Clinical trials: Celecoxib, completed
Osteoarthritis, Knee
Efficacy and Safety of Lumiracoxib in Patients With Knee Osteoarthritis (OA).
This study will investigate the efficacy and safety of lumiracoxib in patients with primary knee osteoarthritis (OA).
- Trial name
- NCT00366938
- Testing
- Lumiracoxib
- Where
- United States
- Volunteers
- 1,464 people
- Sponsor
- Novartis
Amyotrophic Lateral Sclerosis
Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis
The objective of this study is to compare two combinations of drugs, minocycline and creatine or celecoxib and creatine, in a phase II trial designed to determine which combination is more effective for ALS.
- Trial name
- NCT00355576
- Testing
- Celecoxib, Creatine, Minocycline
- Where
- 19 sites in United States
- Volunteers
- 86 people
- Sponsor
- Columbia University
Nausea
Nausea in Patients Receiving Hydromorphone vs Oxycodone After Total Hip Replacement Surgery
The study aims to compare the incidence of side effects caused by Oxycodone and Hydromorphone.
- Trial name
- NCT02295124
- Testing
- Oxycodone, Hydromorphone
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University Health Network, Toronto
Osteoarthritis
GI-Reasons- A Trial Of GI Safety Of Celecoxib Compared With Non-Selective Nonsteroidal Antiinflammatory Drugs (NSAIDS)
This study investigates if Celebrex has a lower incident of Gastrointestinal Events than other NSAIDS in subjects with osteoarthritis.
- Trial name
- GI-REASONS (NCT00373685)
- Testing
- Celecoxib, Any commercially available NSAID with the indication for osteoarthritis
- Where
- 777 sites in United States, Puerto Rico
- Volunteers
- 8,067 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Acute Kidney Injury
Acute Kidney Injury After Elective Total Joint Arthroplasty
Total joint arthroplasty (TJA) is a common orthopedic procedure to treat patients with end-stage knee arthritis. Over 4,000 TJA were performed in the Hong Kong public hospitals in the past 12 months (July 2020 - June 2021) and…
- Trial name
- NCT05595694
- Testing
- No intervention
- Where
- Hong Kong
- Volunteers
- 1,077 people
- Sponsor
- The University of Hong Kong
Osteoarthritis, Hip
Celecoxib Versus Diclofenac In The Treatment Of Osteoarthritis Of The Hip
To determine if celecoxib 200 mg once daily is as effective as diclofenac 50 mg three times daily in the treatment of pain symptoms associated with osteoarthritis of the hip
- Trial name
- NCT00174317
- Testing
- Celecoxib, Diclofenac
- Where
- 44 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- Pfizer
Lumbar Surgery
Enhanced Recovery After Surgery in Orthopaedic Spine Surgery
This study aims to determine the impact and effect of enhanced recovery after surgery (ERAS) principles in the recovery and rehabilitation of patients following elective orthopaedic spine surgery with a specific emphasis on oral…
- Trial name
- ERAS (NCT04562610)
- Testing
- Intravenous Infusion group, All oral administration group
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of California, Davis
Acute Pain
Efficacy and Safety in a Randomised Acute Pain Study of MR308: STARDOM2.
The MR308-3502 study is a multicenter double-blind, randomised, placebo- and active comparator-controlled study in female subjects to evaluate the efficacy and safety of MR308 with acute pain after TAH or STAH (total or subtotal…
- Trial name
- STARDOM2 (NCT03062644)
- Testing
- MR308
- Where
- 8 sites in Belarus, Bulgaria and 6 more
- Volunteers
- 1,138 people
- Sponsor
- Mundipharma Research GmbH & Co KG
Osteoarthritis
Efficacy and Safety of Lumiracoxib
This trial assessed the safety and efficacy of a single dose of lumiracoxib 400 mg compared to placebo and to a single dose of celecoxib 200mg.
- Trial name
- NCT00267215
- Testing
- Lumiracoxib
- Where
- Germany
- Volunteers
- 330 people
- Sponsor
- Novartis
Spondylitis, Ankylosing
Safety and Efficacy of Celecoxib Versus Diclofenac in the Treatment of Ankylosing Spondylitis
To compare the safety and efficacy of once-daily and twice-daily celecoxib versus diclofenac for the treatment of ankylosing spondylitis
- Trial name
- NCT00648141
- Testing
- Celecoxib, Diclofenac
- Where
- 47 sites in Germany
- Volunteers
- 458 people
- Sponsor
- Pfizer
Breast Cancer
Protocol for Women at Increased Risk of Developing Breast Cancer
To assess the effects of twelve months of celecoxib administration by evaluating breast tissue needle aspirations, to determine if cell growth can be slowed.
