Clinical trials: Caffeine, open to volunteers
Type 1 Diabetes Mellitus
Physical Activity to Prevent and Treat Hyperglycemia From a Mistimed Bolus Insulin Dose
People living with type 1 diabetes (PwT1D) are recommended to administer insulin 10-15 minutes before meal consumption (pre-bolus), to account for the delay in the glucose lowering action associated with subcutaneously…
- Trial name
- Missed Dose (NCT06686329)
- Testing
- Control (CON), Missed Dose (MISS), Missed Dose + 15min walk (MISS+EX)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Jane Yardley
COPD (Chronic Obstructive Pulmonary Disease), COPD Exacerbations
The REVIVE Pivotal Study
The goal of this study is to test whether a new treatment called the Ryme Medical Targeted Lung Denervation (TLD) Catheter is safe and effective for people with moderate to severe chronic obstructive pulmonary disease (COPD).
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), COPD Exacerbations, COPD Patients, COPD Acute Exacerbation
- Trial name
- REVIVE (NCT07361653)
- Testing
- Ryme TLD
- Volunteers
- 300 people
- Sponsor
- Ryme Medical, Inc.
Laryngopharyngeal Reflux Disease
Comparative Effectiveness of Alginate, Magaldrate, Sucralfate, Proton Pump Inhibitors, and Diet in Laryngopharyngeal Reflux Disease
The goal of this randomized controlled trial is to compare the effectiveness of different treatments for laryngopharyngeal reflux disease (LPRD) in adult patients with confirmed symptoms and signs of the condition.
- Trial name
- NCT07611162
- Testing
- Alginate, Magaldrate, Sucralfate
- Where
- Belgium
- Volunteers
- 800 people
- Sponsor
- University of Mons
Overactive Bladder (OAB)
Efficacy of Probiotics for OAB Patients With Anxiety
The goal of this clinical trial is to learn if probiotics can help improve symptoms in adults with overactive bladder (OAB) and anxiety. The main questions it aims to answer are: 1.
- Trial name
- NCT07635212
- Testing
- Multi-strain Probiotic Compound
- Where
- China
- Volunteers
- 218 people
- Sponsor
- Qilu Hospital of Shandong University
Alcohol Abuse/Dependence
Examining the Relationship Between Physical Activity Levels and Chronotype Tendencies in Individuals With Alcohol Dependence
Alcohol use disorders are characterized by excessive alcohol consumption and loss of control and are associated with high mortality and disease burden.
- Trial name
- NCT06850428
- Where
- Turkey (Türkiye)
- Volunteers
- 207 people
- Sponsor
- Gulhane School of Medicine
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Di-PKD: A Pilot Trial of Dietary Intervention in Patients With Autosomal Dominant Polycystic Kidney Disease
The goal of this interventional study is to evaluate the impact of a specific diet (low salt, limited caffeine, high potassium, low phosphate, limited protein, limited carbohydrate intake, adequate water intake) on changes in…
- Trial name
- ADPKD (NCT06786260)
- Testing
- Interventional Diet
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Loma Linda University
Migraine, Migraine Disease
Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals
Caffeine extracted from green tea to abort acute attack of Migraine
- Conditions
- Migraine, Migraine Disease, Migraine Headache, Migraine Headache, With or Without Aura
- Trial name
- NCT07022496
- Testing
- Caffeine (200 mg), triptans, NSAID (Nonsteroidal anti-inflammatory drugs)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Atrial Fibrillation (AF), Permanent Atrial Fibrillation
Caffeine Consumption and Rate Control in Permanent Atrial FIBrillation: The CAFIB Trial
The CAFIB trial is a multicenter, randomized, open-label, crossover clinical trial designed to determine whether habitual caffeine consumption in coffe adversely affects rate control in patients with permanent atrial fibrillation…
- Conditions
- Atrial Fibrillation (AF), Permanent Atrial Fibrillation, Coffee Consumption, Caffeine Abuse
- Trial name
- CAFIB (NCT07738523)
- Testing
- Dietary Caffeine Intake
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Universitario Getafe
Meconium Aspiration Syndrome
CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO)
When babies are stressed in the womb, they sometimes pass meconium in the amniotic fluid. When this happens, they may swallow the meconium-stained fluid into their lungs which may cause them to have poor oxygen levels and require…
- Trial name
- CAPUCINO (NCT06972108)
- Testing
- Caffeine citrate
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Healthy
Variation in the Impact of Coffee on the Metabolic Rate
The purpose of this study is to explore variation in the impact of coffee on metabolic rate. The investigators plan to recruit healthy participants, half male and half female.
- Trial name
- NCT06432504
- Testing
- Caffeine content
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Depression, Anxiety
A Mindfulness-Based Stress Reduction Training Program Model
Mindfulness-based practices are used to regulate mood, alleviate or completely eliminate symptoms that cause stress and depression, and positively influence well-being.
