Clinical trials: Celecoxib, completed
ACL Tear, Post Operative Pain
Impact of Opioid Avoidance Protocol for ACL Reconstruction
This is a prospective, quasi-experimental, cohort study comparing patients treated with one of two postoperative pain management protocols.
- Trial name
- NCT06340932
- Testing
- Iovera, Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Matthew Varacallo
Neuroblastoma
N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan
This study will combine an oral drug called DFMO with celecoxib (also oral) and two IV chemotherapy medicines called cyclophosphamide and topotecan.
- Trial name
- DFMO (NCT02030964)
- Testing
- DFMO, Celecoxib, Cyclophosphamide
- Where
- 13 sites in United States, Australia and 1 more
- Volunteers
- 30 people
- Sponsor
- New Approaches to Neuroblastoma Therapy Consortium
Knee Osteoarthritis, Arthroplasty Complications
Pre vs Post Block in Total Knee Arthroplasty (TKA)
The purpose of this project is to determine if a change in patient reported pain, nausea and vomiting after total knee arthroplasty can be observed with the substitution of a post operative adductor canal block for a preoperative…
- Conditions
- Knee Osteoarthritis, Arthroplasty Complications, Postoperative Pain
- Trial name
- NCT05974501
- Testing
- Dexamethasone, Acetaminophen, Lyrica
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Miami
Long COVID, PASC Post Acute Sequelae of COVID 19
Valacyclovir Plus Celecoxib for Post-Acute Sequelae of SARS-CoV-2
To explore the safety and efficacy of daily doses of celecoxib + valacyclovir in the treatment of patients with prolonged symptoms caused by COVID-19.
- Trial name
- PASC (NCT06316843)
- Testing
- Valacyclovir celecoxib dose 1, Valacyclovir celecoxib dose 2
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Bateman Horne Center
Low Back Pain
Radial Extracorporeal Shock Wave Therapy for Chronic Non-specific Low Back Pain
This study tests the hypothesis that radial extracorporeal shock wave therapy (rESWT) in combination with the non-steroidal anti-inflammatory drug Celecoxib and the antispasmodic drug Eperisone (hereafter, "C-E drug therapy") is…
- Trial name
- NCT03337607
- Testing
- rESWT, Celecoxib, Eperisone
- Where
- China
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Breast Cancer, Breast Cancer Female
PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery
In this double blinded randomized placebo-controlled trial, 160 subjects scheduled for breast surgery involving the axilla will be administered a multimodal pain regimen including acetaminophen, dexamethasone, celecoxib, and…
- Conditions
- Breast Cancer, Breast Cancer Female, Cancer of Breast
- Trial name
- NCT03084536
- Testing
- Bupivacaine, Gabapentin, Celecoxib
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Washington University School of Medicine
Pain, Postoperative, Urethral Stricture
Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty
The investigator's study aims to see if an enhanced recovery regimen of pain medications before and during surgery will decrease the use and risk of opioid pain medications as well as improve pain control in anterior…
- Trial name
- NCT03859024
- Testing
- Oxycodone, Acetaminophen, Gabapentin
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Alabama at Birmingham
Osteoarthritis
A Study of MK0663 and an Approved Drug in the Treatment of Osteoarthritis (0663-076)(COMPLETED)
The purpose of this study is to compare the safety and effectiveness of an investigational drug and an approved drug in the treatment of osteoarthritis of the knee and hip.
- Trial name
- NCT00092768
- Testing
- MK0663, etoricoxib, Comparator: celecoxib
- Volunteers
- 500 people
- Sponsor
- Organon and Co
Osteoarthritis
A Study of MK0663 and an Approved Drug in the Treatment of Osteoarthritis (0663-077)(COMPLETED)
The purpose of this study is to compare the safety and effectiveness of an investigational drug and an approved drug in the treatment of osteoarthritis of the knee and hip.
- Trial name
- NCT00092781
- Testing
- MK0663, etoricoxib, Comparator: celecoxib
- Volunteers
- 500 people
- Sponsor
- Organon and Co
Opioid Use
A Multimodal Analgesia Protocol Adapted for Ambulatory Surgery
The primary objective of this trial is to determine whether the combination of three non-opioid analgesics (multimodal analgesia) can significantly reduce or eliminate the need for opioids after ambulatory surgery.