- Trial name
- NCT00291694
- Testing
- celecoxib
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Compare Unimodal and Multimodal Analgesics
Multimodal and Unimodal Analgesia in Cholecystectomy
Many surgical procedures are accompanied by postoperative pain with severity moderate, severe or extreme and insufficient postoperative pain control may cause risk of post-surgical complications and risk of chronic post-surgical…
- Trial name
- NCT05547659
- Testing
- Pregabalin 150mg, Acetaminophen 1 G Oral Tablet, Celecoxib 400Mg Oral Capsule
- Where
- 2 sites in Egypt
- Volunteers
- 95 people
- Sponsor
- October 6 University
Ankle Sprain
Open Label Comparative Study On Celecoxib Efficacy And Safety Vs Non-Selective NSAID In Acute Pain Due To Ankle Sprain
To assess the efficacy of celecoxib loading dose of 400mg followed by 200 mg twice a day (BID) versus oral non-selective NSAIDs in acute pain due to ankle sprain.
- Trial name
- NCT00446797
- Testing
- Non-selective NSAIDS, Celecoxib
- Where
- 16 sites in Brazil, Costa Rica and 6 more
- Volunteers
- 278 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Migraine
Study on the Pharmacokinetics (PK) of DFN-15 vs Comparator and Food-effect on DFN-15 PK in Healthy Adult Subjects
An Open-Label, Three-Way Randomized, Single Dose Crossover Study Comparing Bioavailability of DFN-15 under fasting conditions versus Comparator under fed conditions and to determine food-effect of DFN-15 in Healthy Adult Subjects
- Trial name
- NCT03282838
- Testing
- DFN-15 (fasted), DFN-15 (fed), Comparator Celebrex® (fed)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Brainstem Glioma
ANGIOCOMB Antiangiogenic Therapy for Pediatric Patients With Diffuse Brain Stem and Thalamic Tumors
The purpose of this study is to determine whether initial local irradiation with topotecan and following oral antiangiogenic drugs, thalidomide, celecoxib and etoposide are effective in the treatment of pediatric diffuse…
- Trial name
- NCT01756989
- Testing
- Thalidomide, etoposide, celecoxib
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Helsinki University Central Hospital
Ankle (Ligaments); Instability (Old Injury), Ankle Sprain
A Study on Reducing Opioid Use After Ankle Arthroscopy
Study Title Effect of a Postoperative Multimodal Analgesic Protocol Predominantly Based on Non-Opioid Medications vs Opioid-Based Analgesia on Pain After Ankle Arthroscopy: A Noninferiority Randomized Clinical Trial Purpose This…
- Conditions
- Ankle (Ligaments); Instability (Old Injury), Ankle Sprain, Talus Osteochondral Defect, Opioid Analgesia
- Trial name
- NCT07154433
- Testing
- Opioid Analgesic Regimen, Non-opioid analgesic regimen
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Migraine Headache
Efficacy, Tolerability, and Safety Study of DFN-15
Efficacy, Tolerability, and Safety of DFN-15 in episodic migraine with or without aura, being conducted at multiple centers in the United States.
- Trial name
- NCT03006276
- Testing
- DFN-15 Active
- Where
- 45 sites in United States
- Volunteers
- 622 people
- Sponsor
- BioDelivery Sciences International
Arthritis, Gastric Ulcer
Effect of Selective COX-2 Inhibition on Ulcer Healing
The purpose of this study is to compare the effect of Famotidine plus a COX-2 inhibitor (celecoxib) with Famotidine plus dologesics in ulcer healing in arthritis patients.
- Trial name
- NCT00153673
- Testing
- celecoxib, Dologesics
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Relapsed Multiple Myeloma
ATRA, Celecoxib, and Itraconazole as Maintenance
The purpose of this study is to evaluate the safety and tolerability associated with the combination of ATRA/celecoxib/itraconazole as maintenance therapy given after an autologous stem cell transplant in relapsed multiple…
- Trial name
- NCT02401295
- Testing
- ATRA, Celecoxib, Itraconazole
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Iowa
Osteoarthritis, Peptic Ulcer
A Comparison of Safety and Treatment in Subjects With Osteoarthritis Taking Low Dose Aspirin
The purpose of this study is to compare the gastroduodenal ulceration rate, gastrointestinal complication rate and non-steroidal anti-inflammatory drug-associated dyspepsia between lansoprazole, naproxen and celecoxib, taken once…
- Trial name
- NCT00175032
- Testing
- Lansoprazole and naproxen and aspirin, Celecoxib and aspirin
- Volunteers
- 1,045 people
- Sponsor
- Takeda