- Conditions
- Depression, Anxiety, Stress, Well-Being, Psychological
- Trial name
- NCT07544355
- Testing
- The mindfulness group-"Mindfulness-Based Stress Reduction Program", The life skills workshop group-"Lifestyle Management and Well-being Workshop"
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Stressor, Individual, Alcohol Impairment
Neurobehavioral Changes Following Spaceflight Stressors
This study aims to investigate the impairing effects of known central nervous system (CNS) stressors in a controlled environment in order to predict and mitigate analogous risks in spaceflight.
- Conditions
- Stressor, Individual, Alcohol Impairment, Sleep Deprivation, Impairment, Cognitive
- Trial name
- NeuroSTAR (NCT07293494)
- Testing
- Alcohol Administration, Sleep Deprivation, Control
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Lower Back Pain, Kinesio Taping
The Effect of Kinesio Taping Applied to Operating Room Nurses on Low Back Pain, Fatigue, and Sleep Quality
This study aims to determine the effects of kinesiology taping applied to operating room nurses on lower back pain, fatigue, and sleep quality.
- Trial name
- NCT06758687
- Testing
- Kinesiotape Application
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Chronic Insomnia
Effects of Sleep Restriction and Stimulus Control in Chronic Insomnia Patients
The study aims to validate the effect of sleep restriction and stimulus control on improving chronic insomnia patients\' sleep habits and maladaptive sleep behaviors.
- Trial name
- NCT06658184
- Testing
- sleep restriction and stimulus control, sleep hygiene education
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xuanwu Hospital, Beijing
Osteo Arthritis Knee and Hip
Predicting The Right Advice at The Right Time in Patients With Hip and Knee OsteoArthritis: the e-cOAch Cross-over.
This study aims to learn how symptoms and daily functioning change over time in people with hip or knee osteoarthritis (OA). The goal is to use this information to build computer models that can predict these changes.
- Trial name
- e-cOAch (NCT07423858)
- Testing
- Physical Activity program, Sleep program, Weight management program
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- UMC Utrecht
Drowsiness, Sleep Deprivation
TESTING AN MTM THEORY-BASED INTERVENTION ON REDUCING DROWSY DRIVING BEHAVIOR, "STAY AWAKE, STAY ALIVE ©," AMONG COLLEGE STUDENTS
The goal of this randomized controlled educational study is to learn whether a structured, theory-based program can help reduce drowsy driving among college students (18 years and older) in Nevada.
- Conditions
- Drowsiness, Sleep Deprivation, Fatigue
- Trial name
- NCT07434921
- Testing
- MTM Theory based intervention, Standard AAA Knowledge based
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Healthy Adult Participants
A Multiple-dose Study Investigating the Drug-drug Interaction Potential and QTc Effects of Fosmanogepix in Healthy Adult Subjects
This is a Phase 1, fixed-sequence, multiple-dose study in approximately 42 healthy adult participants. The study will be conducted in two parts.
- Trial name
- NCT07881224
- Testing
- Fosmanogepix, The medicine cocktail (caffeine, bupropion, flurbiprofen, omeprazole, dextromethorphan and midazolam), Probe substrates (repaglinide, rosuvastatin, and digoxin)
- Where
- Netherlands
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Basilea Pharmaceutica
Sleep Initiation and Maintenance Disorders, Insomnia
Mindfulness Meditation for Insomnia
The investigators will conduct a 3-arm, pilot RCT where participants (N=30) will be randomized in a 1:1:1 design to 4 weeks of instructed bedtime MM practice at night (n=10) vs. uninstructed MM (n=10) vs.
- Conditions
- Sleep Initiation and Maintenance Disorders, Insomnia, Insomnia Chronic, Mindfulness
- Trial name
- NCT06972303
- Testing
- Instructed bedtime app-guided mindfulness meditation, Uninstructed app-guided mindfulness meditation, Sleep hygiene education
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Circadian Rhythm, Time Perception
Circadian Timing and Time Perception in Healthy Adults
This study examines how a person's natural daily rhythm ("chronotype") affects the way time is experienced and judged. Healthy Danish-speaking adults (23-45 years) who are clearly morning-type or evening-type will complete two…
- Trial name
- ChronoTime (NCT07292597)
- Testing
- Session timing relative to chronotype
- Where
- Denmark
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cognitive Assessment, Working Memory
Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.
The proposed project will evaluate the synergistic effects of a nutritional formulation, 'Think Tank' on cognitive performance following exposure to a psychological and physical stressor.
- Conditions
- Cognitive Assessment, Working Memory, Executive Function (Cognition), Sustained Attention
- Trial name
- NCT07319117
- Testing
- Skoshify 'Think Tank' Formulation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University