- Trial name
- NCT04015908
- Testing
- Celecoxib, Acetaminophen, Pregabalin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Recurrent Neuroblastoma
Metronomic Treatment in Children and Adolescents With Recurrent or Progressive High Risk Neuroblastoma
Neuroblastoma is the second most frequent cause for death from cancer in childhood. Already one year after diagnosis of recurrence from high risk neuroblastoma, 75% of the patients experience further progression.
- Trial name
- METRO-NB2012 (NCT02641314)
- Testing
- metronomic therapy
- Where
- 8 sites in Germany
- Volunteers
- 18 people
- Sponsor
- University of Cologne
Bipolar Depression
Cyclooxygenase-2-Inhibitor Combination Treatment for Bipolar Depression
This project will attempt to enhance and augment the antidepressant efficacy of a commonly used antidepressant in poorly responding bipolar depressed patients.
- Trial name
- NCT01479829
- Testing
- Escitalopram, Celecoxib
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Loyola University
Rotator Cuff Tear
Nonopioid Analgesia After Rotator Cuff Repair
This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of rotator cuff repair: a treatment group given a…
- Trial name
- NCT03818919
- Testing
- Celecoxib, Ketorolac, Gabapentin
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Low Back Pain
Evaluation of Clinical Efficacy of Herbal Compound in the Treatment of NSLBP
The aim of this randomized controlled trial was to explore the clinical efficacy and safety of HXTL in the treatment of NSLBP based on TCM principles and to compare the clinical outcomes of different syndromes of NSLBP with…
- Trial name
- NCT06336993
- Testing
- herbal compound, Celecoxib
- Where
- China
- Volunteers
- 71 people
- Sponsor
- Zhejiang Provincial Tongde Hospital
Pain, Postoperative
Preemptive Analgesia With Celecoxib for Acute Dental Pain Management
The purpose of this study is to compare the effect on postoperative pain of a single agent nonsteroidal anti-inflammatory drug (NSAID) [celecoxib plus placebo] to an NSAID combination [celecoxib plus acetaminophen] administered…
- Trial name
- NCT04790812
- Testing
- Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Solid Tumor, Adult
RACIN in Patients With Advanced TIL-negative Solid Tumors
Subjects with locally advanced or metastatic incurable Tumor Infiltrating Lymphocytes (TIL)-negative solid tumors who are not eligible for, declined or failed standard therapy will be treated with a combination nivolumab…
- Trial name
- RACIN (NCT03728179)
- Testing
- Low dose irradiation + Nivolumab + Ipilimumab or Cyclophosphamide + Aspirin/Celecoxib
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Ligament Injury
Correlation Between Acute Analgesia and Long-Term Function Following Ankle Injuries
In this 4-arm pragmatic randomized control trial, the investigators hope to decipher whether the use of non-opioid analgesics (naproxen, celecoxib, acetaminophen) in addition to standardized physiotherapy during the acute phase…
- Trial name
- CALF (NCT02667730)
- Testing
- Acetaminophen, Naproxen, Celecoxib
- Where
- Canada
- Volunteers
- 168 people
- Sponsor
- Canadian Department of National Defence
Pain, Postoperative
Celecoxib in Postoperative Analgesia for Radius Fracture Surgery
Patients scheduled for elective osteosynthesis of the distal radius will be randomized to receive celecoxib 100 mg orally (PO) at 6 in the morning before surgery and every 12 hours for 2 days thereafter, or a placebo pill in the…
- Trial name
- NCT05288374
- Testing
- Celecoxib 100 mg
- Where
- 2 sites in Czechia
- Volunteers
- 42 people
- Sponsor
- Charles University, Czech Republic
Submental Fat
Evaluation the Effects of Various Treatments on RZL-012-Induced Adverse Events
This is a Phase 2, open-label, 2-stage, adaptive-design study in which subjects will be randomized into one of 5 treatment groups comprised of RZL-012 with or without additional study treatments:
- Trial name
- NCT05476679
- Testing
- RZL-012, RZL-012+Lidacaine injection prior treatment, RZL-012+Medrol
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Raziel Therapeutics Ltd.
Postoperative Pain, Acute
Pain Treatment With Combinations of NSAIDs
The search for new safe and effective methods of pain relief after surgery on large joints is still an urgent problem. The most optimal approach in the treatment of postoperative pain is the use of multimodal analgesia with a…
- Trial name
- NCT05994287
- Testing
- Aspirin, Ketorolac, Celecoxib
- Where
- Russia
- Volunteers
- 105 people
- Sponsor
- Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty