Clinical trials: Celecoxib, completed
No Evidence of Disease
Celecoxib in Preventing the Damaging Effects of Sunburn in Healthy Volunteers
This randomized clinical trial studies if celecoxib will prevent the damaging effects of sunburn in healthy volunteers. Exposure to ultraviolet light can induce erythema, sunburn or skin redness caused by inflammation.
- Trial name
- NCT02099136
- Testing
- UV Light Therapy, Celecoxib, Biopsy
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Osteoarthritis, Knee
Safety and Efficacy of Celecoxib Versus Naproxen in the 6-month Treatment of Knee Osteoarthritis
To compare the safety and efficacy of celecoxib versus naproxen for the treatment of knee osteoarthritis
- Trial name
- CLOAK (NCT00643799)
- Testing
- Celecoxib, Naproxen
- Where
- 51 sites in United States
- Volunteers
- 586 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Osteoarthritis of the Knee
Safety and Efficacy of Two Dosages of Diractin® in Osteoarthritis (OA)
The purpose of this study is to provide replicated evidence of safety and efficacy of 50 mg and 100 mg ketoprofen in Diractin®.
- Trial name
- NCT00716547
- Testing
- ketoprofen in Diractin®, celecoxib
- Where
- 4 sites in Czechia, Germany and 2 more
- Volunteers
- 1,399 people
- Sponsor
- IDEA AG
Recurrent Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer
Erlotinib Hydrochloride With or Without Celecoxib in Treating Patients With Stage IIIB-IV Non-Small Cell Lung Cancer
RATIONALE: Erlotinib hydrochloride and celecoxib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Celecoxib may also stop the growth of lung cancer by blocking blood flow to the tumor.
- Conditions
- Recurrent Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
- Trial name
- NCT00499655
- Testing
- erlotinib hydrochloride, celecoxib, laboratory biomarker analysis
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- City of Hope Medical Center
Tobacco Use Disorder
Zileuton With or Without Celecoxib As Chemopreventive Agents in Smokers
The goal of this clinical research study is to learn how zileuton alone or the combination of zileuton and celecoxib may affect certain chemicals in the body that may be linked with a risk for smoking-related lung disease.
- Trial name
- NCT01021215
- Testing
- Zileuton, Celecoxib, laboratory biomarker analysis
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- National Cancer Institute (NCI)
Postoperative Pain, Thyroidectomy
Celecoxib for Reducing Morphine Requirement After Thyroid Surgery: A Randomized Controlled Trial
The purpose of this study is to determine whether celecoxib is effective in the treatment postoperative pain after thyroidectomy.
- Conditions
- Postoperative Pain, Thyroidectomy, Cyclooxygenase 2 Inhibitors
- Trial name
- NCT00520338
- Testing
- celecoxib
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Healthy Volunteers
A Study of LY3127760 in Healthy Participants
The main purposes of this study are to evaluate the safety and how well the body handles single and multiple doses of increasing strength of study drug, LY3127760. This study includes three parts.
- Trial name
- NCT01968070
- Testing
- LY3127760, Celecoxib
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Triple -Negative Breast Cancer, Estrogen Receptor Negative
Chemokine Modulation Therapy and Pembrolizumab in Treating Participants With Metastatic Triple-Negative Breast Cancer
This pilot trial studies how well chemokine modulation therapy works when given prior to pembrolizumab in treating participants with triple-negative breast cancer that has spread to other places in the body.
- Conditions
- Triple -Negative Breast Cancer, Estrogen Receptor Negative, HER2/Neu Negative, Anatomic Stage IV Breast Cancer AJCC
- Trial name
- NCT03599453
- Testing
- Biopsy, Chemokine Modulation Therapy, Celecoxib
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Roswell Park Cancer Institute
Anaplastic Glioma of Brain, Glioblastoma Multiforme
6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients
The goal of this clinical research study is to learn if the combination of 6-Thioguanine, Xeloda (capecitabine), and Celebrex (celecoxib) with Temodar (temozolomide) or Lomustine (CCNU) is effective in the treatment of recurrent…
- Conditions
- Anaplastic Glioma of Brain, Glioblastoma Multiforme, Brain Cancer
- Trial name
- NCT00504660
- Testing
- Capecitabine, Celecoxib (Celebrex), Temozolomide
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- M.D. Anderson Cancer Center
Coronary Arteriosclerosis
Effects of Celecoxib After Percutaneous Coronary Intervention
Several studies including ours have reported that celecoxib improves endothelium-dependent vasodilation and reduces inflammation and neointimal hyperplasia.
- Trial name
- NCT00292721
- Testing
- Celecoxib
- Where
- South Korea
- Volunteers
- 260 people
- Sponsor
- Seoul National University Hospital
Hip Arthroplasty, Knee Arthroplasty
Effect of Combined Use of Naloxone and Tramacet on Postop Analgesia in Elderly Patients Having Joint Replacement Surgery
Patients over 70 years of age, scheduled for joint replacement surgery will be randomized to tramacet/ naloxone plus morphine PCA or to morphine PCA to assess quality of analgesia in the postoperative period.
