- Codeine, Midazolam, Pravastatin
- Where
- Germany
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH
The Focus of the Study is Healthy Volunteers
Understanding the Effects of Daily Tea Consumption on Attention, Sleep, and Mood, in Healthy Adults
The goal of these series of N-of-1 trials is to compare the effects of three tea interventions on cognition, mood, and sleep, in healthy adult participants.
- Trial name
- Reactivi-Tea (NCT06224569)
- Testing
- Black tea flavoured, tea drink, Black tea flavoured, caffeine-only drink, Green tea flavoured, tea drink
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Insomnia
Effect of Activated Charcoal and Time of Dose on the Pharmacokinetics of LY2624803 in Healthy Subject
The purpose of this study is to determine the effect of activated charcoal and dosing time on the absorption of LY2624803 in healthy subjects.
- Trial name
- NCT01236105
- Testing
- LY2624803, Activated Charcoal
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Heart Failure, Heart Failure With Reduced Ejection Fraction
Evaluating Strategies to Improve Guideline Directed Medical Therapy: The GDMT Research, Education & Assist Trial for Heart Failure Care
Heart failure with reduced ejection fraction (HFrEF) is associated with high mortality and adverse events (hospitalization or urgent outpatient visits for HF), along with diminished quality of life.
- Trial name
- GREAT-HF Care (NCT05990296)
- Testing
- Multiprong CDS with referral to pharmacist co-management, Multiprong CDS with GDMT order set, Focused education
- Where
- United States
- Volunteers
- 4,306 people
- Sponsor
- Geisinger Clinic
Sleep Disruption, Sleep Hygiene
Sleep Hygiene During Ramadan
Ramadan fasting often disrupts sleep patterns, which can affect alertness and physical performance in student-athletes. This study tested whether a brief sleep education program designed for Ramadan could help improve sleep…
- Conditions
- Sleep Disruption, Sleep Hygiene, Ramadan Fasting
- Trial name
- SHIR (NCT07639229)
- Testing
- Culturally Adapted Sleep Hygiene Education Program
- Where
- Tunisia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax
Healthy
Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers
Primary: To quantify the influence of single-dose and steady-state tipranavir/ritonavir 500/200 mg on intestinal and hepatic cytochrome P450 (CYP) and P-glycoprotein (P-gp) biomarkers, as a means of predicting drug interactions.
- Trial name
- NCT02243553
- Testing
- Tipranavir capsule, Tipranavir solution, Ritonavir capsule
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Caffeine
Effects of Caffeine in Hydration and Energy Metabolism
The main purposes of this randomized cross-over trial are to characterize and compare the effects of a moderate dose of caffeine intake in healthy physically active males on hydration and energy metabolism specifically: 1.
- Trial name
- NCT01477294
- Testing
- Caffeine
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Technical University of Lisbon
Reflexology, Dietary Modification
Foot Reflexology on Premenstrual Syndrome
: Premenstrual Syndrome (PMS) is a set of physical, emotional and behavioral symptom that start during the week preceding menstruation and are alleviated when the menstrual flow begins.
- Trial name
- NCT04348201
- Testing
- foot reflexology, dietary modification
- Volunteers
- 50 people
- Sponsor
- Cairo University
Attention Deficit Hyperactivity Disorder
Effects of L-theanine and Caffeine on Attention and Attention-related Brain Activity of Children With Attention Deficit Hyperactivity Disorder
L-theanine and caffeine are two natural constituents of tea. Both of these compounds are among the U.S. Food and Drug Administration's list of Generally Recognized as Safe (GRAS) substances.
- Trial name
- NCT03533556
- Testing
- L-theanine, Caffeine, L-theanine-Caffeine Combination
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Cognitively Healthy Subjects Influenced by Psychoactive Drugs
Cognitive Hyper-performance - Effects of Stimulating Substances in Chess-players
Effects of caffeine, methylphenidate, modafinil and placebo on cognitive performance of chess players in chess games and neuropsychiatric standardized tests.
- Trial name
- CHESS (NCT01834547)
- Testing
- Drugs use: methylphenidate, Drug use: modafinil, caffeine
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- K. Lieb
Fatigue, Mental Alertness
A Study to Evaluate the Effect of EnXtra® and EnXtra® + Caffeine on Mental Alertness and Fatigue in Healthy Individuals
Acute Stage: The present study is a randomized, double-blind, placebo-controlled, single-dose, 4-way, cross-over, study. Approximately not more than 170 individuals will be screened and considering a screening failure rate of…
- Trial name
- NCT06560008
- Testing
- EnXtra® (300 mg) + Caffeine (200 mg)
- Where
- 3 sites in India
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Caffeine Dependence, Anxiety
Remote Guided Caffeine Reduction
The purpose of this online research study is to determine whether or not a gradual caffeine reduction program developed at Johns Hopkins can help people reduce their caffeine use.
- Conditions
- Caffeine Dependence, Anxiety, Sleep Disturbance, Gastrointestinal Dysfunction
- Trial name
- NCT04560595
- Testing
- Caffeine Reduction Manual
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
COPD
Long-term Activity Coaching in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of mortality and morbidity around the world. Studies revealed that patients with COPD are less active than age-matched healthy controls and activity level decreases…
- Trial name
- NCT04139200
- Testing
- Type 1 physical activity tele coaching intervention, Type 2 physical activity tele coaching intervention
- Where
- 2 sites in Belgium
- Volunteers
- 150 people
- Sponsor
- KU Leuven
Postoperative Delirium, Postoperative Cognitive Dysfunction
The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study
The objective of this study is to test the effects of caffeine on neurocognitive and clinical recovery after major surgery. Specifically, this trial tests the primary hypothesis that caffeine will reduce the incidence of…
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Mild Cognitive Impairment
- Trial name
- NCT05574400
- Testing
- Dextrose Water, Caffeine citrate
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Michigan
Atherosclerosis, Cardiovascular Disease
Is Augmentation of PORH by Rosuvastatin Adenosine-receptor Mediated?
Rationale: Statins form a class of drugs that is widely prescribed for hypercholesterolaemia, specifically to reduce the risk on atherosclerosis by lowering LDL-cholesterol.
- Trial name
- NCT00851175
- Testing
- rosuvastatin, caffeine
- Where
- Netherlands
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Abnormal Labor, Failed Induction of Labor
Enhanced vs. Routine Clear Liquid Intake in Labor
The goal of the study is to see if the addition of a carbohydrate- and protein-enhanced gel during labor speeds labor and reduces the rate of cesarean delivery.
- Conditions
- Abnormal Labor, Failed Induction of Labor, Ketosis
- Trial name
- NCT02524002
- Testing
- Accel Gel, Usual clear diet
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Temple University