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, Spinal Anesthesia
- Trial name
- NCT00679614
- Testing
- tramacet, naloxone, tramacet, Acetaminophen
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Head and Neck Cancer, Lung Cancer
Celecoxib in Treating Patients With Early-Stage Head and Neck Cancer or Non-Small Cell Lung Cancer
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of celecoxib may be an effective way to prevent the recurrence of stage I or stage II head and neck…
- Trial name
- NCT00058006
- Testing
- celecoxib, adjuvant therapy
- Where
- 4 sites in United States
- Sponsor
- Northwestern University
Advanced Esophageal Cancers, Primary Small Cell Lung Cancers
Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion With or Without Concurrent Celecoxib in Subjects With Pulmonary and Pleural Malignancies
Background: Previously we have demonstrated induction of tumor antigen and tumor suppressor gene expression in lung cancer cells following exposure to the DNA demethylating agent, Decitabine (DAC).
- Conditions
- Advanced Esophageal Cancers, Primary Small Cell Lung Cancers, Non-Small-Cell Lung Carcinoma, Pleural Mesotheliomas
- Trial name
- NCT00037817
- Testing
- Decitabine, Depsipeptide, Celecoxib
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Cancer Institute (NCI)
Obstructive Sleep Apnea, Hypertension
Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans
The study has been designed to assess the effect of cyclooxygenase inhibition on blood pressure, cerebral blood flow, ventilation and renal hemodynamics following chronic intermittent hypoxia exposure.
- Conditions
- Obstructive Sleep Apnea, Hypertension, Cardiovascular Diseases, Stroke
- Trial name
- NCT01280006
- Testing
- Intermittent hypoxia, Indomethacin, Celecoxib
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Osteoarthritis
A Study of MK0663 and an Approved Drug in the Treatment of Osteoarthritis (0663-076)(COMPLETED)
The purpose of this study is to compare the safety and effectiveness of an investigational drug and an approved drug in the treatment of osteoarthritis of the knee and hip.
- Trial name
- NCT00092768
- Testing
- MK0663, etoricoxib, Comparator: celecoxib
- Volunteers
- 500 people
- Sponsor
- Organon and Co
Arthropathy of Knee, Anesthesia
IPACK Nerve Block for Total Knee Arthroplasty
Double-blind, randomized controlled clinical trial to test the efficacy of IPACK on postoperative opioid consumption, patient satisfaction, pain scores, mobility, and several other secondary outcomes in adults undergoing primary…
- Trial name
- NCT03921034
- Testing
- Ropivacaine, Saline
- Volunteers
- 72 people
- Sponsor
- Ochsner Health System
Pain, Postoperative
Effectiveness and Safety of Different Doses of BI 1026706 in Patients With Postoperative Dental Pain
To investigate the effectiveness of BI 1026706 powder for reconstitution of an oral solution compared to placebo and the relative effectiveness compared to Celecoxib.
- Trial name
- NCT02084511
- Testing
- BI 1026706, Celecoxib
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Boehringer Ingelheim
Spondylarthropathies, Magnetic Resonance Imaging
Effects of Nonsteroidal Anti-inflammatory Drug (NSAID) on Inflammatory Lesion of Axial Spondyloarthritis
Axial Spondyloarthritis (SpA) is a kind of inflammatory arthritis which includes ankylosing spondylitis. Common symptoms of axial SpA are inflammatory back pain, morning stiffness, peripheral arthritis, enthesitis.
- Trial name
- NCT03190603
- Testing
- Celecoxib
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Armed Forces Capital Hospital, Republic of Korea
Knee Osteoarthritis
Study of the Effect of Chondroitin Sulfate on Structural Changes in Knee Osteoarthritis Patients Assessed by MRI
The main purpose of this study is to compare the cartilage volume loss at the Baseline visit and after 24 months of treatment in patients treated with CHONDROITIN SULPHATE (CONDROSAN) 1200 mg daily vs.
- Trial name
- MOSAIC (NCT01354145)
- Testing
- Chondroitin sulfate, Celecoxib
- Where
- 5 sites in Canada
- Volunteers
- 194 people
- Sponsor
- Bioiberica
Osteoarthritis
An Efficacy, Safety and Effects on Quality of Life of Tramadol/Paracetamol as Add-on Therapy in Chronic Osteoarthritis
The purpose of this study is to evaluate the efficacy, safety and effects on Quality of Life (QOL) of tramadol/paracetamol (APAP) as an add-on therapy (medication taken in addition to another medication) in Filipino participants…
- Trial name
- NCT01728246
- Testing
- Tramadol/Paracetamol (APAP), Non-Tramadol/APAP
- Where
- Philippines
- Volunteers
- 473 people
- Sponsor
- Janssen Pharmaceutica